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Lc Ms Scientist Jobs in Chicago, IL (NOW HIRING)

Medline

Principal Scientist

Mundelein, IL · On-site

$116K - $174K/yr

Job Summary The Principal Scientist is responsible for contributing to the development and support ... Guide and mentor Jr Chemist in the execution of experiments using LC-MS, GC-MS, and ICP-MS ...

Medline

Principal Scientist

Mundelein, IL

$116K - $174K/yr

Job Summary The Principal Scientist is responsible for contributing to the development and support ... Guide and mentor Jr Chemist in the execution of experiments using LC-MS, GC-MS, and ICP-MS ...

Medline

Principal Scientist

Mundelein, IL

$116K - $174K/yr

Job Summary The Principal Scientist is responsible for contributing to the development and support ... Guide and mentor Jr Chemist in the execution of experiments using LC-MS, GC-MS, and ICP-MS ...

Entegris

Research Scientist, Analytical R&D

Aurora, IL · On-site

$105K - $115K/yr

Research Scientist, Analytical R&D The Role: Entegris is currently seeking an Analytical Research ... LC-MS, HPLC, IC, ICP, FTIR, electron microscopy (SEM, TEM, STEM), XRD, XRF, EDX, particle size ...

Fresenius Kabi

Principal Scientist

Melrose Park, IL · On-site

$80K - $95K/yr

... scientific integrity and compliance. Collaborate closely with analytical and formulation teams to ... Hands-on experience operating, maintaining, and troubleshooting GC/MS, HR-LC/MS, ICP-MS, refluxing ...

Freseniusglobal

Principal Scientist

Melrose Park, IL · On-site

$80K - $95K/yr

... scientific integrity and compliance. Collaborate closely with analytical and formulation teams to ... Hands-on experience operating, maintaining, and troubleshooting GC/MS, HR-LC/MS, ICP-MS, refluxing ...

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What are the key skills and qualifications needed to thrive as an LC-MS Scientist, and why are they important?

To excel as an LC-MS Scientist, a strong background in analytical chemistry, experience with liquid chromatography-mass spectrometry (LC-MS), and at least a bachelor's or master's degree in a relevant scientific field are essential. Familiarity with data analysis software (such as MassLynx or Xcalibur), instrument calibration, and method development is typically required. Attention to detail, problem-solving skills, and effective communication help scientists interpret data accurately and collaborate across multidisciplinary teams. These skills are crucial for ensuring high-quality analytical results and supporting research or regulatory compliance in laboratory settings.

What are some common challenges faced by LC-MS Scientists when developing new analytical methods?

LC-MS Scientists often encounter challenges such as matrix effects, where components in the sample interfere with analyte detection, and the need to balance sensitivity with specificity. Method development also requires careful optimization of sample preparation, chromatographic conditions, and mass spectrometer settings to achieve accurate, reliable results. Collaboration with colleagues in sample preparation, data analysis, and quality assurance is key to troubleshooting and refining methods. Staying current with advancements in instrumentation and software can also help overcome technical challenges and improve workflow efficiency.

What are LC-MS scientists?

LC-MS scientists are analytical chemists who specialize in using liquid chromatography-mass spectrometry (LC-MS) techniques to identify, quantify, and analyze chemical compounds in various samples. They play a critical role in fields such as pharmaceuticals, environmental science, food safety, and biotechnology by preparing samples, operating LC-MS instruments, and interpreting complex data. Their work helps ensure product safety, compliance with regulations, and advances in research and development.
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Infographic showing various Lc Ms Scientist job openings in Chicago, IL as of May 2026, with employment types broken down into 3% As Needed, 57% Full Time, 21% Part Time, 1% Temporary, 17% Contract, and 1% Summer. Highlights an 92% Physical, 2% Hybrid, and 6% Remote job distribution.
Principal Scientist

Principal Scientist

Medline

Mundelein, IL • On-site

$116K - $174K/yr

Full-time

Medical, Life, Retirement, PTO

Posted 5 days ago

Medline Industries rating

7.6

Company rating: 7.6 out of 10

Based on 244 frontline employees who took The Breakroom Quiz

216th of 511 rated manufacturers

Job description

Job Summary
The Principal Scientist is responsible for contributing to the development and support of products and technologies within the Chemistry R&D group at Medline. The ideal candidate will greatly contribute to the R&D department with mass spectrometry skills including structural elucidation of unknown compounds for the characterization of plastic packaging systems and medical devices. The Principal Scientist is a subject matter expert in the area of structural elucidation through mass spectrometry and the utilization of pertinent instruments, such as LC-MS, GC-MS and ICP-MS.
Job Description
Responsibilities:
  • Independent, design and execute experiments using various analytical instruments such as liquid chromatography mass spectrometry (LC-MS), gas chromatography mass spectrometry (GC-MS), and inductively coupled plasma mass spectrometry (ICP-MS).
  • Is a leader for the department in the Mass Spectrometry field through innovation.
  • Uses mass spectrometry expertise for structural elucidation of unknown chemical compounds.
  • Facilitate and contribute to Operational Excellence in the Medline Chemistry Department.
  • Author of scientific documents, such as protocols, reports, and analytical methods.
  • Able to effectively communicate and present findings in a concise and organized manner in a form that is suitable for a wide-ranging audience.
  • Performs cross-functional activities to collaborate and communicate with different departments to establish requirements and timeline for project deliverables.
  • Guide and mentor Jr Chemist in the execution of experiments using LC-MS, GC-MS, and ICP-MS instrumentation and structural elucidation.
  • Performs Method Development and Method Validation activities.
  • Able to adapt to changes and has an agile mindset.
  • Demonstrates quality and detail-oriented work.
  • Excellent team player.
Qualifications:
  • Bachelor's degree in chemistry with at least 10+ years of relevant experience, or Master's degree with 8+ years of relevant experience, or Doctorate degree with 5+ years of relevant experience in the mass spectrometry field and unknown structure elucidation.
  • Required knowledge and relevant working experience (hands-on experience) with instrumental analysis including LC-MS, GC-MS, and ICP-MS.
  • Knowledgeable in structural elucidation of unknown chemical compounds through mass spectrometry.
  • Method Development and Method Validation as per FDA and ICH guidelines.
  • Good understanding of GxP practices.
  • Ability to learn quickly and to solve problems in a timely manner using critical thinking and analytical chemistry skills.
  • Able to work in a team environment and demonstrate an inclusive attitude.
  • Possess strong time management and project management skills.
  • Good ability to mentor Jr personnel.

Preferred Qualifications:
  • Subject matter expert in the mass spectrometry field with strong focus on structural elucidation of unknown chemical compounds.
  • Knowledge in the E&L field for medical devices is a plus.

Medline Industries, LP, and its subsidiaries, offer a competitive total rewards package, continuing education & training, and tremendous potential with a growing worldwide organization.
The anticipated salary range for this position:
$116,000.00 - $174,000.00 Annual
The actual salary will vary based on applicant's location, education, experience, skills, and abilities. This role is bonus and/or incentive eligible. Medline will not pay less than the applicable minimum wage or salary threshold.
Our benefit package includes health insurance, life and disability, 401(k) contributions, paid time off, etc., for employees working 30 or more hours per week on average. For a more comprehensive list of our benefits please click here. For roles where employees work less than 30 hours per week, benefits include 401(k) contributions as well as access to the Employee Assistance Program, Employee Resource Groups and the Employee Service Corp.
We're dedicated to creating a Medline where everyone feels they belong and can grow their career. We strive to do this by seeking diversity in all forms, acting inclusively, and ensuring that people have tools and resources to perform at their best. Explore our Belonging page here.
Medline Industries, LP is an equal opportunity employer. Medline evaluates qualified individuals without regard to race, color, religion, gender, gender identity or expression, sexual orientation, national origin, age, disability, neurodivergence, protected veteran status, marital or family status, caregiver responsibilities, genetic information, or any other characteristic protected by applicable federal, state, or local laws.

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About Medline

Sourced by ZipRecruiter

Medline Industries, LP is the leading nationwide supplier of medical, surgical and pharmaceutical products to hospitals, nursing homes, HME providers, surgery centers, physician offices and home care/hospice settings.

Industry

Medical equipment and supplies manufacturing

Company size

10,000+ Employees

Headquarters location

Winnetka, IL, US

Year founded

1966

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