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$140.5K

$211.9K

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How much do lcms jobs pay per year?

As of Jun 25, 2026, the average yearly pay for lcms in the United States is $211,935.00, according to ZipRecruiter salary data. Most workers in this role earn between $205,000.00 and $220,000.00 per year, depending on experience, location, and employer.

What are the key skills and qualifications needed to thrive as an LCMS (Liquid Chromatography-Mass Spectrometry) Specialist, and why are they important?

To thrive as an LCMS Specialist, you need a solid background in analytical chemistry, laboratory techniques, and a relevant scientific degree such as chemistry, biochemistry, or a related field. Expertise in operating and troubleshooting LCMS instruments, data analysis software (like MassLynx or Xcalibur), and understanding of regulatory standards is typically required. Attention to detail, problem-solving abilities, and strong communication skills are crucial soft skills in this role. These competencies are essential for ensuring accurate data generation, maintaining instrument performance, and supporting research or quality control objectives.

What are LCMS jobs?

LCMS jobs refer to positions that involve working with Liquid Chromatography-Mass Spectrometry (LC-MS) technology, which is commonly used in analytical chemistry for identifying and quantifying compounds in complex mixtures. Professionals in these roles may operate LC-MS instruments, develop analytical methods, analyze data, and support research or quality control in fields such as pharmaceuticals, environmental science, and food testing. Typical job titles include LCMS Analyst, Scientist, or Technician, and they often require a background in chemistry, biochemistry, or a related field.

What Are LC-MS Jobs?

Liquid chromatography–mass spectrometry (LC-MS or LCMS) is the term for an analytical chemistry technique. Scientists use LC-MS to separate, isolate, and evaluate components of a compound. The duties of people in LC-MS jobs involve using instruments to perform analysis in a laboratory setting. Researchers, R&D scientists, and laboratory technicians use LC-MS techniques to test products in the food, cosmetic, and pharmaceutical industries. Scientists with chemical, agricultural, and biomedical qualifications also use this technique. After collecting data from the LC-MS equipment, your responsibilities include using your scientific skills to interpret your findings and, in some cases, apply the results to product development.

What are some common challenges faced by LCMS analysts and how can they be addressed?

LCMS analysts often encounter challenges such as troubleshooting instrument malfunctions, managing complex sample matrices, and ensuring accurate calibration and maintenance of equipment. Staying current with evolving analytical methods and software updates is essential. Proactively documenting procedures, participating in regular training, and collaborating closely with colleagues in quality control or research teams can help address these challenges and maintain high-quality analytical results.

What is the difference between Lcms vs Laboratory Technician?

AspectLcmsLaboratory Technician
Required CredentialsDegree in Chemistry, Biochemistry, or related field; certification often preferredHigh school diploma or associate degree; technical training
Work EnvironmentAnalytical labs, research facilities, pharmaceutical or environmental labsClinical, industrial, or research laboratories
Job FocusOperating and maintaining liquid chromatography-mass spectrometry equipment, data analysisSample preparation, testing, data recording, basic instrument operation

LCMS specialists focus on operating advanced analytical instruments like liquid chromatography-mass spectrometry, requiring specialized training and certifications. Laboratory Technicians perform broader testing tasks, often with less specialized equipment. While both roles work in laboratory settings, LCMS roles demand more technical expertise in analytical instrumentation, making them more specialized within the lab environment.

More about Lcms jobs
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Lcms jobs near you
Infographic showing various Lcms job openings in the United States as of June 2026, with employment types broken down into 86% Full Time, 7% Part Time, and 7% Contract. Highlights an 100% In-person job distribution, with an average salary of $211,935 per year, or $101.9 per hour.

Manager II Labs, Analytical - LCMS Lab

NSF

Ann Arbor, MI • On-site

Other

Posted 20 days ago

Job description

This job involves the management and coordination of people and instrumentation to keep preparation and analytical work smoothly flowing through one of two LCMS groups while meeting all quality and safety requirements.

With a legacy spanning more than 80 years, NSF leverages science and innovation to improve human and planet health. We provide science-driven, independent testing, inspection, certification, and advisory services and develop the very standards that drive the food, water, and life sciences industries worldwide. We empower our clients to navigate shifting regulations to improve consumer health, safety, and quality of life.

One of our core values is We Are One NSF. This means that while we're one team, we embrace the cultural, ethnic, language, and demographic diversity that reflects the societies in which we live and work.

Come join a team that makes a difference in the world. More information about NSF can be found at nsf.org.

NSF is an equal opportunity employer. All qualified applicants will receive consideration for employment without regard to, among other things, race, color, religion, sex, sexual orientation, gender identity, national origin, age, status as a protected veteran, or disability.

Notice to Agency and Search Firm Representatives: Please note that NSF is not accepting unsolicited resumes from agencies/search firms for this role. Resumes submitted to an NSF employee by a third-party agency without a valid written & signed search agreement between NSF and said third-party agency will become the sole property of NSF. No fee will be paid if a candidate is hired as a result of an unsolicited agency or search firm referral. Thank you.

NSF's global network of state-of-the-art laboratories is the "backbone" of NSF's comprehensive testing and certification services. Staffed by engineers, chemists, microbiologists and toxicologists, we offer world-class technical expertise across the food, water and life sciences industries.

REQUIRED QUALIFICATIONS: 

  • BS/BA in a directly related science field or an equivalent combination of experience and coursework.
  • 5 years plus of laboratory experience plus a minimum of 1-2 years of supervisory or management experience
  • Demonstrated management or supervisory skills in a laboratory environment. 
  • Knowledge of standard lab procedures and instrumentation. 
  • Able to work well in a production team environment with strong organizational skills.
  • Consistent attention to detail and verbal/written communication skills.
  • Computer skills with laboratory LIMS and instrumentation software. 

 

PREFERRED QUALIFICATIONS:

  • Demonstrated method development and/or troubleshooting skills with LCMS instrumentation.
  • Detailed instrumentation knowledge for work in area, including knowledge of instrument software.
  • Background/Knowledge in dietary supplement testing.
  • Knowledge of NSF/ANSI standards. 
  • Ability to work Saturday shift. 

PHYSICAL DEMANDS:

  • Ability to handle both desk and laboratory work environments. 
  • Train, develop, motivate, and evaluate a competent workforce in cooperation with the management team.
  • Overall responsibility to ensure that production targets and turnaround time goals are met.
  • Ensure that the team meets safety, quality, and cost control objectives, proactively identifying risks and driving corrective actions.
  • Coordinate resources between groups, particularly between the two LCMS teams. 
  • Provide technical oversight and help with troubleshooting/problem resolution as appropriate for testing in the LCMS group.
  • Ensure that equipment and instruments are appropriately maintained, and that lab documentation is well organized and up to date. 
  •  Ensure clear, effective communication across shifts and act as an escalation point for operational and quality concerns.
  • Drive adoption of new processes, systems, or organizational changes. 
  • Provide clear, data driven updates on performance, risks, and mitigation plans.
  • Perform other duties as requested.

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