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Downstream Process Jobs in Cleveland, OH (NOW HIRING)

Howmet

Process Engineer

Cleveland, OH · On-site

Responsible for understanding downstream product quality as it relates to die-making and react appropriately to observed conditions. * Will routinely review process for adherence to established ...

Howmet Aerospace

Process Engineer

Cleveland, OH

Responsible for understanding downstream product quality as it relates to die-making and react appropriately to observed conditions. * Will routinely review process for adherence to established ...

Howmet Aerospace

Process Engineer

Cleveland, OH

Responsible for understanding downstream product quality as it relates to die-making and react appropriately to observed conditions. * Will routinely review process for adherence to established ...

Howmet Aerospace Inc.

Process Engineer

Cleveland, OH · On-site

$80 - $100/hr

Responsible for understanding downstream product quality as it relates to die-making and react appropriately to observed conditions. * Will routinely review process for adherence to established ...

Howmet

Process Engineer

Cleveland, OH · On-site

Responsible for understanding downstream product quality as it relates to die-making and react appropriately to observed conditions. * Will routinely review process for adherence to established ...

Howmet Aerospace

Process Engineer

Cleveland, OH · On-site

Responsible for understanding downstream product quality as it relates to die-making and react appropriately to observed conditions. * Will routinely review process for adherence to established ...

Howmet Aerospace

Process Engineer

Cleveland, OH

Responsible for understanding downstream product quality as it relates to die-making and react appropriately to observed conditions. * Will routinely review process for adherence to established ...

Howmet Aerospace

Process Engineer

Brecksville, OH · On-site

$80 - $100/hr

Responsible for understanding downstream product quality as it relates to die-making and react appropriately to observed conditions. * Will routinely review process for adherence to established ...

Cleveland--cliffs-1

Process Control Engineer

Cleveland, OH · On-site

$80 - $100/hr

... downstream finishing, stamping, tooling, and tubing. We offer an excellent total compensation ... process, please send an e-mail to careers@clevelandcliffs.com or call 1-(312) 899-3097 and let us ...

Keybank

Senior Quality Lead

Brooklyn, OH · Hybrid

Experience with enterprise data, data integration, batch processing, interface testing, or downstream data consumption. * Experience coordinating testing across multiple applications, TLAs ...

KeyBank

Senior Quality Lead

Brooklyn, OH · On-site

Experience with enterprise data, data integration, batch processing, interface testing, or downstream data consumption. * Experience coordinating testing across multiple applications, TLAs ...

KeyCorp

Senior Quality Lead

Brooklyn, OH · On-site

$100 - $125/hr

Experience with enterprise data, data integration, batch processing, interface testing, or downstream data consumption. * Experience coordinating testing across multiple applications, TLAs ...

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Downstream Process information

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How much do downstream process jobs pay per hour?

As of Sep 7, 2026, the average hourly pay for downstream process in Cleveland, OH is $23.93, according to ZipRecruiter salary data. Most workers in this role earn between $19.13 and $27.26 per hour, depending on experience, location, and employer.

What is a downstream process?

A Downstream Process refers to the series of steps involved in the purification and recovery of biological products, such as proteins, enzymes, or antibodies, after they have been produced by microorganisms or cells during fermentation or cell culture. It typically includes cell separation, product isolation, purification, and polishing to achieve the desired product quality and purity. Downstream processing is crucial for ensuring that biopharmaceutical products meet regulatory and safety standards before they reach the market.

What are the key skills and qualifications needed to thrive as a downstream process engineer?

To thrive as a Downstream Process Engineer, you need a solid background in chemical or biochemical engineering, knowledge of purification techniques, and typically a relevant degree. Familiarity with process control systems, chromatography, filtration technologies, and GMP compliance, as well as certifications like Six Sigma, are commonly required. Strong problem-solving, teamwork, and communication skills help you excel in cross-functional teams and address complex production challenges. These skills ensure efficient, high-quality product recovery and compliance with industry standards in biomanufacturing environments.

What are some common challenges faced by professionals working in downstream process roles?

Professionals in downstream process roles often encounter challenges such as optimizing purification steps to maximize yield and product purity while minimizing costs and processing time. They must also troubleshoot issues related to equipment performance, scalability, and regulatory compliance, especially when transitioning from lab-scale to large-scale production. Collaboration with upstream teams, quality assurance, and engineering is critical to address these challenges and ensure a smooth workflow. Staying current with technological advances and regulatory requirements also plays a significant role in day-to-day success.

What is the difference between Downstream Process vs Upstream Process?

AspectDownstream ProcessUpstream Process
PurposePurifies and isolates the target product from the mixtureProduces the initial product, such as cell culture or fermentation
ActivitiesFiltration, chromatography, centrifugation, purificationCell growth, fermentation, media preparation
Work EnvironmentLaboratories, bioprocessing facilitiesBioreactors, fermentation tanks, labs
Required SkillsBioprocessing techniques, chromatography, filtrationMicrobiology, cell culture, fermentation technology

Downstream Process focuses on purifying the product, while Upstream Process involves producing the raw material. Both are essential steps in biopharmaceutical manufacturing, often working sequentially to ensure high-quality product output.

What are popular job titles related to Downstream Process jobs in Cleveland, OH?

For Downstream Process jobs in Cleveland, OH, the most frequently searched job titles are:

What job categories do people searching Downstream Process jobs in Cleveland, OH look for?

The top searched job categories for Downstream Process jobs in Cleveland, OH are:

What cities near Cleveland, OH are hiring for Downstream Process jobs?

Cities near Cleveland, OH with the most Downstream Process job openings:

Downstream Process jobs near you
Infographic showing various Downstream Process job openings in Cleveland, OH as of August 2026, with employment types broken down into 1% As Needed, 78% Full Time, 16% Part Time, 4% Contract, and 1% Nights. Highlights an 92% Physical, 2% Hybrid, and 6% Remote job distribution, with an average salary of $49,770 per year, or $23.9 per hour.

Profile Extrusion Process Operator

SpringSeal Industrial Solutions

Ravenna, OH • On-site

$20 - $30/hr

Other

Medical, Dental, Vision, Life, Retirement, PTO

Posted 11 days ago

Job description

Craft profiles with purpose

Imagine dialing in a Davis-Standard, selecting a 3 inch die, and watching a perfect profile emerge as downstream pullers and winders keep pace. At SpringSeal, Inc., that is the craft you will practice on our second and third shift profile lines.

Your mission

Own the process from setup to finished coil. You will configure the extruder, select dies between 2 and 4.5 inches, tune parameters, and guide material through downstream finishing while verifying that every dimension matches the print.

Key responsibilities
  • Set up and operate complete profile extrusion lines using Welex, NRM, Davis-Standard, and American Kuhne equipment.
  • Install dies, establish line settings, and stabilize processes for repeatability.
  • Run downstream equipment: pullers, cutters, winders, printers, and welders.
  • Operate Vulcan, Goodman, CDS, and RDN downstream systems and make in-process adjustments.
  • Use calipers and micrometers to check dimensions; verify against simple prints and work instructions.
What you will need
  • Minimum 2 years of profile extrusion experience.
  • Proficiency with precision measurement, blueprint reading, shop math, and following instructions.
  • Personal tools suitable for setup and adjustment tasks.
Compensation and benefits
  • Health insurance with prescription drug benefit
  • Life Insurance, ADD and Short Term Disability
  • Dental and Vision Insurance
  • 401(k) with a 3 percent company contribution of gross wage
  • Vacation and PTO
Proficiencies
  • Precision measurement and hand metrology
  • Plastic extrusion experience
  • Shop math skills
  • Blueprint reading
Machines & technologies you'll use
  • Extrusion Machine

If you take pride in stable runs, crisp cuts, and profiles that measure exactly as intended, you will thrive here.