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Director Lab Operations Jobs in Boston, MA (NOW HIRING)

Biocytogen

Lab Operations Associate

Waltham, MA

We are looking for a self-directed, well-organized individual who enjoys working with scientists to ... Manage several laboratory operations, equipment and device maintenance, lab safety procedures, and ...

Biocytogen

Lab Operations Associate

Waltham, MA · On-site

We are looking for a self-directed, well-organized individual who enjoys working with scientists to ... Manage several laboratory operations, equipment and device maintenance, lab safety procedures, and ...

Biocytogen

Lab Operations Associate

Waltham, MA · On-site

We are looking for a self-directed, well-organized individual who enjoys working with scientists to ... Manage several laboratory operations, equipment and device maintenance, lab safety procedures, and ...

Vrtx

Director, Lab Systems Engineering

Boston, MA · On-site

$115K - $150K/yr

General / Position Summary The Director, Business Engagement & Technology, Lab Solutions will lead ... Ensure stable, secure, and compliant laboratory technology operations across both IT andOT ...

NorthEastern

Instructional Lab Technician

Boston, MA · On-site

$20.75 - $27.50/hr

Space Planning, Facilities Support & Safety : * Assist the Assistant Director for ECE Labs and Safety with lab space planning, facility improvements, and operational upgrades. * Coordinate with ...

Dyne Therapeutics

Senior Lab Manager

Waltham, MA · On-site

The Senior Lab Manager works with the Lab Operations Associate Director to provide a smoothly operating laboratory for our scientific personnel. This individual needs to be willing to learn, adapt ...

Merck Group

Head of Science Operations

Billerica, MA · On-site

Lab operations governance Develop and maintain SOPs, QC metrics, safe-lab practices, and data ... Direct influence over how Chemistry and Biology science is designed, executed, and connected to AI ...

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All JobsDirector Lab Operations JobsDirector Lab Operations Jobs in Boston, MA

Director Lab Operations information

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How much do director lab operations jobs pay per year?

As of Jul 1, 2026, the average yearly pay for director lab operations in Boston, MA is $116,984.00, according to ZipRecruiter salary data. Most workers in this role earn between $82,000.00 and $147,200.00 per year, depending on experience, location, and employer.

What is the highest paying job in a laboratory?

In laboratory settings, the highest paying roles are often senior management positions such as Laboratory Directors or Chief Scientific Officers, who oversee operations and research strategies. These roles typically require advanced degrees, extensive experience, and leadership skills, and they can command salaries significantly higher than other laboratory positions.

What are some of the biggest challenges a Director of Lab Operations might face in managing multidisciplinary teams?

A Director of Lab Operations often oversees teams with diverse scientific backgrounds and expertise, which can present challenges in ensuring effective communication and collaboration. Balancing competing priorities, such as meeting research goals while maintaining compliance with safety and quality standards, is also common. Additionally, adapting to rapidly changing technologies and regulatory requirements requires strong leadership and the ability to foster ongoing professional development within the team. Building a cohesive culture and aligning team efforts with broader organizational objectives are key to success in this role.

What does a laboratory director do?

A laboratory director oversees the daily operations of a laboratory, ensuring compliance with safety and quality standards, managing staff, and coordinating testing procedures. They are responsible for maintaining accurate records, implementing protocols, and ensuring the lab meets regulatory requirements, often requiring strong leadership, technical expertise, and relevant certifications. The role involves strategic planning and quality assurance to support reliable testing outcomes.

What is the difference between Director Lab Operations vs Laboratory Manager?

AspectDirector Lab OperationsLaboratory Manager
CredentialsTypically requires a bachelor's degree in a science or related field, often with advanced degrees and leadership experienceUsually requires a bachelor's degree in a science or related field, with some roles preferring a master's
Work EnvironmentOversees multiple labs or departments, strategic planning, and high-level operationsManages daily lab activities, staff, and workflow within a specific lab or department
Employer & Industry UsageCommon in large biotech, pharmaceutical, and research organizationsFound in hospitals, clinical labs, and smaller research facilities

The main difference is that the Director Lab Operations focuses on strategic oversight and high-level management across multiple labs, while the Laboratory Manager handles daily operations and staff within a specific lab. Both roles require strong scientific knowledge, but the director position emphasizes leadership and planning.

How much does a laboratory director make in the US?

A laboratory director in the US typically earns between $90,000 and $150,000 annually, depending on factors such as experience, location, and the size of the laboratory. Senior directors or those in specialized fields may earn higher salaries, often supplemented with benefits and bonuses.

Is a director of operations a high position?

A director of operations is a senior leadership role responsible for overseeing daily business activities, strategic planning, and operational efficiency. It is generally considered a high-level position within an organization, often reporting to executive management or the CEO.

What does a Director of Lab Operations do?

A Director of Lab Operations oversees the daily management and strategic direction of laboratory facilities. Their responsibilities include supervising lab staff, ensuring compliance with safety and regulatory standards, managing budgets, and optimizing workflow efficiency. They also play a key role in implementing new technologies, maintaining equipment, and collaborating with other departments to support research or clinical goals. This position typically requires strong leadership skills and experience in scientific or clinical laboratory environments.

What are the key skills and qualifications needed to thrive as a Director of Lab Operations, and why are they important?

To thrive as a Director of Lab Operations, you need a robust background in laboratory science, operational management experience, and typically a relevant advanced degree such as a PhD or MSc. Familiarity with laboratory information management systems (LIMS), regulatory compliance standards (e.g., CLIA, CAP), and quality control protocols is essential. Strong leadership, problem-solving, and communication skills help drive team performance and foster a culture of safety and efficiency. These competencies are crucial for ensuring high-quality results, regulatory compliance, and effective lab operations.
What are the most commonly searched types of Lab Operations jobs in Boston, MA? The most popular types of Lab Operations jobs in Boston, MA are:
What cities near Boston, MA are hiring for Director Lab Operations jobs? Cities near Boston, MA with the most Director Lab Operations job openings:
Director Lab Operations jobs near you
Senior Director, Lab-to-Product Platform and Operations Technology

Senior Director, Lab-to-Product Platform and Operations Technology

Alnylam Pharmaceuticals

Cambridge, MA • On-site

$254K - $266K/yr

Full-time

Medical, Dental, Vision, Life, Retirement, PTO

Posted 28 days ago

Job description

Overview
Alnylam is seeking a strategic and pragmatic technology leader to serve as Senior Director, Lab-to-Product Platform & Operations Technology, a role that owns the core digital platforms, services, lab computing environment, and operational technologies that power laboratory operations across Research, CMC, and Quality Control, as well as digital enablement of plant-floor (shopfloor) operational technologies (OT).
This scope extends beyond internal operations to include operational technology enablement, secure data exchange, workflow interoperability, and validated system readiness that support external execution partners-including CROs, external research labs, development collaborators, contract testing labs, and external manufacturing partners.
This role is focused on operational platforms-the systems, integrations, partner connectivity, validated interfaces, computing environments, and services that ensure labs, plants, and external partners run reliably, compliantly, and efficiently. Scientific research platforms and enterprise manufacturing systems (e.g., MES and supply chain planning) are owned by their respective teams. This role ensures seamless interoperability, operational data flow, OT enablement, and validated integration frameworks across internal and external environments while maintaining clear ownership boundaries.
This role is responsible for building and operating a modern Lab-to-Product operational platform that connects experiment execution, sample and materials workflows, QC testing, and plant operations - regardless of whether those activities occur internally or through external partners.
This hybrid role is based primarily in Cambridge, MA, with regular engagement at our Cambridge labs and Norton/Alewife manufacturing sites, and direct interaction with external execution partners.
Key Responsibilities
1. Own and operate core lab, plant, and external partner operational platforms
  • Lead the digital capabilities that support lab operations across Research, CMC, and QC, including LIMS, ELN/LES, sample & inventory management, registration, lab automation enablement, instrument integration, lab computing, lab system validation, and operational data capture.
  • Oversee plant-floor operational technologies (OT) such as equipment/instrument connectivity, environmental and facility monitoring interfaces, materials tracking, barcode/RFID data capture, and automated data collection (excluding MES and supply chain systems).
  • Enable operational technology connectivity, workflow interoperability, and validated data exchange with CROs, external research labs, development partners, contract testing labs, and external manufacturers.
  • Support validated data handoffs, sample/material traceability, workflow tracking, and operational interfaces across hybrid (internal + external) execution models.
  • Ensure reliability, compliance, validated state, lifecycle management, and service continuity across internal systems and partner-connected operational interfaces.
  • Oversee lab/operational system validation activities in partnership with Quality to maintain GxP compliance and data integrity across all execution environments.
2. Build the Lab-to-Product Platform (Internal + External Execution Model)
  • Architect and deliver the operational platform that connects experiment execution → sample workflows → QC testing → plant operational activities → external execution and release workflows.
  • Provide reusable platform components including metadata standards, workflow modules, instrument connectors, validated integration frameworks, and operational data pipelines that external partners can adopt or interface with.
  • Ensure seamless interoperability with:
    • Scientific platforms owned by ReDev Technology
    • Manufacturing/enterprise systems owned by Manufacturing/CMC/Supply Chain Technology
    • External research, development, QC, and manufacturing partner systems
  • Establish secure, scalable, validated patterns for partner connectivity (e.g., APIs, secure file exchange, partner portals, event/data streams).
3. Lead a high-performing operations-focused technology team
  • Build and develop talent and capabilities across product management, engineering/architecture, lab computing support, instrument connectivity, and operational platform engineering.
  • Define support, governance, onboarding, and escalation models for external partners, including SLAs and service continuity plans in collaboration with ReDev and TOQ.
  • Drive a culture centered on operational excellence, validation rigor, compliance, accountability, and pragmatic problem-solving.
  • Establish standards, governance, and best practices for lab/plant operational technology, including lab system validation frameworks.
4. Deliver robust operational data integration
  • Work closely with the Data & AI organization to ensure operational data - including external partner-generated data - is structured, contextualized, and AI-ready.
  • Implement consistent metadata, data capture, and validated interface practices across internal and external operations.
  • Enable cross-system visibility into workflows, materials, samples, and processes across internal labs, plants, and external partner networks.
5. Partner deeply across the enterprise and external ecosystem
  • Collaborate with ReDev Technology, Manufacturing/CMC/Supply Chain Technology, Quality, Tech Operations, Data/AI, Infrastructure, and Security to ensure cohesive integration and operational excellence.
  • Partner with ReDev and TOQ to define and support the digital operating model for CROs, external labs, contract testing labs, and external manufacturers.
  • Maintain clear ownership boundaries while ensuring the operational platform enables distributed execution.
  • Serve as a trusted partner to scientific, operational, and quality stakeholders - internally and externally.

Qualifications
Required
  • Bachelor's degree in Computer Science, Engineering, Life Sciences, or related field (or equivalent experience).
  • 15+ years of progressive leadership experience in laboratory informatics, scientific operations, OT/plant-floor (shop floor) automation enablement, or manufacturing operational technology in biotech/pharma.
  • Deep expertise with lab operations systems (e.g., LIMS, ELN/LES, sample/inventory management, workflow orchestration), lab computing environments, instrument integration, and validated interfaces.
  • Experience supporting operational workflows across internal and external networks, including CROs, external research labs, contract testing labs, and/or external manufacturers.
  • Strong understanding of GxP, Computer System Validation (CSV), data integrity, interoperability, and operational data management.
  • Experience leading product management and engineering/architecture teams in regulated and non-regulated environments.
  • Proven track record delivering enterprise-scale operational platforms with measurable impact.
  • Exceptional communication, influence, and stakeholder-management skills.
  • Ability to balance long-term strategy with pragmatic execution.

Preferred
  • Advanced degree in Computer Science, Engineering, or Life Sciences.
  • Experience supporting RNAi, oligonucleotide, or other advanced modality development or manufacturing.
  • Familiarity with modern integration architectures (APIs, event-driven patterns), lab automation frameworks, OT/plant-floor technologies, and emerging AI-driven automation.
  • Experience in environments where R&D, CMC, QC, Manufacturing, and external partners depend on shared operational platforms and validated systems.

#LI-Hybrid
#LI-LN1
U.S. Pay Range
$226,800.00 - $306,800.00
The pay range reflects the full-time base salary range we expect to pay for this role at the time of posting. Base pay will be determined based on a number of factors including, but not limited to, relevant experience, skills, and education. This role is eligible for an annual short-term incentive award (e.g., bonus or sales incentive) and an annual long-term incentive award (e.g., equity).
Alnylam's robust Total Rewards package is designed to support your overall health and well-being. We offer comprehensive benefits including medical, dental, and vision coverage, life and disability insurance, a lifestyle reimbursement program, flexible spending and health savings accounts and a 401(k)with a generous company match. Eligible employees enjoy paid time off, wellness days, holidays, and two company-wide recharge breaks. We also offer generous family resources and leave. Our commitment to your well-being reflects our belief that caring for our people fuels the impact we create together.
Learn more about these and additional benefits offered by Alnylam by visiting the Benefits section of the Careers website: https://www.alnylam.com/careers
About Alnylam
We are the leader in RNAi therapeutics - a revolutionary approach with the potential to transform the lives of people with rare and common diseases. Built on Nobel Prize-winning science, Alnylam has delivered the breakthroughs that made RNAi therapeutics possible and are just at the beginning of what's possible. Our deep pipeline, late-stage programs, and bold vision reflect our core values: fierce innovation, passion for excellence, purposeful urgency, open culture and commitment to people. We're proud to be a globally recognized top employer, where an authentic, inclusive culture and breakthrough thinking fuel one another.
At Alnylam, we commit to an inclusive recruitment process and equal employment opportunity. Qualified applicants will receive consideration for employment without regard to their sex, gender or gender identity, sexual orientation, race, color, ethnicity, national origin, ancestry, citizenship, religion, creed, physical or mental disability, pregnancy status or related conditions, genetic information, veteran or military status, marital or familial status, political affiliation, age, or any other factor protected by federal, state, or local law. Alnylam is an E-Verify Employer.

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