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Agilent

Software Product Manager, LC/MS

Santa Clara, CA · On-site +1

$119K - $223K/yr

Conduct market and competitive research to identify opportunities and validate product direction * Act as a technical and workflow expert for your LC/MS products, supporting internal teams and ...

Jobtailor

Senior Counsel

Fresno, CA · On-site

$138K - $188K/yr

Provide leadership and direction to less experienced attorneys * Mentor junior attorneys * Deliver ... MS Outlook #J-18808-Ljbffr

MS Aerospace

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Machine Operator 2nd Shift

Sylmar, CA · On-site

$20 - $25/hr

Required Skills/Abilities: · Ability to follow directions and work well in a team. · Ability to interpret and translate engineering designs and documentation. · Thorough understanding of or the ...

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Scientist I - LC/MS (Bioanalytical)

San Diego, CA • On-site

BioAgilytix
Biotechnology Research and Development • 501 - 1,000 employees
Learn more about BioAgilytixexternal

$88K - $99K/yr

Full-time

Medical, Dental, Vision, Life, Retirement, PTO

Re-posted 19 days ago

Job description

At BioAgilytix, we are passionate about premier science and the impact it has on our world. Our team of highly experienced scientists and professionals deliver tailored services for supporting new medicine breakthroughs with best-in-class bioanalytical services. We are tirelessly committed to our customers by being solution-oriented and deadline-driven. . . and we are growing. Our culture is fast-paced, fun and never boring. Because we work across numerous clients and drug modalities, your career can develop rapidly. You'll gain experience with a variety of challenges all while you enable life-changing, life-saving therapeutics to the patients who need them.
We are seeking a Scientist I to join our LC/MS large molecule team, supporting bioanalytical studies for biologics, proteins, peptides, ADCs, and biomarkers. In this role, you will take ownership of assay development, validation, and sample analysis using advanced chromatographic and mass spectrometric techniques. You'll design and execute experiments, troubleshoot assays, analyze data, and prepare study documentation in alignment with GLP requirements. This is an excellent opportunity for a scientist with hands-on LC/MS experience who is looking to deepen their expertise in regulated bioanalysis and contribute directly to preclinical, clinical, and product release studies.
At our organization, we're dedicated to pushing the boundaries of analytical science. Our LC/MS team leverages the synergy between liquid chromatography (LC) and mass spectrometry (MS) to revolutionize how we understand and quantify compounds in complex samples. With a steadfast commitment to excellence and innovation, we tackle challenges across the spectrum of drug discovery to clinical diagnostics, driving advancements that shape the future of healthcare.
Essential Responsibilities
  • Lead the development, validation, and sample analysis of large molecules such as ADCs, monoclonal antibodies and other proteins, peptides, oligonucleotides, biomarkers, and small molecules using various techniques including chromatographic (LC-MS/MS) in support of preclinical and clinical PK/PD studies.
  • Plan and direct experimental design for junior staff
  • Drive bioanalytical projects to align with client timelines
  • Frequent communication with clients to discuss technical details and provide project updates.
  • Advise clients on PK/ADME assay best practices
  • Author documents (methods, SOPs, reports)
  • Statistical analysis of bioanalytical data
  • Review of documentation
  • Peer review raw data
  • Prepare reagents
  • Troubleshoot assays
  • Design assay runs independently
  • Responsible for prompt identification and notification of deviations
  • Write plans/reports for sample analysis
  • Order and keep accurate inventories of supplies for laboratory needs and forecast future needs based on projected project needs
  • Perform assays according to GLP guidance or SOPs

Additional Responsibilities
  • Other duties as needed

Minimum Preferred Qualifications: Skills
  • Ability to perform routine laboratory tasks accurately while following established methodologies, including sample preparation, operation and maintenance of standard laboratory equipment.
  • Experience with chromatographic assay development, validation, and execution for PK, PD (biomarker), ADME, and other small molecule assays.
  • Experience developing chromatographic assays using LC-MS/MS, HPLC, UPLC, and/or UPLC-HRMS, including protein binding, CYP inhibition, CYP induction, or CYP phenotyping assays.
  • Strong data analysis, statistical analysis, and data visualization skills.
  • Proficiency with Microsoft Office (Word, Excel) and scientific software such as Sciex OS/Analyst, MassLynx, Chromeleon, Watson LIMS, JMP, and GraphPad Prism.
  • Experience working in a regulated laboratory environment with knowledge of GxP principles, including GLP, GCLP, GCP, and Good Documentation Practices (GDP).
  • Strong experimental design, troubleshooting, and scientific problem-solving skills.
  • Ability to manage multiple priorities, work independently, and adapt to changing priorities while taking direction effectively.
  • Highly organized, detail-oriented, and able to meet deadlines in a fast-paced environment.
  • Strong verbal and written communication skills with the ability to collaborate effectively across cross-functional teams.
  • Demonstrated customer service mindset with a commitment to delivering high-quality results for internal and external stakeholders.

Minimum Preferred Qualifications: Education/Experience - Scientist I
  • Bachelor's degree in chemistry, biochemistry, biotechnology, biology, immunology, or related field with not less than six (6) years' experience in a scientific laboratory environment; or
  • Master's degree in chemistry, biochemistry, biotechnology, biology, immunology, or related field with not less than four (4) years' experience in a scientific laboratory environment; or
  • PhD in chemistry, biochemistry, biotechnology, biology, immunology, or related field with not less than two (2) years' experience in a scientific laboratory environment
  • Knowledge of regulatory guidance and industry best practices for PK, ADME, LC/MC/MC, and other small molecule assays is preferred

Supervision Received
  • Infrequent supervision and instructions
  • Frequently exercises discretionary authority

Working Environment
  • Primarily laboratory environment
  • Exposure to biological fluids with potential exposure to infectious organisms
  • Rare exposure to skin and lung irritants, toxic materials, and hazardous waste
  • Personal protective equipment required, such as protective eyewear, garments, and gloves
  • Routinely uses standard office equipment such as computers, phones, photocopiers, and filing cabinets

Physical Demands
  • Ability to work in an upright and/or stationary position for up to 8 hours per day
  • Repetitive hand movement of both hands with the ability to make fast, simple, repeated movements of the fingers, hands, and wrists to operate lab equipment
  • Frequent mobility needed
  • Frequent crouching, stooping, with frequent bending and twisting of upper body and neck
  • Light to moderate lifting and carrying (or otherwise moves) objects including laboratory equipment, laboratory supplies, and laptop computer with a maximum lift of 20 pounds
  • Ability to access and use a variety of computer software
  • Ability to communicate information and ideas so others will understand, with the ability to listen to and understand information and ideas presented through spoken words and sentences
  • Frequently interacts with others to obtain or relate information to diverse groups
  • Requires multiple periods of intense concentration
  • Performs a wide range of variable tasks as dictated by variable demands and changing conditions with little predictability as to the occurrence
  • Ability to perform under stress and multi-task
  • Regular and consistent attendance

Position Type and Expected Hours of Work
  • This is a full-time position
  • Some flexibility in hours is allowed, but the employee must be available during the "core" work hours as published in the BioAgilytix Employee Handbook
  • Occasional weekend, holiday, and evening work required
  • Occasional travel required

$88,000 - $99,000 a year
In alignment with our compensation philosophy and recruiting governance practices, the salary range for this role represents a good faith estimate of the base compensation for a fully qualified candidate. Individual offers are determined based on a comprehensive evaluation of each candidate's experience, technical expertise, scope alignment, and internal equity considerations, as well as market data and geographic factors where applicable. As a result, final compensation may fall within or outside of the posted range and will be determined in accordance with applicable state and local pay transparency laws.
BENEFITS AND OTHER PERKS
Medical Insurance (HDHP with HSA; PPO), Dental Insurance, Vision Insurance, Flexible Spending Account (medical; dependent care), Short Term Disability | Long Term Disability Life Insurance, Paid Time Off (4 weeks per year), Parental Leave, Paid Holidays (9 scheduled; 5 floating), 401k with Employer Match, Employee Referral Program
COMMITMENT TO EQUAL OPPORTUNITY
BioAgilytix provides equal employment opportunities to all employees and applicants for employment without regard to race, color, ancestry, national origin, gender, sexual orientation, marital status, religion, age, disability, gender identity, results of genetic testing, service in the military, or any other group protected by federal, state, or local law.
To learn more about how we collect, use, and protect your information, please review our Privacy Policy and Terms of Use.
We may use artificial intelligence (AI) tools to support parts of the hiring process, such as reviewing applications, analyzing resumes, or assessing responses and identifying potential inconsistencies or verification signals in application materials based on available information. These tools assist our recruitment team but do not replace human judgment. Final hiring decisions are ultimately made by humans. If you would like more information about how your data is processed, please contact us.

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