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Phd Cryo Electron Microscopy Jobs (NOW HIRING)

Cogent Scientific

Expert Pharma Biochemist

Louisville, CO

$40K - $54K/yr

  • Medical

  • Dental

  • Vision

  • Retirement

  • PTO

Preparing and optimizing samples for single-particle cryo-electron microscopy (cryo-EM): complex ... PhD in Biochemistry, Molecular Biology, Structural Biology, Biophysics, or related field. * Hands ...

Cogent Scientific

Expert Pharma Biochemist

Louisville, CO · On-site

$115K - $125K/yr

  • Medical

  • Dental

  • Vision

  • Retirement

  • PTO

Preparing and optimizing samples for single-particle cryo-electron microscopy (cryo-EM): complex ... PhD in Biochemistry, Molecular Biology, Structural Biology, Biophysics, or related field. * Hands ...

University of Colorado

Post-Doctoral Fellow

Aurora, CO

$49K - $67K/yr

By employing high-resolution cryo-electron microscopy (cryo-EM) and tomography (cryo-ET), we aim to ... PhD or equivalent doctoral degree in Membrane biology, Structural Biology, Biochemistry, or a ...

Buck Institute

Postdoctoral Researcher - Zhou Lab

Novato, CA · On-site

$73K - $81K/yr

  • Medical

  • Dental

  • Vision

  • Retirement

  • PTO

... cryo-electron microscopy, and cryo-electron tomography. Applicants are not expected to have ... PhD completed by the start date in molecular cell biology, biochemistry, structural biology ...

Uw

Research Scientist/Engr 4

Seattle, WA

$122K/yr

Single particle cryo-electron microscopy and X-ray crystallization of viral glycoproteins, immunogen design, virology, biochemistry and biophysics. Purpose of the Research Project(s): The goal of our ...

University of Colorado

Post-Doctoral Fellow

Aurora, CO · On-site

$49K - $67K/yr

... as cryo-electron microscopy, tomography, kinetic assays, and computational analysis. Day-to-day ... Applicants must meet minimum qualifications at the time of hire. • PhD or equivalent doctoral ...

University of Colorado

Post-Doctoral Fellow

Aurora, CO · On-site

$49K - $67K/yr

By employing high-resolution cryo-electron microscopy (cryo-EM) and tomography (cryo-ET), we aim to ... PhD or equivalent doctoral degree in Membrane biology, Structural Biology, Biochemistry, or a ...

University of Colorado

Post-Doctoral Fellow

Aurora, CO

$49K - $67K/yr

PhD or equivalent doctoral degree in Structural Biology, Virology, or a closely related field ... Expertise in cryo-electron microscopy (cryo-EM), cryo-electron tomography (cryo-ET), Tomography, or ...

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Phd Cryo Electron Microscopy information

What is the difference between Phd Cryo Electron Microscopy vs Phd Structural Biology?

AspectPhd Cryo Electron MicroscopyPhd Structural Biology
Required CredentialsPhD in relevant field, microscopy expertisePhD in biology, biochemistry, or related field
Work EnvironmentLaboratories with advanced microscopy equipmentResearch labs, academic institutions, biotech companies
Industry UsageUsed for high-resolution imaging of biomoleculesUsed for understanding biological structures and functions
Common Search/ComparisonOften compared for research focus and techniquesBroader biological context

While both roles require advanced degrees and involve biological research, Phd Cryo Electron Microscopy specializes in imaging techniques to visualize biomolecules at near-atomic resolution. Phd Structural Biology encompasses a broader understanding of biological structures, often integrating various methods including cryo-EM. The choice depends on whether the focus is on imaging technology or biological function analysis.

What are the key skills and qualifications needed to thrive as a PhD cryo electron microscopy specialist?

To thrive as a PhD Cryo Electron Microscopy (Cryo-EM) specialist, you need a strong background in structural biology, biochemistry, and physics, typically supported by a doctoral degree in a related field. Expertise in operating advanced cryo-EM instruments, image processing software (such as RELION or CryoSPARC), and familiarity with data analysis pipelines is essential. Attention to detail, problem-solving ability, and effective collaboration skills help you excel when troubleshooting experiments and working within multidisciplinary teams. These competencies are crucial for generating high-quality structural data and advancing scientific discoveries in molecular biology.

What are some common challenges faced by PhD researchers specializing in cryo electron microscopy, and how can they be addressed?

PhD researchers in Cryo Electron Microscopy (Cryo-EM) often encounter challenges such as sample preparation issues, data collection bottlenecks, and interpreting complex datasets. Achieving optimal sample vitrification and minimizing beam-induced motion are technical hurdles that require patience and meticulous technique. Collaborating closely with experienced microscopists, leveraging advanced image processing software, and participating in specialized training workshops can greatly assist in overcoming these obstacles. Additionally, working in multidisciplinary teams fosters knowledge sharing and accelerates problem-solving, making it easier to advance high-impact structural biology projects.

What is a PhD in cryo electron microscopy?

A PhD in Cryo-Electron Microscopy (Cryo-EM) is a doctoral program focused on using advanced electron microscopy techniques to study the structures of biological molecules at near-atomic resolution. Students in this field develop expertise in sample preparation, imaging, and data analysis to better understand the form and function of proteins, viruses, and other complex biomolecules. Graduates often contribute to scientific research in fields such as structural biology, biochemistry, and drug discovery.
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Infographic showing various Phd Cryo Electron Microscopy job openings in the United States as of August 2026, with employment types broken down into 100% Full Time. Highlights an 100% In-person job distribution.

Postdoctoral Scholar

Oregon Health & Science University

Portland, OR • On-site

$70K - $86K/yr

Full-time

Re-posted 24 days ago

Oregon Health & Science University rating

8.1

Company rating: 8.1 out of 10

Based on 95 frontline employees who took The Breakroom Quiz

162nd of 618 rated colleges and universities

Job description

Department Overview
The Vollum Institute is a privately endowed research institute at Oregon Health & Science University dedicated to basic research that will lead to new treatments for neurological and psychiatric diseases. Vollum scientists have broad-ranging interests that coalesce around molecular neurobiology and cellular physiology. Their work has transformed the field of neuroscience and, in particular, have provided important advances in the study of synaptic transmission, neuronal development, neurotransmitter transporters, ion channels and the neurobiology of disease.
Function/Duties of Position
This position is full-time and the responsibilities are to conduct research exploring the structural and biophysical mechanisms of synaptic transmission by elucidating the structures of native neurotransmitter receptors or transporters, and their synapses, or elements of the auditory transduction complex, by single particle cryo-electron microscopy (cryo-EM) and cryo-electron tomography (cryo-ET) studies, in combination with complementary biochemical experiments.
  • Planning, executing, and analyzing experiments for independent research project(s) using biochemical methods and single particle and tomographic cryo-EM methods to elucidate the structure(s) of the target molecule(s) and their organization.
  • Manuscript preparation for individual projects and assisting other lab members with manuscripts as needed.
  • Assisting the PI and other lab members with grant application (data acquisition, writing assistance, editing) as needed.
  • Traveling to national and international meetings to present on findings.
  • Helping to mentor and train junior members of the laboratory.
  • Other duties as assigned.

Required Qualifications
  • PhD in biochemistry and biophysics.
  • Structural studies of biological molecules using cryo-EM, x-ray crystallography or NMR, in addition to complimentary biochemical studies.
  • Knowledge of cryo-EM, x-ray crystallography, Linux or UNIX computer language, theories and practice, as well as skills related to recombinant DNA technology, protein expression and purification, and basic biochemical analysis, including SDS PAGE and protein chromatography.

Preferred Qualifications
  • In depth experience in single particle cryo-EM and experience with protein expression, purification and biochemical studies, as well as experience in writing manuscripts and preparing and giving presentations.
  • Substantial experience in the publication of own work, as first author, in peer-reviewed publications.
  • Knowledge and skills in the areas of electron microscopy, preparation of EM grids, use and knowledge of computer programs for single particle cryo-EM and knowledge of membrane protein expression and purification from mammalian, insect or bacterial cells, along with accompanying biochemical analysis.
  • Fluent English language skills for writing and speaking, as well as ability to draft manuscripts and prepare oral presentations.

Additional Details
Standard laboratory work, Monday - Friday, 9:00am - 5:00pm, flexible with some evenings/weekends as experiments demand.
Why apply to OHSU?
We are Oregon's only public academic health center.
In addition to caring for patients, we lead groundbreaking research. We also train the next generation of health care professionals. As Portland's largest employer, we give you opportunities to learn and advance in a system of hospitals and clinics across Oregon and Southwest Washington.
All are welcome.
OHSU welcomes people of all ages, ethnicities, genders, national origins, religions and sexual orientations. We are striving to build an anti-racist, multicultural institution and encourage people with diverse backgrounds to apply.
To request reasonable accommodation, contact askhr@ohsu.edu

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About Oregon Health & Science University

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Oregon Health & Science University (OHSU) is a distinguished institution under the industry of higher education and healthcare, specifically in the field of medical science. Based in Portland, Oregon, US, it maintains a reputation for promoting research, teaching, patient care, and outreach. Established in 1887, OHSU has continually sought to redefine the parameters of healthcare delivery and biomedical discovery through its expansive catalog of programs and initiatives. A galvanizing mission drives OHSU: to improve the health and quality of life for all Oregonians through excellence, innovation, and leadership in health care, education, and research.

Industry

Colleges, universities, and professional schools

Company size

10,000+ Employees

Headquarters location

Portland, OR, US

Year founded

1887

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