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Phd Cryo Electron Microscopy Jobs (NOW HIRING)

Cogent Scientific

Expert Pharma Biochemist

Louisville, CO

$40K - $54K/yr

Preparing and optimizing samples for single-particle cryo-electron microscopy (cryo-EM): complex ... PhD in Biochemistry, Molecular Biology, Structural Biology, Biophysics, or related field. * Hands ...

Cogent Scientific

Expert Pharma Biochemist

Louisville, CO · On-site

$40K - $54K/yr

Preparing and optimizing samples for single-particle cryo-electron microscopy (cryo-EM): complex ... PhD in Biochemistry, Molecular Biology, Structural Biology, Biophysics, or related field. * Hands ...

Cogent Scientific

Expert Pharma Biochemist

Louisville, CO · On-site

$115K - $125K/yr

Preparing and optimizing samples for single-particle cryo-electron microscopy (cryo-EM): complex ... PhD in Biochemistry, Molecular Biology, Structural Biology, Biophysics, or related field. * Hands ...

Cogent Scientific

Expert Pharma Biochemist

Louisville, CO · On-site

$120 - $170/hr

Preparing and optimizing samples for single-particle cryo-electron microscopy (cryo-EM): complex ... PhD in Biochemistry, Molecular Biology, Structural Biology, Biophysics, or related field. * Hands ...

University of Colorado

Post-Doctoral Fellow

Aurora, CO · On-site

$49K - $67K/yr

By employing high-resolution cryo-electron microscopy (cryo-EM) and tomography (cryo-ET), we aim to ... PhD or equivalent doctoral degree in Membrane biology, Structural Biology, Biochemistry, or a ...

Uw

Research Scientist/Engr 4

Seattle, WA · On-site

$122K/yr

Single particle cryo-electron microscopy and X-ray crystallization of viral glycoproteins, immunogen design, virology, biochemistry and biophysics. Purpose of the Research Project(s): The goal of our ...

University of Colorado

Post-Doctoral Fellow

Aurora, CO · On-site

$49K - $67K/yr

By employing high-resolution cryo-electron microscopy (cryo-EM) and tomography (cryo-ET), we aim to ... PhD or equivalent doctoral degree in Membrane biology, Structural Biology, Biochemistry, or a ...

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Phd Cryo Electron Microscopy information

What is a PhD in cryo electron microscopy?

A PhD in Cryo-Electron Microscopy (Cryo-EM) is a doctoral program focused on using advanced electron microscopy techniques to study the structures of biological molecules at near-atomic resolution. Students in this field develop expertise in sample preparation, imaging, and data analysis to better understand the form and function of proteins, viruses, and other complex biomolecules. Graduates often contribute to scientific research in fields such as structural biology, biochemistry, and drug discovery.

What are the key skills and qualifications needed to thrive as a PhD cryo electron microscopy specialist?

To thrive as a PhD Cryo Electron Microscopy (Cryo-EM) specialist, you need a strong background in structural biology, biochemistry, and physics, typically supported by a doctoral degree in a related field. Expertise in operating advanced cryo-EM instruments, image processing software (such as RELION or CryoSPARC), and familiarity with data analysis pipelines is essential. Attention to detail, problem-solving ability, and effective collaboration skills help you excel when troubleshooting experiments and working within multidisciplinary teams. These competencies are crucial for generating high-quality structural data and advancing scientific discoveries in molecular biology.

What are some common challenges faced by PhD researchers specializing in cryo electron microscopy, and how can they be addressed?

PhD researchers in Cryo Electron Microscopy (Cryo-EM) often encounter challenges such as sample preparation issues, data collection bottlenecks, and interpreting complex datasets. Achieving optimal sample vitrification and minimizing beam-induced motion are technical hurdles that require patience and meticulous technique. Collaborating closely with experienced microscopists, leveraging advanced image processing software, and participating in specialized training workshops can greatly assist in overcoming these obstacles. Additionally, working in multidisciplinary teams fosters knowledge sharing and accelerates problem-solving, making it easier to advance high-impact structural biology projects.

What is the difference between Phd Cryo Electron Microscopy vs Phd Structural Biology?

AspectPhd Cryo Electron MicroscopyPhd Structural Biology
Required CredentialsPhD in relevant field, microscopy expertisePhD in biology, biochemistry, or related field
Work EnvironmentLaboratories with advanced microscopy equipmentResearch labs, academic institutions, biotech companies
Industry UsageUsed for high-resolution imaging of biomoleculesUsed for understanding biological structures and functions
Common Search/ComparisonOften compared for research focus and techniquesBroader biological context

While both roles require advanced degrees and involve biological research, Phd Cryo Electron Microscopy specializes in imaging techniques to visualize biomolecules at near-atomic resolution. Phd Structural Biology encompasses a broader understanding of biological structures, often integrating various methods including cryo-EM. The choice depends on whether the focus is on imaging technology or biological function analysis.

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Phd Cryo Electron Microscopy jobs near you
Infographic showing various Phd Cryo Electron Microscopy job openings in the United States as of August 2026, with employment types broken down into 1% Internship, 89% Full Time, 7% Part Time, and 3% Contract. Highlights an 83% Physical, 5% Hybrid, and 12% Remote job distribution.

Expert Pharma Biochemist

Cogent Scientific

Louisville, CO

$40K - $54K/yr

Full-time

Medical, Dental, Vision, Retirement, PTO

Re-posted yesterday

Job description

Cogent Scientific, an insourced contract research organization, is looking for the right people to accomplish our Mission: to support the life sciences industry by cultivating and empowering exceptional scientists to deliver specialized laboratory services that advance research, foster collaboration, and accelerate innovation through quality and a shared commitment to excellence. We can offer you the chance to build on your skills and knowledge while working among experts in their fields and with cutting-edge instrumentation.


Cogent Scientific offers competitive pay, attractive benefits (such as medical/dental/vision insurance; 401(k); parental leave; PTO and paid holidays; etc.) and an exciting work environment. This position may include relocation benefits as well. We aim to recruit the best people who stand out among their peers and embody our Core Values:


  • Client Focused: We only succeed when our clients succeed.
  • Outstanding: We deliver meticulous results through outstanding performance.
  • Good: We act ethically and morally.
  • Employee-Centric: We honor and support our employees.
  • Nimble: We are prepared to adapt in an ever-changing industry.
  • Team-Oriented: We collaborate with each other and with our clients.


We currently have a role available for an Expert Pharma Biochemist.


Job duties include, but are not limited to, the following:


  • Characterizing protein-protein interactions between targets and engineered binders using biophysical methods (mass photometry, analytical SEC, SEC-MALS, SPR, or BLI).
  • Preparing and optimizing samples for single-particle cryo-electron microscopy (cryo-EM): complex assembly, negative-stain/grid screening, vitrification, and iterative optimization.
  • Coordinating with internal/external cryo-EM imaging partners on grid screening and data collection.
  • Maintaining thorough electronic lab notebook records for reproducibility and traceability.


Job requirements include, but are not limited to:


  • PhD in Biochemistry, Molecular Biology, Structural Biology, Biophysics, or related field.
  • Hands-on experience in protein biochemistry (expression/purification, chromatography) and protein-protein interaction characterization (e.g., mass photometry, SPR, BLI, ITC, or AUC).
  • Familiarity with electron microscope sample preparation (negative stain and/or cryo-electron microscopy grid prep/screening).
  • Excellent communication skills - verbal and written.
  • Works well both as a team and as an individual.
  • Demonstration of excellent team player skills, very strong attention to detail, very strong problem-solving skills, a high level of learning agility, and the ability to work across functions. The ideal candidate will be enthusiastic and self-motivated, with the leadership and communication skills necessary to operate effectively in a fast-paced multidisciplinary environment with flexibility and an adaptable approach to goal delivery.


This is a day shift position (approx. 8a-5p local time).


Cogent Scientific provides equal employment opportunities to all applicants and does not discriminate based on any legally protected characteristic.


Additionally, if you require a reasonable accommodation during the application or interview process, please let us know.


This job posting will remain open until 9/14/2026 or until a qualified candidate has been selected, whichever comes first.

Apply