Bioinformatics Engineer
Rockville, MD · On-site
... Nextflow workflows for bulk RNA-seq, single-cell RNA-seq, DNA variant calling, methylation analysis, and emerging assay types • Architect scalable solutions capable of processing thousands of ...
Bioinformatics Engineer
Rockville, MD · On-site
... Nextflow workflows for bulk RNA-seq, single-cell RNA-seq, DNA variant calling, methylation analysis, and emerging assay types • Architect scalable solutions capable of processing thousands of ...
Bioinformatics Engineer
Rockville, MD · On-site
Develop, extend, and maintain Nextflow workflows for bulk RNA-seq, single-cell RNA-seq, DNA variant calling, methylation analysis, and emerging assay types * Architect scalable solutions capable of ...
Quick apply
Bioinformatics Engineer
Rockville, MD · On-site
Develop, extend, and maintain Nextflow workflows for bulk RNA-seq, single-cell RNA-seq, DNA variant calling, methylation analysis, and emerging assay types * Architect scalable solutions capable of ...
Bioinformatics Engineer
Rockville, MD · On-site
Develop, extend, and maintain Nextflow workflows for bulk RNA-seq, single-cell RNA-seq, DNA variant calling, methylation analysis, and emerging assay types * Architect scalable solutions capable of ...
Bioinformatics Engineer
Rockville, MD · On-site
Develop, extend, and maintain Nextflow workflows for bulk RNA-seq, single-cell RNA-seq, DNA variant calling, methylation analysis, and emerging assay types * Architect scalable solutions capable of ...
Develop, extend, and maintain Nextflow workflows for bulk RNA-seq, single-cell RNA-seq, DNA variant calling, methylation analysis, and emerging assay types * Architect scalable solutions capable of ...
Develop, extend, and maintain Nextflow workflows for bulk RNA-seq, single-cell RNA-seq, DNA variant calling, methylation analysis, and emerging assay types * Architect scalable solutions capable of ...
Familiarity with workflow orchestration tools (e.g., Nextflow, Snakemake, Airflow) * Experience transitioning research models into production-grade pipelines * Familiarity with CI/CD and ...
Familiarity with workflow orchestration tools (e.g., Nextflow, Snakemake, Airflow) * Experience transitioning research models into production-grade pipelines * Familiarity with CI/CD and ...
Staff Scientist
Bethesda, MD · On-site
Familiarity with workflow orchestration tools (e.g., Nextflow, Snakemake, Airflow) * Experience transitioning research models into production-grade pipelines * Familiarity with CI/CD and ...
Staff Scientist
Bethesda, MD · On-site
Familiarity with workflow orchestration tools (e.g., Nextflow, Snakemake, Airflow) * Experience transitioning research models into production-grade pipelines * Familiarity with CI/CD and ...
Postdoctoral Associate
$75K - $80K/yr
... Nextflow or Snakemake Licenses/ Certifications: N/A Additional Job Details The Patro lab is part of the University of Maryland Institute for Advanced Computer Studies (UMIACS). UMIACS is a ...
Postdoctoral Associate
$75K - $80K/yr
... Nextflow or Snakemake Licenses/ Certifications: N/A Additional Job Details The Patro lab is part of the University of Maryland Institute for Advanced Computer Studies (UMIACS). UMIACS is a ...
Bioinformatics Scientist
Bethesda, MD · On-site
Snakemake, Nextflow, CWL/WDL * Expertise building technical and user documentation for tools, pipelines, and applications * Experience building pipelines locally on-premise using available HPC ...
Bioinformatics Scientist
Bethesda, MD · On-site
Snakemake, Nextflow, CWL/WDL * Expertise building technical and user documentation for tools, pipelines, and applications * Experience building pipelines locally on-premise using available HPC ...
Bioinformatics Specialist
Washington, DC · On-site
$69K - $158K/yr
Experience using parallel programming capabilities through workflow tools, including Nextflow, on Linux-based high-performance computing environments * Experience with next-generation sequencing ...
Bioinformatics Specialist
Washington, DC · On-site
$69K - $158K/yr
Experience using parallel programming capabilities through workflow tools, including Nextflow, on Linux-based high-performance computing environments * Experience with next-generation sequencing ...
Postdoctoral Associate
College Park, MD · On-site
$75K - $80K/yr
... Nextflow or Snakemake Licenses/ Certifications: N/A Additional Job Details The Patro lab is part of the University of Maryland Institute for Advanced Computer Studies (UMIACS). UMIACS is a ...
Postdoctoral Associate
College Park, MD · On-site
$75K - $80K/yr
... Nextflow or Snakemake Licenses/ Certifications: N/A Additional Job Details The Patro lab is part of the University of Maryland Institute for Advanced Computer Studies (UMIACS). UMIACS is a ...
Snakemake, Nextflow, CWL/WDL * Expertise building technical and user documentation for tools, pipelines, and applications * Experience building pipelines locally on-premise using available HPC ...
Snakemake, Nextflow, CWL/WDL * Expertise building technical and user documentation for tools, pipelines, and applications * Experience building pipelines locally on-premise using available HPC ...
Associate Director of AI and Data
Rockville, MD · On-site
$60K - $60K/yr
Knowledge of the NIH STRIDES initiative and cloud economics is essential. • Mastery of big data technologies (Spark, Databricks) and workflow orchestration tools (Airflow, Nextflow, Cromwell). • ...
Associate Director of AI and Data
Rockville, MD · On-site
$60K - $60K/yr
Knowledge of the NIH STRIDES initiative and cloud economics is essential. • Mastery of big data technologies (Spark, Databricks) and workflow orchestration tools (Airflow, Nextflow, Cromwell). • ...
Snakemake, Nextflow, CWL/WDL * Expertise building technical and user documentation for tools, pipelines, and applications * Experience building pipelines locally on-premise using available HPC ...
Quick apply
Snakemake, Nextflow, CWL/WDL * Expertise building technical and user documentation for tools, pipelines, and applications * Experience building pipelines locally on-premise using available HPC ...
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Job description
Job Summary:
Axle is a bioscience and information technology company that offers advancements in translational research, biomedical informatics, and data science applications. They are seeking a Bioinformatics Engineer to join their team supporting major pharmaceutical clients, focusing on optimizing and integrating bioinformatics workflows for high-throughput sequencing analysis.
Responsibilities:
• Evaluate existing bioinformatics pipelines for performance, accuracy, and maintainability, identifying opportunities for optimization and enhancement
• Develop, extend, and maintain Nextflow workflows for bulk RNA-seq, single-cell RNA-seq, DNA variant calling, methylation analysis, and emerging assay types
• Architect scalable solutions capable of processing thousands of samples efficiently on Google Cloud Platform
• Optimize data input/output operations across pipeline modules to minimize bottlenecks and reduce computational costs
• Prepare and structure analysis outputs for visualization platforms and downstream statistical or machine learning applications
• Implement best practices for workflow versioning, containerization, testing, and documentation
• Collaborate with computational biologists, data scientists, and software engineers to integrate pipelines into broader analytical ecosystems
• Stay current with advances in sequencing technologies and analytical methods, evaluating and incorporating new tools as appropriate
Qualifications:
Required:
• Master's degree in bioinformatics, computational biology, computer science, or a related field (or equivalent experience)
• 3+ years of hands-on experience developing and maintaining bioinformatics pipelines in a production environment
• Proficiency with Nextflow (DSL2) and familiarity with workflow management concepts
• Strong experience with RNA-seq analysis (both bulk and single-cell) and DNA sequencing workflows (variant calling, methylation)
• Working knowledge of Google Cloud Platform services (Compute Engine, Cloud Storage, Batch, Life Sciences API, or similar)
• Proficiency in Python and/or R for scripting, data manipulation, and tool development
• Experience with containerization technologies (Docker, Singularity)
• Familiarity with version control systems (Git) and CI/CD practices
• Strong understanding of genomic file formats (FASTQ, BAM, VCF, BED) and common bioinformatics tools (STAR, Salmon, BWA, GATK, Bismark, Cell Ranger, Seurat, Scanpy)
Preferred:
• PhD in a relevant field
• Experience with nf-core pipelines and community standards
• Familiarity with workflow orchestration at scale (Cromwell, AWS Batch, or similar platforms)
• Experience optimizing cloud costs and resource utilization for large-scale genomics workloads
• Knowledge of data visualization tools and frameworks (e.g., R Shiny, Plotly, custom dashboards)
• Experience in pharmaceutical, biotech, or regulated research environments
• Familiarity with FAIR data principles and metadata standards
Company:
At Axle, we are driven by the mission to accelerate discovery and enhance organizational outcomes by revolutionizing operations with our innovative solutions. Founded in 2002, the company is headquartered in Rockville, USA, with a team of 501-1000 employees. The company is currently Late Stage.
Axle is a bioscience and information technology company that offers advancements in translational research, biomedical informatics, and data science applications. They are seeking a Bioinformatics Engineer to join their team supporting major pharmaceutical clients, focusing on optimizing and integrating bioinformatics workflows for high-throughput sequencing analysis.
Responsibilities:
• Evaluate existing bioinformatics pipelines for performance, accuracy, and maintainability, identifying opportunities for optimization and enhancement
• Develop, extend, and maintain Nextflow workflows for bulk RNA-seq, single-cell RNA-seq, DNA variant calling, methylation analysis, and emerging assay types
• Architect scalable solutions capable of processing thousands of samples efficiently on Google Cloud Platform
• Optimize data input/output operations across pipeline modules to minimize bottlenecks and reduce computational costs
• Prepare and structure analysis outputs for visualization platforms and downstream statistical or machine learning applications
• Implement best practices for workflow versioning, containerization, testing, and documentation
• Collaborate with computational biologists, data scientists, and software engineers to integrate pipelines into broader analytical ecosystems
• Stay current with advances in sequencing technologies and analytical methods, evaluating and incorporating new tools as appropriate
Qualifications:
Required:
• Master's degree in bioinformatics, computational biology, computer science, or a related field (or equivalent experience)
• 3+ years of hands-on experience developing and maintaining bioinformatics pipelines in a production environment
• Proficiency with Nextflow (DSL2) and familiarity with workflow management concepts
• Strong experience with RNA-seq analysis (both bulk and single-cell) and DNA sequencing workflows (variant calling, methylation)
• Working knowledge of Google Cloud Platform services (Compute Engine, Cloud Storage, Batch, Life Sciences API, or similar)
• Proficiency in Python and/or R for scripting, data manipulation, and tool development
• Experience with containerization technologies (Docker, Singularity)
• Familiarity with version control systems (Git) and CI/CD practices
• Strong understanding of genomic file formats (FASTQ, BAM, VCF, BED) and common bioinformatics tools (STAR, Salmon, BWA, GATK, Bismark, Cell Ranger, Seurat, Scanpy)
Preferred:
• PhD in a relevant field
• Experience with nf-core pipelines and community standards
• Familiarity with workflow orchestration at scale (Cromwell, AWS Batch, or similar platforms)
• Experience optimizing cloud costs and resource utilization for large-scale genomics workloads
• Knowledge of data visualization tools and frameworks (e.g., R Shiny, Plotly, custom dashboards)
• Experience in pharmaceutical, biotech, or regulated research environments
• Familiarity with FAIR data principles and metadata standards
Company:
At Axle, we are driven by the mission to accelerate discovery and enhance organizational outcomes by revolutionizing operations with our innovative solutions. Founded in 2002, the company is headquartered in Rockville, USA, with a team of 501-1000 employees. The company is currently Late Stage.