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Informatics Engineer Jobs in Chicago, IL (NOW HIRING)

Tempus

Senior Technical Project Manager

Chicago, IL · On-site

$135K - $165K/yr

Work closely with clinical informatics, engineering, and support teams to ensure data quality, compliance, and usability. * Manage customer expectations, ensuring a seamless experience during ...

Tempus

Senior Technical Project Manager

Chicago, IL · On-site

$135K - $165K/yr

Work closely with clinical informatics, engineering, and support teams to ensure data quality, compliance, and usability. * Manage customer expectations, ensuring a seamless experience during ...

Prolaio

Data Architect, Clinical

Chicago, IL · On-site

$65.75 - $84.50/hr

Required : • Bachelor's degree in computer science, Data Engineering, Information Systems, Biomedical Informatics, Engineering, or a related field. • Minimum 10 years of experience in healthcare, ...

Prolaio

Data Architect, Clinical

Chicago, IL · On-site

$65.75 - $84.50/hr

Required : • Bachelor's degree in computer science, Data Engineering, Information Systems, Biomedical Informatics, Engineering, or a related field. • Minimum 10 years of experience in healthcare, ...

Apex Informatics

Devops Engineer

Chicago, IL · On-site

$54.25 - $74.50/hr

... Engineer 4 Location: Chicago, IL /or Dallas ( in office 1 day a week as of now) Duration: 12 months Education & Experience Required: * 8+ years of software development experience * No degree needed

Apex Informatics

Cloud Engineer

Chicago, IL · On-site

$57.50 - $76.75/hr

Requirements: -Bachelor's degree in computer science, Engineering, or related field (or equivalent experience). -5-8 years experience working as a Cloud Engineer or similar role. -Extensive ...

Apex Informatics

Network Engineer

Chicago, IL · On-site

Reporting to the Network Manager, the Senior Network Engineer is seen as a technical expert in Network Engineering infrastructure. This is a technical and hands on role, with a primary focus on ...

Apex Informatics

Citrix Engineer

Chicago, IL · On-site

Contractor's Role: - Support Engineering and Operations of Citrix VDI and W365 virtualization environments - Lead and participate on engineering projects on VDI Team Qualifications (must haves ...

Tempus

Senior Quality Engineer

Chicago, IL · On-site

S. or higher preferred in Computer Science, Software Engineering, Informatics, Biomedical, or relevant engineering disciplines. * 5+ years experience in FDA regulated domain (e.g. medical device ...

Tempus

Senior Quality Engineer

Chicago, IL · On-site +1

S. or higher preferred in Computer Science, Software Engineering, Informatics, Biomedical, or relevant engineering disciplines. * 5+ years experience in FDA regulated domain (e.g. medical device ...

Apex Informatics

Site Reliability Engineer

Chicago, IL · On-site

$58.75 - $78/hr

W (flexible on other 2 days) Site Reliability Engineer - Northern Trust, Goals Driven Wealth Management We are searching for a candidate who has extensive experience in Site Reliability Engineering ...

Prolaio

Data Architect, Clinical

Chicago, IL

$65.75 - $84.50/hr

Bachelor's degree in computer science, Data Engineering, Information Systems, Biomedical Informatics, Engineering, or a related field. * Minimum 10 years of experience in healthcare, life sciences ...

Prolaio

Data Architect, Clinical

Chicago, IL · On-site

$65.75 - $84.50/hr

Bachelor's degree in computer science, Data Engineering, Information Systems, Biomedical Informatics, Engineering, or a related field. * Minimum 10 years of experience in healthcare, life sciences ...

Apex Informatics

Performance Engineer

Chicago, IL · On-site

Working to set up an automation stream that will run the same modules in parallel to the cloud. - Performance Engineers with a lot of Cloud (AWS) project experience - They need to be strong with ...

Apex Informatics

Data engineer

Chicago, IL · On-site

$118K - $141K/yr

Looking for 2 to 4 years of professional experience as a Data engineer Chicago, IL. Skills required: SAAS, SQL, Snowflake and Airflow. * Strong SQL Skills: Proficiency in writing complex queries ...

Apex Informatics

DevOps

Chicago, IL · On-site

$54.25 - $74.50/hr

... Engineer Location: Chicago, IL Required Education • Bachelor's degree in Computer Science, Information Technology, Cybersecurity, Engineering, or a related field (or equivalent work experience ...

Apex Informatics

Data Engineer

Chicago, IL · On-site

$118K - $141K/yr

Demonstrate strong negotiation skills while working with developers, architects to solution the data needs. 3. Validate the accuracy, integrity and quality of Data developed 4. Support defects triage ...

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All JobsInformatics Engineer JobsInformatics Engineer Jobs in Chicago, IL

Informatics Engineer information

See Chicago, IL salary details

$40.2K

$104.9K

$141.8K

How much do informatics engineer jobs pay per year?

As of Jul 14, 2026, the average yearly pay for informatics engineer in Chicago, IL is $104,902.00, according to ZipRecruiter salary data. Most workers in this role earn between $86,600.00 and $120,100.00 per year, depending on experience, location, and employer.

What engineers make $300,000 a year?

Senior-level engineers in specialized fields such as software engineering, data engineering, and systems architecture can earn $300,000 or more annually, especially with extensive experience, advanced skills, and working in high-demand industries like technology or finance. Roles often require advanced certifications, leadership responsibilities, and expertise in tools like cloud platforms or programming languages.

How does an Informatics Engineer typically collaborate with cross-functional teams in a healthcare setting?

Informatics Engineers often work closely with clinicians, IT professionals, and administrative staff to ensure that health information systems meet the needs of all stakeholders. They facilitate communication between technical and non-technical team members, translate clinical requirements into technical specifications, and support the integration of new technologies. This collaborative approach helps ensure that data workflows are efficient, secure, and aligned with healthcare regulations. Regular meetings, user training sessions, and feedback loops are common aspects of this teamwork.

What are Informatics Engineers?

Informatics Engineers are professionals who design, develop, and maintain systems that manage and process information, often in fields like healthcare, business, or research. They combine expertise in computer science, information technology, and domain-specific knowledge to develop solutions that improve data management, analysis, and security. Their work often involves creating software tools, managing databases, and ensuring the efficient flow of information within organizations. Informatics Engineers play a crucial role in integrating technology with real-world processes to enhance decision-making and operational efficiency.

Which is the hardest field in it?

Informatics engineering involves complex fields such as cybersecurity, data science, and software development, each with its own challenges. Cybersecurity is often considered one of the most difficult due to constantly evolving threats and the need for specialized knowledge of networks, cryptography, and threat mitigation. Success in this field requires continuous learning and proficiency with tools like intrusion detection systems and programming languages.

What is the difference between Informatics Engineer vs Data Analyst?

AspectInformatics EngineerData Analyst
Required CredentialsBachelor's or higher in Computer Science, Information Systems, or related fieldsBachelor's in Statistics, Mathematics, or related fields; often with data analysis certifications
Work EnvironmentHealthcare, technology, or research settings focusing on information systemsBusiness, finance, marketing, or healthcare sectors analyzing data trends
Employer & Industry UsageDevelops and manages health or information systems in healthcare and tech industriesInterprets data to inform business decisions across various industries

Informatics Engineers and Data Analysts both work with data, but Informatics Engineers focus on developing and managing information systems, especially in healthcare and tech sectors. Data Analysts primarily interpret data to support business insights. While their skills overlap, their roles differ in scope and application.

What are the key skills and qualifications needed to thrive as an Informatics Engineer, and why are they important?

To thrive as an Informatics Engineer, you need a strong background in computer science, data management, and information systems, usually supported by a relevant degree and experience in software development. Familiarity with programming languages (such as Python or Java), database systems (like SQL), and health informatics standards or certifications (e.g., HL7, Certified Health Informatician) is commonly required. Strong analytical thinking, problem-solving, and effective communication skills help bridge the gap between technical teams and stakeholders. These skills ensure the efficient design, implementation, and maintenance of information systems that support organizational goals and data-driven decision-making.

What is an informatics engineer?

An informatics engineer designs, develops, and manages information systems that integrate computer science and healthcare or other domains. They often work with data analysis, software development, and system implementation, requiring skills in programming, databases, and domain-specific knowledge.

What engineers make $500,000?

Highly experienced engineers in specialized fields such as software engineering, data engineering, or systems engineering can earn $500,000 or more annually, especially in senior or executive roles. These positions often require advanced skills, certifications, and extensive industry experience, typically in high-demand sectors like technology or finance.
What are popular job titles related to Informatics Engineer jobs in Chicago, IL? For Informatics Engineer jobs in Chicago, IL, the most frequently searched job titles are:
What job categories do people searching Informatics Engineer jobs in Chicago, IL look for? The top searched job categories for Informatics Engineer jobs in Chicago, IL are:
Informatics Engineer jobs near you
Infographic showing various Informatics Engineer job openings in Chicago, IL as of July 2026, with employment types broken down into 93% Full Time, 5% Part Time, and 2% Contract. Highlights an 87% Physical, 4% Hybrid, and 9% Remote job distribution, with an average salary of $104,902 per year, or $50.4 per hour.
Senior Technical Project Manager

Senior Technical Project Manager

Tempus

Chicago, IL • On-site

$135K - $165K/yr

Full-time

Re-posted 9 days ago

Job description

Passionate about precision medicine and advancing the healthcare industry?
Recent advancements in underlying technology have finally made it possible for AI to impact clinical care in a meaningful way. Tempus' proprietary platform connects an entire ecosystem of real-world evidence to deliver real-time, actionable insights to physicians, providing critical information about the right treatments for the right patients, at the right time.
We are seeking a highly motivated Senior Technical Project Manager with a strong background in healthcare technology, EHR integrations, and data interoperability. This individual will be responsible for driving the successful execution of clinical data integration projects, collaborating across teams to ensure smooth onboarding, timely delivery, and efficient communication between Tempus and healthcare partners. The ideal candidate will have a deep understanding of EHR workflows, HL7/FHIR integrations, and project management best practices to enable streamlined implementation.
Responsibilities:
  • Lead and manage multiple EHR integration and data ingestion projects, ensuring timelines, deliverables, and stakeholder expectations are met.
  • Serve as the primary liaison between external healthcare organizations, internal engineering teams, and clinical stakeholders, facilitating clear communication and project alignment.
  • Define project scope, timelines, risks, and dependencies while developing detailed implementation plans and workflows.
  • Coordinate with technical teams on HL7 v2, FHIR API, and data transformation requirements to support interoperability.
  • Work closely with clinical informatics, engineering, and support teams to ensure data quality, compliance, and usability.
  • Manage customer expectations, ensuring a seamless experience during implementation, testing, and go-live support.
  • Identify process improvement opportunities to enhance efficiency, scalability, and automation in the integration workflow.
  • Maintain and refine project documentation, best practices, and training materials to support ongoing optimization efforts.

Required Skills and Qualifications:
  • Strong understanding of healthcare interoperability standards (HL7 v2, FHIR, CDA, X12) and data exchange processes.
  • Familiarity with API-based integrations (REST, OAuth 2.0) and data transformation workflows.
  • Ability to manage multiple projects simultaneously, balancing priorities and resource constraints.
  • Strong problem-solving skills and ability to anticipate project risks, dependencies, and mitigation strategies.

Preferred Qualifications:
  • Salesforce reporting
  • Familiarity with formats: JSON, XML
  • Understanding with document repositories: OnBase, Epic Blob
  • Understanding with integration engines: Iguana, Ellkay, CorePoint, Cloverleaf, etc
  • Familiarity with EMRs: Epic, Flatiron, McKesson iKnowMed, Meditech, etc.
  • Understanding of database platforms (On-Prem & Cloud-based): SQL Server, MySQL, AWS Redshift, Google PostgreSQL, Oracle
  • Experience with healthcare terminology concept codes (SNOMED, ICD-10, LOINC, etc.)
  • Knowledge of oncology or genomic data

$135,000-$165,000
The expected salary range above is applicable if the role is performed from Illinois and may vary for other locations (California, Colorado, New York). Actual salary may vary based on qualifications and experience. Tempus offers a full range of benefits, which may include incentive compensation, restricted stock units, medical and other benefits depending on the position.
We are an equal opportunity employer. We do not discriminate on the basis of race, religion, color, national origin, gender, sexual orientation, age, marital status, veteran status, or disability status.

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