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Downstream Process Development Jobs in Ontario (NOW HIRING)

... development prospects. Because we believe that your career path should be as unique as you are ... Engage downstream internal customers to understand their requirements and translate feedback into ...

... downstream operations Develop and execute transfer strategies, project plans, risk assessments, and readiness activities to support successful process implementation Partner with process development ...

Engage Business Readiness teams to ensure process artefacts support downstream operational ... Experience within anenvironment of continuous improvement and capability development. * Confident ...

Technical expertise in biologics drug substance upstream and downstream operations, analytical testing, process development, and tech transfer. Ability to work independently and as part of a team in ...

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Downstream Process Development information

What is downstream process development?

A Downstream Process Development job involves optimizing and scaling purification processes for biologics, such as proteins, antibodies, or gene therapies. Scientists and engineers in this role develop efficient methods for isolation, purification, and formulation of therapeutic products while ensuring quality and regulatory compliance. Key activities include chromatography, filtration, and process analytics to improve yield, purity, and consistency. This role is critical in biotech and pharmaceutical industries to ensure safe and effective drug production for clinical and commercial use.

What does someone in downstream process development do?

Professionals in Downstream Process Development are typically responsible for designing, optimizing, and scaling up purification processes for biopharmaceutical products. Their day-to-day work may involve conducting laboratory experiments, analyzing data, troubleshooting technical issues, and documenting process changes in accordance with regulatory standards. They also frequently collaborate with upstream processing, analytical, and quality teams to ensure seamless transfer and integration of processes. The role often includes participating in project meetings, contributing to process validation efforts, and supporting technology transfer to manufacturing teams, making it both technically challenging and collaborative.

What are the key skills and qualifications needed for downstream process development?

To excel in Downstream Process Development, you generally need a strong background in biochemistry, chemical engineering, or a related life sciences field, often with experience in bioprocessing or purification technologies. Familiarity with chromatography systems, filtration equipment, process analytical technology (PAT), and relevant software such as DeltaV or Unicorn is frequently required, along with knowledge of GMP and regulatory standards. Excellent problem-solving, project management, and cross-functional communication skills help professionals succeed in dynamic team environments. These competencies are crucial for developing efficient, scalable purification processes that ensure high product quality and support organizational goals.

Infographic showing various Downstream Process Development job openings in Ontario as of September 2026, with employment types broken down into 1% Internship, 1% As Needed, 81% Full Time, 15% Part Time, and 2% Contract. Highlights an 86% Physical, 3% Hybrid, and 11% Remote job distribution.

Process Development Scientist Canada (Toronto)

Oakville, ON โ€ข On-site

CA$71K - CA$107K/yr

Full-time

Medical, Dental, Vision, Life, Retirement, PTO

Posted 13 days ago


Job description

Work Your Magic with us!Start your next chapter and join MilliporeSigma.

Ready to explore, break barriers, and discover more? We know you've got big plans - so do we! Our colleagues across the globe love innovating with science and technology to enrich people's lives with our solutions in Healthcare, Life Science, and Electronics. Together, we dream big and are passionate about caring for our rich mix of people, customers, patients, and planet. That's why we are always looking for curious minds that see themselves imagining the unimaginable with us.

This role does not offer sponsorship for work authorization. External applicants must be eligible to work in the US.


Your Role:
MilliporeSigma is looking for a Process Development Scientist to join the Technical and Scientific Solutions team in or near the Toronto, ON area in Canada. The Process Development Scientist position is part of a worldwide team of engineers and scientists reporting into the technical support group for MilliporeSigma's Process Solutions business. Specific responsibilities include:

  • Proactively pursuing and performing downstream process development studies for the purification of therapeutic proteins using MilliporeSigma technologies such as sterile, depth, tangential flow and virus filtration and chromatography.
  • Involvement in filter selection and sizing, process optimization, and technology transfer activities associated with the downstream purification of new pharmaceuticals
  • Provide consultation to customers through email or teleconference calls.
  • Collaborate and work with customer process development groups in Canada.
  • Work collaboratively with a team of local MilliporeSigma account managers to provide technical expertise to local customers.
  • Adequately document customer interfacing activities.
  • Communicate and work effectively in cross-functional teams, influence technical approaches, and support strategy execution.
  • 20% domestic Canada travel

Who You Are

Minimum Qualifications:

  • Bachelor's Degree in Chemical Engineering, Biochemistry, or other life science discipline.
  • 5+ years of experience in pharmaceutical development or technology implementation.

Preferred Qualifications:

  • Master's Degree in engineering or scientific discipline.
  • Sound understanding of upstream and/or downstream biomanufacturing process requirements, best practices, and industry standards.
  • Ability to identify thought leadership opportunities and execute through lunch & learns, publications, presentations, etc. with a focus on customer collaboration.
  • Ability to cope with change, shift gears quickly, and comfortably handle risk and uncertainty.
  • Ability to build effective relationships; both internally and externally.
  • Highly motivated, self-directed, and able to work independently in a field-based position.
  • Demonstrated ability to communicate clearly, concisely, and effectively to diverse audiences through both written and oral communications
  • Ability to produce quality written experimental reports and other appropriate documentation.
  • Exceptional hands-on laboratory, analytical, and technology skills.

Pay range for this position: $71,600 - $107,500

Our ranges incorporate all levels and career types available within this specific role and are derived from relevant industry market data within Canada. Should we decide to make an offer, we will consider several factors, including but not limited to your skills, experience, career level, and other job-related factors. This role may offer the following benefits: health, vision, and dental coverage; life insurance; disability; a Defined Contribution Pension Plan program; paid time off; and paid holidays; among other employee benefits. This role may also be eligible for short-term or long-term incentive compensation, including, but not limited to, cash bonuses.We use AI in the process of screening, assessing and/or selecting applicants. Further details onhow we use AI in our recruitment process can be foundhere.


What we offer: We are curious minds that come from a broad range of backgrounds, perspectives, and life experiences. We believe that this variety drives excellence and innovation, strengthening our ability to lead in science and technology. We are committed to creating access and opportunities for all to develop and grow at your own pace. Join us in building a culture of inclusion and belonging that impacts millions and empowers everyone to work their magic and champion human progress!

Apply now and become a part of a team that is dedicated to Sparking Discovery and Elevating Humanity!

Employment Type: FULL_TIME