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Lcms Jobs in Sun Prairie, WI (NOW HIRING)

Method Validation Scientist - II LC-MS

Madison, WI · On-site

  • Medical

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  • PTO

Monday - Friday (Day Shift) Method Validation Scientist II - LCMS Job Responsibilities: * Organize and perform routine to moderate level of method validation/testing (and all associated activities ...

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Lcms information

See Sun Prairie, WI salary details

$136.7K

$206.2K

$230.6K

How much do lcms jobs pay per year?

As of Aug 13, 2026, the average yearly pay for lcms in Sun Prairie, WI is $206,200.00, according to ZipRecruiter salary data. Most workers in this role earn between $199,500.00 and $214,000.00 per year, depending on experience, location, and employer.

What are the key skills and qualifications needed to thrive as an LCMS specialist?

To thrive as an LCMS Specialist, you need a solid background in analytical chemistry, laboratory techniques, and a relevant scientific degree such as chemistry, biochemistry, or a related field. Expertise in operating and troubleshooting LCMS instruments, data analysis software (like MassLynx or Xcalibur), and understanding of regulatory standards is typically required. Attention to detail, problem-solving abilities, and strong communication skills are crucial soft skills in this role. These competencies are essential for ensuring accurate data generation, maintaining instrument performance, and supporting research or quality control objectives.

What are LCMS jobs?

LCMS jobs refer to positions that involve working with Liquid Chromatography-Mass Spectrometry (LC-MS) technology, which is commonly used in analytical chemistry for identifying and quantifying compounds in complex mixtures. Professionals in these roles may operate LC-MS instruments, develop analytical methods, analyze data, and support research or quality control in fields such as pharmaceuticals, environmental science, and food testing. Typical job titles include LCMS Analyst, Scientist, or Technician, and they often require a background in chemistry, biochemistry, or a related field.

What are LCMS jobs?

Liquid chromatography–mass spectrometry (LC-MS or LCMS) is the term for an analytical chemistry technique. Scientists use LC-MS to separate, isolate, and evaluate components of a compound. The duties of people in LC-MS jobs involve using instruments to perform analysis in a laboratory setting. Researchers, R&D scientists, and laboratory technicians use LC-MS techniques to test products in the food, cosmetic, and pharmaceutical industries. Scientists with chemical, agricultural, and biomedical qualifications also use this technique. After collecting data from the LC-MS equipment, your responsibilities include using your scientific skills to interpret your findings and, in some cases, apply the results to product development.

What are some common challenges faced by LCMS analysts and how can they be addressed?

LCMS analysts often encounter challenges such as troubleshooting instrument malfunctions, managing complex sample matrices, and ensuring accurate calibration and maintenance of equipment. Staying current with evolving analytical methods and software updates is essential. Proactively documenting procedures, participating in regular training, and collaborating closely with colleagues in quality control or research teams can help address these challenges and maintain high-quality analytical results.

What is the difference between Lcms vs Laboratory Technician?

AspectLcmsLaboratory Technician
Required CredentialsDegree in Chemistry, Biochemistry, or related field; certification often preferredHigh school diploma or associate degree; technical training
Work EnvironmentAnalytical labs, research facilities, pharmaceutical or environmental labsClinical, industrial, or research laboratories
Job FocusOperating and maintaining liquid chromatography-mass spectrometry equipment, data analysisSample preparation, testing, data recording, basic instrument operation

LCMS specialists focus on operating advanced analytical instruments like liquid chromatography-mass spectrometry, requiring specialized training and certifications. Laboratory Technicians perform broader testing tasks, often with less specialized equipment. While both roles work in laboratory settings, LCMS roles demand more technical expertise in analytical instrumentation, making them more specialized within the lab environment.

What job categories do people searching Lcms jobs in Sun Prairie, WI look for? The top searched job categories for Lcms jobs in Sun Prairie, WI are:
What cities near Sun Prairie, WI are hiring for Lcms jobs? Cities near Sun Prairie, WI with the most Lcms job openings:
Infographic showing various Lcms job openings in Sun Prairie, WI as of August 2026, with employment types broken down into 81% Full Time, 14% Part Time, and 5% Contract. Highlights an 94% In-person, and 6% Remote job distribution, with an average salary of $206,200 per year, or $99.1 per hour.

Associate Manufacturing Scientist I (2nd shift)

Arrowhead Pharmaceuticals

Madison, WI • On-site

$60K - $70K/yr

Full-time, Other

Posted 9 days ago


Job description

Arrowhead Pharmaceuticals, Inc. (Nasdaq ARWR) is a commercial stage biopharmaceutical company that develops medicines that treat intractable diseases by silencing the genes that cause them. Using a broad portfolio of RNA chemistries and efficient modes of delivery, Arrowhead therapies trigger the RNA interference mechanism to induce rapid, deep, and durable knockdown of target genes. RNA interference, or RNAi, is a mechanism present in living cells that inhibits the expression of a specific gene, thereby affecting the production of a specific protein. Arrowhead's RNAi-based therapeutics leverage this natural pathway of gene silencing.

Arrowhead is focused on developing innovative drugs for diseases with a genetic basis, typically characterized by the overproduction of one or more proteins that are involved with disease. The depth and versatility of our RNAi technologies enables us to potentially address conditions in virtually any therapeutic area and pursue disease targets that are not otherwise addressable by small molecules and biologics. Arrowhead is leading the field in bringing the promise of RNAi to address diseases outside of the liver, and our clinical pipeline includes disease targets in the liver and lung with a promising pipeline of preclinical candidates.

Arrowhead's corporate headquarters is in Pasadena, CA with research and development teams in Madison, WI & San Diego, CA, and a state of the art manufacturing facility in Verona, WI. Our employees are nimble, science-driven innovators who are collaborating to bring new therapies to patients in need.

The Position

The Associate Manufacturing Scientist I (second shift) role will involve assisting in the synthesis and subsequent purification steps of large scale oligonucleotides. The operator must comply with GLP/GMP protocols and be able to follow all association SOPs and work instructions when performing and documenting operations.

2nd shift work hours are 1pm – 11:30 pm Monday - Thursday and includes a 10% shift differential.

Responsibilities

  • Follow batch records, SOPs, and work instructions to detail
  • Document all operations in batch records and logbooks
  • Comply with GMP protocols
  • Operate large scale oligonucleotide manufacturing equipment (i.e. oligonucleotide synthesizer, purification skid, tangential flow filtration system, lyophilizer, ChemGlass reactors, pH/conductivity meters, peristaltic pumps, etc.)
  • Assist other chemists within the Manufacturing group during synthesis and purification of oligonucleotides including
    • Reagent solution preparation
    • Mobile phase preparation
    • Column Packing
    • Fraction collection
  • Perform oligonucleotide/intermediate analysis via LCMS
  • Communicate with cross-functional groups such as Process Development, Analytical Development, Quality Control, Quality Assurance, etc.
  • Maintain a clean work space
  • Maintain safety by wearing required personal protective equipment
  • Track and update raw material usage in D365 ERP software
  • Act as production campaign lead
  • Assist with new personnel training

Requirements

  • Bachelor's degree in Chemistry, Biochemistry, Biology, Chemical Engineering, or another scientific discipline or equivalent relevant manufacturing experience.
  • 0–2 years of laboratory or manufacturing experience in biotechnology, pharmaceutical, chemical, or related industries.
  • Ability to follow detailed written procedures and maintain accurate documentation.
  • Strong attention to detail and commitment to quality.
  • Ability to work independently while collaborating effectively within a team.
  • Strong verbal and written communication skills.
  • Demonstrated ability to prioritize work in a fast-paced manufacturing environment.

Preferred

  • Experience working in a GMP-regulated manufacturing or laboratory environment.
  • Hands-on experience with chromatography, filtration, purification, or analytical instrumentation such as LC-MS.
  • Familiarity with manufacturing documentation, batch records, or ERP systems.
Wisconsin pay range
$60,000—$70,000 USD

Arrowhead provides competitive salaries and an excellent benefit package.

Candidates must have current, valid authorization to work in the country where this role is located.

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