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Department:SOM KC Department of Microbiology, Molecular Genetic and Immunology

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Tse LabPosition Title:Post-Doc Fellow - Tse LabJob Family Group: Professional StaffJob Description Summary:A postdoctoral position is available in the laboratory of Dr. Hubert Tse in the Department of Microbiology, Molecular Genetics, and Immunology at the University of Kansas Medical Center. Our research program seeks to increase our understanding of the immunological and molecular mechanisms involved in autoimmune dysregulation in Type 1 diabetes (T1D). Through the use of novel murine models of T1D, human translational studies, and innovative technologies including spatial transcriptomics, single cell RNA-sequencing, and induced-pluripotent stem cells, we are interested in determining how reactive oxygen species (ROS) synthesis contributes to innate immune responses and autoreactive T cell effector mechanisms involved in pancreatic -cell destruction. Additional research projects in the lab include the use of novel immunoprotection strategies to delay islet transplantation rejection and to define the role of insulin-producing -cells in T1D. We seek a motivated, creative, and energetic applicant with excellent communication skills and organization. The laboratory uses immunological methods, molecular biology, cellular biochemistry, redox biology, murine models, imaging, and flow cytometry to discover and evaluate new mechanisms of autoimmune dysregulation. If interested, please send a letter describing your research experience/interest/future career aspirations, your CV, and contact information for three references.Job Description:

Key Roles and Responsibilities:

• Conduct mentored research in induced-pluripotent stem cell-derived macrophages to examine their ability to delay autoimmune responses. Perform spatial transcriptomics to increase our understanding of the role of b-cells in Type 1 diabetes.

• Perform data analysis, prepare data for presentations (oral and written), write manuscripts and other research documents.

Compliance: Attend and maintain compliance on all orientation and training sessions designated by the University and the Department of Microbiology, understand and follow all assigned duties, and attend regularly scheduled research team meetings.

Postdoc Expectations: The Postdoc will be expected to complete research projects under the guidance of the faculty mentor, record and interpret the results of their experiments in an (electronic) laboratory notebook, prepare publication-quality manuscripts (including figures and tables) and publish in peer-reviewed literature.

• Read literature articles, develop new ideas, and assimilate the information into his/her project design/interpretation.

• Dissemination of studies: Interact on a regular basis with their faculty mentor and members of the laboratory to discuss experimental design and interpretation of results.

• Present research aims and findings at department seminars and at scientific meetings. Write and publish their results as first author in abstracts, manuscripts, and posters.

• Submit fellowship applications, as eligible, to bolster research funding and CV building for projects.

Work Environment

Work is normally performed in a typical interior work environment which does not usually subject the employee to any unpleasant elements.

This job description is not designed to cover or contain a comprehensive listing of activities, duties or responsibilities that are required of the employee for this job. It is only a summary of the typical functions of the job, not an exhaustive list of all possible job responsibilities, tasks, duties, and assignments. Furthermore, job duties, responsibilities and activities may change at any time with or without notice.

Required Qualifications:

• Education: PhD in Microbiology, Immunology, Biochemistry, Molecular Biology, or related field.

• Work Experience: 4 years related research experience.

This position requires a formal degree in the cited discipline area(s) to ensure that candidates have the foundational knowledge and skill set required to perform the duties of the position. The level of degree is based on accreditation requirements, institutional standards of academic and professional excellence, alignment with peer institution benchmarks, and contributes to the credibility and effectiveness of the role within the university community.

Required Documents:

• Resume/CV

• Cover Letter

Comprehensive Benefits Package:

Employee Type: RegularTime Type: Full timeRate Type: Salary

Compensation Statement:

The pay range listed for this position is determined by our compensation program using market data and salary benchmarking. A combination of factors is considered in making compensation decisions including, but not limited to, education, experience and training, qualifications relative to the requirements of the position, and funding. At the University of Kansas Medical Center, a reasonable estimate for the starting pay range will be the minimum to midpoint of the posted range, taking into account the combination of factors listed above.

Pay Range:$63,480.00 - $90,000.00

Minimum

$63,480.00

Midpoint

$76,739.00

Maximum

$90,000.00