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Manufacturing Assistant Jobs in California (NOW HIRING)

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Manufacturing Assistant information

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How much do manufacturing assistant jobs pay per hour?

As of Aug 10, 2026, the average hourly pay for manufacturing assistant in California is $20.27, according to ZipRecruiter salary data. Most workers in this role earn between $16.15 and $20.87 per hour, depending on experience, location, and employer.

What does a manufacturing assistant do?

A Manufacturing Assistant supports the production process in a manufacturing facility by performing a variety of tasks, such as assembling products, operating machinery, and ensuring quality standards are met. They may also be responsible for maintaining equipment, managing inventory, and keeping the workspace organized. Manufacturing Assistants work closely with other team members and follow safety protocols to ensure efficient and safe operations. Their role is essential in keeping the production line running smoothly and efficiently.

What is the difference between Manufacturing Assistant vs Production Worker?

AspectManufacturing AssistantProduction Worker
CredentialsHigh school diploma or equivalent; some roles may require basic technical skillsHigh school diploma or equivalent; on-the-job training often provided
Work EnvironmentFactories, assembly lines, manufacturing plantsFactories, assembly lines, manufacturing plants
Job ResponsibilitiesSupporting manufacturing processes, preparing materials, assisting techniciansOperating machinery, assembling products, performing manual tasks
Industry UsageCommonly used in manufacturing settings for support rolesPrimarily involved in direct production activities

Manufacturing Assistants typically support production teams by preparing materials and assisting technicians, while Production Workers focus on operating machinery and assembling products. Both roles are essential in manufacturing environments and often require similar credentials and work settings.

What are the key skills and qualifications needed to thrive as a manufacturing assistant?

To thrive as a Manufacturing Assistant, you need a solid understanding of production processes, attention to detail, and a high school diploma or equivalent. Familiarity with manufacturing equipment, safety protocols, and inventory management systems is often required. Strong teamwork, communication, and problem-solving skills help you adapt quickly and support efficient operations. These skills and qualities are essential for maintaining productivity, ensuring safety, and contributing to seamless manufacturing workflows.
What are the most commonly searched types of Manufacturing jobs in California? The most popular types of Manufacturing jobs in California are:
What cities in California are hiring for Manufacturing Assistant jobs? Cities in California with the most Manufacturing Assistant job openings:
Manufacturing Assistant jobs near you
Infographic showing various Manufacturing Assistant job openings in California as of August 2026, with employment types broken down into 1% As Needed, 76% Full Time, 19% Part Time, 2% Temporary, and 2% Contract. Highlights an 98% Physical, 1% Hybrid, and 1% Remote job distribution, with an average salary of $42,158 per year, or $20.3 per hour.

Manufacturing Supervisor I - Shift B

Abzena Inc.

San Diego, CA • On-site

Full-time

Re-posted 9 days ago

Job description

With extensive experience in developing biologics and bioconjugates, we offer a seamless service delivered by fully integrated teams, from early discovery to commercial manufacturing.
Forward-thinking and committed, we find the best solution and use the right technologies to design, develop and manufacture your products to ensure we get vital medicines to patients quickly and safely.
We are dedicated to quality excellence. We are driven to get better treatments to market, efficiently and responsibly by reducing timelines and delivering the highest quality products and services.
We are Abzena. More than a CDMO, we are a responsible and dedicated partner that takes care of your products from concept to patient.
The Manufacturing Supervisor is responsible for leading GMP manufacturing operations supporting biologics production, including cell culture, fermentation, harvest, purification, and bulk drug substance manufacturing activities. This role provides direct supervision of manufacturing personnel, ensures compliance with current Good Manufacturing Practices (cGMP), and drives safe, efficient, and high-quality execution of manufacturing campaigns.
The supervisor serves as a key operational leader, coordinating production activities, managing shift resources, supporting technology transfer and process validation activities, and partnering with Quality, Process Sciences, Supply Chain, Facilities, and MSAT teams to achieve production objectives. This role will be dedicated to the manufacturing operations of Train 2. Train 2 is a production line going from vial thaw in initial thaw and expansion to a 500L production reactor, followed by harvest, to finishing operations in downstream.
Example Plan Shifts/Training Schedule:
- First 2 weeks: 8 hour shifts, M-F
- Next 1-2 months: 10 hour shifts, Mon-Thurs
- After 90 days: 12 hour shifts, Thurs-Sat & Alternating Wednesdays
Schedule is subject to change based on needs.
Responsibilities
Manufacturing Operations Leadership
  • Supervise day-to-day upstream and downstream GMP manufacturing operations.
  • Lead production activities including media and buffer preparation, cell culture expansion, bioreactor operations, harvest, chromatography, ultrafiltration/diafiltration (UF/DF), and bulk filling activities.
  • Ensure manufacturing campaigns are executed according to approved batch records, SOPs, and manufacturing schedules.
  • Coordinate shift activities and allocate resources to meet production requirements.
  • Monitor manufacturing performance and address operational challenges in real time.
  • Drive adherence to production schedules while maintaining quality and compliance standards.

Team Leadership & Development
  • Supervise, coach, mentor, and develop Manufacturing Associates and Senior Manufacturing Associates.
  • Conduct performance evaluations and establish development plans for team members.
  • Facilitate onboarding and qualification of new employees.
  • Promote a culture of safety, teamwork, accountability, and continuous improvement.
  • Lead daily shift meetings, production reviews, and operational communications.

GMP Compliance & Quality
  • Ensure strict compliance with cGMP regulations, company procedures, and regulatory requirements.
  • Review and verify batch documentation for accuracy and completeness.
  • Support investigations, deviations, CAPAs, change controls, and quality events.
  • Participate in internal audits, client audits, and regulatory inspections.
  • Ensure proper documentation practices and data integrity standards are maintained.

Process Execution & Technical Support
  • Provide technical oversight for upstream and downstream operations.
  • Support process transfers from development to GMP manufacturing.
  • Assist in process validation, engineering runs, and GMP campaign readiness activities.
  • Collaborate with MSAT, Process Development, and Engineering teams to improve process robustness and efficiency.
  • Troubleshoot manufacturing and equipment-related issues.

Safety & Operational Excellence
  • Champion Environmental Health and Safety (EHS) compliance.
  • Ensure safe handling of biological materials, chemicals, and manufacturing equipment.
  • Lead risk assessments and support implementation of corrective actions.
  • Drive Lean Manufacturing and continuous improvement initiatives.
  • Monitor and improve key performance indicators (KPIs) including safety, right-first-time execution, batch success rate, and schedule adherence.

Cross-Functional Collaboration
  • Partner with Quality Assurance, Quality Control, Validation, Facilities, Engineering, Supply Chain, and Program Management teams.
  • Support customer visits and client-facing manufacturing discussions as required.
  • Ensure manufacturing readiness through effective planning and material coordination.

Qualifications
  • Bachelor's degree in Biotechnology, Biochemistry, Biology, Chemical Engineering, Bioprocess Engineering, or related scientific discipline. (Master's degree preferred)
  • 5-8 years of experience in biopharmaceutical manufacturing within a GMP-regulated environment.
  • Minimum 2 years of leadership or supervisory experience.
  • Hands-on experience with both upstream and downstream biologics manufacturing operations.
  • Experience supporting commercial, late-stage clinical, or process validation manufacturing campaigns.
  • Mammalian cell culture and/or microbial fermentation operations.
  • Single-use bioreactor systems.
  • Chromatography systems (ÄKTA or equivalent).
  • Tangential Flow Filtration (TFF), UF/DF operations.
  • Media and buffer preparation.
  • GMP documentation practices.
  • Electronic systems such as MES, Veeva, TrackWise, DeltaV, SAP, or equivalent platforms.
  • Familiarity with FDA, EMA, MHRA, and ICH GMP requirements.

Travel between Abzena sites (local San Diego CA facilities ) as needed.
Preferred Qualifications
  • Experience in CDMO manufacturing environments.
  • Prior involvement with technology transfer and scale-up activities.
  • Lean Six Sigma certification or continuous improvement experience.
  • Experience managing multiple manufacturing campaigns simultaneously.
  • Knowledge of monoclonal antibody and recombinant protein manufacturing processes.

Physical Requirements
  • Ability to sit or stand for extended periods of time.
  • Frequently lift and or move objects at least 50 pounds in weight.
  • Stand/walk during the entire length of shift.
  • Use arms, hands and fingers to handle, feel or reach.
  • Ability to climb, balance, stoop, kneel, crouch, or crawl.
  • Visual abilities include near and far sight, color, peripheral vision, depth and ability to focus.

$100,000 - $120,000 a year
FLSA: Exempt
Abzena is an equal opportunity employer that is committed to diversity and inclusion in the workplace. We prohibit discrimination and harassment of any kind based on race, color, sex, religion, sexual orientation, national origin, disability, genetic information, pregnancy, or any other protected characteristic as outlined by federal, state, or local laws.
This policy applies to all employment practices within our organization, including hiring, recruiting, promotion, termination, layoff, recall, leave of absence, compensation, benefits, and training.

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