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Operational Excellence Project Manager Jobs in Raleigh, NC

MedPharm

Project Manager

Durham, NC · On-site

Project Manager Onsite | Durham, NC | Full-Time Position Summary - The Project Manager plays a ... Contribute to operational excellence by identifying efficiencies and best practices. * Ensure ...

MedPharm

Project Manager

Durham, NC · On-site

Project Manager Onsite | Durham, NC | Full-Time Position Summary - The Project Manager plays a ... Contribute to operational excellence by identifying efficiencies and best practices. * Ensure ...

MEDPHARM Corp

Project Manager

Durham, NC

Project Manager Onsite | Durham, NC | Full-Time Position Summary - The Project Manager plays a ... Contribute to operational excellence by identifying efficiencies and best practices. * Ensure ...

Pavion

Project Manager

Knightdale, NC · On-site

With a commitment to safety, reliability, and operational excellence, Pavion ensures scalable ... Technical Execution & Project Management- * Responsibilities focused on planning, coordinating, and ...

Pavion

Project Manager

Knightdale, NC · On-site

With a commitment to safety, reliability, and operational excellence, Pavion ensures scalable ... Technical Execution & Project Management- * Responsibilities focused on planning, coordinating, and ...

IQVIA

Senior Clinical Project Manager, CNS

Durham, NC · On-site

$93K - $232K/yr

You will leverage your expertise to lead complex, multi-regional studies and ensure operational excellence while building strong client relationships. Overview As a Senior Clinical Project Manager at ...

LHH US

Senior Project Manager

Chapel Hill, NC

$105K - $115K/yr

Drive continuous improvement initiatives focused on efficiency, cycle-time reduction, and operational excellence. * Support the implementation and enhancement of project management systems, tools ...

LHH US

Senior Project Manager

Chapel Hill, NC

$105K - $115K/yr

Drive continuous improvement initiatives focused on efficiency, cycle-time reduction, and operational excellence. * Support the implementation and enhancement of project management systems, tools ...

ReNuke Services

Project Controls Scheduler

New Hill, NC · On-site

$74.99/hr

This position typically is assigned to multiple Green I or Green II projects per the Project Management Center of Excellence Project Profile Matrix. Required Qualifications: Graduation from a two ...

Siemens Energy, Inc.

Project Manager

Raleigh, NC · On-site

A Snapshot of Your Day As a Project Manager, you will lead the execution of high-voltage AIS and ... Foster a safety-first culture while driving continuous improvement and operational excellence ...

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All JobsOperational Excellence Project JobsOperational Excellence Project Manager JobsOperational Excellence Project Manager Jobs in Raleigh, NC

Operational Excellence Project Manager information

See Raleigh, NC salary details

$37.9K

$93.1K

$149.2K

How much do operational excellence project manager jobs pay per year?

As of Aug 19, 2026, the average yearly pay for operational excellence project manager in Raleigh, NC is $93,076.00, according to ZipRecruiter salary data. Most workers in this role earn between $72,900.00 and $106,000.00 per year, depending on experience, location, and employer.

What does an operational excellence project manager do?

An Operational Excellence Project Manager is responsible for leading initiatives that improve efficiency, productivity, and quality within an organization. They use methodologies like Lean, Six Sigma, or Kaizen to identify areas for improvement and implement process changes. Their role often involves analyzing data, managing cross-functional teams, and ensuring that projects align with the company’s strategic goals. They help create a culture of continuous improvement and drive sustainable results across various departments.

How does an operational excellence project manager typically collaborate with cross-functional teams to implement process improvements?

Operational Excellence Project Managers regularly work with stakeholders from various departments such as operations, finance, IT, and quality assurance to identify inefficiencies and drive process improvements. This collaboration often involves facilitating workshops, leading Kaizen events, and aligning team members around common goals using methodologies like Lean or Six Sigma. Successful project managers build strong communication channels, ensure clear documentation, and foster a culture of continuous improvement so that all team members are engaged and accountable throughout the change process.

What are the key skills and qualifications needed to thrive as an operational excellence project manager, and why are they important?

To thrive as an Operational Excellence Project Manager, you need strong project management expertise, process improvement knowledge (such as Lean or Six Sigma), and a background in business or engineering. Familiarity with project management tools (e.g., MS Project, Asana), process mapping software, and certifications like PMP or Lean Six Sigma are often required. Exceptional communication, analytical thinking, and leadership skills help drive change and engage cross-functional teams. These competencies are critical for successfully executing initiatives that boost efficiency, reduce costs, and ensure sustainable organizational improvements.

What is the difference between Operational Excellence Project Manager vs Continuous Improvement Specialist?

AspectOperational Excellence Project ManagerContinuous Improvement Specialist
CertificationsLean, Six Sigma, PMPLean, Six Sigma, Kaizen
Work EnvironmentProject teams, cross-functional departmentsOperational teams, process improvement groups
Industry UsageManufacturing, healthcare, financeManufacturing, service industries, logistics

The Operational Excellence Project Manager oversees large-scale projects to improve efficiency and processes across departments, often managing multiple initiatives. The Continuous Improvement Specialist focuses on ongoing process enhancements within specific teams or areas, emphasizing incremental improvements. Both roles require Lean and Six Sigma certifications and work in similar industries, but their scope and responsibilities differ in scale and focus.

What cities near Raleigh, NC are hiring for Operational Excellence Project Manager jobs?

Cities near Raleigh, NC with the most Operational Excellence Project Manager job openings:

Operational Excellence Project Manager jobs near you
Infographic showing various Operational Excellence Project Manager job openings in Raleigh, NC as of August 2026, with employment types broken down into 1% As Needed, 82% Full Time, 15% Part Time, and 2% Contract. Highlights an 93% Physical, 2% Hybrid, and 5% Remote job distribution, with an average salary of $93,076 per year, or $44.7 per hour.

Senior Engineer Operational Excellence #4891

GRAIL

Durham, NC • On-site

$94K - $125K/yr

Other

Medical, Dental, Vision, Retirement, PTO

Posted 29 days ago

Job description

Our mission is to detect cancer early, when it can be cured. We are working to change the trajectory of cancer mortality and bring stakeholders together to adopt innovative, safe, and effective technologies that can transform cancer care.
We are a healthcare company, pioneering new technologies to advance early cancer detection. We have built a multi-disciplinary organization of scientists, engineers, and physicians and we are using the power of next-generation sequencing (NGS), population-scale clinical studies, and state-of-the-art computer science and data science to overcome one of medicine's greatest challenges.
GRAIL is headquartered in the bay area of California, with locations in Washington, D.C., North Carolina, and the United Kingdom. It is supported by leading global investors and pharmaceutical, technology, and healthcare companies.
For more information, please visit grail.com
The Senior Engineer, Operational Excellence will support continuous improvement initiatives within our sequencing-based cancer screening operations. This role will work at the intersection of data, process, and operations to enhance efficiency, quality, and scalability across laboratory and operational workflows. The ideal candidate is detail-oriented, data-savvy, and experienced in Lean methodologies, with a strong inclination toward solving complex operational problems through structured analysis and experimentation.
This role works on-site full-time at our office located in Durham, NC
Responsibilities:
  • Operational Data & Reporting
    • Develop and maintain operational dashboards and visualizations to track performance across workflows
    • Support generation and automation of KPI reporting, ensuring data integrity and usability
    • Collaborate with stakeholders to refine metrics and improve visibility into operational performance
  • Process Analysis & Monitoring
    • Perform data exploration and statistical analysis to identify trends, variation, and potential process deviations
    • Apply Statistical Process Control (SPC) and Quality Control (QC) methods to monitor and improve process stability
    • Identify leading indicators of performance issues and recommend proactive interventions
  • Continuous Improvement Execution
    • Execute and support Lean initiatives, including 5S, Kaizen events, and Six Sigma projects
    • Conduct root cause analyses (e.g., 5 Whys, Fishbone) and implement corrective and preventive actions (CAPAs)
    • Partner with operations teams to pilot, measure, and scale process improvements
  • Issue Tracking & Prioritization Support
    • Capture and document operational issues, risks, and improvement opportunities
    • Maintain structured tracking systems (e.g., backlogs, ticketing tools) for visibility and accountability
    • Lead prioritization of improvement efforts in collaboration with cross-functional stakeholders
  • Cross-Functional Collaboration
    • Work closely with Operations, Engineering, Software, and Product teams to implement process improvements
    • Translate operational needs into clear requirements for technical teams
    • Provide feedback loops to ensure solutions effectively address root causes

Required Qualifications:
  • Bachelor's degree in Engineering, Life Sciences, Industrial Engineering, or related field
  • 6+ years of experience in process engineering, operations, or continuous improvement roles, ideally in biotech, diagnostics, or manufacturing
  • Working knowledge of Lean, Six Sigma, and Kaizen methodologies (certification a plus)
  • Experience with data analysis and visualization tools (e.g., Excel, SQL, Python, Tableau, Power BI)
  • Familiarity with SPC/QC tools and statistical analysis techniques
  • Strong problem-solving skills with attention to detail and data accuracy
  • Effective communicator with the ability to collaborate across teams
  • Experience in NGS, clinical laboratory operations, or diagnostics workflows
  • Familiarity with regulated environments (CLIA, CAP, FDA) preferred

Preferred Qualifications:
  • Strong problem-solving skills with attention to detail and data accuracy
  • Effective communicator with the ability to collaborate across teams

Physical Demands and Work Environment:
  • Work performed across office, production, and executive settings.
  • Exposure to manufacturing environments, including noise, chemicals, and production equipment.
  • Extended or flexible hours may be required to meet organizational goals.
  • Use of personal protective equipment (PPE), including safety glasses, gloves, and hearing protection, required in designated areas.

The expected, full-time, annual base pay scale for this position is $94K - $125K. Actual base pay will consider skills, experience, and location.
This role may be eligible for other forms of compensation, including an annual bonus and/or incentives, subject to the terms of the applicable plans and Company discretion. This range reflects a good-faith estimate of the range that the Company reasonably expects to pay for the position upon hire; the actual compensation offered may vary depending on factors such as the candidate's qualifications. Employees in this role are also eligible for GRAIL's comprehensive and competitive benefits package, offered in accordance with our applicable plans and policies. This package currently includes flexible time-off or vacation; a 401(k) retirement plan with employer match; medical, dental, and vision coverage; and carefully selected mindfulness programs.
GRAIL is an equal employment opportunity employer, and we are committed to building a workplace where every individual can thrive, contribute, and grow. All qualified applicants will receive consideration for employment without regard to race, color, religion, national origin, sex, gender, gender identity, sexual orientation, age, disability, status as a protected veteran, , or any other class or characteristic protected by applicable federal, state, and local laws. Additionally, GRAIL will consider for employment qualified applicants with arrest and conviction records in a manner consistent with applicable law and provide reasonable accommodations to qualified individuals with disabilities. Please contact us at [email protected] if you require an accommodation to apply for an open position.
GRAIL maintains a drug-free workplace. We welcome job-seekers from all backgrounds to join us!

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