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Mes Engineer Jobs in Massachusetts (NOW HIRING)

MES Engineer Location : Boston Area (On site in Norwood, MA) Department: Internal DP Operations Systems Regulatory Relevance: GxP Primary System : Apprentice Tempo MES Role Overview: The MES Engineer ...

MES Engineer

Devens, MA

$89K - $108K/yr

The MES Engineer is a technical contributor responsible for the configuration, implementation, and support of Manufacturing Execution System (MES) solutions within the Devens Cell Therapy Facility.

MES Engineer

Devens, MA · On-site

$89K - $108K/yr

The MES Engineer is a technical contributor responsible for the configuration, implementation, and support of Manufacturing Execution System (MES) solutions within the Devens Cell Therapy Facility.

MES Engineer

Devens, MA · On-site

$89K - $108K/yr

The MES Engineer is a technical contributor responsible for the configuration, implementation, and support of Manufacturing Execution System (MES) solutions within the Devens Cell Therapy Facility.

MES Engineer

Devens, MA

$89K - $108K/yr

The MES Engineer is a technical contributor responsible for the configuration, implementation, and support of Manufacturing Execution System (MES) solutions within the Devens Cell Therapy Facility.

MES Engineer

Foxboro, MA · On-site

$110K - $151K/yr

They are seeking a Senior MES Engineer to support Manufacturing Execution Systems (MES) and related interfaces, focusing on improving MES functionality to meet customer requirements while ...

MES Engineer

Foxboro, MA · On-site

$110K - $151K/yr

They are seeking a Senior Engineer to support Manufacturing Execution Systems (MES) and enhance their functionality to meet customer requirements while collaborating with experienced engineers.

A SENIOR MES ENGINEER

Devens, MA

$116K - $159K/yr

Minimum four (4) years of design/development/deployment experience in Emerson Syncade MES. DeltaV Batch programming or Syncade Recipe development experience. Work experience in a Pharmaceutical ...

MES Automation Engineer. We are looking for MES Automation Engineer, to provide engineering and technical support for manufacturing execution systems and digital systems in the Bio-pharmaceutical ...

Job title - GxP MES System engineer. Work location - USA - Norwood (MA) Is it Hybrid, onsite or remote position - Onsite - Client office Tentative Start date - 1st Sep 2026 Contract duration - 6 ...

MES Analyst

Marlborough, MA · On-site

$110K - $135K/yr

The MES Analyst will be responsible for overseeing the adoption/development/and support of Ken ... Partner with operations, QA, maintenance, engineering, and IT teams to improve manufacturing ...

MES Analyst

Marlborough, MA · On-site

$110K - $135K/yr

The MES Analyst will be responsible for overseeing the adoption/development/and support of Ken ... Manufacturing & Operations Support Partner with operations, QA, maintenance, engineering, and IT ...

MES Analyst

Marlborough, MA · On-site

$110 - $135/hr

Partner with operations, QA, maintenance, engineering, and IT teams to improve manufacturing ... Ensure MES functionality aligns with food safety, traceability, and regulatory compliance ...

MES Analyst

Marlborough, MA · On-site

$110K - $135K/yr

The MES Analyst will be responsible for overseeing the adoption/development/and support of Ken ... Partner with operations, QA, maintenance, engineering, and IT teams to improve manufacturing ...

Senior Engineer, MES Development Location: 38 Jackson Road, Devens, MA 01434 Wage Range: $149,288.00 - $162,170.00 Bristol-Myers Squibb Company is hiring a(n) Senior Engineer, MES Development (in ...

New

Bachelor's degree in Engineering-related discipline * 3+ years of experience in core manufacturing ... Experience with Manufacturing Executing System (MES) configuration and implementation The wage ...

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Showing results 1-20

Mes Engineer information

See Massachusetts salary details

$48.1K

$116.2K

$189.5K

How much do mes engineer jobs pay per year?

As of Aug 23, 2026, the average yearly pay for mes engineer in Massachusetts is $116,187.00, according to ZipRecruiter salary data. Most workers in this role earn between $83,000.00 and $144,700.00 per year, depending on experience, location, and employer.

What does a MES engineer do?

A MES (Manufacturing Execution Systems) Engineer is responsible for designing, implementing, and maintaining MES solutions that optimize manufacturing operations. They bridge the gap between enterprise systems (such as ERP) and shop floor equipment to improve production efficiency, data collection, and process automation. MES Engineers work with various stakeholders to integrate software, troubleshoot issues, and ensure seamless data flow across manufacturing processes. Their role is critical in enhancing productivity, reducing downtime, and ensuring compliance with industry standards.

What are the key skills and qualifications needed to thrive as a MES engineer?

To thrive as a MES Engineer, you need a solid background in manufacturing processes, information systems, and a relevant degree in engineering or computer science. Familiarity with MES platforms like Siemens SIMATIC IT, Rockwell FactoryTalk, or Wonderware, as well as knowledge of automation, PLCs, and database management, is essential. Strong problem-solving skills, attention to detail, and effective communication are key soft skills for collaborating with cross-functional teams and troubleshooting system issues. These competencies ensure MES Engineers can effectively bridge the gap between IT and manufacturing, optimize production workflows, and maintain compliant operations.

What are the common responsibilities of a MES engineer on a typical workday?

MES Engineers are usually responsible for configuring, deploying, and maintaining Manufacturing Execution Systems, as well as troubleshooting issues that arise on the shop floor. A typical day may involve gathering user requirements, integrating MES solutions with ERP or automation systems, performing software updates, and supporting production teams with system-related concerns. Collaboration with quality assurance, IT, and manufacturing staff is frequent to ensure seamless operations and compliance with industry standards. This role demands both hands-on technical tasks and ongoing communication with multiple stakeholders to achieve optimal production efficiency.

How to become a MES engineer?

To become a Manufacturing Execution System (MES) engineer, you typically need a bachelor's degree in engineering, computer science, or a related field. Gaining experience with industrial automation, manufacturing processes, and MES software such as Siemens, Rockwell, or Wonderware is essential, along with developing skills in programming, systems integration, and data analysis. Certifications in industrial automation or specific MES platforms can enhance job prospects.

What are the most commonly searched types of Mes Engineer jobs in Massachusetts?

The most popular types of Mes Engineer jobs in Massachusetts are:

What are popular job titles related to Mes Engineer jobs in Massachusetts?

For Mes Engineer jobs in Massachusetts, the most frequently searched job titles are:

What cities in Massachusetts are hiring for Mes Engineer jobs?

Cities in Massachusetts with the most Mes Engineer job openings:

Infographic showing various Mes Engineer job openings in Massachusetts as of August 2026, with employment types broken down into 95% Full Time, 2% Part Time, and 3% Contract. Highlights an 85% Physical, 6% Hybrid, and 9% Remote job distribution, with an average salary of $116,187 per year, or $55.9 per hour.

Other

Posted 19 days ago


Job description

Position Title: MES Engineer
Location: Boston Area (On site in Norwood, MA)

Department: Internal DP Operations Systems Regulatory Relevance: GxP

Primary System: Apprentice Tempo MES


Role Overview:

The MES Engineer will play a critical role in supporting the design, development, implementation and management of the Manufacturing Execution Solutions (MES) within the organization''s Drug Product manufacturing area. This role involves translating manufacturing processes into robust MES solutions, ensuring compliance with GxP standards, and integrating MES with other enterprise systems and automation platforms to streamline operations.


Key Responsibilities:

·       MES Support and Development:

o   Assist in the design and configuration of Tempo MES solutions, including electronic batch records (eBRs), under the guidance of senior engineers.

o   Contribute to the development of modular, scalable, and reusable MES recipe templates based on ISA 88/95 standards.

o   Perform impact assessments for recipe modifications and system updates, ensuring adherence to GxP requirements.

o   Collaborate with cross-functional teams to gather user requirements and define functional specifications for MES functionalities.

o   Assist in recipe design and authoring electronic batch records (eBR) to develop modular, scalable and reusable MES recipe and equipment workflow templates following ISA 88/95 standards.

o   Perform root cause analysis and resolve MES issues related to system configuration, recipe design, or integration failures.

·       System Integration and Analytics:

o   Support efforts to integrate MES with other enterprise systems, such as ERP, LIMS, and automation platforms, using industry-standard protocols like OPC or RESTful APIs.

o   Assist in the development of data visualization tools and reporting dashboards to support operational decision-making.

o   Possess technical knowledge in DCS, automation, and systems integration, including the design and management of data dashboards, label management systems, and reporting tools.

·       Operational Support:

o   Provide day-to-day technical support for MES system users, assisting in troubleshooting and resolving recipe or system-related issues.

o   Participate in technical transfer activities to ensure smooth onboarding of new products and processes into manufacturing.

o   Support off-hours manufacturing operations as needed to address critical MES-related issues.

·       Compliance and Documentation:

o   Ensure compliance with Good Documentation Practices (GDP), GxP regulations, Data Integrity guidelines and company policies during all MES-related activities.

o   Participate in validation activities to support the implementation and ongoing maintenance of MES systems.


Required Qualifications:

·       Education:

o   Bachelor’s degree in Engineering, Computer Science, or a related technical field.

·       Experience:

o   2-4 years of experience with MES systems, preferably some in Drug Product manufacturing in pharmaceutical or biotechnology environments.

o   Basic understanding of GxP regulations, GAMP guidelines, and Computer System Validation (CSV).

·       Technical Skills:

o   Exposure to MES platforms such as Tempo, Syncade, or equivalent systems is preferred.

o   Familiarity with basic programming concepts or languages like SQL, Python, or C#.

o   General knowledge of manufacturing processes, automation systems, and systems integration principles.


Additional Competencies:

  • Strong problem-solving and analytical skills with a willingness to learn and adapt quickly.
  • Effective communication and collaboration abilities to work in cross-functional teams.
  • Commitment to maintaining compliance with regulatory and internal standards.