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Downstream Process Jobs in Kentucky (NOW HIRING)

Avid Bioservices, Inc.

$75 - $95/hr

The Supervisor, Manufacturing Downstream is responsible for the supervision of Downstream ... Oversee the setup of new manufacturing processes and critical equipment. * Identify the technical ...

New

Mohawk Industries, Inc.

$70 - $95/hr

Work hand-in-hand with production, maintenance, quality, automation, R&D, and upstream/downstream process teams to improve process stability, reliability, product performance, and cost.

Partner's Consulting, Inc.

$110 - $160/hr

Business Process Engineer Location: Remote Type: Contract Our direct client is seeking a Business ... a downstream handoff. * Maintain reusable specification templates, standards, glossaries, and ...

Conduent, Inc.

Mailroom Associate

Lexington, KY · On-site

$16/hr

You'll work as part of a team processing incoming mail and preparing documents for imaging and downstream processing. If you enjoy structured work, take pride in doing things correctly, and are ...

Conduent, Inc.

Mailroom Associate

Lexington, KY · On-site

$16/hr

You'll work as part of a team processing incoming mail and preparing documents for imaging and downstream processing. If you enjoy structured work, take pride in doing things correctly, and are ...

Ring Inc

$138 - $162/hr

This is not a downstream execution role. You will proactively influence product and process decisions by leveraging shop floor data, structured experimentation, and lessons learned from production to ...

Serco USA

Business Process Consultant II

London, KY · On-site

As a Business Process Consultant II supporting the CMS Eligibility Support program, you will help ... downstream impacts. * Support User Acceptance Testing (UAT), including development of test ...

Serco USA

Business Process Consultant II

Corbin, KY · On-site

As a Business Process Consultant II supporting the CMS Eligibility Support program, you will help ... downstream impacts. • Support User Acceptance Testing (UAT), including development of test ...

AI Chopping Block

$160 - $190/hr

Strong understanding of downstream sales and revenue processes , including opportunity management, pipeline management, forecasting, quoting, approvals, contracting, and the progression of a deal ...

Rosendin Electric, Inc.

$137 - $180/hr

... downstream processes such as Payroll, Time & Absence, Benefits, Compensation, Performance, Learning and Development, etc. and account for those dependencies in planning and testing. Partner with HR ...

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Downstream Process information

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How much do downstream process jobs pay per hour?

As of Aug 27, 2026, the average hourly pay for downstream process in Kentucky is $21.43, according to ZipRecruiter salary data. Most workers in this role earn between $17.12 and $24.42 per hour, depending on experience, location, and employer.

What is a downstream process?

A Downstream Process refers to the series of steps involved in the purification and recovery of biological products, such as proteins, enzymes, or antibodies, after they have been produced by microorganisms or cells during fermentation or cell culture. It typically includes cell separation, product isolation, purification, and polishing to achieve the desired product quality and purity. Downstream processing is crucial for ensuring that biopharmaceutical products meet regulatory and safety standards before they reach the market.

What are the key skills and qualifications needed to thrive as a downstream process engineer?

To thrive as a Downstream Process Engineer, you need a solid background in chemical or biochemical engineering, knowledge of purification techniques, and typically a relevant degree. Familiarity with process control systems, chromatography, filtration technologies, and GMP compliance, as well as certifications like Six Sigma, are commonly required. Strong problem-solving, teamwork, and communication skills help you excel in cross-functional teams and address complex production challenges. These skills ensure efficient, high-quality product recovery and compliance with industry standards in biomanufacturing environments.

What are some common challenges faced by professionals working in downstream process roles?

Professionals in downstream process roles often encounter challenges such as optimizing purification steps to maximize yield and product purity while minimizing costs and processing time. They must also troubleshoot issues related to equipment performance, scalability, and regulatory compliance, especially when transitioning from lab-scale to large-scale production. Collaboration with upstream teams, quality assurance, and engineering is critical to address these challenges and ensure a smooth workflow. Staying current with technological advances and regulatory requirements also plays a significant role in day-to-day success.

What is the difference between Downstream Process vs Upstream Process?

AspectDownstream ProcessUpstream Process
PurposePurifies and isolates the target product from the mixtureProduces the initial product, such as cell culture or fermentation
ActivitiesFiltration, chromatography, centrifugation, purificationCell growth, fermentation, media preparation
Work EnvironmentLaboratories, bioprocessing facilitiesBioreactors, fermentation tanks, labs
Required SkillsBioprocessing techniques, chromatography, filtrationMicrobiology, cell culture, fermentation technology

Downstream Process focuses on purifying the product, while Upstream Process involves producing the raw material. Both are essential steps in biopharmaceutical manufacturing, often working sequentially to ensure high-quality product output.

What are popular job titles related to Downstream Process jobs in Kentucky?

For Downstream Process jobs in Kentucky, the most frequently searched job titles are:

What job categories do people searching Downstream Process jobs in Kentucky look for?

The top searched job categories for Downstream Process jobs in Kentucky are:

What cities in Kentucky are hiring for Downstream Process jobs?

Cities in Kentucky with the most Downstream Process job openings:

Downstream Process jobs near you
Infographic showing various Downstream Process job openings in Kentucky as of August 2026, with employment types broken down into 1% As Needed, 77% Full Time, 18% Part Time, 3% Contract, and 1% Nights. Highlights an 92% Physical, 2% Hybrid, and 6% Remote job distribution, with an average salary of $44,572 per year, or $21.4 per hour.

Downstream Processing Operator

Danimer Scientific LLC

Winchester, KY • On-site

$16.50 - $20.75/hr

Full-time

Medical, Dental, Vision, Retirement

Re-posted 27 days ago

Job description

Benefits:
  • 401(k)
  • 401(k) matching
  • Bonus based on performance
  • Dental insurance
  • Health insurance
  • Training & development
  • Vision insurance
  • Wellness resources

NOW INTERVIEWING FOR FUTURE OPPORTUNITIES:
Downstream Processing (DSP) Operator
???? Winchester, KY | ???? Biodegradable Plastics
???? Schedule: 12 Hour Shifts on a 2-2-3 pattern (Day or Night Availability Required)
???? Employment Type: Non-exempt | Full-time

At Danimer Scientific, we’re building the future of sustainable materials—and that takes skilled operators who care about quality, safety, and doing things the right way. As a Downstream Processing (DSP) Operator, you’ll play a hands-on role in producing advanced materials in a cGMP manufacturing environment while working with a collaborative, safety-focused team.
If you enjoy technical work, problem-solving, and being part of a process that truly matters, we’d love to meet you.
???? What You’ll Do

Under the guidance of a Team Leader and Manufacturing Management, the DSP Operator is responsible for executing day-to-day production activities in the Downstream Processing area.  This role is hands-on, detail-oriented, and critical to maintaining product quality and process reliability.
Key Responsibilities Include:

  • Operate and monitor downstream processing equipment and utilities
  • Start/stop pumps, open/close manual valves, collect samples, and respond to process alarms
  • Monitor process conditions and adjust parameters to maintain stability
  • Accurately complete batch records, logbooks, and production documentation in compliance with cGMP standards
  • Review production documentation for accuracy, completeness, and quality compliance
  • Add chemicals and process additives based on calculations and procedures
  • Troubleshoot process or equipment deviations and initiate corrective actions
  • Communicate production metrics, issues, and shift handoffs clearly
  • Maintain clean, organized, and audit-ready work areas per GMP standards
  • Participate in continuous improvement initiatives related to safety, quality, and efficiency
  • Train and support new or developing operators
  • Serve as a safety leader—stop production when a quality or safety concern is identified
 ???? What We’re Looking For
Required Qualifications

  • High school diploma or GED
  • Minimum of 2 years of experience in a manufacturing or industrial environment
  • Ability to work independently and as part of a team
  • Strong attention to detail and commitment to documentation accuracy
  • Mechanically inclined with strong problem-solving skills
  • Comfortable working with automated systems and manual equipment
  • Proficient with basic computer systems (Microsoft Suite)
Preferred Qualifications

  • Associate degree in applied process technologies or related field
  • Prior experience in biotech, chemical, or cGMP manufacturing
  • Working knowledge of GMP, safety protocols, and quality systems
 ???? Work Schedule

  • Full-time, 12-hour shifts
  • Days or nights, including weekends, holidays, and overtime as required
 ???? Physical & Work Environment Requirements

  • Ability to stand, walk, bend, stoop, and perform repetitive tasks for extended periods
  • Ability to lift up to 50 lbs occasionally and climb ladders/stairs
  • Work in hot, cold, loud, and industrial manufacturing environments
  • Use of PPE including hearing protection in designated areas
  • Exposure to moving mechanical parts, vibration, fumes, and airborne particles
???? Why Danimer?

✨ Mission-driven work (bye, plastic pollution)
✨ Growth opportunity
✨ Great pay + benefits
✨ Team-first culture
⚖️ Equal Opportunity Employer

Danimer Scientific provides equal employment opportunities to all employees and applicants without regard to race, color, religion, sex, national origin, age, disability, genetics, or any other status protected by law. We comply with all federal, state, and local laws governing nondiscrimination in every location where we operate.
We strictly prohibit any form of workplace harassment or discrimination based on race, color, religion, gender, sexual orientation, gender identity or expression, national origin, age, disability, veteran status, or any other protected status.
Apply now and be part of something bigger.