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Laboratory Information System Jobs in Colorado (NOW HIRING)

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Laboratory Information System information

See Colorado salary details

$34.2K

$96.7K

$156.7K

How much do laboratory information system jobs pay per year?

As of Aug 15, 2026, the average yearly pay for laboratory information system in Colorado is $96,698.00, according to ZipRecruiter salary data. Most workers in this role earn between $73,600.00 and $116,700.00 per year, depending on experience, location, and employer.

What is a laboratory information system?

A Laboratory Information System (LIS) is specialized software designed to manage and streamline the operations of a laboratory. It handles functions such as sample tracking, test ordering, results management, workflow automation, and data reporting. LIS enhances efficiency, accuracy, and compliance by integrating with laboratory instruments and other healthcare systems. It is widely used in clinical, research, and industrial labs to support daily operations and regulatory requirements.

What are some common challenges faced by laboratory information system specialists and how can they be addressed?

LIS specialists often encounter challenges such as integrating new technologies with legacy systems, maintaining data accuracy, and ensuring compliance with healthcare regulations. Working closely with laboratory staff and IT teams is crucial for successful troubleshooting and workflow optimization. Continuous training and staying updated on industry standards help LIS specialists anticipate issues and implement effective solutions, making them valuable contributors to both laboratory efficiency and patient care.

What is the difference between Laboratory Information System vs Laboratory Technician?

AspectLaboratory Information SystemLaboratory Technician
CredentialsTypically requires a degree in health informatics, computer science, or related fieldHigh school diploma or associate degree in laboratory technology
Work EnvironmentSoftware systems in labs, hospitals, or clinicsLaboratory settings performing tests and sample analysis
Employer & IndustryHealthcare, clinical labs, research institutionsMedical laboratories, hospitals, diagnostic centers
Primary FocusManaging lab data, software implementation, and system maintenancePerforming laboratory tests and preparing samples

The Laboratory Information System (LIS) focuses on managing laboratory data and software operations, while the Laboratory Technician handles sample testing and analysis. Both roles are essential in healthcare labs but serve different functions within the laboratory environment.

What are the key skills and qualifications needed to thrive as a laboratory information system specialist, and why are they important?

To thrive as a Laboratory Information System (LIS) Specialist, you need a background in laboratory sciences or IT, experience with clinical workflows, and often a degree in medical technology, computer science, or a related field. Familiarity with major LIS platforms (such as Cerner, Epic Beaker, or Sunquest), HL7 interface standards, and relevant certifications like ASCP or LIS-specific credentials are typically required. Strong problem-solving ability, attention to detail, and effective communication skills help you collaborate with laboratory staff and IT teams. These competencies ensure accurate data management, regulatory compliance, and smooth laboratory operations essential to healthcare delivery.

What jobs work with a laboratory information system?

Laboratory information system (LIS) jobs involve handling administration and troubleshooting duties for a software system that records, organizes, and stores data from a clinical laboratory. As a LIS specialist or administrator, you install, configure, and manage the laboratory software. Your responsibilities include ensuring that you complete regular system backups, software updates, and data security audits. Some positions involve data entry tasks, such as uploading the results of lab tests. Some LIS specialists or information systems managers train other employees in the use of the system. You can find this job at a large healthcare facility or with an independent clinical lab.

What are the most commonly searched types of Laboratory Information System jobs in Colorado?

The most popular types of Laboratory Information System jobs in Colorado are:

What job categories do people searching Laboratory Information System jobs in Colorado look for?

The top searched job categories for Laboratory Information System jobs in Colorado are:

What cities in Colorado are hiring for Laboratory Information System jobs?

Cities in Colorado with the most Laboratory Information System job openings:

Infographic showing various Laboratory Information System job openings in Colorado as of August 2026, with employment types broken down into 86% Full Time, 5% Part Time, 7% Contract, and 2% Nights. Highlights an 100% In-person job distribution, with an average salary of $96,698 per year, or $46.5 per hour.

Information System Security Officer

MIT Lincoln Laboratory

Colorado Springs, CO • Hybrid

Full-time

Medical, Dental, Vision, Retirement, PTO

Re-posted 25 days ago


Job description

The Security Services Department's overall mission is to identify and counter security threats to the MIT Lincoln Laboratory's mission of development of game-changing technology in support of National Security, including guarding against compromise by foreign intelligence agencies and insider threats. To accomplish this mission, this department formulates and implements policies, plans, and actions designed to protect facilities against threats of vandalism, accidental destruction, and sabotage; and safeguards personnel, classified and unclassified information systems, personal identifiable information, property, and other assets from exploitation and recruitment by foreign intelligence agencies.

We foster a culture where security professionals are empowered to solve complex security problems in close collaboration with Laboratory research teams and Government counterparts. Our people are our most important resource, and we encourage a casual and flexible opportunity-filled working environment that is technology-focused. Where mission needs can be met, the Security Services Department encourages flexible schedules and hybrid remote work arrangements.

Who are we?

 MIT Lincoln Laboratory is a Federally Funded Research and Development Center (FFRDC) whose mission is research in support of National Security.
* Mission - The Security Services Department's (SSD) overall mission is to identify and counter security threats to the MIT Lincoln Laboratory's (MIT LL) mission of development of game-changing technology in support of national security, including guarding against compromise by foreign intelligence agencies and insider threats.
* Culture - We foster an inclusive, opportunity-filled environment of empowered team members from diverse backgrounds.

What will you do?

Provide information systems security support to several independent MITLL Special programs.  

Core responsibilities include:

  • Assist and Support necessary compliance activities (e.g., ensure that cyber system security configurations guidelines are followed, compliance monitoring occurs).
  • Continuously validate the organization against cybersecurity policies/guidelines/procedures/regulations/laws to ensure compliance.
  • Ensure that plans of actions and milestones or remediation plans are in place for vulnerabilities identified during risk assessments, audits, inspections, etc.
  • Promote awareness of security issues among management and ensure sound security principles are reflected in the organization's vision and goals.
  • Conduct continuous monitoring and track audit findings and provide countermeasure and mitigation recommendations to ensure that appropriate actions are taken to secure critical R & D data.
  • Recommend resource allocations required to securely operate and maintain an organization's cybersecurity requirements.
  • Provide technical documents, incident reports, findings from computer examinations, summaries, and other situational awareness information to key stake holders.
  • Recognize a possible security violation and take appropriate action to report the incident, as required.
  • Assist the Program Managers and the Information System Security Manager (ISSM) in the development and maintenance of System Security Plans (SSP) and associated artifacts such as the Plan of Action & Milestones (POA&M), Risk Assessment Report, and Continuous Monitoring Strategy.
  • Ensure systems are operated, maintained, and disposed of in accordance with organization security policies and procedures.
  • Provide periodic cybersecurity reviews of network, system, and application vulnerability scanning, configuration assessment, and remediation.
  • Lead and align information technology (IT) security priorities with the security strategy.
  • Prepare for and participate in periodic organization compliance assessments.
  • Interpret patterns of noncompliance to determine their impact on levels of risk and/or overall effectiveness of the enterprise's cybersecurity program.
How will you grow?

You will find significant opportunities to do meaningful work in an environment intentionally designed to be one where you will learn, thrive and belong.

  • Leadership: Room to advance on your team or to lead cross-functional projects.
  • Growth Opportunities: Potential for lateral and vertical movement.
  • Education/Training: Management training, mentorship, in-house and external courses.
  • Exposure: Engagement with sponsors, stakeholders, Laboratory leadership and other Departments and Divisions.
  • Community: Participation is encouraged for Laboratory social events, Employee Resource Groups (ERGs), clubs and study groups, volunteering and community service projects.
What you need/Requirements:

To work with MIT LL, all employees must meet certain basic requirements.

  • A current Top Secret Clearance with SCI eligibility
  • Must be a U.S. Citizen.
  • Successfully pass a background check and consent to undergoing a government polygraph examination.
  • Demonstrated experience with vulnerability scanning and auditing tools and processes is required 
  • Excellent written and verbal communication skills are required
  • Demonstrated understanding of the following security frameworks is required:
    • NIST 800-53 / Risk Management Framework (RMF)
    • Intelligence Community Directive (ICD) 503
    • National Industrial Security Program Operating Manual (NISPOM) Chapter 8
    • DoD Manual 5205.07 Volumes 1- 4
Requirements - Ideally, you will have:

The Laboratory values experiences from diverse backgrounds and occupations. The most successful candidates will have the following skills and qualifications.

  • A minimum of 4 years of IT security experience in DoD cybersecurity is preferred
  • Possess a DoD 8570.01-M IAM I baseline certification (e.g. CompTIA Security+), or be able to obtain one within 6 months of hire
  • Technical experience, skills, and course work completed towards an undergraduate degree, or industry IT certifications may be considered in lieu of education or DoD security experience requirements
  • Experienced in auditing, configuration and vulnerability management
  • Experience and familiarity with multiple operating systems such as Windows Server 2012, 2016, 2019, and 2022 Windows 10 and 11, Red Hat Enterprise Linux, Ubuntu, Mac, etc.
  • Experience with virtualization and Cloud technologies is preferred
  • Ability to integrate information security requirements into the acquisition process; using applicable baseline security controls as one of the sources for security requirements; ensuring a robust software quality control process; and establishing multiple sources (e.g., delivery routes, for critical system elements).
  • Technical experience securing networks and systems utilizing DISA STIGs and/or SRGs is highly desired

Hiring Range: $78,300 - $102,000

 

Disclaimer: MIT Lincoln Laboratory provides a typical hiring range as a good faith estimate of what we reasonably expect to offer for this position at the time of posting. The final salary offered to a selected candidate will depend on various factors, including-but not limited to-the scope and responsibilities of the role, the candidate's experience, skills and education/training, internal equity considerations and applicable legal requirements. This range reflects base salary only and does not include additional forms of compensation or benefits.

At MIT Lincoln Laboratory, our exceptional career opportunities include many outstanding benefits to help you stay healthy, feel supported, and enjoy a fulfilling work-life balance. Benefits offered to employees include: 

  • Comprehensive health, dental, and vision plans
  • MIT-funded pension
  • Matching 401K
  • Paid leave (including vacation, sick, parental, military, etc.)
  • Tuition reimbursement and continuing education programs
  • Mentorship programs
  • A range of work-life balance options
  • ... and much more!  

Please visit our Benefits page for more information. As an employee of MIT, you can also take advantage of other voluntary benefits, discounts and perks.

Selected candidate will be subject to a pre-employment background investigation and must be able to obtain and maintain a Secret level DoD security clearance.

MIT Lincoln Laboratory is an Equal Employment Opportunity (EEO) employer. All qualified applicants will receive consideration for employment and will not be discriminated against on the basis of race, color, religion, sex, sexual orientation, gender identity, national origin, age, veteran status, disability status, or genetic information; U.S. citizenship is required.

Requisition ID: 42841 

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