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Lcms Jobs in Sun Prairie, WI (NOW HIRING)

Scientist - Analytical Development

Madison, WI · On-site

$77K - $122K/yr

  • Medical

  • Retirement

  • PTO

You will use and troubleshoot HPLC, GC, LCMS, ICPMS, DSC, TGA, KF, FTIR, NMR and XRPD, among other instrumentation, and wet chemical assays. The Analytical Scientist will develop, or direct the ...

Exposure to advanced analytical instrumentation such as UPLC, HPLC, GC, and LCMS * Collaborative and innovative team environment * Chance to develop specialized expertise in food chemistry testing

Associate Analytical Chemist

Madison, WI · On-site

$24.50 - $32.25/hr

We test of a variety of instrumentation including UPLC, HPLC, GC, and LCMS technologies. We offer an innovative and collaborative team environment, and the opportunity to develop expertise on a wide ...

Associate Analytical Chemist

Madison, WI · On-site

$24.50 - $32.25/hr

We test of a variety of instrumentation including UPLC, HPLC, GC, and LCMS technologies. We offer an innovative and collaborative team environment, and the opportunity to develop expertise on a wide ...

Associate Analytical Chemist

Madison, WI · On-site

$24.50 - $32.25/hr

We test of a variety of instrumentation including UPLC, HPLC, GC, and LCMS technologies. We offer an innovative and collaborative team environment, and the opportunity to develop expertise on a wide ...

Associate Analytical Chemist - Any Shift

Madison, WI · On-site

$24.50 - $32.25/hr

We test of a variety of instrumentation including UPLC, HPLC, GC, and LCMS technologies. We offer an innovative and collaborative team environment, and the opportunity to develop expertise on a wide ...

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Lcms information

See Sun Prairie, WI salary details

$136.7K

$206.2K

$230.6K

How much do lcms jobs pay per year?

As of Aug 13, 2026, the average yearly pay for lcms in Sun Prairie, WI is $206,200.00, according to ZipRecruiter salary data. Most workers in this role earn between $199,500.00 and $214,000.00 per year, depending on experience, location, and employer.

What are the key skills and qualifications needed to thrive as an LCMS specialist?

To thrive as an LCMS Specialist, you need a solid background in analytical chemistry, laboratory techniques, and a relevant scientific degree such as chemistry, biochemistry, or a related field. Expertise in operating and troubleshooting LCMS instruments, data analysis software (like MassLynx or Xcalibur), and understanding of regulatory standards is typically required. Attention to detail, problem-solving abilities, and strong communication skills are crucial soft skills in this role. These competencies are essential for ensuring accurate data generation, maintaining instrument performance, and supporting research or quality control objectives.

What are LCMS jobs?

LCMS jobs refer to positions that involve working with Liquid Chromatography-Mass Spectrometry (LC-MS) technology, which is commonly used in analytical chemistry for identifying and quantifying compounds in complex mixtures. Professionals in these roles may operate LC-MS instruments, develop analytical methods, analyze data, and support research or quality control in fields such as pharmaceuticals, environmental science, and food testing. Typical job titles include LCMS Analyst, Scientist, or Technician, and they often require a background in chemistry, biochemistry, or a related field.

What are LCMS jobs?

Liquid chromatography–mass spectrometry (LC-MS or LCMS) is the term for an analytical chemistry technique. Scientists use LC-MS to separate, isolate, and evaluate components of a compound. The duties of people in LC-MS jobs involve using instruments to perform analysis in a laboratory setting. Researchers, R&D scientists, and laboratory technicians use LC-MS techniques to test products in the food, cosmetic, and pharmaceutical industries. Scientists with chemical, agricultural, and biomedical qualifications also use this technique. After collecting data from the LC-MS equipment, your responsibilities include using your scientific skills to interpret your findings and, in some cases, apply the results to product development.

What are some common challenges faced by LCMS analysts and how can they be addressed?

LCMS analysts often encounter challenges such as troubleshooting instrument malfunctions, managing complex sample matrices, and ensuring accurate calibration and maintenance of equipment. Staying current with evolving analytical methods and software updates is essential. Proactively documenting procedures, participating in regular training, and collaborating closely with colleagues in quality control or research teams can help address these challenges and maintain high-quality analytical results.

What is the difference between Lcms vs Laboratory Technician?

AspectLcmsLaboratory Technician
Required CredentialsDegree in Chemistry, Biochemistry, or related field; certification often preferredHigh school diploma or associate degree; technical training
Work EnvironmentAnalytical labs, research facilities, pharmaceutical or environmental labsClinical, industrial, or research laboratories
Job FocusOperating and maintaining liquid chromatography-mass spectrometry equipment, data analysisSample preparation, testing, data recording, basic instrument operation

LCMS specialists focus on operating advanced analytical instruments like liquid chromatography-mass spectrometry, requiring specialized training and certifications. Laboratory Technicians perform broader testing tasks, often with less specialized equipment. While both roles work in laboratory settings, LCMS roles demand more technical expertise in analytical instrumentation, making them more specialized within the lab environment.

What job categories do people searching Lcms jobs in Sun Prairie, WI look for? The top searched job categories for Lcms jobs in Sun Prairie, WI are:
What cities near Sun Prairie, WI are hiring for Lcms jobs? Cities near Sun Prairie, WI with the most Lcms job openings:
Infographic showing various Lcms job openings in Sun Prairie, WI as of August 2026, with employment types broken down into 81% Full Time, 14% Part Time, and 5% Contract. Highlights an 94% In-person, and 6% Remote job distribution, with an average salary of $206,200 per year, or $99.1 per hour.

Associate Scientist III, Quality Control (2nd shift)

Arrowhead Pharmaceuticals

Madison, WI

$80K - $100K/yr

Full-time, Other

Re-posted 19 days ago


Job description

Arrowhead Pharmaceuticals, Inc. (Nasdaq ARWR) is a commercial stage biopharmaceutical company that develops medicines that treat intractable diseases by silencing the genes that cause them. Using a broad portfolio of RNA chemistries and efficient modes of delivery, Arrowhead therapies trigger the RNA interference mechanism to induce rapid, deep, and durable knockdown of target genes. RNA interference, or RNAi, is a mechanism present in living cells that inhibits the expression of a specific gene, thereby affecting the production of a specific protein. Arrowhead's RNAi-based therapeutics leverage this natural pathway of gene silencing.

Arrowhead is focused on developing innovative drugs for diseases with a genetic basis, typically characterized by the overproduction of one or more proteins that are involved with disease. The depth and versatility of our RNAi technologies enables us to potentially address conditions in virtually any therapeutic area and pursue disease targets that are not otherwise addressable by small molecules and biologics. Arrowhead is leading the field in bringing the promise of RNAi to address diseases outside of the liver, and our clinical pipeline includes disease targets in the liver and lung with a promising pipeline of preclinical candidates.

Arrowhead's corporate headquarters is in Pasadena, CA with research and development teams in Madison, WI & San Diego, CA, and a state of the art manufacturing facility in Verona, WI. Our employees are nimble, science-driven innovators who are collaborating to bring new therapies to patients in need.

The Position

This position is within the Quality Control structure, under the Quality Organization. An Associate Scientist III, Quality Control, IPC Testing performs in-process control (IPC) and release testing supporting GMP manufacture of oligonucleotide antisense strand (AS), sense strand (SS), and duplex drug substance (DS), and/or stability sample testing activities for new drug substances and drug products. This role executes analytical testing (e.g., LCMS, HPLC, UV, Karl Fischer, pH, bioburden/endotoxin) during second shift operations, ensuring timely, accurate results are delivered within sample hold times to support real-time batch disposition decisions. This is a hands-on bench role requiring close coordination with Manufacturing personnel across the shift. This position reports to QC Laboratory Management.

2nd shift work hours are 1 pm – 11:30 pm, Monday - Thursday, and includes a 10% shift differential.

Responsibilities

  • Perform IPC sample receipt, preparation, and testing per approved analytical methods and SOPs at each defined IPC sample lane (e.g., crude synthesis pool, post-purification pool, post-UF/DF intermediate, final strand/duplex release)
  • Execute analytical techniques which may include LCMS, AEX and RP-HPLC purity/identity testing, UV (A260) concentration/assay, Karl Fischer water content, pH, and bacterial endotoxin (LAL) testing.
  • Accurately record raw data, calculations, and results in laboratory notebooks, forms, and/or batch records in real time, in compliance with good documentation practices (GDP).
  • Participate in investigations (OOS, OOT, deviations) by providing accurate data, reviewing raw data trends, and executing confirmatory/re-test work as assigned.
  • Monitor and comply with sample hold times; communicate promptly with Manufacturing and QC leadership regarding any hold-time risk, atypical result, or equipment issue that could impact batch progression.
  • Maintain a clean, organized, and compliant lab bench and work area in accordance with GMP, safety, and 5S expectations.
  • Communicate effectively with first-shift QC/Manufacturing staff during shift handoff to ensure continuity of testing and batch status.
  • Ability to work both independently and collaboratively in a dynamic environment
  • Demonstrates enduring flexibility and understanding with changing

Requirements

  • Masters in Chemistry (or related field) with 2+ years' relevant laboratory experience in pharmaceutical/regulated environment or Bachelors in Chemistry (or related field) with 5+ years in a GMP QC or analytical laboratory environment.
  • Strong attention to detail and good documentation practices; comfort working against defined hold times and turnaround targets.
  • Prior experience testing oligonucleotides, peptides, or other synthetic biomolecules.
  • Hands-on experience with LCMS, AEX-HPLC, RP-HPLC/UHPLC, Karl Fischer titration, or LAL/endotoxin testing.
  • Experience supporting in-process (real-time) testing in a manufacturing-adjacent QC lab.
  • Fully knowledgeable of cGMP and ICH laboratory requirements and operations
  • Proficient and demonstrated experience with analytical instrumentation, test methodology/validations/transfers, data acquisition systems, and typical cGMP policies/practices
Wisconsin pay range
$80,000—$100,000 USD

Arrowhead provides competitive salaries and an excellent benefit package.

Candidates must have current, valid authorization to work in the country where this role is located.

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