Discovery Biology Jobs (NOW HIRING)

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Job Description
We are seeking a highly motivated Scientist, Biology to support pharmacokinetic (PK) bioanalysis for large molecules and antibody-drug conjugates (ADCs) across discovery and early development programs. This hands-on, laboratory-based role will be responsible for developing, implementing, and executing high-throughput bioanalytical methods that generate high-quality, decision-enabling data for research and development teams.
The successful candidate will work closely with cross-functional partners and contribute to advancing biologics and ADC programs through innovative bioanalytical solutions. This role is ideal for a scientifically driven individual who thrives in a fast-paced environment, demonstrates strong ownership and leadership, and is excited to expand their impact beyond bioanalysis into broader drug discovery initiatives.
Key Responsibilities

• Lead the development, optimization, validation, and implementation of high-throughput bioanalytical methods supporting preclinical pharmacokinetic studies for biologics and ADCs.
• Design, develop, and execute bioanalytical assays using ligand-binding, immunochemical, and mass spectrometry-based platforms, incorporating laboratory automation where appropriate.
• Analyze, interpret, and communicate bioanalytical and pharmacokinetic data using industry-standard software and analytical approaches.
• Operate, troubleshoot, and maintain analytical instrumentation, including LC-MS/MS systems and ligand-binding assay platforms.
• Prepare and present scientific reports, technical documentation, and study summaries to internal stakeholders.
• Partner effectively with cross-functional teams including Discovery Biology, DMPK, Bioanalytical Sciences, and Translational Research.
• Identify opportunities to improve workflows, enhance assay performance, and expand bioanalytical capabilities through innovative approaches and technologies.
• Contribute to broader discovery and development efforts by applying scientific expertise to complex biological questions.

Basic Qualifications

• Bachelor's degree and 6+ years of relevant experience, OR
• Master's degree and 4+ years of relevant experience, OR
• PhD or PharmD with relevant scientific training

Preferred Qualifications

• Degree in Pharmaceutical Sciences, Biochemistry, Biology, Chemistry, or a related scientific discipline.
• 2-5 years of hands-on industry experience in bioanalysis, pharmacokinetics, or related areas.
• Strong expertise in ligand-binding assays and bioanalytical methodologies for biologics and ADCs.
• Hands-on experience with immunoprecipitation, enzymatic digestion, LC-MS/MS, MSD platforms, and other ligand-binding assay technologies.
• Demonstrated experience processing biological samples and quantifying biologics, small molecules, ADCs, payloads, and metabolites, including biotransformation assessments.
• Proficiency in pharmacokinetic data analysis software, including Phoenix WinNonlin or comparable tools.
• Experience developing, standardizing, and implementing bioanalytical methods in a regulated research environment.
• Experience with laboratory automation and high-throughput screening platforms.
• Familiarity with in vitro assay development and screening technologies.
• Working knowledge of HTS workflows using 96-, 384-, and 1536-well assay formats.
• Excellent organizational skills with the ability to manage multiple priorities independently while maintaining high-quality scientific output.

The salary range for this position is: $146,540.00 - $189,640.00. Gilead considers a variety of factors when determining base compensation, including experience, qualifications, and geographic location. These considerations mean actual compensation will vary. This position may also be eligible for a discretionary annual bonus, discretionary stock-based long-term incentives (eligibility may vary based on role), paid time off, and a benefits package. Benefits include company-sponsored medical, dental, vision, and life insurance plans*.
For additional benefits information, visit:
https://www.gilead.com/careers/compensation-benefits-and-wellbeing
* Eligible employees may participate in benefit plans, subject to the terms and conditions of the applicable plans.
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