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Entry Level Protein Purification Scientist Jobs (NOW HIRING)

Bench Scientist

Pearl River, NY · On-site

$36.25 - $45.50/hr

Bench level experience with protein purification, synthetic organic chemistry and/or protein isolation, purification is desirable but not expected. Qualifications BS OR MS Additional Information Best ...

Master's degree in a related scientific discipline Required Technical Experience * Hands-on protein purification experience * Experience operating AKTA chromatography systems * Experience with ...

Demonstrated strong scientific and technical knowledge in protein purification, protein characterization and material characterization techniques, statistical data analysis, technical writing and ...

Demonstrated strong scientific and technical knowledge in protein purification, protein characterization and material characterization techniques, statistical data analysis, technical writing and ...

Research Scientist I; Protein Science in Buffalo, NY Build your future at Curia, where our work has ... Molecular biology, mammalian cell culture, insect cell culture, microbiology, protein purification ...

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Entry Level Protein Purification Scientist information

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How much do entry level protein purification scientist jobs pay per hour?

As of Jun 17, 2026, the average hourly pay for entry level protein purification scientist in the United States is $33.06, according to ZipRecruiter salary data. Most workers in this role earn between $21.63 and $40.87 per hour, depending on experience, location, and employer.

What are some common challenges faced by entry level protein purification scientists, and how can they be overcome?

Entry level protein purification scientists often encounter challenges such as optimizing protocols for different proteins, troubleshooting unexpected results, and managing multiple experiments simultaneously. It is common to face issues with low protein yield or purity, which requires careful adjustment of buffer conditions and purification methods. Collaborating closely with experienced colleagues and utilizing detailed lab documentation can help overcome these hurdles. Additionally, proactively seeking feedback and participating in team meetings fosters continuous learning and improvement.

What does an Entry Level Protein Purification Scientist do?

An Entry Level Protein Purification Scientist is responsible for isolating and purifying proteins from various biological samples using techniques such as chromatography and centrifugation. They assist with preparing buffers and reagents, operating laboratory equipment, and analyzing samples for purity and concentration. Their work supports research, drug development, and manufacturing processes by ensuring proteins are available in the required quality and quantity for further study or production.

What is the difference between Entry Level Protein Purification Scientist vs Laboratory Technician?

AspectEntry Level Protein Purification ScientistLaboratory Technician
Required CredentialsBachelor's degree in Biochemistry, Molecular Biology, or related fieldBachelor's degree or associate degree in a science-related field
Work EnvironmentResearch labs, biotech companies, pharmaceutical firmsResearch, clinical, or industrial labs
Employer & Industry UsageUsed in biotech, pharma, research institutionsCommon in healthcare, research, manufacturing
Common Search & ComparisonOften compared for entry-level research roles involving protein workCompared for lab support roles in similar settings

While both roles work in laboratory settings and may require similar educational backgrounds, the Entry Level Protein Purification Scientist focuses specifically on isolating and analyzing proteins, often involving more specialized techniques. The Laboratory Technician typically supports various lab functions, including sample preparation and data recording, with a broader scope of responsibilities.

What are the key skills and qualifications needed to thrive as an Entry Level Protein Purification Scientist, and why are they important?

To thrive as an Entry Level Protein Purification Scientist, you need a solid background in biochemistry, molecular biology, or related fields, often supported by a bachelor's or master's degree. Familiarity with laboratory techniques such as chromatography, SDS-PAGE, and relevant analytical instruments, as well as experience with lab management software, is typically required. Attention to detail, problem-solving abilities, and effective teamwork are crucial soft skills for success in this role. These skills ensure accurate experimental results, efficient workflow, and reliable contributions to larger research or production goals.
More about Entry Level Protein Purification Scientist jobs
What cities are hiring for Entry Level Protein Purification Scientist jobs? Cities with the most Entry Level Protein Purification Scientist job openings:
What are the most commonly searched types of Protein Purification Scientist jobs? The most popular types of Protein Purification Scientist jobs are:
What states have the most Entry Level Protein Purification Scientist jobs? States with the most job openings for Entry Level Protein Purification Scientist jobs include:

Senior Research Scientist for Biochemistry (Drug Discovery & Assay Development) - (W2 Only)

Sovereign Technologies

Wilmington, DE

$95K - $121K/yr

Other

Posted 7 days ago


Job description

Job Title: Senior Research Scientist – Biochemistry (Drug Discovery & Assay Development)

Location: Wilmington, DE (Onsite)

< data-start=133 data-end=153>Job Description

We are seeking a highly motivated Senior Research Scientist – Biochemistry to join our drug discovery team in Wilmington, DE. The successful candidate will play a key role in designing, developing, and executing biochemical and biophysical assays to support hit identification, validation, lead optimization, and mechanistic studies across multiple therapeutic programs.

This position requires strong expertise in assay development, enzymology, protein characterization, and data analysis within a fast-paced research environment.

Key Responsibilities
  • Design, develop, optimize, and execute biochemical assays including FI, HTRF, FP, and enzyme-based assays.
  • Develop and perform biophysical assays such as SPR, BLI, ITC, and DSF to characterize molecular interactions.
  • Conduct high-throughput screening (HTS) campaigns and analyze compound activity data.
  • Determine binding and kinetic parameters including IC50, EC50, Kd, kon, and koff values.
  • Support hit identification, hit validation, mechanism-of-action studies, and lead optimization efforts.
  • Troubleshoot assay performance and implement improvements to enhance robustness, reproducibility, and scalability.
  • Express, purify, and characterize proteins using affinity, ion-exchange, and size-exclusion chromatography techniques.
  • Analyze experimental data using GraphPad Prism, Genedata, or similar scientific software.
  • Operate and maintain laboratory instrumentation including plate readers, liquid handling systems, and assay automation platforms.
  • Maintain accurate experimental records using electronic laboratory notebooks (ELN).
  • Prepare technical reports, presentations, and scientific summaries for cross-functional project teams.
Required Qualifications
  • Bachelor''''s, Master''''s, or Ph.D. in Biochemistry, Chemistry, Biophysics, Chemical Biology, or a related scientific discipline.
  • Strong foundation in enzymology and biochemical assay development.
  • Hands-on experience with biochemical and biophysical assay platforms.
  • Experience with protein purification and characterization techniques.
  • Knowledge of HTS workflows and compound screening processes.
  • Proficiency with GraphPad Prism, Genedata, or equivalent data analysis tools.
  • Strong analytical, troubleshooting, and problem-solving skills.
  • Excellent documentation, communication, and collaboration abilities.
Preferred Qualifications
  • Industry experience supporting drug discovery programs.
  • Experience with small molecule therapeutics.
  • Familiarity with laboratory automation and liquid handling systems.
  • Knowledge of protein-ligand interaction studies and kinetic analysis.
  • Experience working in pharmaceutical or biotechnology environments.
Must-Have Skills
  • Assay Development
  • Enzymology
  • HTRF / FP / FI Assays
  • SPR / BLI / ITC / DSF
  • High-Throughput Screening (HTS)
  • Protein Purification
  • Chromatography
  • GraphPad Prism
  • Drug Discovery
  • Biochemistry Research