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How much do dmpk jobs pay per year?

As of Aug 22, 2026, the average yearly pay for dmpk in Indiana is $182,053.00, according to ZipRecruiter salary data. Most workers in this role earn between $128,900.00 and $217,900.00 per year, depending on experience, location, and employer.

What is a DMPK?

A DMPK (Drug Metabolism and Pharmacokinetics) job involves studying how drugs are absorbed, distributed, metabolized, and excreted in the body. Professionals in this field assess drug interactions, optimize dosing strategies, and predict potential toxicity. They work closely with medicinal chemists, pharmacologists, and toxicologists to support drug discovery and development. DMPK scientists use analytical techniques such as mass spectrometry and in vitro/in vivo models to evaluate pharmacokinetic properties. Their work helps ensure the safety and efficacy of new therapeutics before clinical trials.

What are the key skills and qualifications needed to thrive in the DMPK position?

To succeed in a DMPK (Drug Metabolism and Pharmacokinetics) role, you generally need advanced knowledge in pharmacology, biochemistry, and analytical chemistry, supported by a relevant advanced degree such as an MSc or PhD. Familiarity and hands-on experience with LC-MS/MS instrumentation, pharmacokinetic modeling software (such as Phoenix WinNonlin), and regulatory guidelines are highly valuable. Strong critical thinking, communication, and organizational skills help distinguish candidates, especially when interpreting data and collaborating with multidisciplinary teams. Mastery of these skills is essential for ensuring effective evaluation of drug candidates and clear communication of findings in a fast-paced research environment.

What are some typical challenges faced in a DMPK position and how are they addressed?

Professionals in DMPK roles often encounter the challenge of interpreting complex pharmacokinetic and metabolism data under tight project timelines. Coordinating data from various sources, troubleshooting analytical equipment, and keeping pace with evolving regulatory standards can demand adaptability and proactive problem-solving. Effective DMPK scientists collaborate closely with medicinal chemists, toxicologists, and clinical teams to ensure integrated drug development efforts. Many teams also have robust mentorship and training in place to help new hires navigate technical hurdles and develop their expertise. Overcoming these challenges requires a combination of technical rigor, teamwork, and ongoing professional development.

What are the most commonly searched types of Dmpk jobs in Indiana?

The most popular types of Dmpk jobs in Indiana are:

What are popular job titles related to Dmpk jobs in Indiana?

For Dmpk jobs in Indiana, the most frequently searched job titles are:

What job categories do people searching Dmpk jobs in Indiana look for?

The top searched job categories for Dmpk jobs in Indiana are:

Dmpk jobs near you
Infographic showing various Dmpk job openings in Indiana as of August 2026, with employment types broken down into 98% Full Time, and 2% Contract. Highlights an 87% Physical, 7% Hybrid, and 6% Remote job distribution, with an average salary of $182,053 per year, or $87.5 per hour.

Principal Research Scientist - Medicinal Chemist

Elanco Animal Health Incorporated

Indianapolis, IN • On-site

Full-time

Retirement, PTO

Re-posted 17 hours ago

Elanco rating

7.8

Company rating: 7.8 out of 10

Based on 25 frontline employees who took The Breakroom Quiz

50th of 86 rated pharmaceutical

Job description

At Elanco (NYSE: ELAN) - it all starts with animals!
As a global leader in animal health, we are dedicated to innovation and delivering products and services to prevent and treat disease in farm animals and pets. At Elanco, we are driven by our vision of Food and Companionship Enriching Life and our purpose - all to Go Beyond for Animals, Customers, Society and Our People.
At Elanco, we pride ourselves on fostering a diverse and inclusive work environment. We believe that diversity is the driving force behind innovation, creativity, and overall business success. Here, you'll be part of a company that values and champions new ways of thinking, work with dynamic individuals, and acquire new skills and experiences that will propel your career to new heights.
Making animals' lives better makes life better - join our team today!
Your Role:
Principal Research Scientist - Medicinal Chemist
As a Principal Research Scientist in Medicinal Chemistry, you will be a key figure in our small molecule drug discovery engine, guiding the design and synthesis of innovative medicines that improve the health and well-being of animals. You will apply your scientific expertise to advance multiple therapeutic programs, from lead generation to development candidate selection. Partnering with a global, cross-functional team of scientists, you will leverage cutting-edge technologies like AI/ML and DNA-Encoded Libraries to solve complex chemical challenges. This is an exciting opportunity to make a significant impact on our discovery portfolio and help shape the future of our growing research team in Indianapolis.
Your Responsibilities:
  • Guide the design and optimization of novel small molecules by applying advanced synthetic strategies and integrating biological, pharmacological, and ADME/PK data to manage Structure-Activity Relationship (SAR) campaigns.

  • Serve as a key medicinal chemistry figure on multidisciplinary project teams, collaborating with partners in Biology, Pharmacology, DMPK, Toxicology, and Computational Sciences to strategically advance discovery programs.

  • Manage and coordinate synthetic chemistry efforts with external Contract Research Organizations (CROs) and internal partners, ensuring the efficient execution of project goals and timelines.

  • Leverage cutting-edge drug discovery technologies, including DNA-Encoded Libraries (DEL), computational chemistry, and AI/ML-enabled tools, to accelerate hit identification and lead optimization.

  • Promote scientific excellence and data integrity while providing mentorship and technical guidance to junior scientists, fostering a culture of innovation and collaboration.

What You Need to Succeed (minimum qualifications):
  • Education: PhD in Medicinal Chemistry, Organic Chemistry, or a related scientific discipline.

  • Experience: A minimum of 6 years of relevant industry experience in medicinal chemistry within a pharmaceutical, biotechnology, or animal health research environment.

  • Top Skills: Demonstrated expertise in modern medicinal chemistry, including the design and multi-step synthesis of complex small molecules, and a strong understanding of Structure-Activity Relationships (SAR), pharmacology, and ADME/PK principles. Proven ability to autonomously manage scientific initiatives within a cross-functional team and manage external collaborations with CROs.

What will give you a strong candidate profile (preferred qualifications):
  • Postdoctoral experience.

  • Experience applying modern drug discovery technologies such as DNA-Encoded Libraries (DEL), computational chemistry, or AI/ML-enabled molecular design.

  • A strong track record of advancing small-molecule discovery programs toward preclinical development, evidenced by significant patent and/or publication contributions.

  • Prior research experience in the animal health industry.

  • Expertise in peptide chemistry, macrocycles, or related drug modalities.

Additional Information:
  • Travel: Less than 10%

  • Location: Global Elanco Headquarters - Indianapolis, IN - Hybrid Work Environment

Don't meet every single requirement? Studies have shown underrecognized groups are less likely to apply to jobs unless they meet every single qualification. At Elanco we are dedicated to building a diverse and inclusive work environment. If you think you might be a good fit for a role but don't necessarily meet every requirement, we encourage you to apply. You may be the right candidate for this role or other roles!
Elanco Benefits and Perks:
We offer a comprehensive benefits package focusing on financial, physical, and mental well-being while encouraging our employees to pursue our purpose! Some highlights include:
  • Multiple relocation packages

  • Two weeklong shutdowns (mid-summer and year-end) in the US (in addition to PTO)

  • 8-week parental leave

  • 9 Employee Resource Groups

  • Annual bonus offering

  • Flexible work arrangements

  • Up to 6% 401K matching

Elanco is an EEO/Affirmative Action Employer and does not discriminate on the basis of age, race, color, religion, gender, sexual orientation, gender identity, gender expression, national origin, protected veteran status, disability or any other legally protected status
Elanco may use automated tools, including AI, to support parts of our recruitment process, such as reviewing applications against job-related criteria and/or transferrable skills. These tools help ensure a consistent, structured evaluation, but they do not make hiring decisions. All decisions involve a human reviewer. For more information on how we handle personal data, please see our Elanco Workforce Privacy Notice.

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