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Operational Excellence Project Manager Jobs in Raleigh, NC

GRAIL

Engineer, Operational Excellence #4892

Durham, NC · On-site

$69K - $93K/yr

For more information, please visit grail.com The Engineer, Operational Excellence will support ... Execute and support Lean initiatives, including 5S, Kaizen events, and Six Sigma projects * Partner ...

UNC HEALTH

Operational Project Manager

Morrisville, NC · On-site

$38.55 - $55.43/hr

The HCS Operational Project Manager provides project management, governance, and operational support for portfolio management processes, executive decision-making, capacity planning, and cross ...

New

CAI

Operational Readiness Project Manager

Raleigh, NC · On-site

We provide program and project management, commissioning, qualification, validation, start-up, and other consulting services associated with operational readiness and operational excellence to FDA ...

CAI

Operational Readiness Project Manager

Raleigh, NC · On-site

$140K - $175K/yr

We provide program and project management, commissioning, qualification, validation, start-up, and other consulting services associated with operational readiness and operational excellence to FDA ...

CAI

Operational Readiness Project Manager

Raleigh, NC · On-site

We provide program and project management, commissioning, qualification, validation, start-up, and other consulting services associated with operational readiness and operational excellence to FDA ...

avalign

Enterprise Project Manager

Raleigh, NC · On-site +1

... operational excellence, business process improvements, manufacturing initiatives, quality programs, and other enterprise-wide initiatives. The Project Manager serves as an individual contributor ...

LINDSAY PRECAST MASTER

Project Manager

Franklinton, NC · On-site

... to operational excellence and customer satisfaction. Key Responsibilities * Lead concrete ... Manage RFIs, submittals, change orders, project documentation, and project closeout. * Identify ...

LINDSAY PRECAST MASTER

Project Manager

Franklinton, NC · On-site

... to operational excellence and customer satisfaction. Key Responsibilities * Lead concrete ... Manage RFIs, submittals, change orders, project documentation, and project closeout. * Identify ...

ABM Industries, Inc.

Project Manager

Raleigh, NC · On-site

The Project Manager serves as the primary point of contact for customers and is responsible for ... and operational excellence. Physical Requirements • Ability to travel as required to support ...

Novartis

Sr. Project Manager, Engineering

Durham, NC · On-site

$108K - $201K/yr

As a Sr. Project Manager, Engineering at Novartis, you will lead a complex portfolio of capital ... Drive operational excellence by capturing lessons learned and supporting continuous improvement ...

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All JobsOperational Excellence Project JobsOperational Excellence Project Manager JobsOperational Excellence Project Manager Jobs in Raleigh, NC

Operational Excellence Project Manager information

See Raleigh, NC salary details

$37.9K

$93.1K

$149.2K

How much do operational excellence project manager jobs pay per year?

As of Aug 19, 2026, the average yearly pay for operational excellence project manager in Raleigh, NC is $93,076.00, according to ZipRecruiter salary data. Most workers in this role earn between $72,900.00 and $106,000.00 per year, depending on experience, location, and employer.

What does an operational excellence project manager do?

An Operational Excellence Project Manager is responsible for leading initiatives that improve efficiency, productivity, and quality within an organization. They use methodologies like Lean, Six Sigma, or Kaizen to identify areas for improvement and implement process changes. Their role often involves analyzing data, managing cross-functional teams, and ensuring that projects align with the company’s strategic goals. They help create a culture of continuous improvement and drive sustainable results across various departments.

How does an operational excellence project manager typically collaborate with cross-functional teams to implement process improvements?

Operational Excellence Project Managers regularly work with stakeholders from various departments such as operations, finance, IT, and quality assurance to identify inefficiencies and drive process improvements. This collaboration often involves facilitating workshops, leading Kaizen events, and aligning team members around common goals using methodologies like Lean or Six Sigma. Successful project managers build strong communication channels, ensure clear documentation, and foster a culture of continuous improvement so that all team members are engaged and accountable throughout the change process.

What are the key skills and qualifications needed to thrive as an operational excellence project manager, and why are they important?

To thrive as an Operational Excellence Project Manager, you need strong project management expertise, process improvement knowledge (such as Lean or Six Sigma), and a background in business or engineering. Familiarity with project management tools (e.g., MS Project, Asana), process mapping software, and certifications like PMP or Lean Six Sigma are often required. Exceptional communication, analytical thinking, and leadership skills help drive change and engage cross-functional teams. These competencies are critical for successfully executing initiatives that boost efficiency, reduce costs, and ensure sustainable organizational improvements.

What is the difference between Operational Excellence Project Manager vs Continuous Improvement Specialist?

AspectOperational Excellence Project ManagerContinuous Improvement Specialist
CertificationsLean, Six Sigma, PMPLean, Six Sigma, Kaizen
Work EnvironmentProject teams, cross-functional departmentsOperational teams, process improvement groups
Industry UsageManufacturing, healthcare, financeManufacturing, service industries, logistics

The Operational Excellence Project Manager oversees large-scale projects to improve efficiency and processes across departments, often managing multiple initiatives. The Continuous Improvement Specialist focuses on ongoing process enhancements within specific teams or areas, emphasizing incremental improvements. Both roles require Lean and Six Sigma certifications and work in similar industries, but their scope and responsibilities differ in scale and focus.

What cities near Raleigh, NC are hiring for Operational Excellence Project Manager jobs?

Cities near Raleigh, NC with the most Operational Excellence Project Manager job openings:

Operational Excellence Project Manager jobs near you
Infographic showing various Operational Excellence Project Manager job openings in Raleigh, NC as of August 2026, with employment types broken down into 1% As Needed, 82% Full Time, 15% Part Time, and 2% Contract. Highlights an 93% Physical, 2% Hybrid, and 5% Remote job distribution, with an average salary of $93,076 per year, or $44.7 per hour.

Engineer, Operational Excellence #4892

GRAIL

Durham, NC • On-site

$69K - $93K/yr

Full-time

Medical, Dental, Vision, Retirement, PTO

Posted 29 days ago

Job description

Our mission is to detect cancer early, when it can be cured. We are working to change the trajectory of cancer mortality and bring stakeholders together to adopt innovative, safe, and effective technologies that can transform cancer care.
 
We are a healthcare company, pioneering new technologies to advance early cancer detection. We have built a multi-disciplinary organization of scientists, engineers, and physicians and we are using the power of next-generation sequencing (NGS), population-scale clinical studies, and state-of-the-art computer science and data science to overcome one of medicine's greatest challenges.
 
GRAIL is headquartered in the bay area of California, with locations in Washington, D.C., North Carolina, and the United Kingdom. It is supported by leading global investors and pharmaceutical, technology, and healthcare companies.
 
For more information, please visit grail.com

The Engineer, Operational Excellence will support continuous improvement initiatives within our sequencing-based cancer screening operations. This role will work at the intersection of data, process, and operations to enhance efficiency, quality, and scalability across laboratory and operational workflows. The ideal candidate is detail-oriented, data-savvy, and experienced in Lean methodologies, with a strong inclination toward solving complex operational problems through structured analysis and experimentation.

This role works on-site full-time at our office located in Durham, NC

Responsibilities:

  • Operational Data & Reporting

    • Support generation and automation of KPI reporting, ensuring data integrity and usability

    • Collaborate with stakeholders to refine metrics and improve visibility into operational performance

  • Process Analysis & Monitoring

    • Perform data exploration and statistical analysis to identify trends, variation, and potential process deviations

    • Apply Statistical Process Control (SPC) and Quality Control (QC) methods to monitor and improve process stability

  • Continuous Improvement Execution

    • Execute and support Lean initiatives, including 5S, Kaizen events, and Six Sigma projects

    • Partner with operations teams to pilot, measure, and scale process improvements

  • Issue Tracking & Prioritization Support

    • Capture and document operational issues, risks, and improvement opportunities

    • Support prioritization of improvement efforts in collaboration with cross-functional stakeholders

  • Cross-Functional Collaboration

    • Work closely with Operations, Engineering, Software, and Product teams to implement process improvements

Required Qualifications:
  • Bachelor's degree in Engineering, Life Sciences, Industrial Engineering, or related field
  • 3+ years of experience in process engineering, operations, or continuous improvement roles, ideally in biotech, diagnostics, or manufacturing
  • Working knowledge of Lean, Six Sigma, and Kaizen methodologies (certification a plus)
  • Experience with data analysis and visualization tools (e.g., Excel, SQL, Python, Tableau, Power BI)
  • Familiarity with SPC/QC tools and statistical analysis techniques
  • Strong problem-solving skills with attention to detail and data accuracy
  • Effective communicator with the ability to collaborate across teams
Preferred Qualifications:
  • Strong problem-solving skills with attention to detail and data accuracy
  • Effective communicator with the ability to collaborate across teams
Physical Demands and Work Environment
  • Work performed across office, production, and executive settings.
  • Exposure to manufacturing environments, including noise, chemicals, and production equipment.
  • Extended or flexible hours may be required to meet organizational goals.
  • Use of personal protective equipment (PPE), including safety glasses, gloves, and hearing protection, required in designated areas.
The expected, full-time, annual base pay scale for this position is $69K - $93K.  Actual base pay will consider skills, experience, and location.

This role may be eligible for other forms of compensation, including an annual bonus and/or incentives, subject to the terms of the applicable plans and Company discretion. This range reflects a good-faith estimate of the range that the Company reasonably expects to pay for the position upon hire; the actual compensation offered may vary depending on factors such as the candidate's qualifications. Employees in this role are also eligible for GRAIL's comprehensive and competitive benefits package, offered in accordance with our applicable plans and policies. This package currently includes flexible time-off or vacation; a 401(k) retirement plan with employer match; medical, dental, and vision coverage; and carefully selected mindfulness programs.

GRAIL is an equal employment opportunity employer, and we are committed to building a workplace where every individual can thrive, contribute, and grow. All qualified applicants will receive consideration for employment without regard to race, color, religion, national origin, sex, gender, gender identity, sexual orientation, age, disability, status as a protected veteran, , or any other class or characteristic protected by applicable federal, state, and local laws. Additionally, GRAIL will consider for employment qualified applicants with arrest and conviction records in a manner consistent with applicable law and provide reasonable accommodations to qualified individuals with disabilities. Please contact us at [email protected] if you require an accommodation to apply for an open position.

GRAIL maintains a drug-free workplace. We welcome job-seekers from all backgrounds to join us!

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