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Peptide Formulation Scientist Jobs (NOW HIRING)

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... and formulation issues (e.g., nuclease sensitivity in iSRNA, peptide oxidation/deamidation ... Present findings and scientific arguments in meetings and technical reports; communicate risk ...

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Peptide Formulation Scientist information

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How much do peptide formulation scientist jobs pay per hour?

As of Sep 13, 2026, the average hourly pay for peptide formulation scientist in the United States is $37.61, according to ZipRecruiter salary data. Most workers in this role earn between $25.24 and $43.51 per hour, depending on experience, location, and employer.

What is the difference between Peptide Formulation Scientist vs Peptide Chemist?

AspectPeptide Formulation ScientistPeptide Chemist
Required CredentialsBachelor's or Master's in Chemistry, Pharmaceutical Sciences, or related fieldBachelor's or Master's in Chemistry, Biochemistry, or related field
Work EnvironmentLaboratories focused on formulation development and stability testingResearch labs conducting chemical synthesis and analysis
Employer & Industry UsagePharmaceutical and biotech companies developing peptide-based drugsResearch institutions and pharmaceutical companies involved in peptide synthesis
Common Search & Comparison IntentUnderstanding roles in formulation developmentUnderstanding chemical synthesis and analysis of peptides

The Peptide Formulation Scientist primarily focuses on developing and optimizing peptide drug formulations, ensuring stability and delivery. In contrast, the Peptide Chemist specializes in synthesizing and analyzing peptides at the chemical level. Both roles require strong chemistry backgrounds and are integral to peptide research and development in pharmaceutical settings.

What are popular job titles related to Peptide Formulation Scientist jobs?

For Peptide Formulation Scientist jobs, the most frequently searched job titles are:

Infographic showing various Peptide Formulation Scientist job openings in the United States as of September 2026, with employment types broken down into 4% Internship, 2% As Needed, 87% Full Time, 4% Part Time, and 3% Contract. Highlights an 85% Physical, 2% Hybrid, and 13% Remote job distribution, with an average salary of $78,236 per year, or $37.6 per hour.

Principal Scientist, Formulation & Drug Product Development

South San Francisco, CA โ€ข On-site

Denali Therapeutics
Scientific Research and Development Servicesย โ€ขย 201 - 500 employees

$159K - $207K/yr

Full-time

Medical, Retirement

Posted 3 days ago

New


Job description

We invite you to consider an opportunity with Denali to help achieve our goal of delivering meaningful therapeutics to patients.
We are seeking a Principal Scientist to join our Formulation & Drug Product Development team to serve as a formulation and drug product process development lead for our growing portfolio of protein biologics. This individual will provide technical formulation and drug product expertise for a broad range of novel large molecule protein biologics including Fc-enzyme fusion proteins, protein-oligonucleotide conjugates, and knob-in-hole multi-specifics across the development lifecycle. This role sits within the broader Large Molecule Analytical & Formulation/Drug Product process development group and is expected to partner closely with peers responsible for analytical development, bioprocess development, and quality team members.
Key Accountabilities / Core Responsibilities
  • Independently drive formulation and drug product development activities for one or more of Denali's large molecule biotherapeutics including:
    • Developing an understanding of key mechanisms of degradation for each potential therapeutic
    • Designing and executing appropriate formulation development studies to identify clinical and commercial formulation & dosage form, establish shelf life of DS & DP, assess in-use compatibility, and support comparability assessments.
    • Develop stress comparability strategies to support process changes and scale-up
    • Oversee drug product process development activities as well as DP process characterization and process validation activities to support clinical and commercial manufacturing
  • Hands-on biophysical and biochemical characterization of protein therapeutics in the laboratory using chromatography-, capillary-, spectroscopy-based analytical methods with a focus on evaluating product stability, compatibility, and comparability.
  • Translate understanding of critical quality attributes (CQA) and key mechanisms of degradation into robust, stable formulations and dosage forms that ensure product quality and efficacy.
  • Perform rigorous risk assessments of the impact of drug product manufacturing and storage conditions on product quality
  • Author technical documents including formulation development reports, ICH-compliant stability protocols, and relevant sections of regulatory filings to support external QC partners and regulatory submissions.
  • Oversee formulation and drug product manufacturing activities at external contract manufacturing organizations (CMO) including review of stability protocols, DP process development studies, tech transfer activities, review of drug product analytical control system specifications and DP-specific analytical method transfer and qualification protocols/reports.
  • Lead troubleshooting activities and serve as subject matter expert (SME) for Quality investigations at CMOs
  • Participate and be actively engaged in cross-functional technical decision-making including collaborating with Discovery Biotherapeutics, Bioprocess Development, Analytical Development and Quality
  • Contribute to establishing internal state-of-the-art formulation capabilities to support accelerated CMC development

Qualifications/Skills:
  • Typically a PhD in Chemical Engineering, Pharmaceutical Sciences, Biophysics, Analytical Chemistry,, or related scientific discipline and 10+ years of relevant industry experience in formulation and drug product development for protein therapeutics or BS/MS with commensurately greater directly relevant experience.
  • In-depth knowledge and extensive hands-on experience in developing a wide array of analytical protein characterization and biophysical methods (e.g. HPLC-based methods, cIEF, capillary electrophoresis, LC/MS, peptide mapping, spectrophotometry, SPR, light scattering, etc.)
  • Prior experience with high concentration liquid formulation development; prefilled syringe (PFS)/combination device process development; and/or process characterization/validation considered a strong plus.
  • Demonstrated track record of successfully developing biotherapeutic protein formulations as well as transferring and qualifying DP-related analytical methods at CMOs for protein therapeutic development programs including familiarity with applicable GMP requirements
  • Strong grasp of statistical approaches for data interpretation and analytical method development
  • Demonstrated ability to work effectively and collaboratively with other scientists on cross-functional projects teams as well as CMOs
  • Excellent critical thinking, scientific problem-solving, and organizational skills
  • Excellent oral and written communication skills
  • Motivated, detail-oriented, naturally curious individual with a creative approach to scientific problem solving and a positive outlook

Salary Range: $159,000.00 to $207,000.00 . Compensation for the role will depend on a number of factors, including a candidate's qualifications, skills, competencies, and experience. Denali offers a competitive total rewards package, which includes a 401k, healthcare coverage, ESPP and a broad range of other benefits. Learn more at https://www.denalitherapeutics.com/careers
This compensation and benefits information is based on Denali's good faith estimate as of the date of publication and may be modified in the future.
Denali is committed to its core company value of unity by creating a diverse and inclusive environment. We are proud to be an equal opportunity employer and do not discriminate against any employee or applicant for employment because of race, color, sex, age, national origin, religion, sexual orientation, gender identity and/or expression, status as a veteran, basis of disability, or any other federal, state, or local protected class.