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Laboratory Information System Jobs in Rochester, MN

Mayo Clinic

Histotech Assistant - Histology

Rochester, MN · On-site

$23.29 - $33.36/hr

Subject matter expert of Lab Information System * Record retention * Answering phones Visit the ... Laboratory or leadership experience preferred. * Demonstrated communication, organizational, and ...

Mayo Clinic

Lab Assistant - MCL

Rochester, MN

The laboratory assistant works with various computer information systems on a daily basis. This position is not eligible for visa sponsorship/we will not transfer or sponsor a visa for this position.

Mayo Clinic

Lab Assistant - MCL

Rochester, MN · On-site

The laboratory assistant works with various computer information systems on a daily basis. This position is not eligible for visa sponsorship/we will not transfer or sponsor a visa for this position.

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Laboratory Information System information

See Rochester, MN salary details

$33K

$93.5K

$151.5K

How much do laboratory information system jobs pay per year?

As of Aug 18, 2026, the average yearly pay for laboratory information system in Rochester, MN is $93,477.00, according to ZipRecruiter salary data. Most workers in this role earn between $71,200.00 and $112,800.00 per year, depending on experience, location, and employer.

What is a laboratory information system?

A Laboratory Information System (LIS) is specialized software designed to manage and streamline the operations of a laboratory. It handles functions such as sample tracking, test ordering, results management, workflow automation, and data reporting. LIS enhances efficiency, accuracy, and compliance by integrating with laboratory instruments and other healthcare systems. It is widely used in clinical, research, and industrial labs to support daily operations and regulatory requirements.

What jobs work with a laboratory information system?

Laboratory information system (LIS) jobs involve handling administration and troubleshooting duties for a software system that records, organizes, and stores data from a clinical laboratory. As a LIS specialist or administrator, you install, configure, and manage the laboratory software. Your responsibilities include ensuring that you complete regular system backups, software updates, and data security audits. Some positions involve data entry tasks, such as uploading the results of lab tests. Some LIS specialists or information systems managers train other employees in the use of the system. You can find this job at a large healthcare facility or with an independent clinical lab.

What are the key skills and qualifications needed to thrive as a laboratory information system specialist, and why are they important?

To thrive as a Laboratory Information System (LIS) Specialist, you need a background in laboratory sciences or IT, experience with clinical workflows, and often a degree in medical technology, computer science, or a related field. Familiarity with major LIS platforms (such as Cerner, Epic Beaker, or Sunquest), HL7 interface standards, and relevant certifications like ASCP or LIS-specific credentials are typically required. Strong problem-solving ability, attention to detail, and effective communication skills help you collaborate with laboratory staff and IT teams. These competencies ensure accurate data management, regulatory compliance, and smooth laboratory operations essential to healthcare delivery.

What are some common challenges faced by laboratory information system specialists and how can they be addressed?

LIS specialists often encounter challenges such as integrating new technologies with legacy systems, maintaining data accuracy, and ensuring compliance with healthcare regulations. Working closely with laboratory staff and IT teams is crucial for successful troubleshooting and workflow optimization. Continuous training and staying updated on industry standards help LIS specialists anticipate issues and implement effective solutions, making them valuable contributors to both laboratory efficiency and patient care.

What is the difference between Laboratory Information System vs Laboratory Technician?

AspectLaboratory Information SystemLaboratory Technician
CredentialsTypically requires a degree in health informatics, computer science, or related fieldHigh school diploma or associate degree in laboratory technology
Work EnvironmentSoftware systems in labs, hospitals, or clinicsLaboratory settings performing tests and sample analysis
Employer & IndustryHealthcare, clinical labs, research institutionsMedical laboratories, hospitals, diagnostic centers
Primary FocusManaging lab data, software implementation, and system maintenancePerforming laboratory tests and preparing samples

The Laboratory Information System (LIS) focuses on managing laboratory data and software operations, while the Laboratory Technician handles sample testing and analysis. Both roles are essential in healthcare labs but serve different functions within the laboratory environment.

More about Laboratory Information System jobs

What are popular job titles related to Laboratory Information System jobs in Rochester, MN?

For Laboratory Information System jobs in Rochester, MN, the most frequently searched job titles are:

What job categories do people searching Laboratory Information System jobs in Rochester, MN look for?

The top searched job categories for Laboratory Information System jobs in Rochester, MN are:

What cities near Rochester, MN are hiring for Laboratory Information System jobs?

Cities near Rochester, MN with the most Laboratory Information System job openings:

Laboratory Information System jobs near you
Infographic showing various Laboratory Information System job openings in Rochester, MN as of August 2026, with employment types broken down into 60% Full Time, 20% Part Time, and 20% Contract. Highlights an 100% In-person job distribution, with an average salary of $93,477 per year, or $44.9 per hour.

Histotech Assistant - Histology

Mayo Clinic

Rochester, MN • On-site

Full-time

Medical, Dental, Vision, Retirement

Re-posted 24 days ago

Mayo Clinic rating

7.8

Company rating: 7.8 out of 10

Based on 699 frontline employees who took The Breakroom Quiz

127th of 888 rated healthcare providers

Job description


As a Histotech Assistant working in the Histology Laboratory, you will be responsible for contributing to diagnosis, treatment, and care of patients by performing a volume and variety of Histopathology technical procedures as trained under direct supervision including embedding of tissue blocks and performing microtomy.
Additional responsibilities include:
  • Retrieval and verification of patient samples
  • Tracking specimens
  • Accessioning
  • Specimen photography
  • Processing tissue specimens using various protocols
  • Maintaining laboratory equipment
  • Performing Hematoxylin and Eosin staining
  • Performing coverslipping techniques
  • Performing case assembly and distribution
  • Handling outside/consultation material
  • Troubleshooting equipment, reagent, and case issues
  • Reagent preparation
  • Reviewing pending list/logs
  • Filing and retrieving tissue blocks and slides
  • Handling/disposal of hazardous chemicals
  • Subject matter expert of Lab Information System
  • Record retention
  • Answering phones

Visit the Clinical Labs career site to watch a brief video of Olyvia discussing her role as a Histotech Assistant at Mayo Clinic.
*This position does not typically meet ASCP Board of Certification Route 2 eligibility requirements for Histology Technician Examination.
*Individuals hired to this position are required to complete 2 years in this position before becoming eligible to apply to other positions within Mayo Clinic.
**This position is not eligible for visa sponsorship; Also, Mayo Clinic DOES NOT participate in the F-1 STEM OPT extension program.
Qualifications
To be considered for this position, you must have an associate's degree. In lieu of an associate degree, you may be considered if you have a high school diploma or GED and 2 years of relevant/demonstrated experience.
*This is a limited tenure position for a maximum of 3 years. You will be eligible to reduce to 0.5 full-time equivalency (FTE) if accepted into the Mayo Clinic School of Health Sciences (MCSHS) Histology Technician Program. You must work towards completion of MCSHS Histology Technician program prerequisites: https://college.mayo.edu/academics/health-sciences-education/histology-technician-program-arizona-florida-and-minnesota/.
Additional Requirements
  • Medical terminology preferred.
  • Laboratory or leadership experience preferred.
  • Demonstrated communication, organizational, and problem-solving skills.

Application Requirements
*All must be included for your application to be considered:
  • CV/Resume
  • Cover letter
  • NACES detailed international equivalency for foreign degrees.
  • Internal candidates must provide their past three performance appraisals.

**DLMP employees that have been in current lab/position for less than 2 years must attach early release approval from supervisor.
***Non-DLMP internal applicants that have been in their current department/position for less than 1 year must attach early release approval from supervisor.
*International transcript:
  • MUST have a DETAILED equivalency evaluation.
  • MUST show US equivalent degree.

About Us
Why Mayo Clinic
Mayo Clinic is top-ranked in more specialties than any other care provider according to U.S. News & World Report. As we work together to put the needs of the patient first, we are also dedicated to our employees, investing in competitive compensation and comprehensive benefit plans - to take care of you and your family, now and in the future. And with continuing education and advancement opportunities at every turn, you can build a long, successful career with Mayo Clinic.
Benefits Highlights
  • Medical: Multiple plan options.
  • Dental: Delta Dental or reimbursement account for flexible coverage.
  • Vision: Affordable plan with national network.
  • Pre-Tax Savings: HSA and FSAs for eligible expenses.
  • Retirement: Competitive retirement package to secure your future.

About the Team
Just as our reputation has spread beyond our Minnesota roots, so have our locations. Today, our employees are located at our three major campuses in Phoenix/Scottsdale, Arizona, Jacksonville, Florida, Rochester, Minnesota, and at Mayo Clinic Health System campuses throughout Midwestern communities, and at our international locations. Each Mayo Clinic location is a special place where our employees thrive in both their work and personal lives. Learn more about what each unique Mayo Clinic campus has to offer, and where your best fit is.
Equal Opportunity
All qualified applicants will receive consideration for employment without regard to race, color, religion, sex, gender identity, sexual orientation, national origin, protected veteran status or disability status. Learn more about the "EOE is the Law". Mayo Clinic participates in E-Verify and may provide the Social Security Administration and, if necessary, the Department of Homeland Security with information from each new employee's Form I-9 to confirm work authorization.

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About Mayo Clinic

Sourced by ZipRecruiter

Mayo Clinic is the largest integrated, not-for-profit medical group practice in the world. We're building the future, one where the best possible care is available to everyone — and more people can heal at home. Our relentless research turns into earlier diagnoses and new cures. That's how we inspire hope in those who need it most. At Mayo Clinic, experts work together to solve the most challenging unmet needs of patients. Our history of innovation dates back almost 150 years, when brothers Will and Charlie Mayo pioneered an integrated, team-based approach to medicine. Today, that trailblazing spirit drives innovations like Mayo Clinic Platform — which powers new technologies to change how care is delivered to all.

Industry

Hospitals

Company size

10,000+ Employees

Headquarters location

Rochester, MN, US

Year founded

1919

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