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Downstream Process Development Jobs in Rhode Island

Astrix Inc

Biomanufacturing Associate

West Greenwich, RI · On-site

$27.50/hr

Support pilot-scale biopharmaceutical process development and laboratory operations in a regulated ... Support downstream processing activities, which may include chromatography, filtration, and ...

Danaher

Filtration Sales Specialist

Providence, RI · Remote

$100K - $130K/yr

... downstream processing preferred * Strong communication skills - English written and spoken ... Process development with knowledge of clinical workflow * Commercial sales process, preferably in ...

CAI

Validation Engineer

Providence, RI · On-site

$72K - $80K/yr

... processes, and elite expertise developed over 30 years. Our Purpose We exist to be the trusted ... HVAC) - Upstream/downstream processing - Purification, recovery - Building automation ...

CAI

Validation Engineer

Providence, RI · On-site

$72K - $80K/yr

... processes, and elite expertise developed over 30 years. Our Purpose We exist to be the trusted ... HVAC) - Upstream/downstream processing - Purification, recovery - Building automation ...

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Downstream Process Development information

See Rhode Island salary details

$18

$32

$48

How much do downstream process development jobs pay per hour?

As of Sep 9, 2026, the average hourly pay for downstream process development in Rhode Island is $32.99, according to ZipRecruiter salary data. Most workers in this role earn between $27.07 and $40.48 per hour, depending on experience, location, and employer.

What is downstream process development?

A Downstream Process Development job involves optimizing and scaling purification processes for biologics, such as proteins, antibodies, or gene therapies. Scientists and engineers in this role develop efficient methods for isolation, purification, and formulation of therapeutic products while ensuring quality and regulatory compliance. Key activities include chromatography, filtration, and process analytics to improve yield, purity, and consistency. This role is critical in biotech and pharmaceutical industries to ensure safe and effective drug production for clinical and commercial use.

What does someone in downstream process development do?

Professionals in Downstream Process Development are typically responsible for designing, optimizing, and scaling up purification processes for biopharmaceutical products. Their day-to-day work may involve conducting laboratory experiments, analyzing data, troubleshooting technical issues, and documenting process changes in accordance with regulatory standards. They also frequently collaborate with upstream processing, analytical, and quality teams to ensure seamless transfer and integration of processes. The role often includes participating in project meetings, contributing to process validation efforts, and supporting technology transfer to manufacturing teams, making it both technically challenging and collaborative.

What are the key skills and qualifications needed for downstream process development?

To excel in Downstream Process Development, you generally need a strong background in biochemistry, chemical engineering, or a related life sciences field, often with experience in bioprocessing or purification technologies. Familiarity with chromatography systems, filtration equipment, process analytical technology (PAT), and relevant software such as DeltaV or Unicorn is frequently required, along with knowledge of GMP and regulatory standards. Excellent problem-solving, project management, and cross-functional communication skills help professionals succeed in dynamic team environments. These competencies are crucial for developing efficient, scalable purification processes that ensure high product quality and support organizational goals.

What job categories do people searching Downstream Process Development jobs in Rhode Island look for?

The top searched job categories for Downstream Process Development jobs in Rhode Island are:

Downstream Process Development jobs near you
Infographic showing various Downstream Process Development job openings in Rhode Island as of August 2026, with employment types broken down into 1% As Needed, 82% Full Time, 15% Part Time, and 2% Contract. Highlights an 90% Physical, 3% Hybrid, and 7% Remote job distribution, with an average salary of $68,611 per year, or $33 per hour.

Biomanufacturing Associate

West Greenwich, RI • On-site

Astrix Inc
Recruiting and Staffing Services • 1 - 5K employees
Learn more about Astrix Incexternal

$27.50/hr

Full-time

Re-posted 18 days ago

Job description

Pay Rate Low: 22 | Pay Rate High: 27.50
Join a global, science-driven biopharmaceutical organization known for its commitment to quality, patient safety, and operational excellence.
Location: West Greenwich, RI
Schedule: M-F 7:30A-4P, rotating weekends
Pay: Up to $27.50/hr
**Contract Role**
Job Duties
  • Support pilot-scale biopharmaceutical process development and laboratory operations in a regulated environment.
  • Perform upstream cell culture activities, including aseptic vial thawing, flask passaging, and operation of benchtop, wave, and single-use bioreactors.
  • Support downstream processing activities, which may include chromatography, filtration, and ultrafiltration/diafiltration (UF/DF).
  • Prepare media and buffer solutions and assist with in-process sampling and sample management.
  • Operate laboratory analyzers and pilot-scale process equipment while collecting and documenting scientific and process data.
  • Record experimental results and process information using electronic laboratory notebooks and in accordance with Good Documentation Practices.
  • Assist with equipment assembly, disassembly, cleaning, routine maintenance, and general laboratory upkeep.
  • Perform Clean-In-Place (CIP) and Steam-In-Place (SIP) activities as required.
  • Support laboratory safety, quality, and compliance initiatives while maintaining an organized and safe work environment.
  • Assist with inventory management, material organization, vendor oversight, and other routine laboratory activities.
  • Analyze experimental data, troubleshoot routine process issues, and collaborate with team members to support successful execution of laboratory activities.
  • Follow established procedures, safety requirements, and quality standards while working in a collaborative team environment.

Qualifications:
  • Bachelor's degree in Engineering, Science, or a related technical field, OR
  • Associate degree with 1+ year of laboratory or manufacturing experience, OR
  • 2+ years of relevant laboratory or manufacturing experience.

This job description is a complete list of all desired skills, but not all are required. We strongly encourage candidates who have some of the skills to apply. We look forward to a conversation to learn more about you!
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