1

High Performance Computing Hpc Jobs in Indiana (NOW HIRING)

You will work with HPC engineers and scientific computing specialists to develop robust, scalable, high-performance cloud native infrastructure that underpins modernization of the scientific ...

Be a catalyst for innovation in high performance computing at Lilly-seize the chance to transform and accelerate our HPC future! The Cloud and Connectivity organization is seeking an HPC Platform ...

You will also have an opportunity to partner with the AI/ML and High-Performance Computing (HPC) teams. Additionally, you would be one of the senior Linux platform engineer directing the global Linux ...

Altair is a global technology company providing software and cloud solutions in the areas of data analytics, product development, and high-performance computing (HPC). Altair enables organizations in ...

Altair is a global technology company providing software and cloud solutions in the areas of product development, high-performance computing (HPC) and artificial intelligence (AI). Altair enables ...

Altair is a global technology company providing software and cloud solutions in the areas of data analytics, product development, and high-performance computing (HPC). Altair enables organizations in ...

We set the benchmark for excellence with our top-tier solutions in high-performance computing deployments, supporting the advancement of AI computing with precision, speed, and minimal downtime. Our ...

next page

Showing results 1-20

High Performance Computing Hpc information

See Indiana salary details

$30.9K

$64.9K

$106.6K

How much do high performance computing hpc jobs pay per year?

As of Jun 20, 2026, the average yearly pay for high performance computing hpc in Indiana is $64,943.00, according to ZipRecruiter salary data. Most workers in this role earn between $48,500.00 and $79,000.00 per year, depending on experience, location, and employer.

What is the difference between High Performance Computing Hpc vs Data Scientist?

AspectHigh Performance Computing (HPC)Data Scientist
Required credentialsDegree in Computer Science, Engineering, or related fields; often certifications in parallel computing or HPC systemsDegree in Data Science, Statistics, Computer Science, or related fields; certifications in data analysis or machine learning
Work environmentSupercomputing centers, research labs, large enterprises with high computational needsTech companies, finance, healthcare, research institutions, often in office or remote settings
Industry usageScientific research, simulations, modeling, large-scale data processingData analysis, predictive modeling, machine learning, business insights

While both roles involve working with large datasets and complex computations, HPC specialists focus on designing and maintaining high-performance computing systems for scientific and engineering tasks. Data scientists analyze data to extract insights and build models. The roles often overlap in data processing but differ in technical focus and environment.

What are some common challenges faced by professionals working in High Performance Computing (HPC) environments?

Professionals in HPC roles often encounter challenges such as optimizing code for parallel processing, managing complex and rapidly evolving hardware architectures, and troubleshooting large-scale distributed systems. Collaborating closely with researchers and domain experts is also essential to ensure that computational resources are used efficiently and effectively. Keeping up with advances in both hardware and software, as well as balancing multiple projects with tight deadlines, are typical aspects of the HPC work environment.

What is High Performance Computing (HPC)?

High Performance Computing (HPC) refers to the use of supercomputers and parallel processing techniques to solve complex computational problems quickly and efficiently. HPC systems combine the power of multiple processors to perform billions or even trillions of calculations per second, making them essential for scientific research, engineering simulations, data analytics, and other demanding tasks. These systems are used in fields such as weather forecasting, molecular modeling, financial modeling, and artificial intelligence. By leveraging HPC, organizations can tackle problems that are too large or complex for standard computers.

What are the key skills and qualifications needed to thrive as a High Performance Computing (HPC) specialist, and why are they important?

To thrive as a High Performance Computing (HPC) specialist, you need a solid background in computer science or engineering, strong programming skills (especially in languages like C, C++, or Python), and expertise in parallel computing and Linux systems. Familiarity with cluster management tools, job schedulers (e.g., SLURM or PBS), and experience with HPC libraries and accelerators such as MPI, OpenMP, and GPU programming are typically required. Excellent problem-solving abilities, teamwork, and effective communication skills help you collaborate with researchers and resolve complex technical challenges. These competencies are vital for optimizing computational workflows, maintaining robust systems, and enabling advanced scientific or industrial research.
What are popular job titles related to High Performance Computing Hpc jobs in Indiana? For High Performance Computing Hpc jobs in Indiana, the most frequently searched job titles are:
What job categories do people searching High Performance Computing Hpc jobs in Indiana look for? The top searched job categories for High Performance Computing Hpc jobs in Indiana are:
Infographic showing various High Performance Computing Hpc job openings in Indiana as of June 2026, with employment types broken down into 4% Internship, 16% As Needed, 45% Full Time, 7% Part Time, 24% Temporary, and 4% Contract. Highlights an 93% Physical, 2% Hybrid, and 5% Remote job distribution, with an average salary of $64,943 per year, or $31.2 per hour.
Staff Engineer High Performance Computing

Staff Engineer High Performance Computing

Pfizer

On-site

Full-time

Medical, Dental, Vision, Retirement, PTO

Posted 11 days ago


Pfizer rating

8.3

Company rating: 8.3 out of 10

Based on 122 frontline employees who took The Breakroom Quiz

24th of 71 rated pharmaceutical


Job description

ROLE SUMMARY

Pfizer is committed to the application of computational science in the areas of drug discovery and development and has recently initiated a large-scale migration of computational infrastructure to cloud. This role provides technical vision and will drive the execution of high-performance computing (HPC) solutions that support computational workloads across the organization.

We are seeking an experienced individual to lead the technical architecture of the cloud HPC platform. Key responsibilities include establishing go-forward cloud HPC platform computing technologies, implementing robust engineering practices, championing infrastructure as code (IaC), and configuring core services that support HPC at scale in the cloud environment. You will work with HPC engineers and scientific computing specialists to develop robust, scalable, high-performance cloud native infrastructure that underpins modernization of the scientific computing platform.

ROLE RESPONSIBILITIES

Strategic Leadership

This role will lead development and operationalize cloud-based HPC infrastructure required for research, modeling, and large-scale data processing across multiple cloud environments.

  • Serve as a primary technical expert; evaluate, advocate for, and drive consensus among senior managers and engineers for the go-forward technology platforms and toolkits used for HPC service delivery.
  • Collaborate with stakeholders, users, and leaders to develop a long-term technical roadmap for cloud-based HPC services.
  • Lead deep-dive discussions with technical partners at major cloud providers, defining HPC-related requirements and deliverables for Statements of Work.
  • Drive a culture of shared ownership, transparency, and engineering excellence through mentoring, coaching, and example setting.
  • Perform troubleshooting, system analysis, and benchmarking to manage escalated, difficult to resolve issues and maintain a high-performance environment.


HPC Platform Architecture and Engineering

  • Design and own robust and dependable high-throughput, parallel, low-latency infrastructure for HPC and ML/AI workloads in multiple cloud environments (AWS/GCP).
  • Establish technical standards, best practices, architectural frameworks, and implementation guidelines for reproducible HPC platform and application deployments.
  • Recommend cutting-edge HPC technologies including specialized accelerators, novel storage solutions, managed services, and open-source toolkits that will be integrated into the platform.
  • Own OS image development, job scheduler configuration, high performance storage systems
  • Ensure high performance, reliability, scalability, cost efficiency, and security.

Automation and DevOps

  • Drive adoption of infrastructure automation using IaC tools like Terraform and CloudFormation.
  • Establish, promote, and enforce internal standards (naming, tagging, documentation, version control, and change procedures) to ensure repeatable environment provisioning and scaling.
  • Establish infrastructure lifecycle management procedures, from provisioning to operations, support, updating, and teardown of production computing platforms.

Monitoring and Reliability

  • Determine KPIs to guide monitoring, logging, and alerting strategies for the infrastructure.
  • Collaborate with stakeholders, users, and senior managers to develop meaningful user-facing dashboards, drive resource management, cost efficiency, and workload optimization.
  • Design workflows, alerting systems and utilities to improve observability, user, or administrator experiences.

BASIC QUALIFICATIONS

  • B.S. in computer science, life science, data science or similar fields with 6+ years of experience in cloud infrastructure engineering.
  • A proven track record of developing and supporting robust HPC frameworks in a cloud environment.
  • Expert level experience with at least one of AWS and GCP, including knowledge of core compute and storage services relevant to HPC.
  • Deep understanding of modern CI/CD practices, observability and monitoring of cloud-based HPC infrastructure.
  • Strong knowledge of distributed systems and production system reliability.
  • Familiarity with monitoring and observability frameworks (CloudWatch, Prometheus, Grafana, etc.)
  • Solid understanding of cloud networking, identity, security controls, and core services.

PREFERRED QUALIFICATIONS

  • M.S. in computer science, life science, data science or similar fields.
  • 10-15 years experience in HPC/Cloud engineering
  • Expertise with distributed computing environments, especially EKS/GKE/Kubernetes
  • Deep experience with HPC environments, job schedulers, and NVIDIA GPU compute.
  • Prior experience with HPC deployment utilities including AWS ParallelCluster and Parallel Computing Services, and Google Cloud Cluster Toolkit
  • Familiarity with other aspects of managing HPC services in a cloud environment: cloud financial models, cost optimization, user support services, application delivery, Linux administration, job scheduling, resource optimization.

Candidate demonstrates a breadth of diverse leadership experiences and capabilities including: the ability to influence and collaborate with peers, develop and coach others, oversee and guide the work of other colleagues to achieve meaningful outcomes and create business impact.

NON-STANDARD WORK SCHEDULE, TRAVEL OR ENVIRONMENT REQUIREMENTS

Occasional travel may be required


Work Location Assignment:Hybrid

The annual base salary for this position ranges from $124,400.00 to $207,400.00. In addition, this position is eligible for participation in Pfizer's Global Performance Plan with a bonus target of 17.5% of the base salary and eligibility to participate in our share based long term incentive program. We offer comprehensive and generous benefits and programs to help our colleagues lead healthy lives and to support each of life's moments. Benefits offered include a 401(k) plan with Pfizer Matching Contributions and an additional Pfizer Retirement Savings Contribution, paid vacation, holiday and personal days, paid caregiver/parental and medical leave, and health benefits to include medical, prescription drug, dental and vision coverage. Learn more at Pfizer Candidate Site - U.S. Benefits | (uscandidates.mypfizerbenefits.com). Pfizer compensation structures and benefit packages are aligned based on the location of hire. The United States salary range provided does not apply to Tampa, FL or any location outside of the United States. This role is posted in multiple locations. If you are applying for the role in an secondary job posting location where pay transparency regulations apply, your Talent Advisor will share the local pay information with you during the first interview.

Relocation assistance may be available based on business needs and/or eligibility.

Candidates must be authorized to be employed in the U.S. by any employer.

U.S. work visa sponsorship (such as TN, O-1, H-1B, etc.) is not available for this role now or in the future.

Sunshine Act

Pfizer reports payments and other transfers of value to health care providers as required by federal and state transparency laws and implementing regulations. These laws and regulations require Pfizer to provide government agencies with information such as a health care provider's name, address and the type of payments or other value received, generally for public disclosure. Subject to further legal review and statutory or regulatory clarification, which Pfizer intends to pursue, reimbursement of recruiting expenses for licensed physicians may constitute a reportable transfer of value under the federal transparency law commonly known as the Sunshine Act. Therefore, if you are a licensed physician who incurs recruiting expenses as a result of interviewing with Pfizer that we pay or reimburse, your name, address and the amount of payments made currently will be reported to the government. If you have questions regarding this matter, please do not hesitate to contact your Talent Acquisition representative.

EEO & Employment Eligibility

Pfizer is committed to equal opportunity in the terms and conditions of employment for all employees and job applicants without regard to race, color, religion, sex, sexual orientation, age, gender identity or gender expression, national origin, disability or veteran status. Pfizer also complies with all applicable national, state and local laws governing nondiscrimination in employment as well as work authorization and employment eligibility verification requirements of the Immigration and Nationality Act and IRCA. Pfizer is an E-Verify employer. This position requires permanent work authorization in the United States.

Pfizer endeavors to makewww.pfizer.com/careersaccessible to all users. If you would like to contact us regarding the accessibility of our website or need assistance completing the application process and/or interviewing, please emaildisabilityrecruitment@pfizer.com. This is to be used solely for accommodation requests with respect to the accessibility of our website, online application process and/or interviewing. Requests for any other reason will not be returned.

To learn more about acceptable and prohibited uses of AI during the recruitment process, please review our candidate AI-use guidelines available onPfizer Careers.

Information & Business Tech

What Pfizer employees say

Pay

Benefits

Hours and flexibility

Workplace

Get the full story on Breakroom


Pfizer logo

About Pfizer

Sourced by ZipRecruiter

All over the world, Pfizer colleagues work together to positively impact health for everyone, everywhere. Our colleagues have the opportunity to grow and develop a career that offers both individual and company success; be part of an ownership culture that values diversity and where all colleagues are energized and engaged; and the ability to impact the health and lives of millions of people. Pfizer, a global leader in the biopharmaceutical industry, is continuously seeking top talent who are inspired by our purpose to innovate to bring therapies to patients that significantly improve their lives. Our Health and Science System Specialists Team provides leadership across patient care settings in the complex Hospital, Health System, and Key Medical Group environment to bring value to our customers and patients in this dynamic ecosystem.

Industry

Pharmaceutical and medicine manufacturing

Company size

10,000+ Employees

Headquarters location

New York, NY, US

Year founded

1849