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Operational Excellence Jobs in Worcester, MA (NOW HIRING)

AbbVie

Manager, Business Operational Excellence

Worcester, MA · On-site

$175K - $208K/yr

  • Medical

  • Dental

  • Vision

  • Retirement

  • PTO

Manager, Business Operational Excellence, AbbVie Bioresearch Center Inc., Worcester, MA (5 days a week on site). Key Responsibilities * Lead initiatives to reduce operating costs, enhance efficiency ...

AbbVie

Manager, Business Operational Excellence

Worcester, MA · On-site

$175K - $208K/yr

  • Medical

  • Dental

  • Vision

  • Retirement

  • PTO

Manager, Business Operational Excellence, AbbVie Bioresearch Center Inc., Worcester, MA (5 days a week on site). Key Responsibilities * Lead initiatives to reduce operating costs, enhance efficiency ...

AbbVie

Program Manager, Operations Excellence

Worcester, MA · On-site

$109K/yr

  • Medical

  • Dental

  • Vision

  • Retirement

  • PTO

Provide training and coaching to sponsors and Kaizen leaders, if needed Qualifications * 6-10 years experience in Operational Excellence roles * Bachelor's degree required; preferred disciplines:

Ulta Beauty, Inc.

Operations Manager

Bellingham, MA · On-site

  • Medical

  • Dental

  • Vision

  • Life

  • PTO

This position requires a passion for operational excellence, a drive for results, the ability to quickly and efficiently lead through unforeseen complexity, and the ability to lead, influence, and ...

Ulta Beauty, Inc.

Operations Manager

Bellingham, MA

  • Medical

  • Dental

  • Vision

  • Life

  • PTO

This position requires a passion for operational excellence, a drive for results, the ability to quickly and efficiently lead through unforeseen complexity, and the ability to lead, influence, and ...

Ulta Beauty

Operations Manager

Bellingham, MA · On-site

  • Medical

  • Dental

  • Vision

  • Life

  • PTO

This position requires a passion for operational excellence, a drive for results, the ability to quickly and efficiently lead through unforeseen complexity, and the ability to lead, influence, and ...

Fresenius Medical Care

Process Excellence Lead

Waltham, MA · On-site +1

$97K - $163K/yr

  • Medical

  • Dental

  • Vision

  • Retirement

  • PTO

Application Development & maintenance and Center of Excellence * Establish governance frameworks ... Ensure consistency across teams in delivery, tools, and operational practices * Maintain and ...

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Operational Excellence information

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How much do operational excellence jobs pay per hour?

As of Aug 14, 2026, the average hourly pay for operational excellence in Worcester, MA is $21.26, according to ZipRecruiter salary data. Most workers in this role earn between $16.78 and $24.23 per hour, depending on experience, location, and employer.

What types of projects or initiatives does someone in operational excellence typically lead or participate in?

Professionals in Operational Excellence are often involved in projects that focus on streamlining business processes, reducing waste, and increasing quality and efficiency across departments. Typical initiatives might include leading value stream mapping sessions, conducting root cause analyses, facilitating Kaizen events, and implementing new best practices or technologies to optimize workflow. These roles frequently require cross-functional collaboration with teams in production, quality, supply chain, finance, and IT to drive impactful change. Depending on the organization, you may also be responsible for training teams on process improvement methodologies and tracking the measurable results of these efforts.

What is an operational excellence role?

An operational excellence role involves improving business processes, increasing efficiency, and reducing waste within an organization. Professionals in this role often utilize methodologies like Lean, Six Sigma, or Kaizen and may hold certifications such as Lean Six Sigma Green Belt or Black Belt to drive continuous improvement initiatives.

What does an operational excellence professional do?

An Operational Excellence job focuses on improving business processes, efficiency, and overall performance by implementing best practices, data-driven decision-making, and continuous improvement methodologies like Lean or Six Sigma. Professionals in this role work to optimize workflows, reduce waste, and enhance productivity across various departments. They collaborate with leadership teams to drive a culture of continuous improvement and operational efficiency.

What are the key skills and qualifications needed for operational excellence?

To thrive in Operational Excellence, you need a solid understanding of process improvement methodologies (like Lean or Six Sigma), data analysis, and change management, often backed by relevant certifications such as Lean Six Sigma Green or Black Belt. Familiarity with analytical and process mapping tools like Microsoft Visio, Minitab, and ERP systems is highly beneficial. Exceptional communication, leadership, and problem-solving abilities are vital for driving cross-functional initiatives and engaging teams. These skills are crucial for identifying inefficiencies, implementing sustainable improvements, and fostering a culture of continuous improvement within an organization.

What skills are needed for operational excellence?

Operational excellence professionals need strong analytical skills, process improvement knowledge, and the ability to implement methodologies like Lean, Six Sigma, or Kaizen. Effective communication, problem-solving abilities, and proficiency with data analysis tools are also essential for driving continuous improvement and efficiency in organizations.

What are the most commonly searched types of Operational Excellence jobs in Worcester, MA?

The most popular types of Operational Excellence jobs in Worcester, MA are:

What job categories do people searching Operational Excellence jobs in Worcester, MA look for?

The top searched job categories for Operational Excellence jobs in Worcester, MA are:

Operational Excellence jobs near you
Infographic showing various Operational Excellence job openings in Worcester, MA as of August 2026, with employment types broken down into 85% Full Time, 13% Part Time, and 2% Contract. Highlights an 93% Physical, 3% Hybrid, and 4% Remote job distribution, with an average salary of $44,211 per year, or $21.3 per hour.

Director, PV Operational Excellence

Viridian Therapeutics, Inc.

Waltham, MA • On-site

$200K - $245K/yr

Full-time

Medical, Dental, Vision, Life, Retirement, PTO

Re-posted 18 days ago

Job description

Description
At Viridian, we are focused on developing best-in-class medicines for people living with autoimmune and rare diseases. Leveraging our team's expertise in antibody discovery and engineering, we have created a robust pipeline of differentiated investigational therapeutic candidates for well-validated targets.
Reporting to the Executive Director, PV Operations, the Director, PV Operational Excellence will be responsible for the quality oversight of the Pharmacovigilance activities throughout the products lifecycle, and will work closely with the department's leadership team, all departmental subfunctions, and cross-functionally to ensure all PV activities are conducted in compliance with regulatory requirements, Viridian Quality Management System, and established internal procedures. The Director, PV Operational Excellence will partner with area subject matter experts (SMEs) to ensure vendor oversight, appropriate governance and compliance monitoring and communication. The Director will strive to build and maintain a quality mindset across Pharmacovigilance and ensure ongoing inspection readiness.
This role is based in our Waltham, MA headquarters. Our office-based employees are required to work in the office three (3) days a week.
Responsibilities (including, but not limited to):
  • Develop the strategy for defining and implementing the applicable quality and compliance programs to ensure compliance across the global Viridian pharmacovigilance system
  • Lead the development of processes to effectively manage PV quality issues and CAPAs
  • Support the designs and implementation of a process for late case investigation
  • Lead the build, review and communication of key quality and compliance indicators across the PV system.
  • Collaborate with Pharmacovigilance and cross-functional leadership to ensure compliance with all aspects of the PV system
  • Lead inspection readiness activities at the function level to ensure ongoing readiness
  • Collaborate with Quality Assurance on PV regulatory intelligence activities
  • Collaborate with Quality Assurance on departmental training activities, including setting training requirements and training compliance for Pharmacovigilance
  • Provide dynamic leadership, strategic direction and global oversight of Pharmacovigilance quality initiatives
  • Elevate a quality mindset across Pharmacovigilance
  • Collaborate with QA Computerized Systems Validation and IT to provide oversight for outsourced hosted safety databases

Requirements
  • Requires 12+ years prior experience in pharmacovigilance
  • Advanced degree in a scientific discipline (e.g., PharmD, MD, PhD) preferred
  • Demonstrated knowledge of relevant FDA, EMA, International Conference on Harmonization (ICH) guidelines, initiatives, and regulations governing both Safety reporting and processing for clinical trial environments
  • Knowledge of MedDRA and WHO Drug Dictionary terminology and its application as well as experience with common safety database systems (Argus/ArisG/Veeva Safety)
  • Development and review of SOPs and Work Instructions
  • Vendor Management oversight responsibilities required. Experience with setting up a post-marketing PV vendor and global safety database preferred
  • Excellent organizational skills and demonstrated ability to navigate in a fast-paced environment with changing priorities
  • Excellent verbal and written communication skills including the ability to present to both internal and external partners
  • Strong analytical and problem-solving skills
  • Ability to work effectively in a fast-paced, dynamic environment
  • High integrity and commitment to patient safety
  • Strong commitment to ethical standards
  • Proficient with Microsoft Office suite (i.e., Word, PowerPoint, Excel, Outlook, SharePoint, etc.)
  • Ability to travel up to 10-15%
  • The salary range for this position is commensurate with experience

Viridian offers a comprehensive benefits package including:
• Competitive pay and stock options for all employees
• Medical, dental, and vision insurance
• 100% Paid Parental Leave
• Short- and long-term disability coverage
• Life, Travel and AD&D
• 401(k) Company Match with immediate company vest
• Employee Stock Purchase plan
• Generous vacation plan and paid company holiday shutdowns
• Various fertility, mental, financial, and proactive physical health programs
Viridian Therapeutics, Inc. provides equal employment opportunities to all employees and applicants for employment and prohibits discrimination, harassment, or retaliation of any type without regard to race, color, religion, age, sex, national origin, disability status, genetics, protected veteran status, sexual orientation, gender identity or expression, or any other characteristic protected by Federal, State, and Local laws. Viridian will ensure that individuals with disabilities are provided reasonable accommodation to participate in the job application or interview process, to perform essential job functions, and to receive other benefits and privileges of employment. Please contact us to request accommodation.
Viridian Therapeutics, Inc participates in E-Verify, the federal program for electronic verification of employment eligibility.

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