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Downstream Process Jobs in Seattle, WA (NOW HIRING)

Senior Scientist, Cell Science

Redmond, WA ยท On-site

$90K - $140K/yr

Collaborate with project teams and downstream process development scientists to execute protocols, experimental plans, critical production batches, and technology transfers. * Manage and prioritize ...

Senior Scientist, Cell Science

Redmond, WA ยท On-site

$90K - $140K/yr

Collaborate with project teams and downstream process development scientists to execute protocols, experimental plans, critical production batches, and technology transfers. * Manage and prioritize ...

Sr. Process Engineer

Tacoma, WA ยท On-site

$111K - $143K/yr

Senior Process Engineer The Opportunity * Senior Process Engineer at a Growth-Oriented Energy ... We have built a team of downstream industry veterans and subject matter experts to lead our ...

Manage stakeholders and user groups to determine downstream impacts of process, or system changes * Create and maintain key documentation such as process flows, playbooks, and RACIs, while keeping ...

Provide expert guidance across biologics development including upstream and downstream process development, analytical characterization, drug substance and drug product manufacturing, and CMC ...

Showing results 21-40

Downstream Process information

See Seattle, WA salary details

$15

$28

$40

How much do downstream process jobs pay per hour?

As of Aug 8, 2026, the average hourly pay for downstream process in Seattle, WA is $28.08, according to ZipRecruiter salary data. Most workers in this role earn between $22.45 and $32.02 per hour, depending on experience, location, and employer.

What are some common challenges faced by professionals working in downstream process roles?

Professionals in downstream process roles often encounter challenges such as optimizing purification steps to maximize yield and product purity while minimizing costs and processing time. They must also troubleshoot issues related to equipment performance, scalability, and regulatory compliance, especially when transitioning from lab-scale to large-scale production. Collaboration with upstream teams, quality assurance, and engineering is critical to address these challenges and ensure a smooth workflow. Staying current with technological advances and regulatory requirements also plays a significant role in day-to-day success.

What are the key skills and qualifications needed to thrive as a downstream process engineer?

To thrive as a Downstream Process Engineer, you need a solid background in chemical or biochemical engineering, knowledge of purification techniques, and typically a relevant degree. Familiarity with process control systems, chromatography, filtration technologies, and GMP compliance, as well as certifications like Six Sigma, are commonly required. Strong problem-solving, teamwork, and communication skills help you excel in cross-functional teams and address complex production challenges. These skills ensure efficient, high-quality product recovery and compliance with industry standards in biomanufacturing environments.

What is the difference between Downstream Process vs Upstream Process?

AspectDownstream ProcessUpstream Process
PurposePurifies and isolates the target product from the mixtureProduces the initial product, such as cell culture or fermentation
ActivitiesFiltration, chromatography, centrifugation, purificationCell growth, fermentation, media preparation
Work EnvironmentLaboratories, bioprocessing facilitiesBioreactors, fermentation tanks, labs
Required SkillsBioprocessing techniques, chromatography, filtrationMicrobiology, cell culture, fermentation technology

Downstream Process focuses on purifying the product, while Upstream Process involves producing the raw material. Both are essential steps in biopharmaceutical manufacturing, often working sequentially to ensure high-quality product output.

What is a downstream process?

A Downstream Process refers to the series of steps involved in the purification and recovery of biological products, such as proteins, enzymes, or antibodies, after they have been produced by microorganisms or cells during fermentation or cell culture. It typically includes cell separation, product isolation, purification, and polishing to achieve the desired product quality and purity. Downstream processing is crucial for ensuring that biopharmaceutical products meet regulatory and safety standards before they reach the market.
What are popular job titles related to Downstream Process jobs in Seattle, WA? For Downstream Process jobs in Seattle, WA, the most frequently searched job titles are:
What cities near Seattle, WA are hiring for Downstream Process jobs? Cities near Seattle, WA with the most Downstream Process job openings:
Infographic showing various Downstream Process job openings in Seattle, WA as of August 2026, with employment types broken down into 1% As Needed, 80% Full Time, 15% Part Time, and 4% Contract. Highlights an 92% Physical, 2% Hybrid, and 6% Remote job distribution, with an average salary of $58,402 per year, or $28.1 per hour.

BigData Expert/Developer - Locals only - Redmond, WA - Full Time

krg technology inc

Redmond, WA โ€ข On-site

$59.25 - $77/hr

Full-time

Re-posted 20 days ago


Job description

Company Description

Thanks & Regards

Balaji Bobby

KRG Technologies, Inc.,

661 367 8000 Ext :251




Job Description

Build the Event Hubs integration with Service Fabric micro services implementation. Streaming the processed files from blobs into EH for downstream processing.

Anonymized files (~1000 of them and to a size of ~GB) will be given as input

Service Fabric code portion will be provided.

Build the Spark processing reading off EventHubs, implementation in either Python or Scala would suffice.

Look at the caching needs; leverage .cache to retain appropriate results from Spark 'Actions' in Spark executors

Our team will evaluate a set of data store that would be a landing spot post Spark - Blobs being a required one. We will pick 1 or 2 from this list -- SQL DW, Azure SQL DB, Cassandra and DocumentDB being other candidate stores and we will have code snippets and/or guidance

on latency, throughout with percentiles.

Leverage APM tools as appropriate

Qualifications

Locals only - Redmond, WA

Additional Information

Client - HCL America Inc / MicroSoft



KRG Technologies logo

About KRG Technologies

Sourced by ZipRecruiter

KRG Technologies was founded with a simple motive of offering the clients exactly what they want, how they want and when they want. By leveraging for its clients its technological edge and right-sourcing advantage, KRG in a short period of time has grown to become one of the most trusted strategic technology partners. Treating every client as the top priority, we customize our solutions and services to align with the unique needs of each client. Headquartered in Valencia, California, KRG employs a unique global delivery platform to minister its offerings spanning from application development and maintenance to business process reengineering. With years of hands-on domain experience and international presence, we offer state-of-the-art solutions backed by our follow-the-sun service model in the most cost effective manner. We value our clientele for the trust reposed in us and our clientele admire us for our personalized approach and deep commitment to their success. Our biggest strength lies in technical expertise of our team and individual competency of our employees, which enables us to be the most befitting solution provider.

Industry

It services

Company size

201 - 500 Employees

Headquarters location

Valencia, CA, US

Year founded

2003

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