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Full Time Downstream Process Development Scientist Jobs in Tennessee

The Pictsweet Company

Food Scientist

Bells, TN

... the development and commercialization of innovative and high-quality food products. The Food ... Solve technical problems in product formulation, processing and packaging * Conduct sensory ...

FC Renew

Senior Scientist

Knoxville, TN · On-site

$87K - $119K/yr

Our core technology is a life-extension renewal process for proton exchange membrane hydrogen fuel ... Our research and development is currently supported and funded by the U.S. Army, U.S. Department of ...

Asurion

Senior Research & Development Engineer

Nashville, TN

$100K - $138K/yr

... process innovation, and R&D initiatives across Asurion's operations. Reporting to an Engineering ... This is a full-time, on-site, exempt position. Duties & Responsibilities: * Design and optimize ...

Marsh McLennan

Senior Enterprise Architect

Knoxville, TN · On-site

... downstream process dependencies across core servicing, transaction, and operational workflows ... Manage the development of supporting application components, interface/design of systems as well as ...

FC Renew

Senior Scientist

Knoxville, TN · Hybrid

$87K - $119K/yr

Our research and development is currently supported and funded by the U.S. Army, U.S. Department of ... Employment Type: FULL_TIME

Marsh McLennan

Senior Enterprise Architect

Kingsport, TN · On-site

... downstream process dependencies across core servicing, transaction, and operational workflows ... Manage the development of supporting application components, interface/design of systems as well as ...

Marsh McLennan

Senior Enterprise Architect

Memphis, TN · On-site

... downstream process dependencies across core servicing, transaction, and operational workflows ... Manage the development of supporting application components, interface/design of systems as well as ...

Marsh McLennan

Senior Enterprise Architect

Nashville, TN · On-site

... downstream process dependencies across core servicing, transaction, and operational workflows ... Manage the development of supporting application components, interface/design of systems as well as ...

The Pictsweet Company

Food Scientist

Bells, TN

... the development and commercialization of innovative and high-quality food products. The Food ... Solve technical problems in product formulation, processing and packaging * Conduct sensory ...

The Pictsweet Company

Food Scientist

Bells, TN · On-site

... the development and commercialization of innovative and high-quality food products. The Food ... Solve technical problems in product formulation, processing and packaging * Conduct sensory ...

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All JobsDownstream Process Development Scientist JobsFull Time Downstream Process Development Scientist JobsFull Time Downstream Process Development Scientist Jobs in Tennessee

Full Time Downstream Process Development Scientist information

What does a full time downstream process development scientist do?

A Full Time Downstream Process Development Scientist is responsible for designing, optimizing, and scaling up processes that purify biological products such as proteins, antibodies, or vaccines after they are produced in cells or microbes. This role involves developing and improving techniques like filtration, chromatography, and centrifugation to ensure high purity and yield of the final product. The scientist also conducts experiments, analyzes data, and collaborates with cross-functional teams to transfer processes from the lab to manufacturing. Their work is critical for producing safe and effective biopharmaceuticals on a large scale.

What are the key skills and qualifications needed to thrive as a full time downstream process development scientist, and why are they important?

To thrive as a Full Time Downstream Process Development Scientist, you need a strong background in biochemical engineering, protein purification, and analytical techniques, typically supported by a degree in biochemistry, biotechnology, or a related field. Proficiency with chromatography systems (e.g., HPLC, FPLC), filtration technologies, and knowledge of regulatory and quality systems like GMP is essential. Strong problem-solving abilities, teamwork, and effective communication skills help you collaborate with cross-functional teams and troubleshoot process challenges. These skills are crucial for developing robust purification processes that ensure product quality, regulatory compliance, and efficient production in biopharmaceutical environments.

What are some typical challenges faced by a full time downstream process development scientist, and how can they be addressed?

Downstream Process Development Scientists often encounter challenges such as optimizing protein purification processes to achieve high yield and purity, troubleshooting unexpected impurities, and scaling up processes from laboratory to manufacturing scale. These tasks require strong problem-solving skills, meticulous attention to detail, and effective collaboration with upstream teams, analytical scientists, and manufacturing staff. Addressing these challenges involves staying current with new purification technologies, maintaining robust documentation, and participating in cross-functional meetings to ensure seamless process integration and regulatory compliance.

What is the difference between Full Time Downstream Process Development Scientist vs Downstream Process Engineer?

AspectFull Time Downstream Process Development Scientist
Primary FocusDesigning, optimizing, and developing downstream purification processes for biopharmaceuticals
Required CredentialsBachelor's or Master's in Biotechnology, Biochemistry, or related field; experience in process development
Work EnvironmentLaboratories, R&D settings, collaborative teams in biotech or pharma companies
Typical ResponsibilitiesProcess scale-up, method validation, troubleshooting, documentation

While both roles involve downstream bioprocessing, the Full Time Downstream Process Development Scientist focuses on process development and optimization, whereas the Downstream Process Engineer typically handles process implementation and manufacturing support. The scientist role emphasizes research and development, while the engineer role is more operational. Candidates often hold similar degrees and certifications, but their daily tasks and focus areas differ.

How much does a full time downstream process development scientist make?

In California, a full-time downstream process development scientist typically earns between $80,000 and $130,000 annually, depending on experience, education, and the specific employer. Salaries may also include benefits such as health insurance and bonuses, with higher compensation often associated with advanced skills in bioprocessing and laboratory techniques.

What is a full time downstream process development scientist?

A full-time downstream process development scientist specializes in designing, optimizing, and scaling the purification processes used in biopharmaceutical manufacturing, such as chromatography and filtration. They work to improve product yield, purity, and efficiency, often using laboratory techniques and process modeling tools, typically within a regulated environment requiring compliance with industry standards.

What are the most commonly searched types of Downstream Process Development Scientist jobs in Tennessee?

The most popular types of Downstream Process Development Scientist jobs in Tennessee are:

What are popular job titles related to Full Time Downstream Process Development Scientist jobs in Tennessee?

For Full Time Downstream Process Development Scientist jobs in Tennessee, the most frequently searched job titles are:

What job categories do people searching Full Time Downstream Process Development Scientist jobs in Tennessee look for?

The top searched job categories for Full Time Downstream Process Development Scientist jobs in Tennessee are:

What cities in Tennessee are hiring for Full Time Downstream Process Development Scientist jobs?

Cities in Tennessee with the most Full Time Downstream Process Development Scientist job openings:

Full Time Downstream Process Development Scientist jobs near you
Infographic showing various Full Time Downstream Process Development Scientist job openings in Tennessee as of August 2026, with employment types broken down into 1% As Needed, 81% Full Time, 15% Part Time, and 3% Contract. Highlights an 92% Physical, 2% Hybrid, and 6% Remote job distribution.

Senior Technology Transfer MS&T Engineer

Nashville, TN

August Bioservices
Pharmaceutical and Medicine Manufacturing • 51 - 200 employees
Learn more about August Bioservicesexternal

$100K - $129K/yr

Full-time

Re-posted 6 days ago

Key responsibilities

  • Review technology transfer documents and provide technical analysis of the overall process.

  • Identify gaps in capabilities for new product/process introductions and recommend solutions.

  • Lead evaluations of data during development and scale-up activities and support process optimization.

Job description

Headquartered in Nashville, TN – one of the fastest-growing and most exciting cities in the United States – August Bioservices is a privately-owned, high-growth, and high-impact Contract Development Manufacturing Organization (CDMO).  As a US-based outsourcing partner that provides a wide array of expert drug discovery, drug formulation, and drug manufacturing services to pharma and biotech companies of all sizes, we play a vital role in the global pharmaceutical industry. Our work is instrumental in helping to develop molecules today that can become the life-changing therapies of tomorrow. To support our growth plans, August is investing significant capital in a two-phase expansion project – including building a new state-of-the-art facility adjacent to our current facility. For those seeking dynamic opportunities, rewarding career paths and a chance to make a difference in global health, come grow with August!

August Bioservices is seeking a Technology Transfer MS&T Engineer (Technical Services) reporting to the Sr. Director of Technical Operations. The candidate will serve as a Technical Services expert for aseptic process implementations and is a core team member for customer facing collaborations. An extensive understanding of pharmaceutical sterile processing principles, process development and scale-up approaches is required. Knowledge and expertise in Biologics are preferred with experience in single-use system (SUS) technologies and compliant process segregation as an important core service August Bioservices provides to clients. Technical understanding and application of current equipment, process controls, identification of support utilities and sampling technologies is an important competency as they relate to development, optimization, and technology transfer of small and large molecule fill/finish operations.
 
The incumbent is responsible for tasks associated with the technology transfer for sterile drug products and Biologics. The responsibilities include working with Formulation Development, Process Engineers, Analytical Development, Production, Quality, and Regulatory to identify product and process criticalities and finding scientific data driven solutions to any Technology Transfer process.
 
In Addition, the individual in this role is responsible for working on multiple client-based projects in a fast-paced environment. Apart from Technology Transfer activities, the position requires writing of technical documents to support, including protocols, reports, SOPs, Work Instruction, Batch records, and technical and risk assessments. The Engineer in this role is expected to work with other Technology technical services/process engineers to support process development within a team-based environment. This position will be responsible for participating in interdisciplinary teams and primary contact for the operations team throughout the product’s lifecycle. The Engineer is supported directly by facility engineers as required.
 
Responsibilities
  • Review of technology transfer documents such as product development reports, batch manufacturing and/or packaging records to provide the technical analysis for the overall process.
  • Based on analysis, identify gaps in capabilities needed to support new product/process introductions and recommend solutions to close these gaps.
  • Lead evaluations of collected data during development and scale-up activities and recommend opportunities for process optimization
  • Lead training and familiarization efforts for new processes and equipment including development of operation SOP and work instructions
  • Lead and/or support execution of Toxicological, Clinical, Scale up, Exhibit/Registration, Commercial and process Performance Qualification with production team inside production areas.
  • Lead the evaluation and selection of new equipment in support of fill/finish production operations in collaboration with client and internal stakeholders.
  • Work with R&D, Facilities and Validation team on process implementation to develop a detailed plan based on the approved scope of work
  • Participate in multidisciplinary project teams through the complete product transfer to support ongoing client projects on-time
  • Conduct phase specific studies based on DOE (Design of Experiments) as needed, for formulation optimization and process confirmation.
  • Incorporate Quality-By-Design (QbD) approach in the product development program to improve the drug formulation and manufacturing process.
  • Investigations and Corrective Actions analysis and support.
  • Write comprehensive technical reports, business evaluations, process description with or without supervision.
  • Write documents including master batch records, protocols and reports, SOPs, Work Instructions, and other necessary technical documents.
  • Troubleshoot and resolve simple to moderately complex issues, diagnosing technical problems and identifying short and long-term solutions
  • Working with Cross-Functional Team leads to identifying opportunities for enhancements and champion projects which will improve overall site function.
  • Proficient in Quality system software such as Master control and related task such MOC (change control), CAPA, Issue Reviews, Work Orders, collaboration, and approval of various documents. 
Education
  • The candidate requires B.S in Pharmaceutical Sciences (or equivalent), M.S in Pharmaceutical Sciences (or equivalent), or PhD in Pharmaceutical Sciences (or equivalent).
  • 5+ years of equivalent experience
  • Experience in Pharmaceutical aseptic process implementation including new equipment, sterile filtration, Sterilize-in-Place principles, product dosing technologies and GMP fundamentals in production environments
  • Experience in developing technical recommendations in support of new process introductions
Additional Skills
  • Knowledge of High-Pressure Homogenization, Rotary Evaporators, High Shear Homogenizers, Microfluidizers, Extrusion, Lyophilization, PFS, Vial filling operations, etc.
  • Knowledge of pharmaceutical processing technologies such as mixers, transfer pumps, temperature control devices
  • Knowledge of appropriate process requirements for sterile operations including: compounding, sterile filtration, aseptic formulation, sterile filling for vials, pre-filled syringes and flexible IV bags
  • Software
  • Minitab® (or equivalent), Microsoft Office® etc. 
Phyiscal Requirements
ADA Accommodation Notice
The physical demands described here are representative of those that must be met by an employee to successfully perform the essential functions of this job. Reasonable accommodations may be made to enable individuals with disabilities to perform the essential functions.
 
Physical Requirements
  • Ability to safely wear and work in a PAPR hood and associated equipment weighing approximately 2 to 3 pounds during assigned tasks.
  • Ability to perform sustained physical activities, including standing, walking, bending, reaching, lifting, and handling manufacturing equipment while wearing required respiratory protection and personal protective equipment (PPE).
  • Ability to wear and operate a Powered Air-Purifying Respirator (PAPR) for extended periods, up to 4 to 6 hours per shift, while performing manufacturing, equipment cleaning, and sanitization activities.
  • Ability to wear required PPE, including pharmaceutical gowning, respiratory protection, safety glasses, chemical-resistant gloves, and additional protective equipment as required by operational and safety procedures.

  • Regularly required to stand and walk for extended periods on hard warehouse and production flooring throughout the shift. 

  • Frequently required to bend, stoop, kneel, and reach in both upward and downward directions. 

  • Must be able to occasionally lift and/or move up to 50 lbs; frequently lift and/or move up to 40 lbs; and constantly reposition or transfer objects of negligible weight. 

  • Must be able to push and pull loaded carts, pallet jacks, and hand trucks across production and warehouse surfaces. 

  • Required to safely climb ladders to access materials stored at height. 

  • Must be able to operate powered industrial equipment including forklifts and electric pallet jacks, including the physical demands associated with vibration exposure and repetitive upper-body movement. 

  • Required to work in varying temperature environments, including ambient, refrigerated, and frozen storage areas, using appropriate PPE. 

  • Must be able to wear and work in full cleanroom gowning (including gown, gloves, mask, hairnet, and shoe covers) for extended periods as required by the production area. 

  • Specific vision requirements include close vision, distance vision, peripheral vision, depth perception, and the ability to read small print on labels and batch documents. 

At August Bioservices, Our Credo is our culture. Everything we do, we do with great care. We believe in the promise of discovery and the power of science to transform lives. We assert that excellence is not a static destination, but a standard, and an every-day measuring stick of our advancement. We aspire to unlock the potential in every person, every process and every molecule – from start to finish. We are committed to doing the right thing the first time and every time, meeting or exceeding all regulatory requirements. We strive to be exceptional, preferred and indispensable partners for our customers; responsible and engaged citizens within our communities; and active, mindful stewards of our environment.
 
We are August Bioservices. We are pointing the way forward. If this sounds like your kind of working environment, we want you on our team!

August Bioservices  is an equal opportunity employer and values diversity. All aspects of employment including the decision to hire, promote, discipline, or discharge, will be based on merit, competence, performance, and business needs. August Bioservices does not discriminate on the basis of any status protected under federal, state, or local law.

We may use artificial intelligence (AI) tools to support parts of the hiring process, such as reviewing applications, analyzing resumes, or assessing responses and identifying potential inconsistencies or verification signals in application materials based on available information. These tools assist our recruitment team but do not replace human judgment. Final hiring decisions are ultimately made by humans. If you would like more information about how your data is processed, please contact us.