Position Summary
We are partnering with an innovative gene therapy organization in the RTP area seeking a Senior Scientist to support bioanalytical and molecular biology research activities. This individual will play a key role in executing and optimizing a variety of molecular and cellular assays focused on DNA, RNA, proteins, and cell-based systems. The ideal candidate brings strong technical expertise, experience in fast-paced biotech environments, and a collaborative, solution-oriented mindset.
Key Responsibilities
- Execute molecular biology experiments involving nucleic acids, proteins, and mammalian or bacterial cell systems.
- Perform and troubleshoot techniques including PCR, qPCR, ddPCR, cloning, sequencing, plasmid preparation, CE, ELISA, SDS-PAGE, and Western blotting.
- Design, clone, evaluate, and optimize AAV GOI plasmid constructs.
- Develop, refine, and document laboratory assays, workflows, and experimental procedures.
- Maintain laboratory inventory, reagents, and instrumentation to support efficient lab operations.
- Review current scientific literature and incorporate emerging molecular biology methodologies as appropriate.
- Support additional laboratory and research activities as needed.
Qualifications
- Bachelor’s, Master’s, or PhD degree in Life Sciences or a related scientific discipline.
- Minimum of 2 years of relevant hands-on molecular biology experience in a laboratory setting.
- Strong expertise in recombinant DNA cloning, plasmid isolation, and molecular analysis techniques.
- Experience with large-scale plasmid DNA preparation and ITR-containing plasmids.
- Proficiency with analytical and molecular techniques including PCR, qPCR, ddPCR, CE, ELISA, SDS-PAGE, and Western blotting.
- Experience developing SOPs, laboratory protocols, and analytical procedures.
- Working knowledge of GLP, GCLP, or related quality standards.
- Strong communication, organizational, and collaboration skills.
- Demonstrated ability to work independently while contributing effectively within a team environment.
- Proficiency with Microsoft Office Suite, SoftMax, JMP, and GraphPad Prism.
****Thank you for your interest in this opportunity! Due to the high volume of applications we receive, we are unable to respond to every applicant individually. If you do not hear from us regarding this role, it means we have moved forward with other candidates at this time. We sincerely appreciate your interest and encourage you to apply for future opportunities that match your experience and career goals.