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What are the key skills and qualifications needed to thrive as a Microphysiological Systems Scientist, and why are they important?

To thrive as a Microphysiological Systems Scientist, you need a strong background in cell biology, tissue engineering, and biomaterials, typically supported by an advanced degree in biological sciences or bioengineering. Familiarity with microfluidic device fabrication, imaging systems, and analytical software like MATLAB or ImageJ is often required. Creative problem-solving, attention to detail, and strong collaboration skills are crucial in this interdisciplinary field. These skills enable the design and analysis of complex biological models that advance drug discovery and biomedical research.

What are microphysiological systems?

Microphysiological systems, also known as organ-on-a-chip technologies, are advanced laboratory models that replicate the functions of human organs on a miniature scale. These systems use living cells arranged on micro-engineered platforms to mimic the structure and function of tissues and organs. They are used in biomedical research to study disease mechanisms, drug responses, and toxicity in a controlled environment, potentially reducing the need for animal testing. Microphysiological systems provide more accurate and human-relevant data compared to traditional cell cultures or animal models.

What is the difference between Microphysiological vs Cell Culture Technician?

AspectMicrophysiologicalCell Culture Technician
Required CredentialsTypically requires a degree in biology, biomedical engineering, or related fieldsOften requires a degree or certification in biology or laboratory techniques
Work EnvironmentResearch labs, biotech companies, pharmaceutical testing facilitiesLaboratories, research institutions, biotech companies
Industry UsageUsed in drug testing, disease modeling, tissue engineeringUsed in cell growth, maintenance, and preparation for experiments

Microphysiological roles focus on creating complex tissue models that mimic human organs, often requiring advanced technical skills. Cell Culture Technicians primarily handle cell growth and maintenance. While both roles involve laboratory work and biological expertise, Microphysiological positions typically demand more specialized knowledge in tissue engineering and organ-on-chip systems.

What are some common challenges faced by microphysiological system researchers, and how can new team members prepare for them?

Microphysiological system researchers often encounter challenges such as integrating complex biological and engineering concepts, troubleshooting device malfunctions, and ensuring reproducibility of experimental results. New team members can prepare by staying updated on the latest advances in organ-on-chip technologies, refining their problem-solving skills, and actively communicating with multidisciplinary colleagues. Participating in regular team meetings and collaborating closely with engineers, biologists, and data analysts will help address issues as they arise and foster a supportive research environment.
What are popular job titles related to Microphysiological jobs in Ohio? For Microphysiological jobs in Ohio, the most frequently searched job titles are:
What job categories do people searching Microphysiological jobs in Ohio look for? The top searched job categories for Microphysiological jobs in Ohio are:
Microphysiological jobs near you
Postdoctoral Fellow - Chao Ma Lab

Postdoctoral Fellow - Chao Ma Lab

Cleveland Clinic

Cleveland, OH • On-site

$95K/yr

Other

Medical, Dental, Vision, Retirement

Re-posted 9 days ago

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Company rating: 7.2 out of 10

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Job description

Highly motivated individuals with a PhD or MD/PhD in relevant area are encouraged to apply. This training position, under the direct supervision of a Cleveland Clinic Principal Investigator will provide practical training and experience in a research setting. This position is appointed through Cleveland Clinic Research. The successful applicant will be able to demonstrate a commitment to research, a collaborative work ethic and strong communication skills, both written and verbal. This program is expected to be completed within 5 years. Compensation follows the NIH NRSA Postdoctoral Salary Scale based on total years of postdoctoral experience.

NIH NRSA Postdoctoral Salary Scale

Years of Experience: Stipend for FY 2026

0: $63,480
1: $63,900
2: $64,380
3: $66,948
4: $69,180
5: $71,748
6: $74,424
7 or More: $77,076

Principal Investigator: Chao Ma, PhD

Cleveland Clinic Research Department: Cancer Sciences

Lab Research Topics:

  • Organ-on-a-Chip, Microfluidics, Microphysiological system
  • Hematopoietic Biology and Hematological malignancies
  • Disease Modeling and Cancer Bioengineering
  • Stem cell Biology, Synthetic Biology, Systems biology, Spatial Omics
  • Biomedical/Mechanical/Tissue Engineering, 3D Printing

For more information about the lab's research, please visit: https://www.lerner.ccf.org/immunotherapy/ma/or contact Dr. Ma at mac7@ccf.org

Responsibilities:

  • Independent project design with the goal of data generation, analysis, interpretation and manuscript preparation
  • Publish research articles in high-impact journals and present research results in national and international scientific meetings.
  • Contribute to project development and collaboration, grant writing, progress reports, and papers.
  • Contribute to lab management, protocol development and maintenance, and mentoring of junior trainees.

Education:

  • PhD or MD/PhD required
  • MD with relevant laboratory experience may substitute for PhD

Languages:

  • English Proficiency proof required for candidates arriving on J-1, J-2, or F1 + OPT visa status

Work Experience:

  • Previous experience in a research or academic setting. Graduate student experience meets this requirement.
  • Scientific writing experience

Additional Preferred Qualities:

  • Excellent writing and communication skills, able to work independently and effectively with other members in a productive team.
  • Strong research expertise in molecular, cellular, or tissue engineering are preferred.
  • Strong research expertise in immunology, immune-oncology, or immune-engineering are preferred.
  • Strong research expertise in culture of stem cell or organoid are preferred.
  • Strong training background in biomedical engineering, microfabrication, bioprinting, lab-on-a-chip and microfluidics are preferred.

Physical Requirements:

  • Ability to perform work in a stationary position for extended periods
  • Ability to operate a computer and other office equipment
  • Ability to communicate and exchange accurate information
  • Ability to distinguish color
  • Manual dexterity to handle specimens and repair equipment
  • Ability to lift and transport equipment or specimens weighing up to 20 pounds
  • May be exposed to hazardous chemicals, bio-hazards, radioactive materials, etc.

Personal Protective Equipment:

  • PPE per institutional requirements; may vary by laboratory

Preferred Application Materials:

  • A cover letter summarizing past research experience and accomplishments
  • Current and future research interests
  • Career goals (2-page maximum)
  • Current CV with publications
  • Contact information of three references

All application materials should be submitted directly via email to Chao Ma at mac7@ccf.org

Keywords: Postdoc, Research, Cleveland Clinic Research, Center for Immunotherapy and Precision Immuno-Oncology (CITI), Cell therapy and immune-engineering program (CTIP), Biomedical engineering, Cancer Bioengineering, Disease Modeling, Immunotherapy, Microfluidics, Organ-on-a-Chip/Lab-on-a-Chip, Pluripotent stem cell, CAR T-cell therapy

Pay Range

Minimum Annual Salary: $31,200.00

Maximum Annual Salary: $95,000.00

The pay range displayed on this job posting reflects the anticipated range for new hires. A successful candidate's actual compensation will be determined after taking factors into consideration such as the candidate's work history, experience, skill set and education. The pay range displayed does not include any applicable pay practices (e.g., shift differentials, overtime, etc.). The pay range does not include the value of Cleveland Clinic's benefits package (e.g., healthcare, dental and vision benefits, retirement savings account contributions, etc.).

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