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Downstream Process Development Jobs in Ontario (NOW HIRING)

CA$150K - CA$180K/yr

... the development cycle, moving away from siloed, downstream testing toward a model of shared ... If you would like more information about how your data is processed, please contact us. apply for ...

Serve as a subject matter expert for system testing, including development of test plans for new ... Ability to understand and articulate how system changes impact downstream data, reporting and ...

Regional Account Manager Ottawa, ON

Ottawa, ON ยท Remote

CA$71K - CA$87K/yr

... development centers globally. Powered by a dynamic workforce, we're united by our purpose of ... The RAM has the responsibility of owning downstream contractor demand for all James Hardie products ...

Regional Account Manager Ottawa, ON

Ottawa, ON ยท Remote

CA$71K - CA$87K/yr

... development centers globally. Powered by a dynamic workforce, we're united by our purpose of ... The RAM has the responsibility of owning downstream contractor demand for all James Hardie products ...

Backend Engineer

Toronto, ON ยท Remote

CA$140K - CA$240K/yr

This role contributes to the development and evolution of core backend and distributed systems ... In parallel, this individual will help enable downstream product capabilities, operational ...

Improve event listener and re-processing flows (throttling, backpressure, rate-limit handling) to ... Integrate data services with upstream and downstream systems (CRM systems, data lakes/warehouses ...

Showing results 41-60

Downstream Process Development information

What is downstream process development?

A Downstream Process Development job involves optimizing and scaling purification processes for biologics, such as proteins, antibodies, or gene therapies. Scientists and engineers in this role develop efficient methods for isolation, purification, and formulation of therapeutic products while ensuring quality and regulatory compliance. Key activities include chromatography, filtration, and process analytics to improve yield, purity, and consistency. This role is critical in biotech and pharmaceutical industries to ensure safe and effective drug production for clinical and commercial use.

What does someone in downstream process development do?

Professionals in Downstream Process Development are typically responsible for designing, optimizing, and scaling up purification processes for biopharmaceutical products. Their day-to-day work may involve conducting laboratory experiments, analyzing data, troubleshooting technical issues, and documenting process changes in accordance with regulatory standards. They also frequently collaborate with upstream processing, analytical, and quality teams to ensure seamless transfer and integration of processes. The role often includes participating in project meetings, contributing to process validation efforts, and supporting technology transfer to manufacturing teams, making it both technically challenging and collaborative.

What are the key skills and qualifications needed for downstream process development?

To excel in Downstream Process Development, you generally need a strong background in biochemistry, chemical engineering, or a related life sciences field, often with experience in bioprocessing or purification technologies. Familiarity with chromatography systems, filtration equipment, process analytical technology (PAT), and relevant software such as DeltaV or Unicorn is frequently required, along with knowledge of GMP and regulatory standards. Excellent problem-solving, project management, and cross-functional communication skills help professionals succeed in dynamic team environments. These competencies are crucial for developing efficient, scalable purification processes that ensure high product quality and support organizational goals.

Infographic showing various Downstream Process Development job openings in Ontario as of September 2026, with employment types broken down into 1% Internship, 1% As Needed, 81% Full Time, 15% Part Time, and 2% Contract. Highlights an 86% Physical, 3% Hybrid, and 11% Remote job distribution.

Water Microbiology Technician - Research Assistant Technician II

Guelph, ON โ€ข On-site

Full-time

Posted 26 days ago


Job description

Department:ย Environmental Sciencesย 
This position is classified under the Grant and Trust Administrative & Technical Group

Temporary full-time from 09/14/2026 to 09/13/2027

If you are a current employee of the University of Guelph you must apply on the internal Career Page in order to be considered as an internal applicant.

Career Opportunities (sapsf.com)

General Purpose

Our research team is dedicated to the Surveillance and Control of Pathogens and Antimicrobial Resistance (AMR) in the Environment,ย predominately focusing on how to monitor and model the risks that waterborne pathogens and other pollutants pose to human health. The research program is led by the Canada Excellence in Research Chair (CERC) in Waterborne Pathogens: Surveillance, Prediction and Mitigation. Our primary areas of research are smart sampling systems, lab-based pathogen and AMR detection, novel low-cost water quality sensor development, source tracking, modelling and risk estimation, and novel green infrastructure-based pathogen treatment systems. We are seeking a highly motivated and experienced Water Microbiologist to join our team.

General outline of duties: This position will play a key role in lab-based pathogen and AMR detection. They will be required to establish, optimize and perform lab-based pathogen and AMR detection on a regular basis using culture-based and molecular methods; they will be responsible for the proper tracking, documentation, storage, and processing of water samples based on establish procedures; they will participate in field research, including the execution of water sampling and sensing campaigns; they will be responsible for data collection, screening and quality control; they will be involved in the general support of research activities for a growing and dynamic interdisciplinary research team.

Our research environment is highly collaborative. Candidates who bring a positive and team-focused attitude, who are self-motivated, and enjoy working within a fast-paced environment, will be most successful in this role.

Duties and Responsibilities

  • Collaborate with the Principal Investigator, students and staff to meet research program milestones. For more information on ongoing projects in the program see microscape.ca.
  • Develop, validate, and execute new or optimized methods, and prepare associated research documentation, including but not limited to lab protocols, field data collection forms, SOPs, and records.
  • Independently perform routine water sampling and analysis following standardized guidelines and procedures, including recording and/or coding data requiring some judgement/interpretation.
  • Communicate technical information accurately and effectively in oral, written, visual and electronic forms. The applicant will be expected to serve as a source of information on standard research techniques, train others in technical procedures or operations, and provide guidance to students on use of equipment or standard research techniques for their research projects.
  • Operate, maintain and troubleshoot problems with basic lab equipment.
  • Supports data management, performs preliminary analysis when appropriate; recognize obvious deviations in research results and flag for senior researchers to address.
  • Support the knowledge translation and transfer of research outcomes to project stakeholders. This may include contributing to project reports, manuscripts, grant proposals and other research presentations.
  • Organize laboratory and stock, maintains inventory, replenishing supplies as required. This includes the preparation of media, buffer, reagents, solutions, cultures and related material according to specifications for routine laboratory use.
  • Contribute to the technical proficiency of the team through acquisition of knowledge and abilities related to tools, technologies, software, and systems relevant to the research program.

Requirements

  • 2-3 years of post-secondary education, with some experience required. This may include Bachelor of Science or College Diploma in Microbiology, Environmental Science, Environmental Microbiology, Water Sciences, Water Quality, Water Science, Environmental Technology, or a related program. Experience should be directly related to water microbiology in a laboratory setting.
  • Knowledge of and experience with Biosafety Level 2 (BSL-2) pathogens.
  • Demonstrated experience in setting up, testing, optimizing and validating a variety of culture-based microbiology techniques for environmental isolates including; aseptic culture, aerobic and anaerobic culture, strain isolation, cryopreservation and maintenance of biobanks.
  • Demonstrated experience in setting up, testing, optimizing and validating a variety of molecular microbiology techniques including; DNA extraction, qPCR, primer design and validation.
  • Demonstrated ability to track and maintain sample chain of custody, from receipt through downstream processing.
  • Strong understanding of scientific principles, data management and quality control.
  • Proven ability to work independently and collaboratively within a team.
  • Demonstrated attention to detail, effective time management, and strong organizational skills that include setting priorities, and meeting deadlines.
  • Valid Driver's License as travel to field sites may be required.

Working Environmentย 

  • This position involves laboratory work and outdoor fieldwork. Field activities take place at creek and river sites, urban stormwater sites, and agricultural settings around the City of Guelph and surrounding area, often in variable weather conditions. The position requires the ability to safely access field sites including creek banks and stormwater infrastructure. Travel to field sites (ranging from 5- 300km) will be required. Hybrid or remote work arrangements are not suitable to this position.

Preferred experience

  • Demonstrated experience with specialized laboratory techniques or instruments would be considered an asset, including: IDEXX assays (e.g. Colilert), multiplex PCR assays (e.g. TaqArray), KingFisher instruments, 3D printers, and/or Nanopore Sequencers (e.g. GridION).
  • Demonstrated field work experience in water sampling and assessment including grab sampling and on-site measurement of water quality indicators (pH, DO, temperature, EC, salinity, etc.) would be considered an asset.
  • Demonstrated experience with advanced field sampling and monitoring techniques and equipment would be considered an asset; including passive sampling, ultrafiltration, operation of autosamplers, and/or installation and maintenance of water sensors.
  • Experience in a research environment (academic or industry) would be considered an asset.
  • Expertise in any of the following areas is considered an asset: water policy, water resources, watershed management, hydrology, water chemistry, freshwater ecology, remote sensing, water quality data management and analysis.

In your cover letter, please specify the source where you found this job posting.

Employee Type: Temporaryย ย 
Classification: Grant/ Trust fund position, Band ย GTAT - Band B

GTAT (Grant & Trust Administrative and Technical) Salary Gridย 

At the University of Guelph, fostering aย culture of inclusion is an institutional imperative. The University invites and encourages applications from all qualified individuals, including from groups that are traditionally underrepresented in employment, who may contribute to further diversification of our Institution.

Posting Date:ย 08/14/2026ย 
Close Date:ย 09/06/2026