About the role, the Director, Operational Excellence (OE) leads the network-wide OE agenda for AstraZeneca's autologous Cell Therapy. You will establish basic conditions and eliminate waste across ...
About the role, the Director, Operational Excellence (OE) leads the network-wide OE agenda for AstraZeneca's autologous Cell Therapy. You will establish basic conditions and eliminate waste across ...
About the role, the Director, Operational Excellence (OE) leads the network-wide OE agenda for AstraZeneca's autologous Cell Therapy. You will establish basic conditions and eliminate waste across ...
About the role, the Director, Operational Excellence (OE) leads the network-wide OE agenda for AstraZeneca's autologous Cell Therapy. You will establish basic conditions and eliminate waste across ...
Director, Operational Excellence- Cell Therapy Manufacturing
Rockville, MD · On-site
$148 - $222K/hr
About the role, the Director, Operational Excellence (OE) leads the network-wide OE agenda for AstraZeneca's autologous Cell Therapy. You will establish basic conditions and eliminate waste across ...
Director, Operational Excellence- Cell Therapy Manufacturing
Rockville, MD · On-site
$148 - $222K/hr
About the role, the Director, Operational Excellence (OE) leads the network-wide OE agenda for AstraZeneca's autologous Cell Therapy. You will establish basic conditions and eliminate waste across ...
We are seeking an Operational Excellence Director to lead the optimization of workflows and play a key role in the continuous improvement across all projects and operations. This role ensures ...
We are seeking an Operational Excellence Director to lead the optimization of workflows and play a key role in the continuous improvement across all projects and operations. This role ensures ...
Their creativity is the key to innovation through connected living, mobility, or industry. Let ... Lead Manufacturing Excellence We are seeking a Director of Operational Excellence to drive ...
Their creativity is the key to innovation through connected living, mobility, or industry. Let ... Lead Manufacturing Excellence We are seeking a Director of Operational Excellence to drive ...
Their creativity is the key to innovation through connected living, mobility, or industry. Let ... Lead Manufacturing Excellence We are seeking a Director of Operational Excellence to drive ...
Quick apply
Their creativity is the key to innovation through connected living, mobility, or industry. Let ... Lead Manufacturing Excellence We are seeking a Director of Operational Excellence to drive ...
Job Title Director, Operational Excellence & OEE Lead - Project Farma Location(s) Boston, Boston ... Innovation & Continuous Improvement: Seeks better ways, adapts to change and champions new ideas.
Job Title Director, Operational Excellence & OEE Lead - Project Farma Location(s) Boston, Boston ... Innovation & Continuous Improvement: Seeks better ways, adapts to change and champions new ideas.
Job Title Director, Operational Excellence & OEE Lead - Project Farma Location(s) Boston, Boston ... Innovation & Continuous Improvement: Seeks better ways, adapts to change and champions new ideas.
Job Title Director, Operational Excellence & OEE Lead - Project Farma Location(s) Boston, Boston ... Innovation & Continuous Improvement: Seeks better ways, adapts to change and champions new ideas.
Job Title Director, Operational Excellence & OEE Lead - Project Farma Location(s) Boston, Boston ... Innovation & Continuous Improvement: Seeks better ways, adapts to change and champions new ideas.
Job Title Director, Operational Excellence & OEE Lead - Project Farma Location(s) Boston, Boston ... Innovation & Continuous Improvement: Seeks better ways, adapts to change and champions new ideas.
Job Title Director, Operational Excellence & OEE Lead - Project Farma Location(s) Boston, Boston ... Innovation & Continuous Improvement: Seeks better ways, adapts to change and champions new ideas.
Job Title Director, Operational Excellence & OEE Lead - Project Farma Location(s) Boston, Boston ... Innovation & Continuous Improvement: Seeks better ways, adapts to change and champions new ideas.
Job Title Director, Operational Excellence & OEE Lead - Project Farma Location(s) Boston, Boston ... Innovation & Continuous Improvement: Seeks better ways, adapts to change and champions new ideas.
Job Title Director, Operational Excellence & OEE Lead - Project Farma Location(s) Boston, Boston ... Innovation & Continuous Improvement: Seeks better ways, adapts to change and champions new ideas.
Their creativity is the key to innovation through connected living, mobility, or industry. Let ... Lead Manufacturing Excellence We are seeking a Director of Operational Excellence to drive ...
Their creativity is the key to innovation through connected living, mobility, or industry. Let ... Lead Manufacturing Excellence We are seeking a Director of Operational Excellence to drive ...
We are seeking an Operational Excellence Director to lead the optimization of workflows and play a key role in the continuous improvement across all projects and operations. This role ensures ...
Quick apply
We are seeking an Operational Excellence Director to lead the optimization of workflows and play a key role in the continuous improvement across all projects and operations. This role ensures ...
... operations • Research and explore opportunities to increase effective use of labor • Create ... with Innovation Design to develop field testing protocols of new innovations • Evaluate ...
... operations • Research and explore opportunities to increase effective use of labor • Create ... with Innovation Design to develop field testing protocols of new innovations • Evaluate ...
Job Title Director, Operational Excellence & OEE Lead - Project Farma Location(s) Boston, Boston ... Innovation & Continuous Improvement: Seeks better ways, adapts to change and champions new ideas.
Job Title Director, Operational Excellence & OEE Lead - Project Farma Location(s) Boston, Boston ... Innovation & Continuous Improvement: Seeks better ways, adapts to change and champions new ideas.
Job Title Director, Operational Excellence & OEE Lead - Project Farma Location(s) Boston, Boston ... Innovation & Continuous Improvement: Seeks better ways, adapts to change and champions new ideas.
Job Title Director, Operational Excellence & OEE Lead - Project Farma Location(s) Boston, Boston ... Innovation & Continuous Improvement: Seeks better ways, adapts to change and champions new ideas.
Job Title Director, Operational Excellence & OEE Lead - Project Farma Location(s) Boston, Boston ... Innovation & Continuous Improvement: Seeks better ways, adapts to change and champions new ideas.
Job Title Director, Operational Excellence & OEE Lead - Project Farma Location(s) Boston, Boston ... Innovation & Continuous Improvement: Seeks better ways, adapts to change and champions new ideas.
Job Title Director, Operational Excellence & OEE Lead - Project Farma Location(s) Boston, Boston ... Innovation & Continuous Improvement: Seeks better ways, adapts to change and champions new ideas.
Job Title Director, Operational Excellence & OEE Lead - Project Farma Location(s) Boston, Boston ... Innovation & Continuous Improvement: Seeks better ways, adapts to change and champions new ideas.
Job Title Director, Operational Excellence & OEE Lead - Project Farma Location(s) Boston, Boston ... Innovation & Continuous Improvement: Seeks better ways, adapts to change and champions new ideas.
Job Title Director, Operational Excellence & OEE Lead - Project Farma Location(s) Boston, Boston ... Innovation & Continuous Improvement: Seeks better ways, adapts to change and champions new ideas.
Job Title Director, Operational Excellence & OEE Lead - Project Farma Location(s) Boston, Boston ... Innovation & Continuous Improvement: Seeks better ways, adapts to change and champions new ideas.
Job Title Director, Operational Excellence & OEE Lead - Project Farma Location(s) Boston, Boston ... Innovation & Continuous Improvement: Seeks better ways, adapts to change and champions new ideas.
Director Operational Excellence Innovation information
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$34K - $47.2K
4% of jobs
$47.2K - $60.5K
8% of jobs
$60.5K - $73.7K
11% of jobs
$75.8K is the 25th percentile. Wages below this are outliers.
$73.7K - $86.9K
12% of jobs
$86.9K - $100.1K
14% of jobs
The median wage is $101.9K / yr.
$100.1K - $113.4K
12% of jobs
$113.4K - $126.6K
13% of jobs
$129.9K is the 75th percentile. Wages above this are outliers.
$126.6K - $139.8K
9% of jobs
$139.8K - $153K
9% of jobs
$153K - $166.3K
5% of jobs
$166.3K - $179.5K
3% of jobs
$34K
$107.7K
$179.5K
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Director, Operational Excellence- Cell Therapy Manufacturing
Rockville, MD
$148 - $222K/hr
Full-time
Medical, Dental, Vision, Retirement, PTO
Posted 29 days ago
AstraZeneca rating
8.4
Based on 45 frontline employees who took The Breakroom Quiz
Job description
About the role, the Director, Operational Excellence (OE) leads the network-wide OE agenda for AstraZeneca's autologous Cell Therapy. You will establish basic conditions and eliminate waste across the vein-to-vein value stream. You will operate in a matrix with site-based OE Leads. It sets strategy, governs the improvement portfolio, and delivers measurable outcomes in cost, productivity, service, quality, safety, and compliance. Additionally, it builds sustainable capabilities for scale.
This role offers flexibility to be based in Rockville, MD or Tarzana, CA.
You Will:Lead end-to-end value stream mapping. Deploy Hoshin/strategy deployment to translate targets, such as COGM, capacity, and service, into a governed portfolio. This portfolio have clear owners, milestones, risks, and benefits. Additionally, create standardized COGM/productivity dashboards and benefit tracking with Finance.
Lead programs (cycle time, labor models, MES/EBR enablement, yield, changeovers/scheduling, deviation reduction, automation/technology insertion). Apply the AZ Lean Model (A3, VSM, standard work, daily/tier management, leader standard work, adapted SMED).
Facilitate development of business processes for training, batch execution, deviations, and patient/lot scheduling and logistics.
Lead Kaizen events; scale best practices across the Cell Therapy Development and Operations.
Define basic conditions for Cell Therapy Manufacturing Sites and build capability at all levels; coach leaders and value stream owners
Partner with Supply Chain to vein-to-vein flow, slotting, and cold-chain logistics, safeguarding Chain of Identity/Chain of Custody.
Ensure improvements uphold safety, patient focus, and cGMP for ATMPs (including GAMP and data integrity). Partner with Quality to reduce human error and increase First Pass Success and right-first-time performance.
Align senior leaders on priorities and resources; communicate impact through governance forums.
Bachelor's in engineering/Life Sciences or related; advanced degree preferred.
10+ years in GMP manufacturing; 5+ years leading programs.
Recognized Lean Six Sigma Black Belt or equivalent depth of OE expertise.
COGM/productivity improvements using lean, digital, and analytics.
Expertise in value stream management and lean (Hoshin, A3, VSM, standard work, tier/visual management, leader standard work); Genba execution.
Command of cGMP, data integrity, and GAMP; experience with MES/EBR/LIMS and other digital systems
Track record in cross-site program leadership, portfolio governance, and benefits realization with Finance.
Demonstrated experience in Influence without authority, change leadership, and process/project/risk/Analytical skills.
The annual base pay for this position ranges from $148 to $222K. Our positions offer eligibility for multiple incentives an opportunity to receive short-term incentive bonuses, equity-based awards for salaried roles and commissions for sales roles. Benefits offered include qualified retirement programs, paid time off (i.e., vacation, holiday, and leaves), as well as health, dental, and vision coverage in accordance with the terms of the applicable plans.
Date Posted
13-Aug-2026Closing Date
Our mission is to build an inclusive environment where equal employment opportunities are available to all applicants and employees. In furtherance of that mission, we welcome and consider applications from all qualified candidates, regardless of their protected characteristics. If you have a disability or special need that requires accommodation, please complete the corresponding section in the application form.
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About AstraZeneca
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AstraZeneca is a global, science-led, patient-focused biopharmaceutical company that focuses on the discovery, development and commercialization of prescription medicines for some of the world's most serious diseases. But we're more than one of the world's leading pharmaceutical companies. A place built on courage, curiosity and collaboration - we make bold decisions driven by patient outcomes. Empowered to lead at every level, free to ask questions and take smart risks that write the next chapter for our pipeline and Oncology team. Make a meaningful impact that brings real benefits to society. By applying your knowledge of data, you will help to redefine our industry and ultimately save lives. Work with experts who share a common goal: to accelerate the potential of medicines and the science of tomorrow.
Industry
Pharmaceutical product wholesalers and pharmaceutical and medicine manufacturing
Company size
10,000+ Employees
Headquarters location
Cambridge, Cambridgeshire, GB