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Mes System Administrator Jobs (NOW HIRING)

peakenergy.com

About the Role - IT System Administrator Peak Energy is looking for a Sacramento-based IT System ... Support the boundary between corporate IT and operational technology (OT) systems -- MES, PLCs ...

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Mes System Administrator information

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$41K

$88.9K

$137.5K

How much do mes system administrator jobs pay per year?

As of Sep 9, 2026, the average yearly pay for mes system administrator in the United States is $88,927.00, according to ZipRecruiter salary data. Most workers in this role earn between $70,000.00 and $104,000.00 per year, depending on experience, location, and employer.

What is a MES System Administrator?

MES System Administrators are IT professionals responsible for managing, maintaining, and supporting Manufacturing Execution Systems (MES) within a production environment. They ensure the MES software is properly configured, updated, and integrated with other enterprise systems such as ERP and SCADA. Their role includes troubleshooting system issues, managing user access, maintaining data integrity, and ensuring system performance to support manufacturing operations. By overseeing the MES, they help ensure efficient production tracking, quality control, and real-time monitoring on the factory floor.

What skills and qualifications are needed to be a MES System Administrator?

To thrive as a MES System Administrator, you need a solid background in computer science, database management, and manufacturing operations, often supported by a relevant degree or certifications. Familiarity with MES platforms (like Wonderware or Siemens), SQL databases, and industrial automation systems is typically required. Strong analytical, problem-solving, and communication skills are crucial for troubleshooting issues and collaborating with cross-functional teams. These competencies are vital to ensure seamless integration, uptime, and optimization of manufacturing execution systems within production environments.

What are common challenges faced by MES System Administrators during system upgrades or integrations?

MES System Administrators often encounter challenges such as coordinating downtime with production teams, ensuring data integrity during migrations, and troubleshooting compatibility issues between legacy systems and new software versions. They must also manage user training for updated interfaces and workflows, and closely collaborate with IT, engineering, and production staff to minimize disruptions. Proactive planning, thorough testing, and clear communication are essential to successfully navigate these upgrade or integration projects.

What is the difference between Mes System Administrator vs Manufacturing Engineer?

AspectMes System AdministratorManufacturing Engineer
CredentialsIT certifications, knowledge of MES softwareEngineering degree, manufacturing process knowledge
Work EnvironmentIT departments, production floors with MES systemsDesign labs, production lines, plant floors
Industry UsageManufacturing, industrial automationManufacturing, process optimization
Primary FocusMaintaining and supporting MES systemsImproving manufacturing processes and efficiency

The Mes System Administrator primarily manages and supports Manufacturing Execution Systems (MES), ensuring smooth operation of manufacturing software. In contrast, a Manufacturing Engineer focuses on optimizing manufacturing processes and designing production workflows. While both roles work within manufacturing environments, the Mes System Administrator emphasizes IT and software support, whereas the Manufacturing Engineer concentrates on process improvement and engineering solutions.

What states have the most Mes System Administrator jobs?

States with the most job openings for Mes System Administrator jobs include:

What are popular job titles related to Mes System Administrator jobs?

For Mes System Administrator jobs, the most frequently searched job titles are:

Infographic showing various Mes System Administrator job openings in the United States as of September 2026, with employment types broken down into 1% As Needed, 85% Full Time, 12% Part Time, and 2% Contract. Highlights an 91% Physical, 2% Hybrid, and 7% Remote job distribution, with an average salary of $88,927 per year, or $42.8 per hour.

Manufacturing Systems and Master Data Administrator

Sacramento, CA • On-site

Orca Bio
Pharmaceutical and Medicine Manufacturing • 51 - 200 employees
Learn more about Orca Bioexternal

$90K - $120K/yr

Full-time

Medical, Dental, Vision, Life, Retirement, PTO

Posted 26 days ago

Job description

More than one million people in the United States today are fighting blood cancer. While a traditional allogeneic stem cell transplant has been the best hope for many, the transplant itself can prove fatal or lead to serious conditions, such as graft vs. host disease. Orca Bio is a commercial-stage biotechnology company redefining the transplant process by developing next-generation cell therapies with the goal of providing significantly better survival rates with dramatically fewer risks. With our purified, high-precision cell therapies we hope to not only replace patients' blood and immune systems with healthy ones, but also restore their lives.
 
We have built a state-of-the-art, 100,000-square-foot manufacturing facility in Sacramento, CA (7910 Metro Air Pkwy) to ensure the consistent and reliable delivery of our high-precision cell therapy products. This site is essential to advancing our clinical pipeline and supporting future commercial availability of our life-saving therapies.

Position Summary:

The Manufacturing Systems & Master Data Administrator serves as the business owner and super user for the company's Manufacturing Execution System (MES) and related manufacturing and supply chain applications. This role is responsible for governing manufacturing master data, driving system improvements, optimizing business processes, and ensuring system capabilities effectively support GMP manufacturing, inventory management, procurement, quality, planning, and commercial operations.

The Administrator owns the creation and maintenance of manufacturing and supply chain master data, including material masters, inventory masters, Bills of Materials (BOMs), product specifications, packaging configurations, vendor master records, release testing requirements, and manufacturing data.

In addition, this role leads continuous improvement initiatives for ERP/MES functionality, serves as the primary business liaison to Information Technology, Finance and Software vendors, and ensures business systems evolve to meet operational and regulatory needs. No direct reports.

Essential Duties and Responsibilities
  • Serve as the business owner / user for ERP, MES, and related manufacturing systems ensuring systems align with operational requirements and GMP compliance.
    • Develop and maintain manufacturing system standards, procedures, and work instructions.
    • Partner with IT and software vendors to resolve system issues and implement improvements.
    • Lead User Acceptance Testing (UAT), business validation activities, and deployment of system upgrades.
    • Develop business requirements and functional specifications for new capabilities and enhancements.
  • Own all material master records within Material Management (ERP/MES) systems.
    • Create and maintain raw materials, consumables, packaging, labels, and finished goods.
    • Create and maintain inventory attributes, storage conditions, shelf life, and lot control parameters.
    • Create and maintain Bills of Materials (BOMs).
    • Maintain manufacturing recipes and packaging configurations (where applicable).
    • Maintain material specifications and approved supplier information.
    • Link release testing requirements and quality specifications to materials.
    • Create and maintain vendor master records in partnership with Procurement.
    • Manage units of measure, conversion factors, and planning parameters.
  • Support engineering changes, change controls, and product introductions.
  • Ensure data integrity and GMP compliance.
  • Coordinate master data changes and system changes across Procurement, Manufacturing, Quality, MSAT, and Supply Chain.
Required Qualifications:
  • Bachelor's degree in Engineering, Supply Chain, Information Systems, Business, Life Sciences, Computer Science, or a related discipline.
  • 3+ years of experience in manufacturing systems, supply chain systems, ERP/MES administration, manufacturing operations, or master data management.
  • Experience in pharmaceutical, biotechnology, cell therapy, gene therapy, or other GMP-regulated manufacturing environments.
  • Experience serving as a business owner or super user for ERP and/or MES systems.
  • Experience implementing or enhancing ERP/MES solutions in a manufacturing environment
  • Excellent interpersonal, leadership, and communication skills.
  • Experience with autologous or allogeneic cell therapy supply chains, preferred.
  • Certification in Production and Inventory Management or Logistics, such as APICS are a plus 

     

$90,000 - $120,000 a year
The anticipated annual salary range for this job is based on prior experience in the role/industry, education, location, internal equity, and other job-related factors as permitted by law. For remote-based positions, this range may vary based on your local market. Full-time employment positions will also be eligible to receive pre-IPO equity and annual bonus, in addition to competitive medical, dental, and vision benefits, PTO, 401(k) plan, life and accidental death and disability coverage, and parental leave benefits. Other perks include subsidized daily lunches and snacks at our on-site locations.
 
Who we are
 
We are driven by a passion for science and compassion for patients. We act with urgency to ensure our treatments are one day accessible to all who need them.
 
We live by our core values of passion, courage, and integrity. Excellence in our work means the chance to unlock a better quality of life for our patients, and with that comes tremendous responsibility.
 
We innovate on a path that hasn't been paved. We embrace an entrepreneurial spirit and take calculated risks to achieve our mission. We aren't afraid to ask "why not" and challenge the status quo.
 
We maintain a start-up culture of camaraderie and leadership by example, regardless of title.
 
We're proud to be an equal opportunity employer, and recognize that celebrating our differences creates stronger, lasting solutions that better serve our team, our patients and their healthcare providers.
 
Notice to staffing firms
 
Orca Bio does not accept resumes from staffing agencies with which we do not have a written agreement and specific engagement for a particular opening. Our employment activities, inquiries and offers are managed through our HR/Talent team, and all candidates are presented through this channel only. We do not accept unsolicited resumes, and we rarely outsource recruitment.
We may use artificial intelligence (AI) tools to support parts of the hiring process, such as reviewing applications, analyzing resumes, or assessing responses and identifying potential inconsistencies or verification signals in application materials based on available information. These tools assist our recruitment team but do not replace human judgment. Final hiring decisions are ultimately made by humans. If you would like more information about how your data is processed, please contact us.
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