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Mes Manufacturing Execution System Jobs in Raleigh, NC

Vulcan Elements

Process Engineer

Benson, NC

Familiarity with MES (Manufacturing Execution Systems) implementation and automated transaction mapping. * Experience in highly regulated industries such as Defense (DoD), Aerospace (AS9100), or ...

Amgen, Inc.

Mfg Tecnologies Sr Mgr

Holly Springs, NC · On-site

$78K - $107K/yr

In this vital role, you will manage a defined set of Manufacturing Execution Systems (MES) objects, such as GMBRs (electronic batch records) and equipment management objects (ESPs, state diagrams ...

Amgen

Mfg Tecnologies Sr Mgr

Holly Springs, NC · On-site +1

In this vital role, you will manage a defined set of Manufacturing Execution Systems (MES) objects, such as GMBRs (electronic batch records) and equipment management objects (ESPs, state diagrams ...

Accenture

Industry X- MES PAS-X Consultant

Raleigh, NC · On-site

$30.67 - $98.94/hr

Lead in the design, development, documentation, and implementation of Korber PAS-X Manufacturing Execution Systems (MES) * Design/Author/Develop/Configure Electronic Batch Records (EBR) * Implement ...

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Mes Manufacturing Execution System information

See Raleigh, NC salary details

$39.4K

$107.1K

$154.1K

How much do mes manufacturing execution system jobs pay per year?

As of Aug 10, 2026, the average yearly pay for mes manufacturing execution system in Raleigh, NC is $107,139.00, according to ZipRecruiter salary data. Most workers in this role earn between $82,600.00 and $138,500.00 per year, depending on experience, location, and employer.

What does a MES Manufacturing Execution System do?

In a MES Manufacturing Execution System position, your day-to-day tasks will typically involve configuring, monitoring, and maintaining MES software to ensure smooth manufacturing operations. You will collaborate closely with production, quality, and IT teams to troubleshoot system issues, optimize workflows, and implement process improvements. Regular responsibilities include data analysis, user support, system upgrades, and interfacing MES with other enterprise systems like ERP or SCADA. This role offers a dynamic mix of hands-on technical work and cross-departmental coordination, ideal for those who enjoy problem-solving and driving efficiency.

What is a MES Manufacturing Execution System?

A MES Manufacturing Execution System job involves managing and optimizing manufacturing operations through software solutions that track production data, improve workflow efficiency, and ensure quality control. Professionals in this role work closely with production teams, IT departments, and engineers to implement and maintain MES applications. Responsibilities may include configuring MES software, troubleshooting system issues, integrating with enterprise systems like ERP, and analyzing manufacturing performance. This role is critical for ensuring real-time visibility into production processes, enhancing automation, and driving continuous improvement in manufacturing environments.

What are the key skills and qualifications needed to thrive in the MES Manufacturing Execution System position?

To excel in a MES (Manufacturing Execution System) role, a solid background in manufacturing processes, process automation, and IT systems is essential, often supported by a degree in engineering, computer science, or a related field. Familiarity with MES software such as Siemens Opcenter, Rockwell FactoryTalk, or Wonderware, as well as certifications in relevant platforms, is highly valued. Strong analytical, problem-solving, and communication skills help you effectively collaborate with cross-functional teams and respond to production challenges. These competencies are crucial for ensuring seamless system integration, efficient production workflows, and continuous process improvement within manufacturing operations.

What are popular job titles related to Mes Manufacturing Execution System jobs in Raleigh, NC? For Mes Manufacturing Execution System jobs in Raleigh, NC, the most frequently searched job titles are:
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Mes Manufacturing Execution System jobs near you
Infographic showing various Mes Manufacturing Execution System job openings in Raleigh, NC as of August 2026, with employment types broken down into 1% As Needed, 81% Full Time, 13% Part Time, and 5% Contract. Highlights an 92% Physical, 2% Hybrid, and 6% Remote job distribution, with an average salary of $107,139 per year, or $51.5 per hour.

Senior Pharmaceutical Automation Engineer

Visium Resources, Inc.

Clayton, NC • On-site

$58 - $78/hr

Contractor

Medical

Posted 20 days ago

Job description

Introduction
Visium Resources has been asked to identify qualified candidates for this Senior Pharmaceutical Automation Engineer position. This position is a 12 month contract with anticipated renewals at a large Pharmaceutical company in Clayton, NC. This position is 5 days per week onsite.


Summary

We are seeking an experienced Senior Pharmaceutical Automation Engineer to support the implementation, commissioning, qualification, startup, and operational readiness of automated manufacturing systems for a major Fill Finish Expansion (FFEx) project within a state-of-the-art pharmaceutical manufacturing facility.


This role will provide technical automation support across multiple production and packaging systems, ensuring automation platforms are installed, tested, validated, and transitioned into reliable manufacturing operations while meeting FDA, cGMP, GAMP 5, and corporate quality standards. The ideal candidate possesses strong PLC, SCADA, MES, and pharmaceutical manufacturing automation experience with demonstrated success supporting highly automated production environments.


Primary Responsibilities

  • Provide automation engineering support for pharmaceutical manufacturing and packaging equipment throughout installation, commissioning, qualification, startup, and production support.
  • Troubleshoot and resolve automation-related issues impacting manufacturing operations.
  • Support Factory Acceptance Testing (FAT), Site Acceptance Testing (SAT), Commissioning, Installation Qualification (IQ), Operational Qualification (OQ), and Performance Qualification (PQ) activities.
  • Review, troubleshoot, and modify PLC, HMI, SCADA, MES, and industrial network configurations as required.
  • Coordinate automation activities with engineering, validation, manufacturing, quality assurance, vendors, and system integrators.
  • Support change controls, deviations, CAPAs, and root cause investigations related to automation systems.
  • Participate in startup planning and execution while minimizing production downtime.
  • Develop and maintain automation documentation including:
    • Functional Specifications
    • Design Specifications
    • Software Change Documentation
    • Test Protocols
    • SOPs
    • System Configuration Documentation
  • Assist in cybersecurity, backup, disaster recovery, and system lifecycle management.
  • Ensure automation systems comply with FDA 21 CFR Part 11, cGMP, GAMP 5, and data integrity requirements.
  • Support long-term reliability improvements and continuous process optimization.

Manufacturing Equipment Supported

The Automation Engineer will support automation systems associated with highly automated pharmaceutical manufacturing and packaging equipment including:


Assembly Operations

FlexTouch (FxT) Assembly Lines

  • Mikron Assembly FlexCells
  • Mikron Handling Units
    • HUGP - Good Pen
    • HUMM - Motor Module
    • HUSA - Sub Assembly
  • Automated Palletizer


SDD Assembly Line

  • Cell 10 & 20 - Load SU/FA & Laser Mark
  • Cell 30 & 35 - Load Syringe
  • Cell 38 & 40 - Device Assembly
  • Cell 50


Packaging Operations

Support multi-vendor automated packaging equipment including:

  • Pester Depalletizer
  • Bausch + Stroebel Labeler
  • Fargo (Koerber) Transfer Unit
  • Dividella Cartoner
  • Robomat NeedlePak
  • Uhlmann Unit Serialization Platform (USP)
  • Uhlmann Track & Trace
  • Pester End-of-Line Palletizer
  • Automation Systems


Candidates should have experience with several of the following technologies:


PLC Platforms

  • Schneider Electric
  • B&R Automation
  • Allen-Bradley ControlLogix
  • Siemens PLCs


SCADA & HMI

  • FactoryTalk View
  • FactoryTalk Services
  • SCADA troubleshooting
  • Industrial HMI development


Manufacturing Systems

  • PAS-X Manufacturing Execution System (MES)
  • Historian systems
  • SQL Server
  • AVEVA PI System


Vision Systems

  • Cognex
  • Keyence
  • Vision Automation


Serialization

  • Uhlmann Track & Trace
  • Pharmaceutical serialization systems


Infrastructure

  • ThinManager
  • Octoplant
  • Industrial Ethernet networks
  • Virtualized automation environments
  • Windows Server administration (automation-related)


Required Qualifications

  • Bachelor's degree in Engineering, Automation Engineering, Electrical Engineering, Computer Engineering, or related technical discipline.
  • 5+ years of pharmaceutical or biotechnology automation engineering experience.
  • Experience supporting FDA-regulated manufacturing facilities.
  • Strong PLC troubleshooting experience with one or more major PLC platforms.
  • Experience supporting SCADA systems in pharmaceutical manufacturing.
  • Working knowledge of MES integration.
  • Experience supporting commissioning and qualification activities.
  • Understanding of ISA-88 and ISA-95 principles.
  • Familiarity with 21 CFR Part 11 and electronic records compliance.
  • Excellent troubleshooting and root cause analysis skills.
  • Strong communication and cross-functional collaboration abilities.


Preferred Qualifications

  • 8+ years of pharmaceutical automation engineering experience.
  • Experience supporting Fill Finish manufacturing facilities.
  • Experience with device assembly or high-speed packaging equipment.
  • Previous Novo Nordisk project experience.
  • Experience with PAS-X MES.
  • Experience with FactoryTalk SCADA architecture.
  • Knowledge of serialization systems.
  • Experience with AVEVA PI Historian.
  • Familiarity with ThinManager and Octoplant.
  • Experience supporting validated manufacturing environments.

Knowledge & Skills

  • PLC programming and troubleshooting
  • Industrial automation architecture
  • SCADA systems
  • MES integration
  • Industrial networking
  • Validation support
  • Commissioning and startup
  • Equipment integration
  • Root cause analysis
  • Change management
  • Vendor coordination
  • Continuous improvement
  • Pharmaceutical manufacturing operations
  • Data integrity and compliance
  • Technical documentation


Work Environment

  • On-site support within an active pharmaceutical manufacturing facility.
  • Frequent interaction with manufacturing, engineering, validation, quality, and equipment vendors.
  • Ability to support commissioning, startup, off-shift troubleshooting, and occasional weekend activities during project milestones.
  • May require gowning and work within classified manufacturing areas.

Company Description

Visium Resources is an award-winning employment firm with a mission to match talented individuals with highly successful organizations. At Visium, our company’s success is based on your success. When you work with us, you are never “just a number”. You are our most important asset. Here, you will know us by name through our regular visits to client sites and even occasional luncheons. We will always be there when you need assistance and will always go the extra mile to ensure that you are as successful as possible. Whether you're looking for contract, contract-to-hire or permanent opportunities, we firmly believe there is no employment agency that will work harder for you than Visium. Visium Resources is an equal opportunity employer and values diversity. All employment is decided based on qualifications, merit and business need.