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Instrumentation Software Engineer Jobs in California

Software Engineer

Emeryville, CA · On-site

$120K - $150K/yr

Software Engineer Position Description: Protingent Staffing has an exciting direct hire Software ... and instrumentation architecture * Maintain clear technical documentation for all systems ...

Controls Software Engineer

Bodega Bay, CA

$53.75 - $68.50/hr

... facilities and scientific instrumentation. The engineer will work primarily with EPICS ... Design, maintain, and deploy software using modern unit testing and deployment techniques.

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Software Engineer

San Jose, CA · On-site

$125K - $150K/yr

  • Medical

  • Dental

  • Vision

  • Life

  • Retirement

  • PTO

Bachelor's degree in software engineering, Electrical Engineering, Physics, or a related discipline. * 2 - 5 years of experience developing software preferably for scientific instrumentation or test ...

They are seeking a versatile Ground Segment Software Engineer to build robust ground segment ... to the instrumentation and optimization of satellite communication flowgraphs. • Ensure ...

Software Engineer (Components)

Hawthorne, CA

$145K - $175K/yr

  • Medical

  • Dental

  • Vision

  • Life

  • Retirement

  • PTO

Write automation software to interact with flight hardware, test equipment, instrumentation, and production documentation systems * Develop custom automation solutions to engineering and ...

Software Engineer (Components)

Hawthorne, CA · On-site

$145K - $175K/yr

  • Medical

  • Dental

  • Vision

  • Life

  • Retirement

  • PTO

Write automation software to interact with flight hardware, test equipment, instrumentation, and production documentation systems * Develop custom automation solutions to engineering and ...

Software Engineer (Components)

Hawthorne, CA · On-site

$145K - $175K/yr

  • Medical

  • Dental

  • Vision

  • Life

  • Retirement

  • PTO

Write automation software to interact with flight hardware, test equipment, instrumentation, and production documentation systems * Develop custom automation solutions to engineering and ...

Software Engineer

San Diego, CA · On-site

$109K - $171K/yr

Our Software Engineering (R&D) department is looking for a Software Engineer here in San Diego ... multiple instrumentation platforms (Panther System, Panther Fusion System) and a menu of assays ...

Improve data flows, instrumentation, and operational visibility across the funnel * Move quickly ... Strong software engineering fundamentals and ability to write production-level code * Full-stack ...

Our Software Engineering (R&D) department is looking for a Software Engineer here in San Diego ... multiple instrumentation platforms (Panther System, Panther Fusion System) and a menu of assays ...

Systems Software Engineer

Santa Clara, CA · On-site

$120K - $130K/yr

  • Medical

  • Dental

  • Vision

  • Life

  • Retirement

  • PTO

Systems Engineer - Firmware & Instrument Control Company: Picarro Location: Santa Clara, CA ... Develop control interfaces for laser-based experimental instrumentation systems * Integrate and ...

Systems Software Engineer

Santa Clara, CA · On-site

$120K - $130K/yr

  • Medical

  • Dental

  • Vision

  • Life

  • Retirement

  • PTO

Systems Engineer - Firmware & Instrument Control Company: Picarro Location: Santa Clara, CA ... Develop control interfaces for laser-based experimental instrumentation systems * Integrate and ...

They are seeking a versatile Ground Segment Software Engineer to build robust ground segment ... to the instrumentation and optimization of satellite communication flowgraphs. • Ensure ...

... and instrumentation implementation. • Addressing customer issues in current systems ... software to accelerate innovation in the engineering design of silicon to systems. Founded in 1988 ...

R&D Software Engineer

Santa Clara, CA · On-site

  • Medical

  • Dental

  • Vision

  • Life

  • Retirement

  • PTO

Responsibilities This position offers a unique and high-impact opportunity for a software engineer ... Prior internship, co-op, or project experience supporting manufacturing, metrology, instrumentation ...

Senior Staff Software Engineer

Santa Clara, CA · On-site

$200K - $220K/yr

  • Medical

  • Dental

  • Vision

  • Life

  • Retirement

  • PTO

Senior Staff Software Engineer Location: Santa Clara, CA (Onsite) Group: Analyzer Product Group ... instrumentation. In this role, you'll serve as a hands-on technical leader-defining system ...

Showing results 21-40

Instrumentation Software Engineer information

See California salary details

$60.2K

$111.9K

$167.5K

How much do instrumentation software engineer jobs pay per year?

As of Aug 13, 2026, the average yearly pay for instrumentation software engineer in California is $111,898.00, according to ZipRecruiter salary data. Most workers in this role earn between $87,700.00 and $132,300.00 per year, depending on experience, location, and employer.

What is an instrumentation software engineer?

Instrumentation Software Engineers are professionals who design, develop, and maintain software systems that interface with measurement and control instruments. They write code to collect, process, and analyze data from sensors and equipment, often in fields like manufacturing, scientific research, or industrial automation. Their work ensures that complex instruments operate accurately and reliably, often integrating hardware and software components. They also troubleshoot software issues and optimize systems for performance and reliability.

How does an instrumentation software engineer typically collaborate with hardware and test engineering teams during a project?

Instrumentation Software Engineers work closely with hardware and test engineering teams throughout the project lifecycle. They often participate in cross-functional meetings to understand hardware specifications, define software requirements, and ensure seamless integration between software and physical instruments. Regular communication is essential to troubleshoot issues, validate data acquisition, and optimize system performance. This collaborative approach helps deliver robust, reliable solutions that meet both technical and project goals.

What is the difference between Instrumentation Software Engineer vs Control Systems Engineer?

AspectInstrumentation Software EngineerControl Systems Engineer
Required CredentialsBachelor's in Software, Electrical, or Mechanical Engineering; knowledge of programming languagesBachelor's in Electrical, Mechanical, or Control Engineering; knowledge of control theory and programming
Work EnvironmentDevelops software for instrumentation devices in manufacturing, testing, or automationDesigns and implements control systems in industrial processes or automation
Industry UsageUsed in manufacturing, automation, and testing industriesCommon in industrial automation, process control, and manufacturing sectors

Both roles involve working with automation and control systems, but Instrumentation Software Engineers focus on developing software for instrumentation devices, while Control Systems Engineers design and optimize entire control processes. The roles often overlap but differ in scope and focus.

Are instrumentation software engineers in demand?

Instrumentation software engineers are in demand due to their role in developing and maintaining control systems for manufacturing, aerospace, and energy industries. Skills in programming languages like C++, Python, and experience with real-time operating systems increase employability, and the field often requires knowledge of hardware integration and certifications. Job growth is driven by automation and technological advancements in these sectors.

What are the key skills and qualifications needed to thrive as an instrumentation software engineer?

To thrive as an Instrumentation Software Engineer, you need a strong background in computer science, electronics, and instrumentation engineering, usually with a relevant degree. Familiarity with programming languages (such as Python, C++, or LabVIEW), data acquisition systems, and industry-specific protocols is vital, and certifications in software development or instrumentation can be advantageous. Strong problem-solving abilities, attention to detail, and effective communication skills help you excel in multidisciplinary teams and troubleshoot complex systems. These competencies are crucial for developing reliable software solutions that interface with hardware, ensuring precise measurement and control in technical environments.

What job categories do people searching Instrumentation Software Engineer jobs in California look for?

The top searched job categories for Instrumentation Software Engineer jobs in California are:

Infographic showing various Instrumentation Software Engineer job openings in California as of August 2026, with employment types broken down into 1% Internship, 85% Full Time, 9% Part Time, 2% Temporary, and 3% Contract. Highlights an 87% Physical, 4% Hybrid, and 9% Remote job distribution, with an average salary of $111,898 per year, or $53.8 per hour.

Title Software Development Engineer IV - Windows Instrumentation and Automation

Bruker

Santa Barbara, CA • On-site, Remote

Full-time, Part-time

Medical, Dental, Life, Retirement, PTO

Posted 22 days ago


Bruker rating

7.4

Company rating: 7.4 out of 10

Based on 17 frontline employees who took The Breakroom Quiz


Job description

Software Development Engineer IV - Windows Instrumentation and Automation
Job Locations US-CA-Santa Barbara | US-Remote
Posted Date 3 weeks ago(7/21/2026 4:21 PM)
Req. # 2026-19620
Job Location : Location US-CA-Santa Barbara
Job Location : Postal Code 93117
Job Location : Address 112 Robin Hill Road
Additional Job Locations US-Remote
Type Employee
Full Time/Part Time Full Time
Overview

Bruker is enabling scientists to make breakthrough discoveries and develop new applications that improve the quality of human life. Bruker's high-performance scientific instruments and high-value analytical and diagnostic solutions enable scientists to explore life and materials at molecular, cellular, and microscopic levels. In close cooperation with our customers, Bruker is enabling innovation, improved productivity and customer success in life science molecular research, in applied and pharma applications, in microscopy and nanoanalysis, and in industrial applications, as well as in cell biology, preclinical imaging, clinical phenomics and proteomics research and clinical microbiology.


Today, worldwide more than 11,000 employees are working on this permanent challenge at over 90 locations on all continents. Bruker continues to build upon its extensive range of products and solutions, its broad base of installed systems and a strong reputation among its customers. Being one of the world's leading analytical instrumentation companies, Bruker is strongly committed to further fully meeting its customers' needs as well as continuing to develop state-of-the-art technologies and innovative solutions for today's analytical questions.

The Bruker NANO group is seeking a Staff SW Engineer for Windows Instrumentation and Automation. The Senior Software Engineer will provide programming design and development for Bruker's world leading nano-scale Atomic Force Microscope (AFM) product lines. You will work with other software developers, engineers, and scientists supporting and advancing the state-of-the art nanoscale systems technology by developing software from application design to hardware control. This position requires initiative, innovation, and responsibility working within a cooperative team environment to support existing and realize new customer products.

Location and Work Model

Santa Barbara, California, or fully remote. Remote employees must be able to collaborate effectively with a Santa Barbara-based team with no more than a three-hour time difference. Remote employees may be asked to travel to Santa Barbara up to two times per year.

Position Summary

Join the team building software for the world's most capable automated atomic force microscopes used in leading semiconductor fabs. Our software operates precision hardware, turns complex measurements into reliable results, and gives scientists and engineers intuitive control over sophisticated instruments.

We are seeking a hands-on Staff Software Engineer to own architecture and implementation across Windows desktop applications, real-time and non-real-time instrument workflows, hardware integration, automation, data acquisition, processing, persistence, and interactive visualization. You will provide technical leadership without stepping away from production code.

This is a Windows desktop, scientific instrumentation, and hardware-control position. It is not a web, mobile, or cloud application development role. Candidates whose experience is primarily web application development will not meet the core requirements.

Agentic software development is part of how our team engineers software, not an occasional productivity aid. We use GitHub Copilot Business with leading AI models throughout design, implementation, testing, debugging, refactoring, and review. The successful candidate will bring meaningful production experience with AI coding agents and will be expected to use and advance these workflows responsibly.

Responsibilities

- Architect, design, implement, debug, test, and deploy production software for automated scientific instruments and semiconductor metrology systems.
- Develop responsive, multithreaded Windows applications using C#, .NET, WPF, and modern C++/STL.
- Integrate desktop software with precision motion, nano-positioning, vision, data-acquisition, control, and automation subsystems.
- Design low-latency software that coordinates real-time hardware behavior with non-real-time workflows, data persistence, and intuitive interactive controls.
- Own architecture for new capabilities and guide their integration into a mature product codebase through sound interfaces, layering, refactoring, and incremental delivery.
- Diagnose complex behavior across software and hardware boundaries; lead technical investigations, articulate options and risks, and drive issues to resolution.
- Lead software integration and product deployments in partnership with applications, systems, hardware, test, and manufacturing engineering teams.
- Remain deeply hands-on while providing technical direction and raising engineering quality across a small cross-functional team.
- Use VS Code and AI coding agents as core engineering tools across the software development lifecycle while applying rigorous technical judgment to all generated work.

Qualifications

- 5+ years of professional software engineering experience developing complex production systems.
- 3+ years of hands-on Windows application development using both C#/.NET/WPF and modern C++/STL.
- Strong object-oriented design, API design, debugging, and refactoring skills in a substantial existing codebase.
- Demonstrated experience designing and debugging multithreaded, asynchronous, and performance-sensitive Windows software.
- Experience integrating software with hardware, instruments, robotics, automation equipment, or other physical systems with timing and reliability constraints.
- Experience building interactive desktop user interfaces and the underlying application, data, and device-control layers.
- Demonstrated architecture ownership and technical leadership across subsystem or product boundaries.
- Meaningful, regular use of GitHub Copilot or comparable AI coding agents on production software. Candidates should be prepared to discuss specific examples spanning multiple development activities and how they ensure correctness and maintainability.
- Ability to collaborate clearly with engineers and domain experts, communicate designs and risks, and lead technical work without direct authority.

Education

- MS or PhD in Computer Science, Software Engineering, Electrical Engineering, Mechanical Engineering, Physics, or a related technical field is strongly preferred.
- A BS in a related field combined with significant relevant industry, instrumentation, or research experience will be considered.

Preferred Qualifications

- Experience with C++/CLI, managed/native interoperability, or MFC in a production Windows codebase.
- Experience with scientific instrumentation, semiconductor manufacturing equipment, metrology, robotics, machine vision, motion control, nano-positioning, or automated test equipment.
- Experience using architectural layering across hardware interfaces, control logic, data processing, persistence, and desktop presentation layers.
- Familiarity with signal or image processing, pattern recognition, numerical methods, or analysis of scientific data.
- Domain knowledge of atomic force microscopy, optical spectroscopy, surface metrology, physics, chemistry, or microbiology.
- Experience with Scrum or another Agile development approach and a record of improving practical engineering processes.
- Experience making effective use of both VS Code and Visual Studio in a Windows development environment.

Physical and Environmental Requirements

- When working onsite, ability to lift and move equipment weighing up to 30 pounds, with or without reasonable accommodation.
- Ability and willingness to work periodically in a Class 1000 cleanroom using full gowning protocol and laboratory-appropriate attire. These requirements also apply to remote employees during onsite visits.

At Bruker, base salary is part of our total compensation. The estimated base salary range for this full-time position is between $107,100 and $190,000 and provides an opportunity to progress as you grow and develop within a role. The base salary for the role will depend on a several job-related factors, including, but not limited to education, training, experience, the geographic location of the successful candidate, skills, competencies, job-related knowledge and travel requirements for this position. Full-time employees may also be eligible for a performance-related incentive in addition to a full range of benefits including 401(k) with company match, an employee stock purchase plan, medical and dental plans, life insurance, short-term and long-term disability insurance, employee assistance program and paid time off including vacation, sick time and holidays, and more.

Bruker is an equal-opportunity employer. We evaluate qualified applicants without regard to race, color, religion, sex, sexual orientation, gender identity, national origin, disability, veteran status, and other legally protected characteristics.

Certain positions at Bruker require compliance with export control laws and as a result, all interviewed candidates for all positions will be screened pre-interview to determine their eligibility in light of export control restrictions.


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