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Bioinformatics Pipeline Test Engineer - Healthcare - San Diego CA - Local to CA or who can relocate

Dallas, TX • On-site

Vytwo
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Other

Posted 18 days ago

Job description

Title: Bioinformatics Pipeline Test Engineer Domain: Healthcare Location: San Diego, CA - Local to CA or who can relocate Duration: 6 Months Experience: 2+ years

Must have
  • Bioinformatics OR Genomics
  • NGS OR "Next Generation Sequencing"
  • VCF OR BAM OR FASTQ
  • Python
  • Testing OR QA OR "Quality Engineer" OR Validation
  • Git
Job Description Role Overview

We are seeking a Bioinformatics Test Engineer to validate and ensure the quality of NGS data pipelines and bioinformatics workflows. The role requires a strong blend of bioinformatics knowledge, QA expertise, and automation skills.

Key Responsibilities
  • Design and execute testing strategies for NGS pipelines (alignment, variant calling, annotation)
  • Perform data validation, regression testing, and discrepancy analysis
  • Develop automated test scripts (Python)
  • Translate requirements into test cases and validation criteria
  • Work with CI/CD pipelines and cloud-based workflows
  • Collaborate with cross-functional teams to ensure data accuracy and reliability
Required Skills
  • Strong understanding of NGS workflows (FASTQ, BAM, VCF)
  • Experience in bioinformatics pipeline testing or QA
  • Proficiency in Python scripting
  • Hands-on with Git and CI/CD tools
  • Experience with cloud platforms (AWS/GCP/Azure) and data pipelines
  • Strong problem-solving and communication skills
Preferred
  • Experience in the biotech/life sciences domain
  • Familiarity with Nextflow, Snakemake, or similar workflows
  • Exposure to regulated environments (CLIA/FDA)
What We’re Looking For
  • Strong testing mindset + hands‑on engineering skills
  • Ability to debug pipelines and explain thought process clearly
  • Experience with real‑world data workflows (not just academic projects)
  • Mentions NGS pipelines + testing together
  • Has Python + Git + CI/CD
  • Mentions variant calling / VCF validation
  • Worked on cloud or production pipelines
Reject or deprioritize if:
  • Only academic bioinformatics (no testing/QA)
  • Only statistics validation (no system testing)
  • No Python or automation
  • No infra experience (cloud / CI/CD / DB)
  • Only local scripts, no real pipelines
Other High Priority Keywords
  • Variant Calling
  • Pipeline Testing
  • Regression Testing
  • Test Strategy OR Test Case Design
  • Data Validation
  • Golden Dataset OR Reference Dataset
  • CI/CD OR "GitHub Actions" OR GitLab OR "Azure DevOps"
  • AWS OR S3 OR Cloud
  • Nextflow OR Snakemake OR WDL OR Cromwell
  • Automation Testing
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