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Downstream Process Jobs in Delaware (NOW HIRING)

Business Analyst

New Castle, DE · On-site

$60K - $78K/yr

Develop and maintain documentation for system processes, procedures, and deliverables * Ensure ... Conduct root cause analysis and assess downstream impacts * Facilitate and lead design discussions ...

SW Engineer III

Wilmington, DE · On-site

$55.75 - $75/hr

... downstream system integrations. Required details and skill matrix: * Are you currently under ... File-based integrations (SFTP, batch processing) RESTful APIs: SOAP and XQuery-based APIs: File ...

Business Analyst

New Castle, DE · On-site +1

$60K - $78K/yr

Develop and maintain documentation for system processes, procedures, and deliverables * Ensure ... Conduct root cause analysis and assess downstream impacts * Facilitate and lead design discussions ...

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Downstream Process information

What are some common challenges faced by professionals working in downstream process roles within biomanufacturing?

Professionals in downstream process roles often encounter challenges such as optimizing purification steps to maximize yield and product purity while minimizing costs and processing time. They must also troubleshoot issues related to equipment performance, scalability, and regulatory compliance, especially when transitioning from lab-scale to large-scale production. Collaboration with upstream teams, quality assurance, and engineering is critical to address these challenges and ensure a smooth workflow. Staying current with technological advances and regulatory requirements also plays a significant role in day-to-day success.

What are the key skills and qualifications needed to thrive as a Downstream Process Engineer, and why are they important?

To thrive as a Downstream Process Engineer, you need a solid background in chemical or biochemical engineering, knowledge of purification techniques, and typically a relevant degree. Familiarity with process control systems, chromatography, filtration technologies, and GMP compliance, as well as certifications like Six Sigma, are commonly required. Strong problem-solving, teamwork, and communication skills help you excel in cross-functional teams and address complex production challenges. These skills ensure efficient, high-quality product recovery and compliance with industry standards in biomanufacturing environments.

What is the difference between Downstream Process vs Upstream Process?

AspectDownstream ProcessUpstream Process
PurposePurifies and isolates the target product from the mixtureProduces the initial product, such as cell culture or fermentation
ActivitiesFiltration, chromatography, centrifugation, purificationCell growth, fermentation, media preparation
Work EnvironmentLaboratories, bioprocessing facilitiesBioreactors, fermentation tanks, labs
Required SkillsBioprocessing techniques, chromatography, filtrationMicrobiology, cell culture, fermentation technology

Downstream Process focuses on purifying the product, while Upstream Process involves producing the raw material. Both are essential steps in biopharmaceutical manufacturing, often working sequentially to ensure high-quality product output.

What is a Downstream Process in biotechnology?

A Downstream Process refers to the series of steps involved in the purification and recovery of biological products, such as proteins, enzymes, or antibodies, after they have been produced by microorganisms or cells during fermentation or cell culture. It typically includes cell separation, product isolation, purification, and polishing to achieve the desired product quality and purity. Downstream processing is crucial for ensuring that biopharmaceutical products meet regulatory and safety standards before they reach the market.
What are popular job titles related to Downstream Process jobs in Delaware? For Downstream Process jobs in Delaware, the most frequently searched job titles are:
What job categories do people searching Downstream Process jobs in Delaware look for? The top searched job categories for Downstream Process jobs in Delaware are:
Infographic showing various Downstream Process job openings in Delaware as of July 2026, with employment types broken down into 18% Locum Tenens, 74% Full Time, 4% Part Time, 3% Contract, and 1% Summer. Highlights an 85% Physical, 4% Hybrid, and 11% Remote job distribution.
Firmwide Financial Control - Markets Netting Analyst

Firmwide Financial Control - Markets Netting Analyst

JPMorgan Chase & Co

Newark, DE • On-site

Full-time

Medical, Retirement

Re-posted 8 days ago


JPMorgan Chase & Co. rating

8.0

Company rating: 8.0 out of 10

Based on 491 frontline employees who took The Breakroom Quiz

58th of 149 rated banks


Job description

Join JPMorganChase. As a Financial Controller Analyst within the Corporate & Investment Bank (CIB), you will support a specialized function focused on derivatives netting balance sheet controls.

This role designed for individuals interested in building a foundation in financial control, derivatives, and balance sheet management. You will play a key role in ensuring the accuracy, integrity, and timeliness of the Firm's books and records, while gaining exposure to trading products, collateral processes, and financial reporting.

You will work at the intersection of trading activity, collateral infrastructure, and accounting, partnering across teams to deliver high-quality financial control outcomes in a fast-paced, regulated environment.

Job Responsibilities

  • Perform balance sheet reconciliation and substantiation for derivatives, netting-related balances
  • Support controls over derivative netting populations, including validation of agreements, netting sets, and key reporting attributes
  • Investigate and resolve variances between general ledger and upstream systems (trading, operations, collateral platforms)
  • Assist with month-end close activities, including balance sheet certification, variance commentary, and control execution
  • Contribute to quarter-end reporting processes, supporting financial reporting and downstream stakeholders
  • Maintain adherence to General Ledger Reconciliation & Substantiation (GLRS) standards, ensuring timely and accurate documentation
  • Partner with controllers, operations, middle office, and technology teams to understand trade flows and resolve issues
  • Identify opportunities to improve processes, strengthen controls, and reduce manual effort
  • Utilize AI-driven and advanced analytics tools to analyze large datasets, identify patterns in breaks, and support more efficient and insightful financial control processes

Required Qualifications, Skills, and Capabilities

  • Bachelor's degree in Accounting, Finance, Economics, or related field
  • Up to 2 years of relevant experience (internships or entry-level roles in finance, accounting, or operations considered)
  • Basic understanding of accounting concepts and financial statements 
  • Strong analytical and problem-solving skills with attention to detail
  • Ability to work with data in Excel and perform basic analysis
  • Strong written and verbal communication skills
  • Ability to manage multiple priorities and meet deadlines
  • Strong control mindset with focus on accuracy and completeness

  • Eagerness to learn and develop in a financial control environment
  • Ability to analyze issues and escalate appropriately
  • Collaborative approach and ability to work across teams

Preferred Qualifications, Skills, and Capabilities

  • Exposure to financial markets or derivatives products (academic or internship experience)
  • Basic understanding of collateral or margin concepts
  • Experience performing reconciliations or data analysis
  • Interest in process improvement, automation, or data tools
JPMorganChase, one of the oldest financial institutions, offers innovative financial solutions to millions of consumers, small businesses and many of the world's most prominent corporate, institutional and government clients under the J.P. Morgan and Chase brands. Our history spans over 200 years and today we are a leader in investment banking, consumer and small business banking, commercial banking, financial transaction processing and asset management.

We offer a competitive total rewards package including base salary determined based on the role, experience, skill set and location. Those in eligible roles may receive commission-based pay and/or discretionary incentive compensation, paid in the form of cash and/or forfeitable equity, awarded in recognition of individual achievements and contributions. We also offer a range of benefits and programs to meet employee needs, based on eligibility. These benefits include comprehensive health care coverage, on-site health and wellness centers, a retirement savings plan, backup childcare, tuition reimbursement, mental health support, financial coaching and more. Additional details about total compensation and benefits will be provided during the hiring process. 

We recognize that our people are our strength and the diverse talents they bring to our global workforce are directly linked to our success. We are an equal opportunity employer and place a high value on diversity and inclusion at our company. We do not discriminate on the basis of any protected attribute, including race, religion, color, national origin, gender, sexual orientation, gender identity, gender expression, age, marital or veteran status, pregnancy or disability, or any other basis protected under applicable law. We also make reasonable accommodations for applicants' and employees' religious practices and beliefs, as well as mental health or physical disability needs. Visit our FAQs for more information about requesting an accommodation.

JPMorgan Chase & Co. is an Equal Opportunity Employer, including Disability/Veterans

Our professionals in our Corporate Functions cover a diverse range of areas from finance and risk to human resources and marketing. Our corporate teams are an essential part of our company, ensuring that we're setting our businesses, clients, customers and employees up for success.

Global Finance & Business Management works to strategically manage capital, drive growth and efficiencies, maintain financial reporting and proactively manage risk. By providing information, analysis and recommendations to improve results and drive decisions, teams ensure the company can navigate all types of market conditions while protecting our fortress balance sheet.

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