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Intern Downstream Processing Scientist Jobs (NOW HIRING)

Lonza

Scientist II, Downstream

Houston, TX

Scientist II, Downstream Location: This is an on-site position located in Pearland, TX. The purpose ... The ideal candidate will be responsible for leading new process development and improving existing ...

Lonza

Scientist II, Downstream

Houston, TX · On-site

Scientist II, Downstream Location: This is an on-site position located in Pearland, TX. The purpose ... The ideal candidate will be responsible for leading new process development and improving existing ...

Kinetic Personnel Group

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Supervisor, Manufacturing - Downstream

Irvine, CA · On-site

$75K - $95K/yr

Perform hands-on purification processes, including column chromatography, tangential flow ... Bachelor's degree in life sciences or a closely related discipline * Demonstrated leadership in ...

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CEDENT

Senior Scientist, Process Development

Watertown, MA

$99K - $135K/yr

... downstream processing, analyzing data, and contributing to process development projects. The ideal candidate will be involved in troubleshooting complex issues. The position requires a strong ...

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Intern Downstream Processing Scientist information

What is the difference between Intern Downstream Processing Scientist vs Intern Upstream Processing Scientist?

AspectIntern Downstream Processing ScientistIntern Upstream Processing Scientist
CredentialsTypically pursuing or holding a degree in Biotechnology, Biochemistry, or related fieldsSame as downstream role, often with focus on bioprocessing or molecular biology
Work EnvironmentLaboratories, manufacturing facilities, quality control labsLaboratories, bioreactors, research and development settings
Industry UsagePharmaceutical, biotech, and bioprocessing companiesSame industries, focusing on different stages of bioprocessing

Both roles involve working in biotech and pharmaceutical settings, with similar educational backgrounds. The main difference is the focus: downstream processing scientists handle purification and formulation, while upstream processing scientists focus on cell culture and bioreactor operations. Interns in both roles gain hands-on experience in bioprocessing, but their specific tasks differ according to the stage of production.

What cities are hiring for Intern Downstream Processing Scientist jobs? Cities with the most Intern Downstream Processing Scientist job openings:
What are the most commonly searched types of Downstream Processing Scientist jobs? The most popular types of Downstream Processing Scientist jobs are:
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Intern Downstream Processing Scientist jobs near you
Infographic showing various Intern Downstream Processing Scientist job openings in the United States as of June 2026, with employment types broken down into 99% Full Time, and 1% Nights. Highlights an 85% Physical, 4% Hybrid, and 11% Remote job distribution.

Associate Scientist, Downstream Process Development

Epicrispr Biotechnologies

South San Francisco, CA

$118K - $124K/yr

Other

Posted 6 days ago

Job description

Title: Associate Scientist, Downstream Process Development

Location: South San Francisco, CA

Opportunity:

We are seeking a highly motivated and detail-oriented Associate Scientist to join the Downstream Process Development team focused on adeno-associated virus (AAV) gene therapy therapeutics. This role will support the development, optimization, and scale-up of purification processes for AAV vectors from early research through clinical manufacturing.

Responsibilities:

  • Design, execute, and analyze downstream purification experiments for AAV vectors for process steps including clarification, sterile filtration, tangential flow filtration (TFF), chromatography (affinity, ion exchange, size exclusion, mixed mode), and ultracentrifugation.
  • Perform small-scale studies for development of downstream AAV processes, process optimization, process characterization, and assessment of process robustness.
  • Support process development activities from bench scale through pilot scale and tech transfer to GMP manufacturing.
  • Present data and project updates in team meetings and cross-functional forums.
  • Maintain accurate and timely documentation in electronic lab notebooks and technical reports.
  • Collaborate cross-functionally with upstream process development and analytical development and other functions.
  • Stay current with advancements in AAV purification technologies, regulatory expectations, and industry best practices.

Qualifications:
The requirements listed below are representative of the knowledge, skill, and/or ability required to perform this job successfully.

  • B.S. degree in Biochemical Engineering, Chemical Engineering, Molecular Biology, Biotechnology, Biochemistry, or related discipline with 5+ years of relevant industry experience (or M.S. with 3+ years or Ph.D.)
  • Required experience with AKTA purification
  • Strong working knowledge of chromatography and filtration technologies
  • Hands-on experience with viral vector purification, preferably AAV
  • Experience with analytical techniques for AAV characterization such as Refeyn, qPCR/dPCR/ddPCR, ELISA, alkaline gel, CE-SDS, SEC-HPLC, AUC and other similar analytical assays
  • Familiarity with Design of Experiments (DOE) and JMP are a plus
  • Strong organizational, analytical, and problem-solving skills
  • Excellent written and verbal communication skills

Compensation: The salary range for this position is $118,000 to $124,000 USD annually. This salary range is an estimate, and the actual salary may vary based on various factors, including, without limitation, individual education, experience, tenure, skills, and abilities, as well as internal equity and alignment with market data, including potential adjustments for geographic location. 

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