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Downstream Process Jobs in Virginia (NOW HIRING)

Business Process Analyst

Richmond, VA

$60.40K - $81.10K/yr

... downstream usage. * Testing & validation: Support SIT/UAT planning and execution; develop test ... Maintain process documentation, requirements traceability, and decision logs; support audits and ...

Depth Capture edge cases, data conditions, dependencies, and downstream impacts. * Process Mapping: Create workflow diagrams using Visio or equivalent. * Clarity & Accuracy: Ensure documentation is ...

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Downstream Process information

What are the key skills and qualifications needed to thrive as a Downstream Process Engineer, and why are they important?

To thrive as a Downstream Process Engineer, you need a solid background in chemical or biochemical engineering, knowledge of purification techniques, and typically a relevant degree. Familiarity with process control systems, chromatography, filtration technologies, and GMP compliance, as well as certifications like Six Sigma, are commonly required. Strong problem-solving, teamwork, and communication skills help you excel in cross-functional teams and address complex production challenges. These skills ensure efficient, high-quality product recovery and compliance with industry standards in biomanufacturing environments.

What are some common challenges faced by professionals working in downstream process roles within biomanufacturing?

Professionals in downstream process roles often encounter challenges such as optimizing purification steps to maximize yield and product purity while minimizing costs and processing time. They must also troubleshoot issues related to equipment performance, scalability, and regulatory compliance, especially when transitioning from lab-scale to large-scale production. Collaboration with upstream teams, quality assurance, and engineering is critical to address these challenges and ensure a smooth workflow. Staying current with technological advances and regulatory requirements also plays a significant role in day-to-day success.

What is a Downstream Process in biotechnology?

A Downstream Process refers to the series of steps involved in the purification and recovery of biological products, such as proteins, enzymes, or antibodies, after they have been produced by microorganisms or cells during fermentation or cell culture. It typically includes cell separation, product isolation, purification, and polishing to achieve the desired product quality and purity. Downstream processing is crucial for ensuring that biopharmaceutical products meet regulatory and safety standards before they reach the market.

What is the difference between Downstream Process vs Upstream Process?

AspectDownstream ProcessUpstream Process
PurposePurifies and isolates the target product from the mixtureProduces the initial product, such as cell culture or fermentation
ActivitiesFiltration, chromatography, centrifugation, purificationCell growth, fermentation, media preparation
Work EnvironmentLaboratories, bioprocessing facilitiesBioreactors, fermentation tanks, labs
Required SkillsBioprocessing techniques, chromatography, filtrationMicrobiology, cell culture, fermentation technology

Downstream Process focuses on purifying the product, while Upstream Process involves producing the raw material. Both are essential steps in biopharmaceutical manufacturing, often working sequentially to ensure high-quality product output.

Infographic showing various Downstream Process job openings in Virginia as of May 2026, with employment types broken down into 2% Internship, 90% Full Time, 2% Temporary, 4% Contract, and 2% Nights. Highlights an 96% In-person, and 4% Remote job distribution.

Job description

The GRC Process Architect will work in the Security Architecture & Engineering team in the CISO organization. This role is responsible for designing, optimizing, and documenting processes that integrate Security, IT Change Management, and GRC workflows. This role plays a critical part in maturing the organization's compliance posture by enabling automated traceability between IT changes, affected environments, and required updates to compliance and security controls"

The role will require:
(1) Working with Information Security to identify fragmented data points across existing processes and design integrated, end-to-end data flows
(2) Ability to Analyze, design and document business processes with a GRC context, with focus on traceability from Change requests to impacted environments and CMMC controls
(3) Building workflow designs that enrich and map data across ServiceNow modules, enabling consistent downstream impact analysis for security and compliance
(4) Active Collaboration with a variety of different teams within IT and IS to ensure a robust and complete solution
(5) General Knowledge of Federal Regulatory Compliance Controls such as NIST 800-53, NIST 800-171, CMMC, etc.
(6) Understanding of IT Change Management Practices 

The work

  • Understand current Security processes and how they align to CMMC Controls
  • Design workflows that will enrich data points for downstream processes and impact analysis
  • Collaborate with IT development teams to translate process designs into technical implementation within the ServiceNow platform.  
  • Build and document end-to-end workflows to solve current gaps in Security and Compliance Processes
  • Produce clear, comprehensive process documentation to support operational excellence, audit readiness, and automation.

What you need

  • U.S. Citizen (required).  
  • 5+ years of experience in business process design or process architecture.  
  • Working knowledge of CMMC regulatory compliance controls (NIST 800-171).  
  • Strong familiarity with GRC processes and successful GRC tool implementations.  
  • Understanding of IT Change Management practices and data governance.  
  • Experience working with or designing AI-enabled or automation workflows that enhance process efficiency.

Bonus if you have

  • Prior handson experience with ServiceNow GRC/IRM modules.  
  • Relevant certifications such as CPDP, CPDE, or equivalent experience.  
  • Experience working within an Agile delivery or development framework.  
  • Background supporting Information Security and Compliance teams