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Home Infusion Rn Jobs in Minnesota (NOW HIRING)

Home Infusion Nurse - PRN

Winona, MN

$35.75 - $47.50/hr

We are seeking an infusion nurse (RN) with IVIg experience interested in providing in-home infusions for a local patient. Infusion Details: * Medication: Entyvio - Infuse 300mg IV once every 8 weeks

Home Infusion Nurse - PRN

Saint Paul, MN

$37.50 - $49.50/hr

We are seeking an infusion nurse (RN) with IVIg experience interested in providing in-home infusions for a local patient. Infusion Details: * Medication: Gammagard - Infuse 40 grams IV once every 4 ...

Oncology Infusion RN

Buffalo, MN · On-site

$42.92 - $66.83/hr

MNA-16-Oncology Infusion RN-ROI Weekend Rotation: Alternative Weekend Plan Job Summary: Allina Health is a not-for-profit health system that cares for individuals, families and communities throughout ...

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Home Infusion Rn information

See Minnesota salary details

$19

$43

$72

How much do home infusion rn jobs pay per hour?

As of Jul 28, 2026, the average hourly pay for home infusion rn in Minnesota is $43.57, according to ZipRecruiter salary data. Most workers in this role earn between $32.98 and $50.87 per hour, depending on experience, location, and employer.

What are Home Infusion RNs?

Home Infusion Registered Nurses (RNs) are specialized healthcare professionals who administer medications and treatments, such as intravenous (IV) therapies, to patients in their homes. They assess patient conditions, educate patients and caregivers on medication management, and monitor for side effects or complications. Home Infusion RNs coordinate with physicians and pharmacists to ensure safe and effective treatment, allowing patients to receive necessary therapies outside of a hospital or clinic setting.

What are the key skills and qualifications needed to thrive as a Home Infusion RN, and why are they important?

To thrive as a Home Infusion RN, you need a strong background in IV therapy, medication administration, and nursing assessment, usually supported by an active RN license and infusion therapy certification. Familiarity with infusion pumps, electronic charting systems, and sterile technique is essential for safe and efficient home care. Excellent communication, adaptability, and patient education skills help build trust and ensure effective care in diverse home environments. These skills and qualities are vital for maintaining patient safety, delivering high-quality care, and fostering independence in patients outside of traditional clinical settings.

How to make an extra 2000 a month as a nurse?

Home infusion RNs can increase their income by taking on additional shifts, working overtime, or providing specialized services such as complex medication administration. Obtaining certifications like Certified Infusion Nurse (CIN) can also qualify them for higher-paying roles or freelance opportunities, especially if they have flexible schedules and strong clinical skills.

How to make 150,000 as a nurse?

Home infusion RNs can earn $150,000 or more annually by gaining specialized certifications, such as Certified Registered Nurse Infusion (CRNI), and accumulating extensive experience in outpatient or home infusion settings. Working overtime, taking on leadership roles, or working in high-demand regions can also increase earning potential, especially when combined with strong clinical skills and efficient patient management.

What are some common challenges faced by Home Infusion RNs, and how can they be managed?

Home Infusion RNs often encounter challenges such as managing complex medication regimens, adapting to varied home environments, and working independently without immediate access to a larger medical team. Effective communication with patients, families, and physicians is essential to ensure safety and adherence to protocols. Building strong organizational skills and maintaining up-to-date knowledge of infusion therapy best practices can help RNs confidently address these challenges while providing high-quality patient care.

What is the difference between Home Infusion Rn vs Home Health Nurse?

AspectHome Infusion RnHome Health Nurse
CertificationsRN license, infusion therapy certificationRN license, sometimes additional certifications in home health
Work EnvironmentAdministers IV medications, infusions at patients' homesProvides broad nursing care, including wound care and vital signs at home
Employer & IndustryHome infusion companies, specialty pharmaciesHome health agencies, hospice providers

Home Infusion Rns specialize in administering IV therapies and infusions, focusing on medication delivery at home. Home Health Nurses provide comprehensive nursing care, including wound management and vital sign monitoring. While both roles work in patients' homes and require RN licensure, Home Infusion Rns have additional infusion therapy certifications and focus on medication administration, whereas Home Health Nurses offer broader nursing services.

Is there a demand for infusion nurses?

Home infusion RNs are in high demand due to the increasing need for outpatient and home-based healthcare services. They require specialized skills in IV therapy, patient education, and often hold certifications such as the Infusion Nursing Certification (CRNI). The growth of chronic disease management and outpatient treatments contributes to a strong job market for infusion nurses.

How to make $300,000 as a nurse online?

Home infusion RNs can increase earnings by gaining specialized certifications, such as in infusion therapy or pharmacology, and by working overtime or on a per diem basis. Building a strong reputation and leveraging telehealth platforms or consulting opportunities can also help increase income, but reaching $300,000 annually typically requires multiple income streams or advanced roles within the field.
What cities in Minnesota are hiring for Home Infusion Rn jobs? Cities in Minnesota with the most Home Infusion Rn job openings:
Infographic showing various Home Infusion Rn job openings in Minnesota as of July 2026, with employment types broken down into 2% As Needed, 52% Full Time, 38% Part Time, 2% Temporary, and 6% Contract. Highlights an 100% In-person job distribution, with an average salary of $90,620 per year, or $43.6 per hour.
Home Infusion Nurse - PRN

Home Infusion Nurse - PRN

National Recruiters

Winona, MN

$35.75 - $47.50/hr

Per diem

Posted 18 hours ago


Job description

We are seeking an infusion nurse (RN) with IVIg experience interested in providing in-home infusions for a local patient.

Infusion Details:

  • Medication: Entyvio - Infuse 300mg IV once every 8 weeks
  • Length of treatment:  1 Hour + Prep Time
  • Location: Winona, MN 55987
  • Date of Service: Patient is due 9/19
  • Access: PIV
  • Pump: No pump; administered via gravity
Preferences:
  • The patient is flexible with the start time
  • The patient has a dog in the home
Responsibilities of the PRN Home Infusion Registered Nurse
  • Deliver immune globulin infusion therapies directly to the patient in the comfort of their home.
  • Make a meaningful impact by leveraging your clinical IV expertise and compassionate care to support patients within their environment.
  • Provide personalized, one-on-one home infusion nursing care visits and patient education aligned with the physician's treatment plan.
  • Demonstrate outstanding written and verbal communication skills to effectively engage with patients, physicians, pharmacists, and other collaborative partners.

Requirements of the PRN Home Infusion Registered Nurse:

  • Active and unencumbered nursing license in the state of practice
  • Current BLS certification for Healthcare Providers (approved by the American Heart Association or American Red Cross)
  • IVIg experience required
  • In-home infusion experience is generally required. Exceptions may apply.
  • A valid driver's license and proof of liability insurance are required, with access to a vehicle for business-related travel
  • A clear background check
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