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Internship Downstream Process Development Jobs in California

Apple

Memory Packaging Engineer

Santa Clara, CA · On-site

In this role, you will drive the definition, development, and qualification of next-generation ... Solid working experience in package test and reliability, system-level downstream process ...

Apple

Memory Packaging Engineer

Santa Clara, CA · On-site

In this role, you will drive the definition, development, and qualification of next-generation ... Solid working experience in package test and reliability, system-level downstream process ...

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All JobsInternship Downstream Process Development JobsInternship Downstream Process Development Jobs in California

Internship Downstream Process Development information

What is the difference between Internship Downstream Process Development vs Downstream Process Technician?

AspectInternship Downstream Process DevelopmentDownstream Process Technician
CredentialsTypically pursuing or holding a degree in biotech, chemistry, or related fieldsUsually requires technical diploma or associate degree in biotech or related areas
Work EnvironmentLaboratory and development settings, focusing on process optimization and experimental workManufacturing floor, operating equipment, and performing process runs
ResponsibilitiesAssisting in process development, data analysis, and protocol documentationExecuting downstream processing steps, equipment setup, and process monitoring

In summary, Internship Downstream Process Development focuses on learning and supporting process optimization in a lab setting, while Downstream Process Technicians handle the hands-on execution of downstream manufacturing processes in production environments.

What are the key skills and qualifications needed to thrive as an Internship Downstream Process Development, and why are they important?

To thrive in an Internship Downstream Process Development role, a solid background in biotechnology, chemical engineering, or a related field, along with foundational lab skills, is essential. Familiarity with bioprocessing techniques, analytical instruments, and data analysis software is typically required, and experience with GMP environments can be advantageous. Strong problem-solving abilities, attention to detail, and effective communication are important soft skills for collaborating with team members and documenting results. These competencies ensure interns can contribute to optimizing purification processes and maintaining high standards in biopharmaceutical development.

What types of hands-on projects can I expect to work on during an Internship in Downstream Process Development?

As an intern in Downstream Process Development, you will typically assist with projects focused on purification and recovery of biological products, such as proteins or antibodies, from complex mixtures. This often includes tasks like preparing chromatography columns, performing filtration techniques, and conducting sample analysis using methods such as SDS-PAGE or HPLC. You’ll also collaborate closely with experienced scientists and engineers, participate in team meetings to review data, and help troubleshoot process challenges. These experiences provide valuable insight into both laboratory workflows and the broader bioprocess development pipeline.

What is an Internship in Downstream Process Development?

An Internship in Downstream Process Development is a temporary position, typically for students or recent graduates, focused on learning and supporting the processes involved in purifying and formulating biopharmaceutical products after the initial production stage. Interns in this field gain hands-on experience with techniques such as filtration, chromatography, and quality control, and often work within a research and development or manufacturing environment. This internship helps build skills in laboratory methods, data analysis, and process optimization, making it valuable for those interested in careers in biotechnology or pharmaceuticals.
What are the most commonly searched types of Downstream Process Development jobs in California? The most popular types of Downstream Process Development jobs in California are:
What cities in California are hiring for Internship Downstream Process Development jobs? Cities in California with the most Internship Downstream Process Development job openings:
Internship Downstream Process Development jobs near you
Infographic showing various Internship Downstream Process Development job openings in California as of June 2026, with employment types broken down into 8% Internship, 84% Full Time, and 8% Contract. Highlights an 92% In-person, and 8% Remote job distribution.
Associate Scientist (BS/MS) contractor - Lentiviral Vector Research & Early Process Development (...

Associate Scientist (BS/MS) contractor - Lentiviral Vector Research & Early Process Development (...

Adicet Bio

Redwood City, CA

Other

Posted 15 days ago

Job description

Associate Scientist (BS/MS) contractor - Lentiviral Vector Research & Early Process Development (100% Bench)

Contract Duration: One year

Why this matters:

This role accelerates cell and genome therapy research by enabling reliable generation, characterization, and improvement of lentiviral vectors used in discovery and preclinical studies.

The Opportunity

We are seeking a highly motivated Senior Research Associate / Associate Scientist (BS/MS) to advance lentiviral vector research with some early process development. This is a 100% bench-based, hands-on laboratory role focused on running, troubleshooting, and improving upstream and downstream LVV workflows to enable discovery and preclinical studies.

Key Responsibilities

  • Scope note: this is a hands-on lab role and is not primarily computational, project-management, or supervisory.
  • Design and execute iterative LVV experiments in adherent and/or suspension HEK293T-based systems (cell expansion, transfection, harvest, and in-process sampling) to evaluate and improve performance.
  • Execute and optimize downstream processing, including clarification/filtration and concentration/buffer exchange using TFF/UF-DF; assess recovery, scalability, and robustness.
  • Support early scale-up/scale-down studies (e.g., shake flasks, cell factories, wave or single-use stirred-tank bioreactors), including setup, sterile connections, sampling plans, and data-driven comparisons across scales.
  • Quantify and interpret vector yield and quality using standard assays (e.g., qPCR/ddPCR titers, p24/ELISA, infectivity/functional readouts as applicable); communicate findings, hypotheses, and recommended next experiments.
  • Maintain rigorous documentation in an electronic lab notebook (ELN) and author/refresh protocols and SOPs that improve reproducibility, safety, and throughput for R&D and early PD workflows.
  • Collaborate with scientists to prioritize experiments, troubleshoot process/assay issues, and ensure safe handling of viral vectors and human-derived materials in accordance with BSL-2/EHS requirements.

Qualifications

  • Minimum Qualifications
    • B.S. with 4+ years, or M.S. with 2+ years of relevant industry or academic experience in molecular biology, bioengineering, cell biology, biochemistry, or related field.
    • Demonstrated hands-on experience producing and concentrating viral vectors and/or biologics; familiarity with at least one downstream method (TFF/UF-DF, chromatography, or ultracentrifugation).
    • Expertise in mammalian cell culture (aseptic technique, cell counting/viability, expansion, banking) with comfort working in BSL-2 environments.
    • Ability to execute experiments with minimal supervision, troubleshoot process/assay issues, and communicate results clearly in a fast-paced R&D environment.
    • Must be comfortable spending the majority of work time performing hands-on, bench-level laboratory work (e.g., tissue culture, transfection, purification/TFF, and assays).
    • Strong documentation skills using ELNs (e.g., Benchling) and proficiency with standard data tools (Excel/GraphPad or equivalent).
    • Able to work effectively both independently and collaboratively, with strong planning, organization, and cross-functional communication.
  • Preferred Qualifications
    • Experience with scalable unit operations for viral vector production (single-use stirred-tank or wave bioreactors, cell factories, TFF/UF-DF) and associated sampling/monitoring.

This role is open to individual contractors only. Recruitment agencies: please do not contact us or submit candidates.

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