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Next Generation Sequencing Lab Supervisor Jobs (NOW HIRING)

Molecular Lab Supervisor

Chicago, IL · On-site

$60K - $80K/yr

MD + 1 year clinical lab experience * PhD (physical, chemical, or biological science) + 1 years ... Experience with next-generation sequencing * Experience supervising others * Work in a CLIA/CAP ...

... next-generation sequencing data with rapid turnaround times, including tumor genomic, germline ... lab; prefer experience with next-generation sequencing Ability to work with others to plan and ...

... next-generation sequencing data with rapid turnaround times, including tumor genomic, germline ... lab; prefer experience with next-generation sequencing • Ability to work with others to plan and ...

... next-generation sequencing data with rapid turnaround times, including tumor genomic, germline ... Must have experience working in a molecular lab; prefer experience with next-generation sequencing

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Next Generation Sequencing Lab Supervisor information

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$38.5K

$85.3K

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How much do next generation sequencing lab supervisor jobs pay per year?

As of Sep 8, 2026, the average yearly pay for next generation sequencing lab supervisor in the United States is $85,306.00, according to ZipRecruiter salary data. Most workers in this role earn between $68,000.00 and $100,000.00 per year, depending on experience, location, and employer.

What does a Next Generation Sequencing Lab Supervisor do?

A Next Generation Sequencing (NGS) Lab Supervisor oversees the daily operations of a laboratory that specializes in advanced DNA and RNA sequencing technologies. Their responsibilities include managing staff, ensuring the quality and accuracy of sequencing results, maintaining laboratory equipment, and implementing safety protocols. They also coordinate with researchers or clinicians to support projects, troubleshoot technical issues, and ensure compliance with regulatory standards. This role requires a strong background in molecular biology, hands-on experience with NGS platforms, and leadership skills.

What are the key skills and qualifications needed to thrive as a Next Generation Sequencing Lab Supervisor?

To thrive as a Next Generation Sequencing (NGS) Lab Supervisor, a strong background in molecular biology, NGS technologies, and laboratory management—often supported by an advanced degree in a life science field—is essential. Familiarity with sequencing platforms (such as Illumina or Ion Torrent), data analysis software, and compliance with regulatory standards (like CLIA or CAP) is typically required. Strong leadership, organizational skills, and the ability to communicate effectively with diverse teams set outstanding supervisors apart. These competencies ensure accurate results, efficient lab operations, and adherence to quality standards in a fast-evolving field.

What are some common challenges faced by a Next Generation Sequencing Lab Supervisor and how can they be addressed?

One common challenge for a Next Generation Sequencing (NGS) Lab Supervisor is balancing high-throughput workflow demands with strict quality control standards. Supervisors must ensure that the lab meets tight deadlines while maintaining data accuracy and adhering to regulatory guidelines. Additionally, managing a diverse team of technicians and scientists requires strong communication and leadership skills, especially when troubleshooting complex technical issues. Staying updated with evolving NGS technologies and protocols is essential, so continuous training and fostering a collaborative environment are key strategies for success.

What are popular job titles related to Next Generation Sequencing Lab Supervisor jobs?

For Next Generation Sequencing Lab Supervisor jobs, the most frequently searched job titles are:

Infographic showing various Next Generation Sequencing Lab Supervisor job openings in the United States as of August 2026, with employment types broken down into 1% As Needed, 79% Full Time, 13% Part Time, and 7% Contract. Highlights an 93% Physical, 2% Hybrid, and 5% Remote job distribution, with an average salary of $85,306 per year, or $41 per hour.

Next Generation Sequencing Lab Manager, GeneDx

Gaithersburg, MD • On-site

GeneDx, Inc
Health Care and Social Assistance • 11 - 50 employees

Full-time

Re-posted 5 days ago


GeneDx rating

9.3

Company rating: 9.3 out of 10

Based on 5 frontline employees who took The Breakroom Quiz

4th of 121 rated laboratories


Job description

Company Description



GeneDx,a division of BioReference Laboratories, is a rapidly-growing, diverse clinical laboratory in Gaithersburg, MD that provides molecular diagnosis for genetic disorders.


GeneDx is recruiting for a full-time Next Generation Sequencing Laboratory
Manager.





Job Description

Next Generation Sequencing Laboratory Manager



GeneDx, Inc



Gaithersburg MD






GeneDx is recruiting for a full-time Next Generation Sequencing Laboratory
Manager.





Manages the
administration of the daily operations of the NextGen Sequencing Lab that
conducts the testing of clinical DNA specimens for the purpose of diagnostic
genetic disease, using manual and automated methods in a team environment, and following established policies and procedures, in a professional manner.




Responsibilities





  1. Manages
    a group of testing personnel following established standard operating
    procedures for specimen handling and processing, test analysis, reporting of
    results to team leads, supervisors, and record-keeping.

  2. Ensures
    that all group members adhere to quality control policies and documents all
    quality control activities, instruments and procedural calibrations, reagent
    preparation and testing, and instrument maintenance performed.

  3. Identifies
    problems that may adversely affect test performance, takes authorized
    corrective action, and notifies key individuals.

  4. Oversees
    implementation of new protocols and QA/QC criteria and detects when test
    performance is not within acceptable levels. 
    Documents all corrective action.

  5. Maintains
    efficient lab operations and improves lab workflow and also contributes to
    reviewing and updating technical SOPs

  6. Always
    be able to document that proficiency testing is performed in the same manner as
    patient testing.

  7. Meets
    or exceeds target workload with high accuracy and attention to detail. 



















Qualifications




Education and Experience



Bachelor of Science degree in medical technology, chemistry, biology,
or related life science, and meets CLIA and New York State personnel standards
criteria, plus 5 years relevant work experience in molecular technology or
comparable skills and knowledge; or, Master of Science degree in a related
field, plus 2-3 years relevant experience; or, credentialed as a Molecular
Genetics technologist.




Additional Information

All your information will be kept confidential according to EEO guidelines.


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