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Interstate Jobs in Missouri (NOW HIRING)

Marten Transport

CDL-A Truck Driver

Saint Peters, MO · On-site

$54K - $96K/yr

Top Pay Without the Typical Reefer Headaches - Earn $54,600 - $96,000 per Year* Applicants must have a current Interstate Commercial Driver's License (Class A). Applicants must have a minimum of 6 ...

SCP Health

Emergency Medicine Physician

Sikeston, MO · On-site

$50K/yr

Sikeston is located on Interstate 55 and Interstate 57/US Highway 60, and is less than 1.5 hours from the Arkansas and Kentucky borders Benefits & Compensation No Non-Compete • Competitive ...

SCP Health

Emergency Medicine Physician

Sikeston, MO · On-site

$50K/yr

Sikeston is located on Interstate 55 and Interstate 57/US Highway 60, and is less than 1.5 hours from the Arkansas and Kentucky borders Benefits & Compensation No Non-Compete • Competitive ...

CompHealth

OB-GYN Physician Needed in Missouri

Lebanon, MO · On-site

$350K - $375K/yr

Come practice in Lebanon, conveniently located directly on Interstate 44 and positioned perfectly in the scenic Ozarks of south-central Missouri. The Lebanon and Laclede County Area offers a wide ...

CompHealth

OB/GYN job in Lebanon MO

Lebanon, MO

Come practice in Lebanon, conveniently located directly on Interstate 44 and positioned perfectly in the scenic Ozarks of south-central Missouri. The Lebanon and Laclede County Area offers a wide ...

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Showing results 41-60

All JobsInterstate JobsInterstate Jobs in Missouri

Interstate information

See Missouri salary details

$15

$20

$27

How much do interstate jobs pay per hour?

As of Aug 18, 2026, the average hourly pay for interstate in Missouri is $20.61, according to ZipRecruiter salary data. Most workers in this role earn between $17.36 and $24.81 per hour, depending on experience, location, and employer.

What is an interstate job?

Interstate jobs typically refer to employment opportunities that involve working across state lines or require travel between different states. These positions can include truck drivers, sales representatives, or service technicians whose work takes them from one state to another. Interstate jobs may require special licenses or certifications, such as a commercial driver's license (CDL), and adherence to federal and state regulations. Working in an interstate role can offer variety and higher earning potential, but it may also involve extended time away from home.

What are the key skills and qualifications needed to thrive as an interstate truck driver?

To thrive as an Interstate Truck Driver, you need a valid Commercial Driver’s License (CDL), knowledge of DOT regulations, and a solid driving record. Familiarity with GPS navigation systems, electronic logging devices (ELDs), and truck maintenance tools is crucial. Strong time management, attention to detail, and communication skills help drivers navigate schedules and coordinate effectively. These competencies ensure safe, timely deliveries and compliance with federal transportation laws in a demanding environment.

What are common challenges faced by professionals working in interstate logistics roles, and how can they be managed?

Professionals in interstate logistics often encounter challenges such as coordinating shipments across state lines, managing compliance with varying state regulations, and handling unexpected delays due to weather or transportation issues. Successful management involves strong communication skills, thorough documentation, and the use of advanced logistics software to track shipments and ensure regulatory compliance. Building strong relationships with carriers and being adaptable to changing circumstances also help in overcoming these common hurdles.

What is the difference between Interstate vs Truck Driver?

AspectInterstateTruck Driver
CredentialsCommercial Driver's License (CDL)Commercial Driver's License (CDL)
Work EnvironmentLong-haul, across state linesLocal, regional, or long-haul routes
Industry UsageFreight, logistics, transportationFreight, logistics, transportation
Search IntentInterstate trucking jobsTruck driving jobs

Interstate drivers specifically operate trucks across state lines, often involving long-distance travel. Truck drivers may work locally or regionally but can also operate interstate routes. Both roles require a CDL and are integral to the transportation industry, but 'Interstate' emphasizes cross-state routes, while 'Truck Driver' is a broader term encompassing all driving roles in trucking.

What cities in Missouri are hiring for Interstate jobs?

Cities in Missouri with the most Interstate job openings:

Interstate jobs near you
Infographic showing various Interstate job openings in Missouri as of August 2026, with employment types broken down into 1% Locum Tenens, 1% As Needed, 88% Full Time, 7% Part Time, and 3% Contract. Highlights an 97% Physical, 1% Hybrid, and 2% Remote job distribution, with an average salary of $42,878 per year, or $20.6 per hour.

Mover / Laborer - St. Charles

TWO MEN AND A TRUCK®

Saint Charles, MO

$17/hr

Full-time

Medical, Dental, Vision, Retirement, PTO

Re-posted 16 days ago

Two Men and a Truck rating

4.8

Company rating: 4.8 out of 10

Based on 78 frontline employees who took The Breakroom Quiz

21st of 29 rated removal and storage companies

Job description

HIRING IMMEDIATELY – MOVERS / LABORERS!
**ONSITE JOB OFFERS!!!**
PAY!
  • MOVERS EARN $17 PER HOUR PLUS TIPS!
  • TIPS earned daily! (top performers average $300 - $500 per week!)
  • Guaranteed 2 days off per week! (Closed on Sunday’s)
  • Weekly pay via direct deposit
  • Benefits: medical, vision, dental, 401(k), Paid Time Off
  • Earn up to 2 weeks of EXTRA vacation time for perfect attendance!
  • Paid, hands-on training and career development
PERKS!
  • NEW branded 26 ft. Box Trucks – All Automatic Transmission
  • Tablets for electronic paperwork and payments
  • Work locally – be home every night!
  • Work with a regular team – no day labor
  • Flexible hours
  • **OPTIONAL** Interstate Travel
REQUIREMENTS
  • Must be 18 years or older
  • Ability to lift heavy items (100 lbs. or more)
TWO MEN AND A TRUCK® St. Louis is urgently hiring and looking for multiple movers and drivers to join our team! Experience in general labor, construction, warehouse labor, manufacturing, or truck driving helpful! TWO MEN AND A TRUCK® St. Louis - check our team out on Facebook!
This job posting is for a position at the individually owned and operated TWO MEN AND A TRUCK® franchise located in St. Peters, Missouri. The employer at this location is J amp; C Enterprises, Inc.

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