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Mes System Administrator Jobs in Indiana (NOW HIRING)

Howmet

Manufacturing Business Analyst

La Porte, IN · On-site

... Administrator and maintain lot integrity across production operations. * Support inventory ... Pull, clean, and consolidate production data from MES systems including OHCMS, establish and ...

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Mes System Administrator information

What is a MES System Administrator?

MES System Administrators are IT professionals responsible for managing, maintaining, and supporting Manufacturing Execution Systems (MES) within a production environment. They ensure the MES software is properly configured, updated, and integrated with other enterprise systems such as ERP and SCADA. Their role includes troubleshooting system issues, managing user access, maintaining data integrity, and ensuring system performance to support manufacturing operations. By overseeing the MES, they help ensure efficient production tracking, quality control, and real-time monitoring on the factory floor.

What skills and qualifications are needed to be a MES System Administrator?

To thrive as a MES System Administrator, you need a solid background in computer science, database management, and manufacturing operations, often supported by a relevant degree or certifications. Familiarity with MES platforms (like Wonderware or Siemens), SQL databases, and industrial automation systems is typically required. Strong analytical, problem-solving, and communication skills are crucial for troubleshooting issues and collaborating with cross-functional teams. These competencies are vital to ensure seamless integration, uptime, and optimization of manufacturing execution systems within production environments.

What are common challenges faced by MES System Administrators during system upgrades or integrations?

MES System Administrators often encounter challenges such as coordinating downtime with production teams, ensuring data integrity during migrations, and troubleshooting compatibility issues between legacy systems and new software versions. They must also manage user training for updated interfaces and workflows, and closely collaborate with IT, engineering, and production staff to minimize disruptions. Proactive planning, thorough testing, and clear communication are essential to successfully navigate these upgrade or integration projects.

What is the difference between Mes System Administrator vs Manufacturing Engineer?

AspectMes System AdministratorManufacturing Engineer
CredentialsIT certifications, knowledge of MES softwareEngineering degree, manufacturing process knowledge
Work EnvironmentIT departments, production floors with MES systemsDesign labs, production lines, plant floors
Industry UsageManufacturing, industrial automationManufacturing, process optimization
Primary FocusMaintaining and supporting MES systemsImproving manufacturing processes and efficiency

The Mes System Administrator primarily manages and supports Manufacturing Execution Systems (MES), ensuring smooth operation of manufacturing software. In contrast, a Manufacturing Engineer focuses on optimizing manufacturing processes and designing production workflows. While both roles work within manufacturing environments, the Mes System Administrator emphasizes IT and software support, whereas the Manufacturing Engineer concentrates on process improvement and engineering solutions.

Infographic showing various Mes System Administrator job openings in Indiana as of September 2026, with employment types broken down into 1% As Needed, 77% Full Time, 20% Part Time, and 2% Contract. Highlights an 91% Physical, 2% Hybrid, and 7% Remote job distribution.

Senior Principal Engineer - Automation Engineering - Process, Lab & Enterprise Systems Integration-L

Indianapolis, IN • On-site

Scorpion Therapeutics
51 - 200 employees
Learn more about Scorpion Therapeuticsexternal

Other

Posted 11 days ago

Job description

Responsibilities
  • Provide automation support for one or more operating areas across site and/or for capital projects; support right-first-time facility startup and ongoing manufacturing operations.
  • Ensure reliable and compliant control applications and systems are used in manufacturing; mentor employees and provide technical expertise across process control organization and functional disciplines.
  • During project delivery/startup (2025-2029), collaborate to build new organization systems and business processes supporting GMP operations and site culture.
  • Support Foundry DeltaV- and Rockwell-controlled process PLC equipment for Lab/Admin building and Laboratory analytical systems, including administration/configuration, analytical integration, and recipe setup/maintenance.
Key Objectives/Deliverables
  • Mentor process control team (design, controls philosophy, implementation, commissioning).
  • Implement/coordinate process control work.
  • Develop and implement the Automation Engineering Project Plan.
Operational Excellence
  • Lead/oversee Site Area leads and System Integrator (functional requirements, design specs, DCS application software, test specs); conduct design reviews and attend FATs.
  • Own lab/analytical equipment administration strategy (user access, data management/integration, backup/restore); supervise third-party execution and set configuration standards.
  • Partner on Empower, LIMS (LabVantage), MES, and ELN integration touchpoints.
  • Lead/mentor analytical systems support engineers; lead automation engineers supporting commissioning; provide project status updates.
  • Develop functional requirements/control strategies; perform DCS software design/coding/config/testing; design/tune/troubleshoot control loops; implement/support plant historians.
  • Maintain validated state of control systems via validation strategies/documentation; provide automation support for capital projects (new product introductions); promote automation for productivity/efficiency/compliance.
Organizational Capability
  • Set standards/rigor for automation work products; plan/prioritize; continuous improvement; influence peers/partners; strong communication.
  • Knowledge of GMP, regulatory requirements, and computer system validation.
Basic Requirements
  • B.S. in Engineering or Science; 8+ years automation engineering/biopharma engineering/operations/manufacturing; experience with laboratory/analytical systems and system integration.
  • Experience commissioning/qualifying/supporting analytical and automation-controlled lab equipment (e.g., UHPLC/chromatography, mass spectrometers, single-use bioreactors, RX-10 controls, Rockwell PLC autoclaves/parts washers).
  • Authorized to work in the United States full-time; company does not sponsor visas.
Additional Preferences
  • Greenfield automated manufacturing site experience using SCADA/DCS/MES/LIMS/site historian (DeltaV, Rockwell, Syncade, LabVantage, OSI PI).
  • Experience facilitating and driving organizational-level decisions.
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