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Downstream Process Jobs in Connecticut (NOW HIRING)

Athene

Senior Analyst, Derivative Operations

Greenwich, CT · On-site

$85K - $128K/yr

Review legal trading documentation (ISDAs, CSAs, MCAs, and related agreements) and ensure accurate trade booking and downstream processing. * Monitor regulatory changes, industry initiatives, and ...

Kemper

Senior Data Systems Analyst

Hartford, CT

Validate data movement across source systems, ETL/ELT processes, data warehouses, reporting environments, and downstream consumers. * Perform system integration testing, user acceptance testing ...

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Downstream Process information

See Connecticut salary details

$12

$23

$33

How much do downstream process jobs pay per hour?

As of Aug 8, 2026, the average hourly pay for downstream process in Connecticut is $23.47, according to ZipRecruiter salary data. Most workers in this role earn between $18.75 and $26.73 per hour, depending on experience, location, and employer.

What are some common challenges faced by professionals working in downstream process roles?

Professionals in downstream process roles often encounter challenges such as optimizing purification steps to maximize yield and product purity while minimizing costs and processing time. They must also troubleshoot issues related to equipment performance, scalability, and regulatory compliance, especially when transitioning from lab-scale to large-scale production. Collaboration with upstream teams, quality assurance, and engineering is critical to address these challenges and ensure a smooth workflow. Staying current with technological advances and regulatory requirements also plays a significant role in day-to-day success.

What are the key skills and qualifications needed to thrive as a downstream process engineer?

To thrive as a Downstream Process Engineer, you need a solid background in chemical or biochemical engineering, knowledge of purification techniques, and typically a relevant degree. Familiarity with process control systems, chromatography, filtration technologies, and GMP compliance, as well as certifications like Six Sigma, are commonly required. Strong problem-solving, teamwork, and communication skills help you excel in cross-functional teams and address complex production challenges. These skills ensure efficient, high-quality product recovery and compliance with industry standards in biomanufacturing environments.

What is the difference between Downstream Process vs Upstream Process?

AspectDownstream ProcessUpstream Process
PurposePurifies and isolates the target product from the mixtureProduces the initial product, such as cell culture or fermentation
ActivitiesFiltration, chromatography, centrifugation, purificationCell growth, fermentation, media preparation
Work EnvironmentLaboratories, bioprocessing facilitiesBioreactors, fermentation tanks, labs
Required SkillsBioprocessing techniques, chromatography, filtrationMicrobiology, cell culture, fermentation technology

Downstream Process focuses on purifying the product, while Upstream Process involves producing the raw material. Both are essential steps in biopharmaceutical manufacturing, often working sequentially to ensure high-quality product output.

What is a downstream process?

A Downstream Process refers to the series of steps involved in the purification and recovery of biological products, such as proteins, enzymes, or antibodies, after they have been produced by microorganisms or cells during fermentation or cell culture. It typically includes cell separation, product isolation, purification, and polishing to achieve the desired product quality and purity. Downstream processing is crucial for ensuring that biopharmaceutical products meet regulatory and safety standards before they reach the market.
What are popular job titles related to Downstream Process jobs in Connecticut? For Downstream Process jobs in Connecticut, the most frequently searched job titles are:
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What cities in Connecticut are hiring for Downstream Process jobs? Cities in Connecticut with the most Downstream Process job openings:
Downstream Process jobs near you
Infographic showing various Downstream Process job openings in Connecticut as of August 2026, with employment types broken down into 1% As Needed, 78% Full Time, 14% Part Time, 3% Temporary, and 4% Contract. Highlights an 91% Physical, 2% Hybrid, and 7% Remote job distribution, with an average salary of $48,819 per year, or $23.5 per hour.

Technical Sales Specialist (Chromatography Resin)

Thermo Fisher Scientific

Groton, CT

Full-time

Posted 15 days ago

Thermo Fisher Scientific rating

7.7

Company rating: 7.7 out of 10

Based on 422 frontline employees who took The Breakroom Quiz

196th of 537 rated manufacturers

Job description

Work Schedule

Standard (Mon-Fri)

Environmental Conditions

Office

Job Description

About the Role 

We seek a Technical Sales Specialist (TSS) who gets inside our customers' purification processes and drives real resin adoption and conversion. In this role, you'll register our chromatography resins into the downstream processes of Korea's leading biopharmaceutical manufacturers and CDMOs, then scale them across clinical and commercial pipelines to build durable, recurring revenue. Your impact is measured not by how well you present, but by whether the customer actually changes their process. 

Key Responsibilities 

1) Lead resin conversion and adoption projects end-to-end 

  • Drive resin conversion projects across every purification mode — Protein A/affinity, ion exchange (IEX), hydrophobic interaction (HIC), multimodal/mixed-mode, and multi-column chromatography (MCC) — from opportunity identification through to registration. 

  • Design and execute the full cycle with the customer: technical evaluation → technical support → pricing → process adaptation → commercial adoption.  

  • Propose purification solutions for emerging chemistries, including bispecifics, complexed mAbs, and next-generation modalities — not just standard mAb platforms. 

  • Develop and execute account-level conversion strategies to accelerate resin adoption and long-term business growth. 

2) Build technically grounded value propositions 

  • Move beyond catalog selling: lower the customer's conversion barrier by packaging performance data, DBC comparisons, documentation, and supply reliability into a compelling technical case. 

  • Translate a wide range of customer needs into the process and cost advantages of our resins. 

  • Support commercial discussions by providing technical justification that strengthens customer confidence and accelerates conversion.  

3) Build cross-functional relationships within the customer 

  • Serve as the technical bridge between process development (PD) and manufacturing (MSAT). Even the strongest proposal is meaningless if the manufacturing floor rejects it, so building MSAT's technical familiarity and confidence to adopt is decisive. 

  • Partner closely with the sales team to jointly build and execute account-level conversion roadmaps. 

  • Collaborate with Product Management, Marketing, and Technical teams to deliver customer-focused solutions and drive successful project execution.  

4) Provide market and technical insight 

  • Read the technical shifts in the purification market — new modalities, competitive resin trends — and feed them back into account strategy. 

  • Collaborate with Product Management, Marketing, and Global Technical teams to deliver customer-focused solutions and drive successful project execution.  

What Success Looks Like 

  • Registering new resins into clinical and commercial pipelines at your accounts, and growing each one into a seed of recurring revenue. 

  • Being recognized by customer MSAT and PD teams as a partner they can technically trust and rely on. 

  • Proactively removing technical conversion risk so the sales team can focus on pricing and commercial negotiation. 

  • Building a strong pipeline of qualified conversion opportunities and contributing to sustainable revenue growth.  

Required Qualifications 

  • Master's degree (or above) in Biochemistry, Biotechnology, Chemical Engineering, Biology, or a related Life Sciences discipline. Bachelor's degree with equivalent industry experience will also be considered.  

  • 3+ years of experience in downstream process development, purification, bioprocess development, MSAT, manufacturing, technical support, or related roles within the biopharmaceutical industry.  

  • Strong understanding of chromatography principles and downstream purification processes.  

  • Excellent communication, presentation, and customer engagement skills.  

  • Ability to collaborate effectively across cross-functional teams.  

  • Business-level English communication skills. 

Preferred Qualifications 

  • Experience with HTS screening (automated platforms such as Tecan and Robocolumn). 

  • Experience purifying mAb platform processes, bispecifics, complexed mAbs, or next-generation modalities. 

  • GMP manufacturing/MSAT experience, or large-scale column packing experience. 

  • An established network across Korea's major biopharmaceutical manufacturers and CDMOs. 

  • Experience gained within biopharmaceutical manufacturers, CDMOs, or chromatography solution providers is highly valued. 

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