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Director Statistical Programming Jobs in Chicago, IL

cap

Senior SAS Programmer

Winnetka, IL · Remote

$87K - $111K/yr

The validity of statistical programming used in assigned projects. * Provide timely and accurate ... Other assignments as directed by the Manager. Knowledge / Skills Required / Preferred Personal:

Tempus

Director, Biostatistics

Chicago, IL

$190K - $260K/yr

The Director of Biostatistics builds and maintains strong collaborations with other teams across ... Experience working with other groups involved in clinical research, such as Statistical Programmers ...

Tempus

Director, Biostatistics

Chicago, IL · On-site

$190K - $260K/yr

The Director of Biostatistics builds and maintains strong collaborations with other teams across ... Experience working with other groups involved in clinical research, such as Statistical Programmers ...

The Salvation Army

Youth Development Director

Norridge, IL

$58.66K - $70.39K/yr

... statistics, finances, communications, and evaluation for all Corps youth programs. (Finances ... Evaluate all youth programming and visioning as it relates to Corps review. * Coordinate with staff ...

TransUnion

Lead Data Scientist

Chicago, IL · On-site

$100K - $160K/yr

... Director of Data Science & Analytics. The Financial Services Analytics team is an industry ... Advanced programming skills; mastery of a statistical language such as R or SAS; experience using ...

TransUnion

Lead Data Scientist

Chicago, IL

$100K - $160K/yr

... Director of Data Science & Analytics. The Financial Services Analytics team is an industry ... Advanced programming skills; mastery of a statistical language such as R or SAS; experience using ...

Transunion

Lead Data Scientist

Chicago, IL

$100K - $160K/yr

... Director of Data Science & Analytics. The Financial Services Analytics team is an industry ... Advanced programming skills; mastery of a statistical language such as R or SAS; experience using ...

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Director Statistical Programming information

See Chicago, IL salary details

$158.1K

$288.6K

$354.4K

How much do director statistical programming jobs pay per year?

As of May 29, 2026, the average yearly pay for director statistical programming in Chicago, IL is $288,592.00, according to ZipRecruiter salary data. Most workers in this role earn between $268,400.00 and $332,200.00 per year, depending on experience, location, and employer.

What Is the Job of a Director Statistical Programming?

The job of a director of statistical programming oversees the development and implementation of SAS programs to produce statistical analysis datasets. In this career, your responsibilities include managing the team that generates tables and graphs using the SAS programs for applications such as clinical studies. Other duties include participating in the planning and review of statistical analysis and studying reports, abstracts, and manuscripts as required. You collaborate with project leads to contribute to department operations and standards, such as CDISC for clinical research.

What are the key skills and qualifications needed to thrive as a Director of Statistical Programming, and why are they important?

To thrive as a Director of Statistical Programming, you need advanced expertise in statistical analysis, programming languages such as SAS or R, and a strong background in clinical trial data, typically supported by a degree in statistics, mathematics, or a related field. Familiarity with regulatory submission processes, CDISC standards, and project management tools is essential, as are relevant certifications like SAS Certified Professional. Leadership, effective communication, and strategic thinking are key soft skills for managing teams and collaborating across departments. These skills ensure high-quality data outputs, regulatory compliance, and successful execution of complex clinical development projects.

How does a Director of Statistical Programming typically collaborate with cross-functional teams in a pharmaceutical or biotech company?

A Director of Statistical Programming regularly works with biostatistics, clinical data management, regulatory affairs, and medical writing teams to ensure that statistical deliverables meet project timelines and regulatory requirements. They coordinate programming efforts across multiple studies, provide leadership and mentorship to programming staff, and help resolve technical or resource-related challenges. Effective collaboration is essential to streamline workflows, maintain data integrity, and ensure clear communication of statistical results within the organization.

What does a Director of Statistical Programming do?

A Director of Statistical Programming oversees teams responsible for the programming and analysis of clinical trial data, ensuring the accuracy and integrity of statistical outputs. They set departmental strategies, manage resources, and ensure compliance with regulatory requirements and industry standards. This role also involves collaborating with other departments, such as biostatistics and clinical operations, to support the successful delivery of statistical analyses for drug development and regulatory submissions. They play a key leadership role in mentoring staff and advancing programming processes and technologies.
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Director Statistical Programming jobs near you
Infographic showing various Director Statistical Programming job openings in Chicago, IL as of May 2026, with employment types broken down into 7% As Needed, 80% Full Time, 10% Part Time, 2% Contract, and 1% Summer. Highlights an 78% Physical, 6% Hybrid, and 16% Remote job distribution, with an average salary of $288,592 per year, or $138.7 per hour.

Team Lead, Statistical Programming, Oncology (Director)

Astellas Pharma, Inc.

Northbrook, IL • On-site

Full-time

Medical, Dental, Vision, Life, Retirement, PTO

Posted 16 days ago

Job description

About Astellas
Astellas is a global life sciences company committed to turning innovative science into VALUE for patients. We provide transformative therapies in disease areas that include oncology, ophthalmology, urology, immunology and women's health. Through our research and development programs, we are pioneering new healthcare solutions for diseases with high unmet medical need. Learn more at Astellas.com.
Are you driven to make a real difference in the lives of patients?
We're seeking passionate individuals who thrive in dynamic environments, embrace new ideas, and aren't afraid to take intelligent risks. People who act with unwavering integrity and are deeply committed to making a tangible impact.
Purpose & Scope
As a senior statistician, data scientist or clinical programmer, the position has a dual purpose: manage 4+ direct reports and have a major influence on the leadership and technical capabilities of the department.
The position can act as Global Statistical lead (GSTATL), Global Programmer Lead (GPROGL), Real World Data Scientist lead (RWDSL), Lead Product Statistician (LPS), Statistical Biomarker Lead (SBL) or as a Regional/site Head.
With no or minimal experience as people manager and an extensive knowledge of the scientific and regulatory area of responsibility and experience in multiple indications; the position is expected to ask critical scientific questions, challenge hypotheses, designs and results interpretation.
The position is responsible for the optimal development and assignments of reports (all individual contributors; Statistical Science Lead, Statistician, Statistical programming Lead, Programmer and RWD scientist) to Astellas asset teams, study teams or deliverables teams (e.g. IEGP, EDAP) for the assigned projects.
The position supports Senior management with decision making at the asset and portfolio level with an impact within and outside of the organization. The position works independently and involves the right level of participants as needed effectively engaged as a matrix team member in M&D.
This position represents Astellas on statistical matters related to clinical data, RWD, Biomarkers PROs, PK/PD analysis or methodology at meetings with regulatory authorities, key opinion leaders and HTAs
Role and Responsibilities
The position is accountable for multiple projects, challenging and assessing the asset strategy and ensuring the statistical/scientific soundness of all input and deliverables for the assigned projects. The position works on the most complex and critical projects from pre-Candidate Nomination (CN) till life cycle management impacting CN, Proof of Concept, approval and post submission strategies.
  • Advises asset teams on challenging statistical/epidemiological design, analysis and decision-making issues for interventional and non-interventional studies.
  • How RWD and Clinical Trial post hoc analyses can support drug development, Pricing submissions and the Growth strategy in general.
  • How omics and biomarkers can support drug development and the BOLD objectives
  • How programming support will be executed for all stakeholders' needs globally. Performs/supervises modeling and simulations, leverages external experts to provide input to clinical development issues.
  • Provides oversight on statistical/scientific/programming matters for meetings with regulatory authorities, HTAs, key opinion leaders and similar experts
  • Reviews key project level documents
  • Participates in due diligence activities, external initiatives or working groups.
  • Presents and defends complex solutions to governance committees (KACHI, PRC, MA-C, EC), key stakeholders, or regulatory bodies in a compelling and impactful way
  • Stays at the cutting edge of methodology development in statistics, epidemiology, regulatory and HTA guidelines, and industry trends in drug development, particularly with respect to the Primary Focus of interest, and signals relevant developments in a timely manner for the company.
  • Ensures efficient and innovative ways of programming are selected for each deliverable
  • Researches, creates, validates, implements and teaches complex methodologies ensuring the department stays at the forefront of innovational drug development

People Management
  • Supervision (first line manager) of 4+ direct reports
  • Assist with recruitment, development / career management and retention of staff
  • Oversees adherence to timelines, standards, processes for work assigned to their members of staff
  • Responsible for compliance of direct reports with Astellas policies and procedures

Personal development / Collaboration
  • Challenges and influences peers and senior managers inside and outside of Quantitative Sciences and Evidence Generation (QSEG) on best practice in their area of competence
  • As a leader, member of external industry or professional organizations, develops and maintains relationships with peers and key leaders. Actively participates in professional association activities to support the branding of Astellas
  • Understands Astellas' priorities, uses position to advance Astellas' mission through high quality statistical programming work - ensures programming team stays current with changes in regulatory requirements globally
  • Contributes in ensuring that Astellas is at the forefront of recruitment, training, professional development and retention of statistical programming personnel.
  • Partners with SRS LT to set short- and long-term strategic direction for programming function.
  • Partners with programming team in other Astellas sites to ensure global consistency, global efficient resource utilization and development.

Required Qualifications
  • Bachelor's or master's in statistics, mathematics, or related field
  • 12+ years (15+ years for Bachelor) of experience of relevant programming experience in the pharmaceutical industry and working with vendors
  • 8+ years' experience as a lead programmer working on global clinical studies and projects or global process and system initiatives
  • 5+ years' experience in mentoring/leading statistical programmers
  • Prior working experience with Oncology
  • Prior experiencing leading a team

Location and Working Environment
This position is based in Northbrook, Illinois. Remote work from anywhere in the US is available.
At Astellas we recognize the importance of work/life balance, and we are proud to offer a hybrid working solution allowing time to connect with colleagues at the office with the flexibility to also work from home. We believe this will optimize the most productive work environment for all employees to succeed and deliver. Hybrid work from certain locations may be permitted in accordance with Astellas' Responsible Flexibility Guidelines.
What awaits you at Astellas?
  • Global collaboration: Become part of a connected global business of like-minded life science leaders, all dedicated to improving patients' lives worldwide.
  • Real-world patient impact: Contribute to transformative therapies that reach patients around the world, knowing your work makes a difference every day.
  • Relentless Innovation: Join a company at the forefront of scientific breakthroughs, where you'll have the opportunity to shape the future of healthcare.
  • A Culture of Growth: Chart your own course within a supportive environment that values your contributions, champions your development, and empowers you to pursue your passions.

Our Organizational Values and Behaviors
Values: Innovation, Integrity and Impact sit at the heart of what we do.
Behaviors: We come together as 'One Astellas', working with courage and a sense of urgency. We are outcome focused and consistently take accountability for our personal contribution.
Salary Range
$170,450 - $243,500 (Final compensation will be determined based on a variety of factors, including but not limited to skills, experience and organizational equity considerations)
Benefits:
  • Medical, Dental and Vision Insurance
  • Generous Paid Time Off options, including Vacation and Sick time, plus national holidays including year-end shut down
  • 401(k) match and annual company contribution
  • Company paid life insurance
  • Annual Corporate Bonus and Quarterly Sales Incentive for eligible positions
  • Long Term Incentive Plan for eligible positions
  • Company fleet vehicle for eligible positions
  • Referral bonus program

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