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Nucleic Acid Jobs (NOW HIRING)

Scientist

San Diego, CA · On-site

$43 - $45/hr

Assess nucleic acid expression through molecular methods like qPCR, reporter assays and Western blotting. Maintenance of detailed electronic laboratory notebooks (ELN) and preparation of summary ...

Ideal candidates should have a strong background in molecular biology techniques and experience with nucleic acid production and analysis. Responsibilities • Independently execute high-throughput ...

Ideal candidates should have a strong background in molecular biology techniques and experience with nucleic acid production and analysis. Responsibilities • Independently execute high-throughput ...

Scientist

Durham, NC · On-site

$51/hr

This position focuses on method transfers, qualifications, validations, and stability testing, ensuring robust and compliant nucleic acid and cell-based assays in a fast-growing, startup CDMO ...

Ideal candidates should have a strong background in molecular biology techniques and experience with nucleic acid production and analysis. Responsibilities • Independently execute high-throughput ...

Strong underlying scientific knowledge of nucleic acid extraction, PCR, NGS library preparation, and hybrid capture technologies * Hands-on experience in reagent preparation and quality control for ...

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Nucleic Acid information

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$66.5K

$110.5K

$164.5K

How much do nucleic acid jobs pay per year?

As of Jul 9, 2026, the average yearly pay for nucleic acid in the United States is $110,545.00, according to ZipRecruiter salary data. Most workers in this role earn between $91,500.00 and $125,000.00 per year, depending on experience, location, and employer.

What are some common challenges faced by scientists working with nucleic acids in a laboratory setting?

Scientists working with nucleic acids often encounter challenges such as sample degradation, contamination, and maintaining RNase- and DNase-free environments. Precise pipetting and careful handling are critical, as even minor errors can impact the integrity and yield of nucleic acids. Collaboration with team members for troubleshooting, sharing best practices, and optimizing protocols is essential for overcoming these hurdles and ensuring successful experimental outcomes.

What are the key skills and qualifications needed to thrive as a Nucleic Acid Scientist, and why are they important?

To thrive as a Nucleic Acid Scientist, you need expertise in molecular biology, nucleic acid extraction, and quantitative analysis, typically backed by an advanced degree in biology, biochemistry, or a related field. Familiarity with PCR, qPCR, electrophoresis, and bioinformatics tools is crucial in this role. Strong analytical thinking, attention to detail, and effective teamwork skills help ensure robust experimental design and data interpretation. These abilities are vital to advance research, ensure data accuracy, and contribute meaningfully to scientific discovery and biotechnology innovation.

What is the job of the nucleic acid in the body?

Nucleic acids, such as DNA and RNA, are essential for storing and transmitting genetic information in the body. They direct cell activities by coding for proteins and are involved in processes like replication and protein synthesis, which are fundamental to growth and development.

What careers involve working with DNA?

Careers involving working with DNA include roles such as molecular biologist, geneticist, bioinformatician, and laboratory technician. These jobs typically require skills in laboratory techniques, DNA analysis, and often a background in biology, genetics, or biochemistry. Professionals in these fields work in research labs, healthcare, biotechnology, and pharmaceutical industries.

What are nucleic acid professionals and what do they do?

Nucleic acid professionals are scientists or technicians who specialize in the study and manipulation of nucleic acids, such as DNA and RNA. Their work often involves extracting, analyzing, synthesizing, or modifying these molecules for research, diagnostics, or therapeutic purposes. They may work in fields like molecular biology, genetics, biotechnology, or medical diagnostics, using techniques like PCR, sequencing, or gene editing. Their expertise is crucial for understanding genetic information, developing new medical treatments, and advancing scientific research.

What are the jobs of nucleic acids?

Nucleic acid jobs involve storing and transmitting genetic information in cells, primarily through DNA and RNA. Professionals working with nucleic acids may perform tasks such as sequencing, analysis, and research to understand genetic functions, often using laboratory techniques and specialized equipment. These roles are common in biotechnology, medical research, and molecular biology laboratories.

What biology jobs pay over $100k?

In the field of nucleic acid research, roles such as senior molecular biologist, biotech research director, and bioinformatics scientist often have salaries exceeding $100,000 annually. These positions typically require advanced degrees, specialized skills in laboratory techniques or data analysis, and experience in research or industry settings.

What is the difference between Nucleic Acid vs Molecular Biologist?

AspectNucleic AcidMolecular Biologist
Required CredentialsLaboratory training, molecular biology certificationsAdvanced degrees (BSc, MSc, PhD) in biology or related fields
Work EnvironmentResearch labs, biotech companies, healthcare settingsResearch institutions, universities, biotech firms
Industry UsageFocuses on nucleic acid extraction, analysis, and manipulationStudies genetic mechanisms, gene expression, and molecular processes

While Nucleic Acid specialists focus on working with DNA and RNA molecules, Molecular Biologists study broader genetic and molecular mechanisms. Both roles often overlap in research settings, but Nucleic Acid professionals typically specialize in laboratory techniques related to nucleic acids, whereas Molecular Biologists may engage in more comprehensive genetic research and analysis.

What cities are hiring for Nucleic Acid jobs? Cities with the most Nucleic Acid job openings:
What are the most commonly searched types of Nucleic Acid jobs? The most popular types of Nucleic Acid jobs are:
What states have the most Nucleic Acid jobs? States with the most job openings for Nucleic Acid jobs include:
Infographic showing various Nucleic Acid job openings in the United States as of July 2026, with employment types broken down into 3% As Needed, 68% Full Time, 25% Part Time, 1% Temporary, 2% Contract, and 1% Nights. Highlights an 79% Physical, and 21% Remote job distribution, with an average salary of $110,545 per year, or $53.1 per hour.

Scientist, LNP Process and Development

Serif Biomedicines, Inc.

Cambridge, MA • On-site

Other

Medical, Retirement

Posted 21 days ago


Job description

Company description

Serif Biomedicines is a privately held, early-stage biotechnology company pioneering Modified DNA as a new class of medicines. Modified DNA brings together the best features of mRNA and gene therapy, while mitigating their limitations, by enabling medicines that are durable, redosable, programmable, and scalable.  Serif was founded by Flagship Pioneering, an innovation enterprise that conceives, creates, resources, and grows first-in-category life sciences companies.

Flagship Pioneering has created over 100 groundbreaking companies over the past twenty years, all of which are pioneering novel and proprietary biological, industrial, and engineering approaches to solve major needs in human health and sustainability. These companies include Moderna (MRNA), Generate Biomedicines (GENB), Seres Therapeutics (MCRB), Tessera Therapeutics,  and Lila Sciences.

The role

We are seeking a highly motivated Scientist to support the development and scale-up of lipid nanoparticle (LNP) formulations for nucleic acid delivery. This role will focus on process optimization and scale-up of targeted LNPs encapsulating modified DNA and cofactor mRNA, while also contributing to research efforts aimed at improving LNP design and performance.

This is an ideal opportunity for a scientist with a strong background in process development who is interested in expanding into formulation development and early-stage R&D, including formulation screening and optimization of next-generation LNP systems.

The successful candidate will work collaboratively within cross-functional teams to advance LNP platform capabilities and support the development of scalable and robust nucleic acid delivery systems.

Key responsibilities

  • Support process development and optimization activities for LNP formulation and scale-up, including mixing parameters, encapsulation efficiency, and reproducibility.
  • Design and execute experiments to improve the performance and manufacturability of LNPs encapsulating modified DNA and mRNA.
  • Collaborate with internal and external teams to support characterization and evaluation of LNP formulations.
  • Assist with technology transfer and scale-up activities, including coordination with external partners or internal manufacturing teams.
  • Analyze and interpret experimental data, maintain accurate documentation, and communicate findings to project teams.
  • Stay current with advancements in LNP technologies and nucleic acid delivery approaches.

Professional experience and qualifications

  • PhD. in Chemical Engineering, Pharmaceutical Sciences, Bioengineering, or a related field, with 3+ years of relevant industry experience; M.S. with 8+ years of experience; or Bachelor with 10+ years of experience.
  • Strong background in process development, scale-up, or manufacturing of nanoparticle or LNP-based systems.
  • Experience working with nucleic acid formulations (e.g., mRNA, DNA) is highly preferred.
  • Familiarity with T mixing, or similar, formulation scale-up, and characterization techniques (e.g., DLS, encapsulation assays).
  • Demonstrated ability to design experiments, analyze data, and solve complex technical problems.
  • Strong communication and collaboration skills.

What We Offer

  • Opportunity to work at the forefront of LNP formulation innovation
  • Collaborative, science-driven culture with high impact research
  • Competitive compensation and benefits package

ABOUT FLAGSHIP PIONEERING

Flagship Pioneering invents and builds platform companies, each with the potential for multiple products that transform human health, sustainability and beyond. Since its launch in 2000, Flagship has originated more than 100 companies. Many of these companies have addressed humanity most urgent challenges: vaccinating billions of people against COVID-19, curing intractable diseases, improving human health, preempting illness, and feeding the world by improving the resiliency and sustainability of agriculture.

Flagship has been recognized twice on FORTUNE Change the World list, an annual ranking of companies that have made a positive social and environmental impact through activities that are part of their core business strategies and has been twice named to Fast Company annual list of the World Most Innovative Companies. Learn more about Flagship https://url.us.m.mimecastprotect.com/s/xLXBCqxk3LTk9pwcZf3CEkjif?domain=flagshippioneering.com.

At Flagship, we accept impossible missions to enable bigger leaps. Our core values guide us through uncertainty and toward lasting impact.

We are an equal opportunity employer. All qualified applicants will be considered for employment without regard to race, color, religion, sex, sexual orientation, gender identity, national origin, disability, protected veteran status, or any other characteristic protected by law.

Recruitment & Staffing Agencies: Flagship Pioneering and its affiliated Flagship Lab companies (collectively, "FSP") do not accept unsolicited resumes from any source other than candidates. The submission of unsolicited resumes by recruitment or staffing agencies to FSP or its employees is strictly prohibited unless contacted directly by Flagship Pioneering's internal Talent Acquisition team. Any resume submitted by an agency in the absence of a signed agreement will automatically become the property of FSP, and FSP will not owe any referral or other fees with respect thereto.

The salary range for this role is $100,000 - $143,000. Compensation for the role will depend on a number of factors, including a candidate's qualifications, skills, competencies, and experience. Serif Biomedicines currently offers healthcare coverage, annual incentive program, retirement benefits and a broad range of other benefits. Compensation and benefits information is based on Serif Biomedicines's good faith estimate as of the date of publication and may be modified in the future.