ZipRecruiter

Log In

1

Multiplex Assay Development Jobs (NOW HIRING)

Veracyte

Senior Bioimage Scientist

San Diego, CA · On-site

$142K - $156K/yr

... stains, multiplex stains, spatial biology). * Buildimage analysis workflows to extract ... Proven expertise in tissue staining assays,IHC, imaging assay development, quantitative ...

Cell Signaling Technology

Scientist

Danvers, MA

Validate newly developed assays by analyzing experimental results, troubleshooting issues, and ... multiplex PCR. * Experience in qPCR experiments. This includes the use of different intercalating ...

next page

Showing results 1-20

People also search for

All JobsMultiplex Assay Development Jobs

Multiplex Assay Development information

See salary details

$21K

$93.3K

$180K

How much do multiplex assay development jobs pay per year?

As of Jun 7, 2026, the average yearly pay for multiplex assay development in the United States is $93,350.00, according to ZipRecruiter salary data. Most workers in this role earn between $72,500.00 and $103,000.00 per year, depending on experience, location, and employer.

What is multiplex assay development?

Multiplex assay development involves designing and optimizing laboratory tests that can simultaneously detect and measure multiple analytes—such as proteins, nucleic acids, or other molecules—in a single sample. These assays increase efficiency, save time, and reduce sample volume requirements compared to running separate tests for each target. Multiplex assays are widely used in clinical diagnostics, drug discovery, and research, allowing for comprehensive data collection and improved throughput. The development process includes selecting appropriate detection methods, validating performance, and ensuring the assay provides accurate and reproducible results.

What is the difference between Multiplex Assay Development vs Laboratory Scientist?

AspectMultiplex Assay DevelopmentLaboratory Scientist
CredentialsBachelor's or Master's in Life Sciences, specialized training in assay developmentBachelor's or higher in Life Sciences or related field
Work EnvironmentResearch labs focused on assay design and validationVaried labs, including clinical, research, or industrial settings
Industry UsagePrimarily in biotech, pharma, and diagnostics companiesBroadly in healthcare, research institutions, and industry

Multiplex Assay Development involves designing and optimizing multiple analyte tests, requiring specialized skills in assay chemistry and validation. Laboratory Scientists perform a wide range of experiments, including assays, but may not focus solely on multiplex assay creation. While both roles require strong laboratory skills, multiplex assay development is more specialized in assay design and validation for diagnostic or research purposes.

What are the key skills and qualifications needed to thrive in Multiplex Assay Development, and why are they important?

To excel in Multiplex Assay Development, you need a strong background in molecular biology, biochemistry, and assay design, often supported by an advanced degree in a life science field. Familiarity with technologies such as Luminex, ELISA, qPCR, and data analysis software, as well as experience following GLP/GMP standards, is essential. Attention to detail, problem-solving, and effective teamwork are crucial soft skills for optimizing protocols and troubleshooting complex experiments. These competencies ensure accurate, reliable assay results and drive innovation in biomarker discovery and diagnostics.

What are some common challenges faced when developing multiplex assays, and how can they be addressed?

One of the primary challenges in multiplex assay development is minimizing cross-reactivity and ensuring that individual assay components do not interfere with each other, which can affect sensitivity and specificity. Troubleshooting often involves careful selection of compatible antibodies, optimizing reagent concentrations, and rigorous validation using controls. Additionally, balancing assay complexity with ease of use and reproducibility requires strong collaboration with cross-functional teams, such as R&D and quality assurance, to refine protocols and ensure robust performance across samples. Staying updated on new technologies and best practices can also help overcome these hurdles effectively.
Infographic showing various Multiplex Assay Development job openings in the United States as of May 2026, with employment types broken down into 91% Full Time, and 9% Part Time. Highlights an 95% In-person, and 5% Remote job distribution, with an average salary of $93,350 per year, or $44.9 per hour.
Senior Scientist II - Translational Pathologist

Senior Scientist II - Translational Pathologist

MacroGenics, Inc.

Rockville, MD • On-site

$126K - $192K/yr

Full-time

Medical, Dental, Vision, Retirement, PTO

Posted 22 days ago

Job description

MacroGenics is a leader in the discovery and development of innovative medicines that utilize our next generation antibody-based technologies. Our team of 350+ dedicated individuals is advancing a pipeline of product candidates to treat patients with cancer. Our products and platforms have attracted multiple partnerships with leading pharmaceutical and biotechnology companies around the globe.
The Company considers its employees to be its most valuable asset and we are committed to providing opportunities for individuals to learn and grow as a means to further their professional development. MacroGenics' corporate culture promotes an atmosphere of innovation, open communication and teamwork where employees can see firsthand how they contribute to the success of the organization.
Summary of Position:
This position is not impacted by the business announcement issued on May 11, 2026 and will remain with MacroGenics. Please refer to the company press release for additional information: https://ir.macrogenics.com/news-releases/news-release-details/macrogenics-sell-gmp-manufacturing-operations-bora
The Senior Scientist II - Translational Pathologist will support tissue-based pathology activities across MacroGenics' antibody-drug conjugate (ADC) and immunotherapy programs from discovery through IND-enabling studies and early clinical development. This role is responsible for execution of day-to-day histopathologic and biomarker pathology activities, including slide review, assay support, digital pathology analysis, and coordination with external CROs.
The position will work closely with the Senior Director of Pathology and cross-functional team members to deliver high-quality pathology data that informs target selection, translational strategy, safety assessment, and development decisions. Scientific and regulatory accountability remains with senior pathology leadership.
Responsibilities and Job Duties
Preclinical & Translational Pathology
  • Perform necropsy and primary histopathologic assessment of tissues from in vivo pharmacology studies, including H&E, IHC, and multiplex immunofluorescence.
  • Conduct first-pass assessment of target expression, on-target/off-tumor findings, ADC payload-related tissue injury, and tumor-immune microenvironment features relevant to immunotherapy programs.
  • Prepare draft pathology interpretations, figures, and written summaries for internal review and program discussions.

Biomarker & Assay Support
  • Execute pathology components of translational biomarker strategies as defined by senior Pathology and Translational Medicine leadership.
  • Support development, optimization, and validation of single plex IHC and multiplex IHC and IF assays.
  • Perform tissue annotation and support development and optimization of digital pathology and image analysis algorithms under the guidance of the Senior Director of Pathology.
  • Contribute pathology data and figures to internal reports, study summaries, and regulatory-supporting documentation.
  • Coordinate biomarker assay development and validation with CROs.

Documentation & Data Stewardship
  • Draft pathology sections for study reports, slide decks, and internal presentations.
  • Maintain pathology image libraries, annotations, and reference materials.
  • Support development and maintenance of pathology-related SOPs, templates, and best practices.

Cross-Functional Collaboration
  • Present pathology findings in internal project team meetings.
  • Escalate and communicate complex findings, safety signals, or interpretation questions to the Translational Medicine leadership.

Minimum Qualifications
Education & Experience
  • MD, DVM, or PhD with formal training in pathology, histopathology, or a closely related discipline.
  • 3-5 years of experience in biomarker target validation, translational research, biotechnology, pharmaceutical, or CRO environments.

Skills & Abilities
  • Hands-on experience with histopathologic and immunohistochemical tissue evaluation.
  • Excellent pathology diagnostic skills.
  • Skilled in mIF development, validation and spatial analysis.
  • Experience with digital pathology and image analysis platforms (e.g., HALO, QuPath).
  • Strong scientific writing and communication skills.

Preferred Qualifications
  • MD/DVM strongly preferred.
  • Experience supporting ADC, immuno-oncology, or T-cell engager programs.
  • Experience working with AI/ML algorithms for digital pathology analysis.
  • Exposure to GLP toxicology studies and nonclinical safety assessments.
  • Experience working with external CROs.

Additional Information
The annual rate of pay for the Senior Scientist II position ranges from $126,200-192,500. This role is eligible for the Company's discretionary bonus and discretionary equity incentives. Eligible employees may participate in the Company's benefits programs, including medical / dental / vision / prescription coverage, employee wellness resources, 401(k) plan with employer match, access to an Employee Stock Purchase Plan, (ESPP), paid time off & paid parental leave benefits, and disability benefits.
The annual pay rate range is described in good faith, and the Company believes is the range of possible compensation for this role at the time of this posting depending on the candidate's experience, qualifications, geographic location, and other factors permitted by law. The Company may ultimately pay more or less than the posted range, and this range may be modified in the future. No amount is considered to be wages or compensation until such amount is earned, vested, and determinable under the terms and conditions of the applicable policies and plans. The amount and availability of any bonus, commission, benefits, or any other form of compensation and benefits that are allocable to a particular employee remains in the Company's sole discretion unless and until paid and may be modified at the Company's sole discretion, consistent with the law.
Statement
MacroGenics is proud to be an equal opportunity employer. Employment selection and related decisions are made without regard to race, color, national origin, sex, gender identity, sexual orientation, religion, age, disability, protected veteran status, or any other characteristic protected by federal, state or local law. We are committed to working with and providing reasonable accommodation to individuals with disabilities. If, because of a medical condition or disability, you need a reasonable accommodation for any part of the employment process, please email info@macrogenics.com or call (301) 354-3566 and/or 711 for TTD/TTY service.
Equal Opportunity Employer/Veterans/Disabled
We do not accept non-solicited resumes or candidate submittals from search/recruiting agencies.
Equal Opportunity Employer
This employer is required to notify all applicants of their rights pursuant to federal employment laws. For further information, please review the Know Your Rights notice from the Department of Labor.

Apply