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Overnight Lab Jobs in Chicago, IL (NOW HIRING)

Chemistry Lab Tech II

Aurora, IL

$18.75 - $25/hr

Maintain lab workspaces in a clean and organized manner at all times * Assisting with managing ... Overnight Travel may be required at the discretion of management * Regularly lift and/or move up to ...

Job Summary The Lab Assistant within the Media Department is responsible for preparing, sterilizing ... Overnight travel may be required at the discretion of management. * Must wear appropriate ...

Chemistry Lab Tech II

Aurora, IL · On-site

$20 - $22/hr

Maintain lab workspaces in a clean and organized manner at all times * Assisting with managing ... Overnight Travel may be required at the discretion of management * Regularly lift and/or move up to ...

Specialty: Cardiac Cath Lab * Discipline: RN * Start Date: 08/17/2026 * Duration: 13 weeks * 40 ... 5 overnight weekday call shifts per 4-week schedule * 30-minute response time required for call ...

Job Summary The Lab Assistant within the Media Department is responsible for preparing, sterilizing ... Overnight travel may be required at the discretion of management. * Must wear appropriate ...

Job Summary The Lab Assistant within the Media Department is responsible for preparing, sterilizing ... Overnight travel may be required at the discretion of management. * Must wear appropriate ...

RN - Overnight | St. Joseph Institute for Addiction | Port Matilda, Pennsylvania About the Job ... pertinent lab results, or change in medical status regarding response to medications, etc.

RN - Overnight | St. Joseph Institute for Addiction | Port Matilda, Pennsylvania About the Job: The ... Adjusts medications under provider's supervision as needed; monitors lab results to validate ...

Maintain lab workspaces in a clean and organized manner at all times * Assisting with managing ... Overnight Travel may be required at the discretion of management * Regularly lift and/or move up to ...

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Overnight Lab information

See Chicago, IL salary details

$9

$26

$46

How much do overnight lab jobs pay per hour?

As of Jul 30, 2026, the average hourly pay for overnight lab in Chicago, IL is $26.01, according to ZipRecruiter salary data. Most workers in this role earn between $19.81 and $28.70 per hour, depending on experience, location, and employer.

What are Overnight Lab jobs?

Overnight Lab jobs typically involve working during nighttime hours in laboratory settings. Employees may be responsible for processing samples, conducting experiments, analyzing data, or maintaining lab equipment while most daytime staff are not present. These roles are crucial for labs that operate 24/7, such as medical testing facilities, research institutions, or industrial labs, to ensure continuous workflow and timely results. Working overnight can involve unique challenges, including managing fatigue and adjusting to a non-traditional schedule, but it also often offers higher pay or shift differentials.

What is the difference between Overnight Lab vs Night Lab Technician?

AspectOvernight LabNight Lab Technician
CredentialsHigh school diploma or equivalent; some roles may require certification in lab proceduresHigh school diploma or equivalent; certification may be preferred
Work EnvironmentLaboratory setting, overnight shifts, often in healthcare or research labsLaboratory setting, overnight shifts, typically in healthcare or diagnostic labs
Employer & IndustryHospitals, diagnostic labs, research facilitiesHospitals, diagnostic labs, healthcare facilities
Common Search & ComparisonOvernight Lab vs Night Lab Technician

The main difference between an Overnight Lab and a Night Lab Technician lies in the job scope. An Overnight Lab often refers to the shift timing or the lab's operational hours, while a Night Lab Technician is a specific role responsible for performing lab tests during overnight shifts. Both roles typically require similar credentials and work in comparable environments, primarily in healthcare or research labs operating overnight hours.

What are some common challenges faced when working an overnight lab shift, and how can they be managed?

Overnight lab positions often require adapting to an unconventional sleep schedule, which can impact alertness and overall health. Managing fatigue is crucial; strategies include maintaining a consistent sleep routine, staying hydrated, and taking short, scheduled breaks during shifts. Communication with daytime staff is also important to ensure smooth handovers and continuity of work. Additionally, overnight staff may encounter limited on-site resources, so strong problem-solving skills and self-sufficiency are valuable in this role.

What are the key skills and qualifications needed to thrive as an Overnight Lab Technician, and why are they important?

To thrive as an Overnight Lab Technician, you need a solid understanding of laboratory procedures, safety protocols, and typically an associate degree or higher in a science-related field. Familiarity with lab instruments, data analysis software, and Laboratory Information Management Systems (LIMS) is often required. Attention to detail, effective time management, and strong problem-solving skills are crucial soft skills for this role. These competencies ensure accurate and timely results, maintain lab safety standards, and support continuous lab operations during overnight shifts.
What are the most commonly searched types of Lab jobs in Chicago, IL? The most popular types of Lab jobs in Chicago, IL are:
What cities near Chicago, IL are hiring for Overnight Lab jobs? Cities near Chicago, IL with the most Overnight Lab job openings:
Infographic showing various Overnight Lab job openings in Chicago, IL as of July 2026, with employment types broken down into 67% Full Time, and 33% Part Time. Highlights an 100% In-person job distribution, with an average salary of $54,099 per year, or $26 per hour.

Lead Med Lab Scientist II (Overnight)

Simple Laboratories

Chicago, IL

$40/hr

Full-time

Medical, Dental, Vision, Retirement, PTO

Posted yesterday

New


Job description

Simple Laboratories is looking for an Overnight Group Lead, Medical Laboratory Scientist, ASCP/AMT licensed individual who performs test procedures of moderate/high complexity at our Humboldt Park, Chicago laboratory location. The Lead, MLS is expected to demonstrate competency in all assays/instrument's cross sections [Generalist] including Blood Bank. Additionally, reporting to the Lab Manager providing team oversight and guidance as needed and serving as a technical resource for the department.
Shift Schedule: 11:00 PM to 7:30 AM with alternating weekends
ESSENTIAL JOB FUNCTIONS
• Demonstrate full proficiency in all duties of a Medical Lab Scientist
• Perform and report on assigned analytical tests in accordance with applicable Standard Operating Procedures (SOP) ensuring that applicable quality control requirements are met.
• Actively support and comply with laboratory policies and procedures for specimen handling and processing, test analysis, reporting and maintaining records of patient test results.
• Adhere to analytical schedules to maintain turnaround time of results including STATS or critical results to clients.
• Perform, review and document QC analysis to ensure accuracy of clinical data and proper instrument function. Make quality control decisions regarding the disposition of an assay or test.
• Review requests for validity checks and recommend an appropriate course of action in consideration of the limitations of specimen requirements and the effects of time and the quality of additional and/or repeat testing.
• Serve as a technical resource for the department by investigating and resolving analytical testing problems, recommending a course of action in instances identified as beyond acceptable limits, and responding to non-routine/complex inquiries and/or requests from clients and Business Development team.
• Assist Lab Manager by monitoring workflow to meet testing schedules; distributing and reviewing work assignments; training employees in laboratory techniques; resolving work-related problems of staff; and providing input for performance appraisals and disciplinary actions.
• Expedite the flow of work to maximize productive capacity by evaluating production systems and recommending enhancements and coordinating the resolution of production problems/issues involving other laboratory departments.
• Maintain laboratory areas and equipment in a safe, functional and sanitary condition.
• Complete training and competency checklists as appropriate and assist with the department’s annual competency testing process and documentation.
• Adheres to all established CLIA, HIPAA, OSHA, and laboratory safety requirements and reviews department activities to ensure compliance.
• Participate in government or regulatory agency inspections, as needed.
QUALIFICATIONS
  • Bachelor’s degree in Chemistry, Biology, Clinical Laboratory Sciences, or Medical Technology program from an accredited institution required.
  • Certificates/Licenses: MLS/MT (ASCP), AMT or another national accreditation required. Meets CLIA requirements for high complexity testing personnel.
Additionally, the position requires the following knowledge, skill and abilities:
• Comprehensive theoretical and operational job knowledge in designated specialty discipline.
• Proven leadership and problem-solving skills.
• Must be detail-oriented, can work independently, establish work priorities for self and other team members, to handle several tasks simultaneously for maximum laboratory efficiency.
• Ability to schedule and manage resources to meet department goals.
• Strong interpersonal skills to facilitate collaborative and cohesive relationships with internal and external customers and stakeholders.
• Strong communication skills are necessary to handle inquiries from internal and external customers, both verbal and written.
• Ability to deal with client information in a confidential manner.
• Proficiency in Microsoft Office (Word, Excel, Outlook, Teams) and company LIS.

BENEFITS
  • 401(k)
  • 401(k) Matching
  • Paid Time Off (PTO)
  • Health Insurance
  • Dental Insurance
  • Vision Insurance
  • STD/LTD
  • Hospital Indemnity Insurance
  • Critical Illness insurance
  • Accident Insurance
About Simple Laboratories
Simple Laboratories is a Chicago-based growing clinical laboratory, and we're driven to set a new standard in healthcare for patient care and customer support. This means developing the most efficient processes, monitoring operations and test results tirelessly and making our services accessible to patients. We have a dedicated and passionate team of lab technicians, phlebotomists, sales, IT and administrative staff and are looking for a candidate who can make an impact on the organization. Our employees are engaged, collaborative and team focused, while working together to provide the best service to our clients and patients.