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Spatial Biology Jobs in Raleigh, NC (NOW HIRING)

Duke University

Bioinformatician II

Durham, NC · On-site

$94K - $150K/yr

The successful candidate will play a central role in analyzing and integrating single-cell, spatial transcriptomic, and multi-omic datasets to uncover new biological insights and therapeutic ...

Duke University

Bioinformatician II

Durham, NC · On-site

$94K - $150K/yr

The successful candidate will play a central role in analyzing and integrating single-cell, spatial transcriptomic, and multi-omic datasets to uncover new biological insights and therapeutic ...

Duke University

POSTDOCTORAL ASSOCIATE

Durham, NC

A postdoctoral Research Associate (computational biology and bioinformatics area) position is open ... spatial genomics, digital pathology data, and apply the computational methods to understand ...

Duke University

POSTDOCTORAL ASSOCIATE

Durham, NC · On-site

A postdoctoral Research Associate (computational biology and bioinformatics area) position is open ... spatial genomics, digital pathology data, and apply the computational methods to understand ...

Duke University

POSTDOCTORAL ASSOCIATE

Durham, NC · On-site

D. in computational biology, bioinformatics, computer science, statistics, genetic epidemiology, or a related field. Expertise in analysis of single cell or spatial sequencing data is required.

Duke University

POSTDOCTORAL ASSOCIATE

Durham, NC · On-site

D. in computational biology, bioinformatics, computer science, statistics, genetic epidemiology, or a related field. Expertise in analysis of single cell or spatial sequencing data is required.

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All JobsSpatial Biology JobsSpatial Biology Jobs in Raleigh, NC

Spatial Biology information

See Raleigh, NC salary details

$22.4K

$50.7K

$72.4K

How much do spatial biology jobs pay per year?

As of Jun 15, 2026, the average yearly pay for spatial biology in Raleigh, NC is $50,733.00, according to ZipRecruiter salary data. Most workers in this role earn between $42,800.00 and $58,800.00 per year, depending on experience, location, and employer.

What is spatial biology?

Spatial biology is a field of science that studies the spatial organization and interactions of cells and molecules within tissues. By analyzing where specific cells and proteins are located in relation to each other, researchers can gain insights into how tissues function in health and disease. Techniques such as spatial transcriptomics and multiplex imaging are commonly used in spatial biology to map and visualize these complex relationships. This information is valuable for understanding diseases like cancer, where the tissue environment plays a critical role.

What are some common challenges faced by professionals working in spatial biology, and how can they be addressed?

Professionals in spatial biology often encounter challenges related to managing and interpreting large, complex datasets generated from advanced imaging and sequencing technologies. Integrating multidisciplinary knowledge—such as molecular biology, bioinformatics, and imaging analysis—is also essential, requiring ongoing learning and collaboration across fields. These challenges can be addressed by staying current with technological advancements, utilizing robust data analysis tools, and actively collaborating with bioinformaticians, pathologists, and other specialists to ensure accurate data interpretation and project success.

What are the key skills and qualifications needed to thrive as a Spatial Biologist, and why are they important?

To thrive as a Spatial Biologist, you need a strong background in molecular biology, histology, and data analysis, typically supported by an advanced degree in biology or related fields. Familiarity with spatial transcriptomics platforms, imaging technologies, and bioinformatics tools such as R or Python is essential. Strong problem-solving abilities, attention to detail, and effective teamwork are vital soft skills for excelling in this role. These skills ensure accurate experimental design, data interpretation, and collaborative progress in cutting-edge biological research.

What is the difference between Spatial Biology vs Cell Biologist?

AspectSpatial BiologyCell Biologist
Required CredentialsMaster's or PhD in Biology, Biotechnology, or related fieldsMaster's or PhD in Cell Biology, Molecular Biology, or related fields
Work EnvironmentResearch labs, biotech companies, academic institutions focusing on tissue and cellular spatial analysisLaboratories, research institutions studying cell structure, function, and mechanisms
Industry UsageUsed in genomics, proteomics, and tissue analysis to understand spatial contextApplied in basic and applied research on cell function and disease mechanisms

Spatial Biology and Cell Biologist roles share foundational biology knowledge and advanced laboratory skills. However, Spatial Biology focuses on analyzing the spatial organization of molecules within tissues, often requiring specialized imaging techniques, while Cell Biologists study cell structure and function more broadly. Both roles are vital in research and biotech industries, but Spatial Biology is more specialized in spatial analysis techniques.

What are popular job titles related to Spatial Biology jobs in Raleigh, NC? For Spatial Biology jobs in Raleigh, NC, the most frequently searched job titles are:
What job categories do people searching Spatial Biology jobs in Raleigh, NC look for? The top searched job categories for Spatial Biology jobs in Raleigh, NC are:
What cities near Raleigh, NC are hiring for Spatial Biology jobs? Cities near Raleigh, NC with the most Spatial Biology job openings:
Spatial Biology jobs near you
Bioinformatician II

Bioinformatician II

Duke University

Durham, NC • On-site

$94K - $150K/yr

Other

Medical, Dental, Retirement

Posted 11 days ago

Duke University rating

6.5

Company rating: 6.5 out of 10

Based on 54 frontline employees who took The Breakroom Quiz

438th of 537 rated colleges and universities

Job description

School of Medicine Established in 1930, Duke University School of Medicine is the youngest of the nation's top medical schools. Ranked sixth among medical schools in the nation, the School takes pride in being an inclusive community of outstanding learners, investigators, clinicians, and staff where interdisciplinary collaboration is embraced and great ideas accelerate translation of fundamental scientific discoveries to improve human health locally and around the globe. Composed of more than 2,600 faculty physicians and researchers, nearly 2,000 students, and more than 6,200 staff, the Duke University School of Medicine along with the Duke University School of Nursing, and Duke University Health System comprise Duke Health, a world-class academic medical center. The Health System encompasses Duke University Hospital, Duke Regional Hospital, Duke Raleigh Hospital, Duke Health Integrated Practice, Duke Primary Care, Duke Home Care and Hospice, Duke Health and Wellness, and multiple affiliations.

Be You.

Bioinformatician II - Cancer Genomics & Single-Cell Biology

The Oliver Lab at Duke University (www.theoliverlab.com) is seeking a highly motivated Bioinformatician II to join a multidisciplinary research team focused on understanding the mechanisms that drive tumor lineage plasticity, heterogeneity, and drug resistance in lung cancer. Building on recent discoveries (Finlay et al, Cancer Cell, 2024 and Ireland et al., Nature, 2025), our work integrates advanced computational and experimental approaches to define how tumors evolve under therapeutic pressure.

This position offers the opportunity to work at the interface of cancer biology, genomics, and data science, leveraging large-scale datasets from genetically engineered mouse models, organoid systems, and human tumor specimens. The successful candidate will play a central role in analyzing and integrating single-cell, spatial transcriptomic, and multi-omic datasets to uncover new biological insights and therapeutic vulnerabilities.

Minimum Requirements: 

  • PhD in Bioinformatics, Computational Biology, Genomics, Computer Science, or a related field (or MS with substantial relevant experience) 
  • Strong programming skills (e.g., Python, R, or equivalent) 
  • Experience analyzing high-dimensional genomic data, particularly RNA-seq or single-cell datasets 
  • Demonstrated ability to work independently and flexibly manage multiple projects 
  • Strong communication skills and ability to collaborate in a team-oriented environment 

Preferred Qualifications: 

  • Experience with single-cell and/or spatial transcriptomics analysis 
  • Familiarity with multi-omics data integration 
  • Experience applying machine learning or statistical modeling to biological datasets 
  • Experience working in cancer biology or related biomedical fields 
  • Experience with high-performance computing environments and reproducible workflows 

Be Bold.                                         

  • Lead and contribute to the analysis of single-cell RNA-seq, spatial transcriptomics, and multi-omic datasets from mouse and human cancer models 
  • Develop and implement computational pipelines for large-scale genomic data analysis and integration 
  • Apply statistical and machine learning approaches to identify cell states, lineage relationships, and mechanisms of therapy resistance 
  • Collaborate closely with experimental biologists to design analyses, interpret results, and guide hypothesis generation 
  • Contribute to manuscript preparation, grant applications, and presentation of findings at scientific meetings 
  • Mentor trainees and contribute to a collaborative and interdisciplinary research environment 

 

Choose Duke.                                                                                                                                                                                                                                                          

  • Work on cutting-edge questions in cancer biology with direct relevance to therapy resistance and precision medicine 
  • Access to rich, multi-modal datasets from state-of-the-art experimental systems and human tumors 
  • Collaborative, interdisciplinary environment integrating computational and experimental approaches 
  • Strong track record of high-impact publications and career development for trainees

Anticipated Pay Range: Duke University provides an annual base salary range for this position as USD $94,156.00 to USD $150,733.00. Duke University considers factors such as (but not limited to) scope and responsibilities of the position; candidate's work experience, education/training, and key skills; internal peer equity; as well as market and organizational considerations when extending an offer.


Your total compensation goesbeyond the dollars on your paycheck. Duke provides comprehensive and competitive medical and dental care programs, generous retirement benefits, and a wide array of family-friendly and cultural programs to eligible team members. Learn more at: https://hr.duke.edu/benefits/


Equal Opportunity Employer: Duke is an Equal Opportunity Employer committed to providing employment opportunity without regard to an individual's age, color, disability, gender,gender expression, gender identity, genetic information, national origin, race, religion, sex (including pregnancy and pregnancy- related conditions), sexual orientation, or military status.


Duke aspires to create a community built oncollaboration, innovation, creativity, and belonging. Our collective success depends on the robust exchange of ideas-an exchange that is best when the rich diversity of our perspectives, backgrounds, and experiences flourishes. To achieve this exchange, it is essential that all members of the community feel secure and welcome, that the contributions of all individuals are respected, and that all voices are heard. All members of our community have a responsibility to uphold these values.


Essential Physical Job Functions:
Certain jobs at Duke University and Duke University Health System may include essential job functions that require specific physical and/or mental abilities. Additional information and reasonable accommodation(s) can be requested with Duke Access and Accommodations Services (email: DAAS@duke.edu; phone: 919-668-1267).

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About Duke University

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Duke is regarded as one of America's leading research universities. Located in Durham, North Carolina, Duke is positioned in the heart of the Research Triangle, which is ranked annually as one of the best places in the country to work and live. Duke has more than 15,000 students who study and conduct research in its 10 undergraduate, graduate, and professional schools. With about 40,000 employees, Duke is the third largest private employer in North Carolina, and it now has international programs in more than 150 countries.

Industry

Colleges, universities, and professional schools and hospitals

Company size

10,000+ Employees

Headquarters location

Durham, NC, US

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